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RISS 인기검색어
- 검색키워드
- 저자 : (Raymond H . Dean) (검색결과 3 건)
- 무료
- 기관 내 무료
- 유료
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IL10 and TNF variants and risk of non-Hodgkin lymphoma among three Asian populations
Hosgood III, H. Dean,Au, Wing-Yan,Kim, Hee Nam,Liu, Jie,Hu, Wei,Tse, Jovic,Song, Bao,Wong, Kit-fai,Lee, Je-Jung,Chanock, Stephen J.,Siu, L. P.,Purdue, Mark P.,Shin, Min-ho,Yu, Jinming,Liang, Raymond,K Springer-Verlag 2013 International journal of hematology Vol.97 No.6
<P>Genetic variation in immune-related genes, such as IL10 and TNF, have been associated with the development of non-Hodgkin lymphoma (NHL) in Caucasian populations. To test the hypothesis that IL10 and TNF polymorphisms may be associated with NHL risk in Asian populations, we genotyped 20 single nucleotide polymorphisms (SNPs) within the IL10 and TNF/LTA loci in three independent case-control studies (2635 cases and 4234 controls). IL10 rs1800871, rs1800872, and rs1800896 were genotyped in all three studies, while 5 of the remaining SNPs were genotyped in two studies, and 12 in a single study. IL10 rs1800896 was associated with B cell lymphoma [per-allele odds ratio (OR)?=?1.25, 95?% confidence interval (CI)?1.08-1.45; p trend?=?0.003], specifically diffuse large B cell lymphoma (DLBCL) (per-allele OR?=?1.29, 95?% CI?1.08-1.53; p trend?=?0.004), as well as T cell lymphoma (per-allele OR?=?1.44, 95?% CI?1.13-1.82; p trend?=?0.003). TNF rs1800629, which was genotyped in only two of our studies, was also associated with B cell lymphoma (per-allele OR?=?0.77, 95?% CI?0.64-0.91; p trend?=?0.003), specifically DLBCL (per-allele OR?=?0.69, 95?% CI?0.55-0.86; p trend?=?0.001). Our findings suggest that genetic variation in IL10 and TNF may also play a role in lymphomagenesis in Asian populations.</P>
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소프트웨어공학 : 소프트웨어 신뢰도의 평가와 예측을 위한 베이지안 알고리즘
박만곤(Park Man Gon),(Raymond H . Dean) 한국정보처리학회 1994 정보처리학회논문지 Vol.1 No.1
This paper proposes two Bayes estimators and their evaluation algorithms of the software reliability at the end testing stage in the Smith's Bayesian software reliability growth model under the beta prior distribution BE(a,b), which is more general than uniform distribution, as a class of prior information. We consider both a squared- error loss function and the Harris loss function in the Bayesian estimation procedures. We also compare the MSE performances of the Bayes estimators and their algorithms of software reliability under the Harris loss functions is more efficient than other estimators in terms of the MSE performances as a is larger and b is smaller, and that the Bayes estimators using the beta prior distribution as a conjugate prior is better than the Bayes estimators under the uniform prior distribution as a noninformative prior when a>b.
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Novel Repair of Clamshell Thoracotomy Sternal Dehiscence after Lung Transplant: A Case Report
John O. Barron,Nethra Jain,Mujtaba Mubashir,Haytham Elgharably,Daniel P. Raymond,Dean P. Schraufnagel 대한심장혈관흉부외과학회 2024 Journal of Chest Surgery (J Chest Surg) Vol.57 No.2
Bilateral transverse thoracosternotomy, or “clamshell” thoracotomy, can be complicated by dehiscence. A 65-year-old male underwent lung transplantation via clamshell thoracotomy, with subsequent sternal dehiscence on postoperative day 11. Upon repair, the previous sternal wires had pulled through, so a Sternal Talon connected to a Recon Talon was utilized to re-approximate the inferior sternum. On follow-up at 3 months, the patient recovered well. Use of the Sternal Talon provides an effective technique for repairing transverse sternal dehiscence.
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