유엔아시아ㆍ極東犯罪防止硏修所

丁東鎭(Jong Dong Jin) 한국형사법무정책연구원 1992 형사정책연구 Vol.11 No.-

알루미늄용 산성탈지제의 제조 및 탈지특성

정동진 ( Dong Jin Chung ),박형진 ( Hyong Jin Park ),김성래 ( Sung Rae Kim ),정충호 ( Choong Ho Jung ),우종표 ( Jong Pyo Wu ),함현식 ( Hyun Sik Hahm ),박홍수 ( Hong Soo Park ) 한국유화학회 2003 한국응용과학기술학회지 Vol.20 No.1

N/A Acidic degreasing agent(AADA) was prepared by blending sorbitol, Newpol PE-68, Na-dioctyl sulfosuccinate, Tetronix T-701, MJU-100A, n-octanoic acid, and phosphoric acid, The physical properties of AADA tested with aluminum specimen shdhowed the following results ; when 3wt% AADA-5 was performed at 70℃, the degreasing rate was 95% which is comparitively good, and the percentage of etching was 0.277% which was found to be less than that of commercialized product. when 20wt% of AADA-5 was added at 65℃, the percentage of derusting was 91% and the good defoaming effect proved by following low foaming power tests respectively : Ross and Miles, and Ross and Clark methods.

인슐린비의존형 당뇨병 환자에서 단시간 운동부하에 의한 혈소판응집능의 감소

정동진(Dong Jin Chung),장현주(Hyun Ju Jang),안재수(Jae Su An),최종상(Jong Sang Choi),윤재영(Jae Young Yoon),정민영(Min Young Chung),이태희(Tai Hee Lee) 대한내과학회 1991 대한내과학회지 Vol.41 No.2

N/A Increased platelet aggregation in diabetes mellitus is considered to be one of the etiologic factors of diabetic microangiopathy. The mechanism influencing platelet aggregation by physical exercise in non-insulin-dependent diabetes mellitus (NIDDM) is poorly understood. This study was performed to evaluate the effectiveness of short-term exercise on platelet aggregation in patients with non-obese, non-insulin-dependent diabetes mellitus compared with the normal group. Before and after submaximal exercise using ergometer, platelet aggregation responses to adenosine diphosphate (ADP), collagen, and epinephrine were measured, and the following results were obtained. 1) In platelet aggregation test, in NIDDM patients (n=45), the maximal platelet aggregations [to ADP; 78.7% (p<0.01), to epinephrine; 74.5% (p<0.05)] were significantly higher than those [to ADP; 65.1%, to epinephrine; 67.3%] of control subjects(n=15). 2) In control subjects (n =9), platelet aggregations after exercise was not significantly changed [before exercise; ADP 65.8±3.55%, collagen 70.2±2.35%, epinephrine 58.3±6.08%, after exercise; ADP 68.0±2.84%, collagen 68.9±2.46%, epinephrine 59.5±5.73%, respectively]. 3) In NIDDM patients (n =13), platelet aggregations to ADP and collagen after exercise were significantly decreased [before exercise; ADP 73.4±3.98%, collagen 79.3±4.24%, epinephrine 72.8±3.57%, after exercise; ADP 67.9±3.27% (p<0.05), collagen 69.3±3.49% (p<0.01), epinephrine 66.8±3.97%, respectively]. 4) There were no differences in the plasma thromboxane B2 levels between controls (4.6±1.44 pg/ml) and NIDDM patients (8.5+1.95pg/ml), and after exercise, thromboxane B2 was decreased, but not significantly, in NIDDM patients (before exercise; 18.1±5.36pg/ml, after exercise; 11.5±2.58 pg/ml). 5) Duration of diabetes, hemoglobin Ai, and fasting blood sugar did not affect the platelet aggregation. These results indicate that short-term exercise decreases platelet aggregation in NIDDM patients.

당뇨병성 망막증의 위험인자에 관한 고찰

최종상(Jong Sang Choi),장현주(Hyun Ju Jang),안재수(Jae Su An),정동진(Dong Jin Choung),윤재영(Jae Young Yoon),정민영(Min Young Chung),이태희(Tai Hee Lee) 대한내과학회 1991 대한내과학회지 Vol.40 No.4

N/A It is very important to identify the risk factors for diabetic retinopathy because diabetic retinopathy is a major problem for the diabetic patient and represents the commonest cause of acquired blindness in adults. To evaluate the risk factors for diabetic retinopathy, 325 diabetic patients underwent both polaroid fundus photography and fluorescent retinal angiography using a Canon CF-U fundus camera. Clinical characteristics and the laboratory findings of patients with proliferative retinopathy and patients with background retinopathy were compared with diabetic patients with normal retinal findings. The results were as follows: 1) Of the 325 patients, 96 patients (29.5%) had diabetic retinopathy, 90 paitents (27.7%) had background retinopathy, and 6 patients (1.8%) had proliferative retinopathy. 2) In the background diabetic retinopathy group, the duration of diabetes (5.9±4.68 years) was significantly longer than the normal retinal group (3.6±3.80 years) (p < 0.01). 3) The frequency of diabetic retinopathy increased from 22.5% in those with diabetes for less than 5 years to 50.6% in those who have had it for 5 to 10 years, and to 72.2% in those who have had it for more than 10 years (p < 0.01). 4) No significant differences were observed in sex, current age, age at diagnosis, systolic blood pressure, hematocrit, serum cholesterol hemoglobin Alc, fasting blood sugar, and obesity between the diabetics with normal retinal findings and the diabetic retinopathy group. 5) The average diastolic blood pressure of the proliferative retinopathy group (88.3±7.53mmHg) was higher than that of the normal retinal findings (79.0±10.13mmHg) (p<0.05) 6) When the results of fundus photography were compared to fluorescent retinal angiography, the sensitivity and specificity of fundus photography was 66.7% and 93.9%, respectively. 7) An analysis of the distribution of microaneurysms showed microaneurysms were found to occur most frequently in the perimacular area (44.4%), and secondly in the temporal-to-macula area (26.7%). These results suggest that fluorescent retinal angiography was more valuable in detecting early diabetic retinopathy that was missed by fundus camera. The risk factors for diabetic retinopathy were the duration of the diabetes not only in the background but also proliferative retinopathy and diastolic blood pressure in proliferative retinopathy.

당뇨병성 말초신경장애에서의 Vibratory Perception Threshold

윤재영(Jae Young Yoon),정동진(Dong Jin Chung),최종상(Jong Sang Choi),안재수(Jae Su An),장현주(Hyun Ju Jang),정민영(Min Young Chung),이태희(Tae Hee Lee) 대한내과학회 1991 대한내과학회지 Vol.41 No.4

N/A To assess the relation between vibratory perception threshold (VPT) and diabetic neuropathy, we checked beat-to-beat variation test (BBV) and VPT in 67diabetics (24insulin-dependent diabetes mellitus (IDDM), 43 non-insulin dependent diabetes mellitus (NIDDM)) and 35control subjects of similar age, and the following results were obtained. 1) In the control subjects, the VPT value was 7.2at the left 1st metacarpal area and 19.0at the left anterior superior iliac spine. The values in the lower extremities were higher than those of the upper extremities, and there were no differences between the left and right. 2) NIDDM patients had significantly higher VPT values at all sites, especially in the lower extremities, than those of the control subjects (p<0.01) (mean VPT values at the left and right lateral malleolus, medial malleolus, 1st metatarsal, and great toe were 26.8, 24.8, 25.1, 25.7, 20.2, 21.9, 18.9 and 18.3 in diabetics, and 16.5, 17.2, 17.3, 18.8, 14.5, 14.1, 12.1 and 11.0 in the controls, respectively). 3) The VPT values of NIDDM patients with symptoms of peripheral neuropathy were significantly higher in the upper and lower extremities (mean VPT values at the left and right radial and ulnar tubercle in the upper extremities were 14.2, 16.3, 12.2 and 15.8, respectively (p<0.05) and at the left and right lateral malleolus, medial malleolus, 1st metatarsal and great toe in the lower extremities were 31.4, 29.3, 30.1, 30.0, 23.6, 27.2, 22. 5 and 21.7 respectively (p<0.01)) than those of the control and asymptomatic subjects. 4) Among the asymptomatic NIDDM patients (n=16), the VPT values of 5 were higher than those of the others at olecranon, radial tubercle, and ulnar tubercle (p<0.05, respectively). However, the BBV showed no significant differences between them. 5) There were associations of the VPT values with age in the diabetic and control subjects (diabetic; r=0.52, p<0.001, control; r=0.74, p<0.001) and those in the lower extremities in NIDDM patients were associated with duration of diabetes (r=0.49, p<0.001) and age (r=0.43, p<0.01). 6) There were no relations between VPT values and angiographyically comfirmed retinopathy in NIDDM patients. 7) VPT values and BBV in IDDM patients were not significantly different from age matched control subjects (in BBV test; 14.4 in IDDM patients and 12.3 in controls). These results suggest that measurement of VPT is useful aid for early diagnosis of peripheral neuropathy in NIDDM patients, and diabetic peripheral neuropathy could be developed without automonic neuropathy.

당뇨병성신증 조기진단법의 비교 고찰

장현주(Hyun Ju Chang),최종상(Jong Sang Choi),정동진(Dong Jin Jeong),박상선(Sang Seon Park),정민영(Min Young Chung),이태희(Tai Hee Lee) 대한내과학회 1992 대한내과학회지 Vol.43 No.1

N/A Background: As a late complication the diabetic nephropathy is a major cause of death in diabetic patient. For early detection of diabetic nephropathy, the morphologic examination by renal biopsy and the urinary excretion of microalbumin, N-acetyl-p-Dglucosaminidase (NAG), β2-microglobulin (β2-MG), transferrin, leucine aminopeptidase (LAP), kappa light chain, retinol-binding protein and β-galactosidase have been measured. Methods: The 38 NIDDM patients and 21 control subjects were studied and the diabetic patients were divided into three groups according to the results of urinalysis and Micro-Blumintest (group I: no proteinuria in random urine and microalbuminuria negative, n=19; group II: only microalbuminuria positive, n=7; group III: overt proteinuria, n=12). We measured the urinary excretion of NAG (Colorimetric method),β2-MG (EIA) and microalbumin (Micro-Bumintest), and compared with the diagnostic availability of these for early detec- tion of diabetic nephropathy among groups. Results: The urinary concentrations of NAG were 5,0±0.9U/L (mean±SE), 21,l±32,7U/L, 28,8±6.2U/L, and 2.7±0.6 U/L in group I, II, III and control, respectively and the value of group II was significantly higher than that of group I (p <0. 01) and the value of group III was significantly higher than that of group II (p <0. 001). The urinary concentrations of p-MG were 87,1±38,4 p g/L, 143.8±62.2pg/L, 1182,9±724.4pg/L, and 34.3±8,0pg/L in group I, II, III and control, respectively and significant differences among groups were not shown. Conclusion: In addition to the measurement of urinary microalbumin, the urinary excretion of NAG may be useful test for early detection of diabetic nephropathy

Insulin 비의존형 당뇨병환자에서 Insulin 과 Gliclazide 병합요법의 효과에 관한 연구

윤재영(Jae Young Yoon),장현주(Hyun Ju Jang),안재수(Jae Su An),정동진(Dong Jin Chung),최종상(Jong Sang Choi),정민영(Min Young Chung),이태희(Tai Hee Lee) 대한내과학회 1990 대한내과학회지 Vol.39 No.2

N/A This study was performed on the acute effect of gliclazide and insulin combination in non insulin dependant diabetic (NIDDM) patients who had been in secondary failure with oral hypoglycemic agents treatment. Thirty minutes after premedication with 80 mg gliclazide or placebo, 11.25 unit of rapid acting recombinant human insulin were infused through the forearm vein for 45 minutes. Blood sugar measurements were made at 10-minute intervals, whereas serum insulin and C-peptide levels were measured at 30-minute intervals. The results were as follows: 1) There was no significant difference in the basal serum insulin concentration before the insulin infusion after placebo and gliclazide administration. Peak serum insulin concentration was attained 30 minutes after insulin infusion. The values were 312±26 μU/ml after placebo administration and 312±19 μU/ml after gliclazide adminisration. 2) Blood sugar levels of both groups fell to 130 mg/dl one hour after insulin infusion and remained at euglycemic state during the study. 3) Although both showed no difference in the basal C-peptide concentration, the serum C-peptide concentration of the gliclazide group was significantly higher than that of the placebo group. These results indicate that gliclazide combined with insulin may increase endogenous insu1in secretory capacity, even in the presence of secondary failure of oral hypoglycemic agents.

픽의 제 1법칙을 사용한 발한량 측정 방법에 관한 연구

강민호(Min-Ho Kang),박준호(Jun-Ho Park),정동진(Dong-Jin Jung),조종만(Jong-Man Cho) 대한전기학회 2015 대한전기학회 학술대회 논문집 Vol.2015 No.2

본 연구에서는 땀의 발한량을 실시간으로 측정하기 위한 방법을 확인한다. 땀의 주 성분인 수분이 증발하는 것을 측정하기 위해 Fick"s first law of diffusion을 중심으로 다수의 검증된 이론을 사용하였다. 내경 30mm의 아크릴 원통 내부에 2개의 온습도센서를 사용하여 두 지점의 온도 및 상대습도를 측정하였으며, 이를 기준으로 수분의 확산량을 계산하였다. 계산값의 비교를 위해 수분의 실제 증발량을 마이크로밸런스를 사용하여 측정하였다. 실험은 마이크로밸런스 측정값을 기준으로 16.67~123.33 ㎍/min 범위의 증발량을 측정하였다. 총 6개의 그룹에서 측정하였으며, 각 그룹별 5회의 실험을 반복하여 평균값을 비교하였다. 측정값대 계산값의 비율은 0.97~1.10로 나타났으며, 따라서 이 방법은 유효하다 판단된다.

특허권 강화는 기술혁신을 촉진하는가? : 한국의 특허법 개혁을 중심으로 Evidence From the Korean Patent Law Reforms

徐煥周,鄭東進,宋鍾國 한국국제경제학회 2004 국제경제연구 Vol.10 No.2

1970년대 말 이후 취해진 미국의 일련의 특허권 개혁과 1994년에 체결된 TRIPS협약을 계기로 특허권 강화와 기술혁신간의 상관관계에 대한 수많은 실증연구가 1990년대 들어 행하여지고 있다. 그러나 최근의 실증연구결과들은 특허권강화가 기술혁신을 촉진하는 유효한 수단인가에 대해서 명확한 결론을 내리지 못하고 있어, '특허의 역설(Patent paradox)'이라 불리고 있다. 본 연구는 우리나라의 특허 및 연구개발 지출 자료를 활용하여 특허권 강화(특허법개혁)가 기술혁신활동에 유효한 인센티브로 작용하는 지를 살펴보았다. 분석결과 1980년대 말의 특허법 7차 개정과 1990년대 중반의 11차 개정이 연구개발 지출과 특허출원건수로 측정한 기술혁신활동에 긍정적으로 작용하였음을 발견하였다. 그러나 우리의 추정방법이 제도개혁의 직접적인 영향만을 추정하는 것이 아니라 여타의 거시적 충격까지 포함할 가능성이 있기 때문에 조심스러운 해석을 요한다. By influencing the incentives to innovate, the strengthening of patents may affect economic growth in important way. An important question for many countries is whether patent law reforms induce more innovation. This paper examines the role of patents in innovation, utilizing Korean data on patent applications, expenditure of R&D, sales and concentration ratio. The evidence suggests that the strengthening of patents was a significant determinant of innovation in Korea. However, in our estimations, we do not completely eliminate the effects of other macro shocks. Therefore, we interpretate our results as representing an "upper bound" of Korean firms' responses to patent law reforms.

한국인 인슐린비의존형 당뇨병환자에서 엔지오텐신 1-전환효소 유전자의 다형성과 당뇨병성 만성합병증 및 관상동맥질환과의 관계

정민영,천남일,이창훈,조동혁,강호철,정동진,정명호,강정채,박종태,양승원 全南大醫大 2001 전남의대학술지 Vol.37 No.3