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In this study, the Web Camera System is implemented and simulated on two different architectures. In the one architecture, a Web-server and Camera-server are implemented on the same system, and the system transfers motion picture which compressed to JPEG file to users on the WWW(World Wide Web), In the other architecture, the Web-server and Camera-server are implemented on different systems, and the motion picture is transferred from the Camera-server to Web-server, and finally to users. In order to compare system performance between two architecture, data traffic is measured and simulated in the unit of byte per second and frame per second.
In order to investigate the effects of Kaejibokryungwhan, Sobokchugeotang and Dohongsamultang on mesangial cell proliferation and fibronectin synthesis, laboratory study was performed. The results are summarized as follows; 1. Mesangial cell proliferation was significantly decreased in the Kaejibokryungwhan group and the Dohongsamultang group compared with the Control group. In the Sobokchugeotang group, the mesangia1 cell proliferation activity was lesser than Control group, but it was statistically non-significant. In Kaejibokryungwhan group, the Sobokchugeotang group and Dohongsamultang group, mesangial cell proliferation was significantly decreased compared with the Hydrocortisone group 2. In the group, which contained fetal bovine serum, fibronectin synthesis was decreased in the Kaejibokryungwhan group, the Sobokchugeotang group and Dohongsamultang group compared with Control group, but the difference was statistically non-significant. In Kaejibokryungwhan group, Sobokchugeotang group and Dohongsamultang group, fibronectin was less decreased compared with that of Hydrocortisone group. 3. In the group, which contained fetal bovine serum, fibronectin synthesis was significantly decreased in Kaejibokryungwhan group and Sobokchugeotang group than those of Control group. In Dohongsamultang group, the fibronectin synthesis was decreased than Control group, but the difference was statistically non-significant. In Sobokchugeotang group, the fibronectin synthesis was decreased than Hydrocortisone group, but it was statistically non-significant. According to the above results, the mesangial cell proliferation and fibronectin systhesis could be reduced by Kaejibokryungwhan group significantly.
본 논문에서는 개념 기반 질의-응답 시스템에서의 정답 추출 방법에 대하여 기술한다. 개념 기반 질의-응답 시스템은 개념 정보를 이용하여 해답을 추출하는 시스템을 말하며, 질의분석을 통해 분류되고 추출된 개념 그에 따른 정답 추출 규칙을 이용하여 정답을 추출하는 방법과 시스템에 대하여 연구하였다. 질의에 대한 정답이 들어 있는 문서들을 분석하여 정답 추출 규칙을 작성한다. 규칙은 개념과 구문정보를 포함하고 있으며 작성된 규칙을 통하여 문서로부터 정답후보를 생성하고 정답을 선택한다. In this paper, we describe a method of answer extraction on a concept-based question-answering system. The concept-based question answering system is a system which extract answer using concept information. we have researched the method of answer extraction using concepts which analyzed and extracted through question analysing with answer extracting rules. We analyzed documents including answers and then composed answer extracting rules. Rules consist of concept and syntactic information, we generated candidates of answer through the rules and then chose answer.
본 연구에서는 하고초의 지표성분인 triterpenic acids 5종을 컬럼 크로마토그래피와 역상 HPLC를 이용하여 추출 및 분리했고, 이들 성분의 순도는 90% 이상임을 HPLC를 이용하여 확인했다. 고속원자충돌 이온화법-고분해능 질량분석기(FAB-HRMS)를 사용하여 지표성분의 분자량 및 원소조성을 결정했으며, 지표성분의 구조 분석은 FAB-MS/MS 의해 음이온 및 양이온 모드에서 수행하였다. Triterpenic acid류의 충돌유발분해(collision-induced dissociation, CID) 탄뎀 질량분석(MS/MS) 스펙트럼에서 protonated molecule인 [M+H]? 및 deprotonated molecule인 [M-H]? 이온의 CID는 주로 retro Diels-Alder (RDA), 탈수 (dehydration) 및 탈탄산(decarboxylation) 반응에 의한 다양한 생성이온들이 나타났다. 특히, [M-H]? 이온의 CID-MS/MS 스펙트럼에서는 charge-remote fragmentation (CRF) 현상에 의한 이온들도 특성이온으로 나타났다. 이들 CID-MS/MS 스펙트럼의 해석을 통하여 하고초의 지표성분인 triterpenic acids의 구조 규명을 수행하였다. Five triterpenic acids as marker compounds were extracted and isolated from Prunellae Spica by column chromatography and reversed-phase high-performance liquid chromatography (HPLC), and their purity was determinated by HPLC (purity ≥ 90%). Molecular weight and elemental compositions of the five marker compounds were determined by fast atom bombardment high-resolution mass spectrometry (FAB-HRMS). The structural determination of the five marker compounds was carried out fast atom bombardment collision-induced dissociation tandem mass spectrometry (FAB-CID-MS/MS). The collision-induced dissociation (CID) of protonated molecules [M+H]? and deprotonated molecules [M-H]? produced diverse product ions due mainly to retro Diels-Alder reaction (RDA), dehydration and decarboxylation. Moreover, the CID-MS/MS spectra of the [M-H]? ions were observed charge-remote fragmentation (CRF) patterns. On the basis of interpretation of CID-MS/MS spectra, structural elucidation of triterpenic acids isolated from Prunellae Spica was clearly performed.
안영민 ( Young Min Ahn ), 조경기 ( Kyung Gi Cho ), 이창미 ( Chang Mi Lee ), 방종희 ( Joung Hee Bang ), 류명이 ( Myung Yi Ryu ), 김세중 ( Se Joong Kim ), 서혜영 ( Hae Young Suh ), 김승업 ( Seung Eop Kim ) 대한뇌종양학회 2006 대한뇌종양학회지 Vol.5 No.2
Introduction : Despite the advanced neurosurgical techniques and various multimodal therapeutic approach have been developed for malignant gliomas, these can not save the patients from the tumors due to infiltrating behavior of glioma cells. Here the authors investigated the possibility of treatment for the malignant gliomas with neural stem cell(HB1.F3) transduced with suicidal gene using the tropism of stem cells. Materials and Methods : E.coli cytosine deaminase(CD) is an enzyme that catalyzes the conversion of noncytotoxic 5- FC to the cytotoxic and radiosensitizing drug 5-FU. Cytotoxic 5-FU and its toxic metabolites can readily diffuse into surrounding tumor cells giving CD. HB1.F3 were transduced with retroviral vectors expressing the E.coli CD. Rats were implanted with U373MG, U251MG human glioblastoma(hGM) cell line and F3/CD were injected directly into the tumor mass 6 days later. The rats with tumors were injected IP 5-FC or saline daily for 7 days since 6 days after implantation of tumors. Results : HB1.F3 which were injected into the contralateral hemisphere to the tumor implantation site migrated through the corpus callosum to the tumor cells 3 days after hGM transplantation . The growth inhibition of 5-FU treated cells in comparison to untreated controls was remarkable in vitro. The tumor mass in the rats with transplantation of F3/CD were reduced markedly in size comparing to that with F3 after injection of 5-FC . Conclusions : The human neural stem cells can trace to the glioma cells in the rat brain. 5-FC systemic treatment with direct transplantation of F3/CD reduces tumor size. Our data indicates that suicide gene therapy using neural stem cells would be promising as a new therapeutic approach for malignant glioma.
원저 : 발기불전 환자의 한방치료 전후 적외선 체열촬영을 이용한 음경온도의 변화 ( Original Article : The Change of the Temperature of External genitalia at the Patients with Impotence by Using Penile DITI / Before and After Oriental Medicine Treatment )