Infliximab으로 호전된 장관 증상없이 발생한 구강-안면 크론병

정보용 ( Bo Yong Jung ),이석호 ( Suck Ho Lee ),정승규 ( Seung Kyu Chung ),이창균 ( Chang Kyun Lee1 ),이태훈 ( Tae Hoon Lee ),정일권 ( Il Kwun Chung ),김선주 ( Sun Joo Kim ),조현득 ( Hyun Deuk Cho ) 대한소화기학회 2012 대한소화기학회지 Vol.59 No.6

Crohn`s disease is a chronic inflammatory bowel disease that can involve the whole gastrointestinal tract. The orofacial manifestation of Crohn`s disease, which is rare, can develop irrespective of intestinal involvement. These orofacial lesions are often misdiagnosed as simple oral ulcers. Corticosteroids are the mainstay of therapy for orofacial Crohn`s disease. However, infliximab, the chimeric monoclonal antibody to tumor necrosis factor-α, is now considered as a primary treatment because of the disease`s relatively high rate of steroid resistance. We present a case of deep oral ulcer and periorbital swelling in a 65-year-old woman. She was diagnosed with intestinal Crohn`s disease 7 years ago, which was in remission after treatment with an immunosuppressive agent (azathioprine). The patient was given the diagnosed with orofacial Crohn`s disease and successfully treated with infliximab. (Korean J Gastroenterol 2012;59:437-440)

우심방을 침범한 거대 비호지킨씨 림프종 1예

강상범,진승원,이은경,박용현,최용호,김용주,박준철,김재형,홍순조,최규보,권종범,원용순,박건,이은희 대한순환기학회 2000 Korean Circulation Journal Vol.30 No.4

정상 관동맥을 가진 심장 점액종 환자에서 발생한 급성 심근 경색증 1예

이정민,이현승,전은정,윤호중,정욱성,오용석,김철민,김재형,최규보,홍순조,이교영,심상인 대한순환기학회 1998 Korean Circulation Journal Vol.28 No.9

漢詩 用事에 나타난 朝鮮時代 樓亭 經營意識에 關한 硏究

李元浩,金龍基,사공영보(보자 한문지원안됨),崔鍾熙 한국전통조경학회 2003 한국전통조경학회지 Vol.21 No.4

This study was carried out to recognize awareness of the scholars in Chosun Dynasty on the pavilion management through the philological literature study of Young-Sa (用事:A Chinese poem, Allusion). The 18 pavilions were selected as subjects with following selection criteria. - Being extant of poetry and prose in the pavilion among 100 pavilion candidates, quoted from Nujungjeyoung (Published by Gwangju-City in 1992). - Built in Chosun Dynasty. Focusing on contents analysis, the words that are categorized in allusion were abstracted and then comparative analysis for meaning of the word and frequency of appearance with source were carried out. The findings are as follows ; 1) It is of loyalty and filial piety phenomenon. A man of high frequency in pavilion allusion is the person who has contributed to loyalty and filial piety. It is believed that moral of loyalty and filial piety were provided through referring to the Chinese ancient history. One of examples is that naming pavilion meaning of place for composing poem of pledging loyalty to the king cherishes the memory of late fathers. 2) It is building temperament/character. Expressed an attitude of building temperament/character in pavilion through alluded men and ancient history. Mainly JUJA, Confucius and MANGJA were alluded. The expression of willingness in building temperament/character is reflected in poems by allusion of delegated men. 3) It is ethics and seclusion phenomenon. The origin of the ethics phenomenon in Chosun dynasty orginated from the outside, but its formation and progress were influenced by the Honam district (the southwestern part of Korea). The foundation of such progress was pavilions and pavilion literature, surrounding Lake Gwangju. 4) Seeking for hypothetical scene. Alluded Chinese famous names of places were familiar with oral tradition or reading and assumed to be hypothetical scenes of pavilion builders. The meaning of alluded scenes materialized hypothetical scenes in the individual mental image that is learnt from ancient times. That is, the aspiration of the builders for Utopia is reflected into hypothetical scenes. This study analyzes immanent meaning of the words, expressed by allusion in poetry based on sources. Lack of structural and semantic study of Chinese poems is the limit of the landscape architectural approach and a supplement theoretical study of Chinese poems is needed.

신경병증성 통증 쥐 모델에서 전신적으로 투여한 Ketamine의 선행진통 효과

이보령,김진윤,박선규,구길회,우영철,정용훈,백종화,박정원,이인구 중앙대학교 의과대학 의과학연구소 2003 中央醫大誌 Vol.28 No.3

이행성 협심증 환자에서 운동부하 심전도 검사

이정우,박형서,박용규,노상필,이유선,정승현,김보영,이재환,최시완,정진옥,성인환 충남대학교 의과대학 의학연구소 2003 충남의대잡지 Vol.30 No.1

목적 : 관상동맥의 경련에 의한 이형성 협심증환자에 있어서 운동부하 심전도 검사의 결과는 매우 다양하다. 이에 저자들은 충남대학교병원 순환기내과에서 관상동맥조영술상 이형성 협심증으로 확진된 환자를 대상으로 운동부하 심전도 검사를 시행하여 이에 대한 결과를 연구하였다. 방법 : 1995년 1월부터 2002년 3월까지 흉통을 주소로 충남대학교병원 순환기 내과에 입원하여 관상동맥조영술을 시행하여 관상동맥의 내경이 50% 미만의 협착이 있고, 에르고노빈(ergonovine) 유발검사도 이형성 협심증으로 진단을 받은 233명중 운동부하 심전도 검사를 시행 받은 183명의 환자를 연구 대상으로 하였다. 운동부하 심전도 검사 결과의 판독시 발생할 수 있는 오류를 줄이기 위해서 운동부하 심전도 검사를 시행하기전 심전도상 ST분절의 상승(5예)이나 하강(8예)이 있는 경우 EH한 T파의 역위(19예)가 있는 32명의 환자를 제외한 총 151명의 환자를 대상으로 하였다. 운동부하는 Marquette사의 case 15 답차를 이용하였고, Bruce protocol에 따라 증상이 나타날 때까지 최대로 실시하였으며 각 stage 및 운동후의 혈압을 측정하고 12 유도 심전도를 기록하였다. 결과 : 1) 임상적 특성 - 내원시 임상 상은 안정형 협심증이 39예(25.8%), 불안정형 협심증이 103예(68.2%), 심근경색증이 9예(6.0%)이었다. 운동부하 심전도 검사 결과 양성 군과 음성군간에 있어서 당뇨병, 고혈압, 비만도, 총 혈청콜레스테롤치, 현재의 흡연 여부, 병력상 운동시 흉통의 유무, 내원시 임상적 진단, 협착의 정도, 연축의 수 등을 조사하였는 바 어떠한 인자들도 유의한 차이를 발견할 수 없었다. 2) 운동부하 심전도 검사 - 운동부하 심전도 검사를 시행 받은 151명의 환자중 음성인 경우는 134예(88.8%)이었고, 양성인 경우는 17예(11.2%)이었다. 양성 소견을 보인 환자들중 ST 분절의 상승이 4예(2.6%), ST 분절의 하강이 13예(8.6%)이었다. 3) 관상동맥조영술 - 관상동맥조영술상에서 혈관 경력 위치는 우관상동맥이 70예(46.1%), 좌전하동맥이 44예(28.9%), 좌회선동맥이 17예(11.2%)의 순으로 나타났다. 운동부하 심전도 검사상 ST 분절의 상승이 있었던 예중 Ⅱ, Ⅲ, aVF에서 ST 분절의 상승이 있었던 1예는 관상 동맥조영술상 우관상동맥에서 경련이 발생하였고, V2-V4에서 ST 분절의 상승이 있었던 2예중 관상동맥조영술상에도 좌전하행동맥에서 경련이 나타난 예는 1예이었으며 다른 1예는 좌회선동맥에서 경련이 나타났고, V5-V6에서 ST 분절의 상승이 있었던 1예는 관상동맥조영술상에도 좌회선동맥에서 경련이 나타났다. 운동부하 심전도 검사상 V5 또는 V6에서 ST 분절의 하강이 있엇던 13예중 6예(46.1%)는 관상동맥조영술상 우관상동맥에서 경련이 발생하였고, 3예(23.1%)는 좌전하행동맥에서, 1예(7.7%)는 좌회선동맥에서, 나머지 3예(23.1%)는 2개의 혈관이나 기타 분지에서 경련이 발생하였다. 결론 : 1) 이형성 협심증 환자는 운동부하 심전도 검사에서 11.2%의 양성소견을 보였다. 이중 ST 분절의 상승은 2.6%이었고, ST 분절의 하강은 8.6%이었다. 2) 이형성 환자중 운동부하 심전도 검사를 실시하여 음성을 보이는 경우 다혈관 관상동맥질환이기 보다는 이형성 협심증일 가능성이 더 높다고 예측할 수 있을 것으로 생각된다. 3) 이형성 협심증 환자중 운동부하 심전도 검사를 실시하여 ST 분절의 상승을 보이는 경우 다혈관 관상동맥질환이기 보다는 이형성 협심증일 가능성이 더 높다고 예측할 수 있을 것으로 생각된다. 4) 운동부하 심전도 검사 결과에 대한 당뇨병, 고혈압, 비만도, 총 혈청콜레스테롤치, 현재의 흡연여부, 병력상 운동시 흉통의 유무, 내원시 임상적 진단, 협착의 정도 등 어떠한 인자들도 3그룹(ST 분절의 상승, ST 분절의 하강, 음성)간에 유의한 차이를 발견할 수 없었다. 5) ST 분절의 상승 부위와 관상동맥조영술상 관상동맥의 연축이 일어나는 혈관과의 상관관계는 매우 높았다. No reports in the literature describe the results of exercise testings in a large number of patients with pure variant angina(coronary stenosis <50%) in Korea. In this report, We present the results of treadmil exercise testing in 151 patients with variant angina. 151 patients with angiographically proven coronary artery spasm underwent a treadmil exercise test. The clinical characteristics of variant angina patients classified according to ST-segment response to exercise were analyzed. Of 151 patients underwent a treadmil exercise test, negative result was seen in 134 patients(88.8%) and positive result was in 17 patients(11.2%). Of 17 patients saw positive result, exercise-induced ST segment elevation was present in 4 patients(2.6%) and ST segment depression was seen in 13 patients(8.6%). There was not a significant relationship between the ST segment response to exercise and the clinical variables(diabetes, hypertension, obesity, total cholesterol, current smoking, effort angina, clinical diagnosis, and degree of stenosis) assessed. Of 4 patients with ST segment elevation in treadmil exercise test, 1 patient with ST segment elevation in Ⅰ,Ⅲ,aVF had spasm in right coronary artery(100%) on coronary angiography, of 2 patients in V2-V4 had spasm in left anterior descending coronary artery in 1 patient(50%) and 1 patient in V5-V6 had spasm in left circumflex artery(100%). Positive treadmil exercise test was present in 11.2% of variant angina patient. If we have negative treadmil exercise result in patients with clinical manifestation of unstable angina at admission, we may have a suspicion of variant angina rather than multi-vessel disease. If we have exercise-induced ST segment elevation in patients with clinical manifestation of unstable angina at admission, we have a suspicion of variant angina rather than multi-vessel disease. Our result suggests that the correlation between the site of the ST segment elevation and the artery involved is quite good.

한글대장경 검색 시스템

이금석,이용규,홍영식,한태식 동국대학교 전자불전연구소 2002 전자불전 Vol.4 No.-

한글대장경의 전산화 및 검색 시스템 개발은 세계에 우리 문화의 우수성을 널리 알리고, 우리 문화유산에 대한 국민적 관심을 높이며 해당 분야에 대한 효과적인 연구를 지원하기 위해 반드시 필요하다. 한글대장경은 고려대장경의 번역본으로 주로 한글로 기록되어 있지만, 원문의 이해를 돕기 위해서 다양한 한자가 사용되고 있다. 이러한 한자들은 본자(本字)와 뜻은 같지만 모양이 틀린 이체자(異體字)및 오자(誤字)나 탈자(脫字)로 간주되는 파자(破字) 등을 포함하고 있으므로 입력이나 저장 뿐 아니라 검색 관점에서도 여러 가지 문제점을 갖는다. 또한 인터넷이 널리 보급되면서 인터넷을 통한 문헌 검색이 증가하였지만 기존의 문헌 검색 시스템은 용어 검색, 색인 검색 등과 같은 단순한 검색만을 지원하기 때문에 사용자의 다양한 검색 요구를 충족시키기가 어려웠다. 본 연구에서는 한글대장경의 효과적인 입력과 저장을 위해 유니코드(unicode)를 사용하였고, 효율적인 검색을 위해 문서 구조를 XML로 정의하였으며, 결과내 검색과 히스토리 검색 등과 같은 다양한 검색 방법을 지원하는 웹 기반 한글 대장경 검색 시스템을 개발하였다.

십이지장과 대장을 동시에 침범한 결핵 1예

이만재,박치영,곽재정,유보열,기장도,박찬국,김만우,김정용 조선대학교 1995 The Medical Journal of Chosun University Vol.20 No.1

Tuberculosis of duodenum is so rare and is usually secondary to pulmonary or intestinal tuberculosis . It is difficult to diagnose duodenal tuberculosis in clinical and radiologic findings due to its non-specific symptoms and inconsistent lesion. The diagnosis was made on the basis of the histological study of the endoscopic biopsy and resected surgical specimen. so we report a case of tuberculosis of duodenal bulb and of ascending colon with, the brief review of the literatures.

金忠壯公遺事를 통해 본 光州 楓巖亭 주변의 景觀特性에 關한 硏究

李元浩,金龍基,사공영보,崔鍾熙 한국전통조경학회 2003 한국전통조경학회지 Vol.21 No.2

This study was carried out to recognize the distinctive quality of the scene around 'PUNGAMGEONG'(楓巖亭) through appreciation in its building, location and architectural view of the space based on 'KIM CHUNG JANGGONGYUSA'(金忠壯公遺事), published during the reign of 'JEONGCHO'(正祖) in 'CHOSON'(朝鮮) dynasty. The study was conducted by contents analysis of 'KIMCHUNGJANGGONGYUSA' and other related paleography as prime as well as verification of the location and architectural view of the space through field survey with topographical chart(1/5,000, 1/25,000) and survey drawing. Analysis method fell into the background of building and location space structure as well as a comparative analysis of the literature with interview with local authority staffs and descendants. The results are as followings; 1) The background of the Pungamjeong's building is influenced by KIMDEOKBO(金德普)'s amusement(good landscape gusto) in fine view and moralistic view in nature as well as seclusion and recuperation with misfortune of his family. 2) Location of the Pungamjeong is suitable for seclusion with graceful natural scenes as well as adjacency with the ancestral burial ground for memorial service. 3) The space structure of the Pungamjeong for literature analysis consists of the space for production in bamboo grove to stream surrounding, the space for study and appreciation in pavilion and the space of fairyland in left side of locks. 4) The Pungamjeong stands with a pavilion of two rooms reconstructed in the tile house, and the vegetation appears in the literature of Pinus dansiflora S. et Z, Prunus mume S. et Z, Phyllostachys nigra Munro, Acer pseudosieboldianum Komar and Prunus persica (L.) Batsch forming identifying marks, but Pinus densiflora S. et Z, Phyllostachys nigra Munro, Abies holophylla Maxim, Acer pseudosieboldianum Komar, Carpinus laxiflora Blume, Zelkova serrata Makino, Prunus sargentii Rehder, Fraxinus rhynchophylla Hance, Quercus monglica Fisch and Rhododendron mucronulatu Turcz are found recently. Also, wild natural rocks in the Pungamjeong are one of its valuable parts representing personality of folk belief to the local residents. It is recommended that further embodied and substantive studies should be followed with the systematic literature analysis and field survey for restoration and maintenance of the place since this study comes from the literature analysis only.

우리나라의 行政上의 損害賠償制度에 관한 硏究

李輔泳 광주보건대학 1982 論文集 Vol.7 No.-

When private individuals are suffered damage by a nation's and a private institution's operation without private individual's blame, it is a matter of course that, in view of the principle of justice and equity, a nation and a public institution should pay for damages. This dissertation contains following contents. That is to say, the administrative compensation for damages is that, in such a case that, due to an official's illegal act and a fault of undertaking and equipment which a nation and a public institution manage and run, private individuals are suffered damages, a nation and a public institution should pay for damages. Such an adiministrative compensation for damages is based on modern individualistic thought and is on the basis of individual and morals ense of responsibility. But the system of compensation for damages is different from that of indemnity for losses which grow into the realization of fundamental principle,-social and balanced responsibility, -on the basis of collectivistic thought. But in recent time, under the close connection with the operation of a nation and a public institution, not only do both systems pay for damages occurring in private individuals, but also is there growing tendency that they are harmonized with grand scale of enterprise and magnification of national function. In our country, both systems are devided in the positive law.