성인 복부에 발생한 비정형 Spitz 모반 1예

오승민,안혜진,신민경,정기헌 대한피부과학회 2022 대한피부과학회지 Vol.60 No.8

Atypical Spitz nevi are defined as melanocytic proliferations with intermediate histopathologic features between thoseof Spitz nevi and Spitzoid melanoma. Diagnosis of atypical Spitz nevi can be challenging, and there remains a lackof consensus among dermatopathologists regarding an exact definition. A 59-year-old female presented with anasymptomatic, 1.2-×0.8-cm-sized erythematous nodule on the abdomen. Histopathological findings demonstratedspindle and epithelioid cells with prominent nucleoli in nests from the dermo-epidermal junction to the reticulardermis with a few epidermal pagetoids spread. Immunohistochemical analysis revealed positive S-100, negativeHMB-45, and a Ki-67 index of 10%. A final diagnosis of atypical Spitz nevus was made, and the tumor was resectedvia total surgical excision. Herein, we report a rare case of adult-onset atypical Spitz nevus on the abdomen.

Lauritzen과 Jaeger의 내러티브 설계 모형을 적용한 초등학교 6학년 도덕과 ‘편견’ 단원의 설계

오승민 한국내러티브교육학회 2014 내러티브와 교육연구 Vol.2 No.2

최근 내러티브를 활용하여 교육과정을 설계하는 방안에 대하여 활발한 논의가 이루어지고 있다. 내러티브 교육과정 설계는 내러티브라는 인간의 인식론적 도구를 바탕으로 교육과정의 목표, 내용, 교수, 평가의 일련의 과정을 정렬하는 과정이다. 본 연구는 내러티브 교육과정 설계를 위한 한 단원의 설계안을 제시함으로써 교육현장에서 내러티브 교육과정을 쉽게 설계하여 교사와 학생들의 배움을 촉진시키는데 목적이 있다. 본 연구의 목적을 달성하기 위하여 2장에서는 내러티브 교육과정의 이론적 측면을 다루었으며, 3장에서는 내러티브 교육과정 설계의 방향과 원리를 제시하였다. 4장에서는 Lauritzen과 Jaeger의 내러티브 설계모형을 적용하였으며 마지막에는 설계안을 시각화 하는 템플릿을 제시하였다. 내러티브 교육과정이 현장에서 내러티브의 교육목표 달성을 위한 교수-학습과정의 하나의 안으로 활용하는 것은 현재의 지식전달중심의 교육과정을 개선할 수 있을 것으로 기대한다. The purpose of this study is to explore the direction of design for narrative curriculum. In this study, I designed the curriculum using narrative, a subject of current active research. Narrative curriculum refers to the structure in which students' education opportunity can be organized constructively and analytically utilizing narrative, so that their knowledge and experience can be continually reconstructed. Narrative itself means a curriculum. In the study, the five-stage design template of Lauritzen and Jaeger(1997) model that includes the context, inquires, goals filter, explorations and culminations was applied to designing practical education. In chapter 4, the case of designing the theme of 'diverse culture, happy world' that deals with overcoming prejudices on different cultures in the moral course for elementary 6th grade students was discussed. In specific, the educational content of the designed template include the process of solve problems, The critically, creatively, use technology, communicate, quantify, direct own learning, and cooperate. In applications on individual and social aspects, ability to deliberate on public issues, to interpret human experience; to understand diversity, health habits, Science/Math relationships, humanities. Implementing narrative curriculum based on practical educational view in a country with nation-oriented curriculum development system such as Korea, requires mutual adaptation perspectives for each sides. As such, the role of teachers is a subjective practitioner with the ability of reconstructing curriculum. Finally, the effect from narrative curriculum based on the social practices can be analyzed from the measurement of output, evaluation of curriculum through evaluating process, investigation of students' level of interest on study, and observation on scenes from classes. Education in perspective of practices is an initiation process of practices for the better quality of life, in which individuals can form totality of their lives while studying the tradition. Thus, narrative curriculum is will help professor-learner develop narrative capability.

The Findings of Reflectance Confocal Microscopy in the Diagnosis of Green Nail Syndrome

오승민,안혜진,신민경 대한의진균학회 2021 대한의진균학회지 Vol.26 No.4

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[공인회계사] 성공적인 작은 하루가 모여

오승민 회경사 2015 月刊 會計 Vol.23 No.2

랫드에서 l-muscone의 급성독성 및 아급성독성시험 연구

오승민,연제덕,남혜운,박대규,조명행,정규혁 성균관대학교 약학연구소 1998 成均藥硏論文集 Vol.10 No.1

l-Muscone is synthesized for use as substitutive material of musk which is the active ingredient of woohwangchungsimwon. The objective of this investigation was to evaluate the acute and subacute toxicity of l-muscone in rats. In oral acute toxicity test, SPF Sprague-Dawley male and female rats were gavaged with l-muscone of two doses(0, 5.0g/㎏). No dead animal and abnormal autopsy findings were found in control and treated group. Body weights were slightly decreased in both sexes of rats treated with 5.0g/㎏. Therefore, oral LD_50 of l-muscone was consider to be higher than 5.0g/㎏ in male and female rats. In intraperitoneal acute toxicity test, rats were injected intraperitoneally with dosages of 0, 1,000, 1,316, 1,732, 2,279 and 3,000 ㎎/㎏. Decreased body weights and motor activities were observed at high dose group. Intraperitoneal LD_50 of l-muscone were 1,920 ㎎/㎏ in male and female rats. In the subacute study. l-muscone was administrated orally to both sexes of rats for 4 weeks as several doses(0, 10, 100 and 1,000 ㎎/㎏). There were neither dead animals nor significant changes of body weights during the experimental period. In addition, no differences were found between control and treated groups in clinical signs, urinalysis, hematology, serum biochemical analysis, and other findings. Above data suggest that no observed adverse effect level of l-muscone in rats might be over 1,000 ㎎/㎏/day in this study.

우리나라 여성의 임신 중 커피 음용 실태와 산모혈 및 제대혈 중 지질치 변화에 미치는 영향

오승민,정규혁 성균관대학교 약학연구소 1998 成均藥硏論文集 Vol.10 No.1

To investigate the effect of coffee consumption during pregnancy on serum lipids in maternal and infants' umbilical cord blood, 76 cases of newborn infants and women delivered of a child who had delivered at hospital located in Chung-Ju city from Feb. 1. 1996 to Aug. 31. 1996 were studied. The gestational ages of cases were 37 to 42 weeks and the average maternal ages were 28.3±4.63 years old without any other medical or obstetric problems. Infants' Apgar scores and birth weights were decreased by above 3 cups per day of coffee consumption during pregnancy. No relationships between coffee consumption during pregnancy and maternal serum lipid levels were observed. However, serum total cholesterol and LDL-cholesterol levels in infants' umbilical cord were significantly increased with increasing coffee consumption during pregnancy. In contrary to coffee consumption, alcohol drinking habits affected maternal serum lipid levels but not serum lipid levels in infants' umbilical cord blood. Coffee consumption during pregnancy increased caffeine concentration in infants' umbilical cord blood. These results suggest that caffeine from maternal consumption of coffee can easily pass to the fetus and significantly affect serum lipids levels in infants' umbilical cord blood rather than those in maternal blood.

랫드에서 l-muscone의 급성독성 및 아급성독성시험 연구

오승민,연제덕,남혜윤,박대규,조명행,정규혁 한국독성학회 1997 Toxicological Research Vol.13 No.4

l-Muscone is synthesized for use as substitutive material of musk which is the active ingredient of woohwangchungsimwon. The objective of this investigation was to evaluate the acute and subacute toxicity of l-muscone in rats. In oral acute toxicity test, SPF Sprague-Dawley male and female rats were gayaged with l-muscone of two doses(0, 5.0 g/kg). No dead animal and abnormal autopsy findings were found in control and treated group. Body weights were slightly decreased in both sexes of rats treated with 5.0 g/kg. Therefore, oral $LD_{50}$ of l-muscone was consider to be higher than 5.0 g/kg in male and female rats. In intraperitoneal acute toxicity test, rats were injected intraperitoneally with dosages of 0, 1,000, 1,316, 1,732, 2,279 and 3.000 mg/kg. Decreased body weights and motor activities were observed at high dose group. Intraperitoneal $LD_{50}$ of l-muscone were 1,920 mg/kg in male and female rats. In the subacute study, l-muscone was administrated orally to both sexes of rats for 4 weeks as several doses(0, 10, 100 and 1,000 mg/kg). There were neither dead animals nor significant changes of body weights during the experimental period. In addition, no differences were found between control and treated groups in clinical signs, urinalysis, hematology, serum biochemical analysist and other findings. Above data suggest that no observed adverse effect level of l-muscone in rats might be over 1,000 mg/kg/day in this study.

산업폐수처리장 방류수의 내분비계 장애작용 평가

오승민,김기서,유병택,장형석,이희성,정규혁 한국환경독성학회 2004 환경독성보건학회지 Vol.19 No.4

This study was designed to investigate potential endocrine disrupting effects of several industrial wastewater effluents discharged from cosmetic, plaiting, paint, textile industry using EROD bioassay and E-Screen assay The results of E-screen assay showed that textile industrial wastewater could act as a full agonist and cosmetics and plaiting industrial wastewater could act as a partial agonist On the contrary, the wastewater discharged from paint industry did not show any estrogenic effect Estrogenic activity in the effluents of cosmetic and paint industrial wastewater was lower than that in the influents indicating that the wastewater treatment process minimized the effects of discharges on water quality Despite of these results, it was recognized that wastewater treatment was not always minimize toxic impact In this study, increased estrogenic effect was observed in the effluents of plating and textile wastewater, and EROD activity was increased in the effluents of cosmetic and plating wastewater.

QAR 전략이 초등학교 5학년 학생의 과학적 태도에 미치는 영향

오승민,정진우,김형범,정소피아(선경) 대한지구과학교육학회 2016 대한지구과학교육학회지 Vol.9 No.2

The purpose of this study is to examine the effects of applying the Question-Answer Relationship (QAR)strategy on the attitude toward science of the elementary fifth grade students whose learning styles have beenidentified. The population of the study constitutes the total of 97 elementary fifth grade students who wereassigned into a comparison (n=48) or experimental group (n=49). To understandhow the QAR strategy potentially influencedscientific attitude, both groups were surveyedin the areas of scientific attitude before and after the experiment. TheKolb's Test was used to identifythe students’ learning stylein the experimental group. According tothe learners' learning style, the results have been compared and analyzed. The results of this study are as follows:First, the findings revealed a significant difference in the experimental group students’ attitude toward sciencecompared to the comparison group. Second, four learning styles were identified among the studentsin theexperimental group: a) Accommodators (46.9%), b) Convergers (24.5%), c) Divergers (20.4%), and d) Assimilator (8.2%). Following the data analysis, there was no meaningful statistical difference between four groups oflearning styles with respect to their scientific attitude.Applyingthe QAR strategy in a science class seemed toimprove the accommodators, convergers, and divergers’ scientific attitude positively.

빠른 응답특성을 갖는 DC/DC 컨버터 하이브리드 전류 모드 제어기

오승민,백승우,김학원,조관열 전력전자학회 2019 전력전자학회 논문지 Vol.23 No.2

A wide-bandwidth current controller is required for fast charging/discharging of super capacitor applications. Peak current mode is generally used to accomplish fast charging/discharging because this mode has fast response characteristics. However, the peak current mode control must have a slope compensation function to restrain sub-harmonics oscillation. The slope must be changed accordingly if the controlled output voltage is varied. However, changing the slope for every changed output voltage is not easy. The other solution, selecting the slope as the maximum value, causes a slow response problem to occur. Therefore, we propose a hybrid mode controller that uses a peak current and a newly specified valley current. Through the proposed hybrid mode control, the sub-harmonic oscillation does not occur when the duty is larger than 0.5 because of the fast response.