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Precise asymptotics in the law of the logarithm for the rescaled range statistic
Zheng-Yan Lin,Tian-Xiao Pang,황교신 한국통계학회 2013 Journal of the Korean Statistical Society Vol.42 No.2
For a sequence of i.i.d. zero mean random variables belonging to the domain of attraction of the normal law, two results concerning the rescaled range statistic are investigated in this paper. More specifically, we obtain precise asymptotics in the law of the logarithm related to complete convergence and a.s. convergence under some mild conditions.
Zheng Lin Zhao,Bong Hyo Lee,Feng Lin,YanQin Guo,Yi Yan Wu,Sang Mi Park,Sunghyeon In,Sang Chan Kim,Chae Ha Yang,Rong Jie Zhao 사단법인약침학회 2014 Journal of Acupuncture & Meridian Studies Vol.7 No.5
The current study investigated the effects of acupuncture at Zu-San-Li (ST36) on the hypothalamicepituitaryeadrenalaxis during ethanol withdrawal in rats. Rats were intraperitoneallytreated with 3 g/kg/day of ethanol or saline for 28 days. Following 24 hours ofethanol withdrawal, acupuncture was applied at bilateral ST36 points or non-acupoints(tail) for 1 minute. Plasma levels of corticosterone (CORT) and adrenocorticotropic hormone(ACTH) were measured by radioimmunoassay (RIA), and the corticotropin-releasingfactor (CRF) protein levels in the paraventricular nucleus of the hypothalamus were alsoexamined by RIA 20 minutes after the acupuncture treatment. RIA showed significantlyincreased plasma levels of CORT and ACTH in the ethanol-withdrawn rats compared withthe saline-treated rats, which were inhibited significantly by the acupuncture at the acupointST36 but not at the non-acupoint. Additionally, ethanol withdrawal promoted CRFprotein expressions in the paraventricular nucleus of the hypothalamus, which were alsoblocked by the acupuncture at ST36. These findings suggest that acupuncture at the specific acupoint ST36 can inhibit ethanol withdrawal-induced hyperactivation of hypothalamicepituitaryeadrenalaxis, and it may be mediated via the modulation of hypothalamicCRF.
Synchronization for IR-UWB System Using a Switching Phase Detector-Based Impulse Phase-Locked Loop
Lin Zheng,Zhenghong Liu,Mei Wang 한국전자통신연구원 2012 ETRI Journal Vol.34 No.2
Conventional synchronization algorithms for impulse radio require high-speed sampling and a precise local clock. Here, a phase-locked loop (PLL) scheme is introduced to acquire and track periodical impulses. The proposed impulse PLL (iPLL) is analyzed under an ideal Gaussian noise channel and multipath environment. The timing synchronization can be recovered directly from the locked frequency and phase. To make full use of the high harmonics of the received impulses efficiently in synchronization, the switching phase detector is applied in iPLL. It is capable of obtaining higher loop gain without a rise in timing errors. In different environments, simulations verify our analysis and show about one-tenth of the root mean square errors of conventional impulse synchronizations. The developed iPLL prototype applied in a high-speed ultra-wideband transceiver shows its feasibility, low complexity, and high precision.
The crosstalk between bacteria and host autophagy: host defense or bacteria offense
Zheng Lin,Wei Fang,Li Guolin 한국미생물학회 2022 The journal of microbiology Vol.60 No.5
Xenophagy is a specific selective autophagy for the elimination of intracellular bacteria. Current evidence suggests that the processes for host autophagy system to recognize and eliminate invading bacteria are complex, and vary according to different pathogens. Although both ubiquitin-dependent and ubiquitin-independent autophagy exist in host to defense invading bacteria, successful pathogens have evolved diverse strategies to escape from or paralyze host autophagy system. In this review, we discuss the mechanisms of host autophagy system to recognize and eliminate intracellular pathogens and the mechanisms of different pathogens to escape from or paralyze host autophagy system, with a particular focus on the most extensively studied bacteria.
Zheng Lin Zhao,김상찬,Jie Zhang,Hong Feng Liu,이봉효,장은영,이철원,조일제,안원근,양재하,김영우,Rong Jie Zhao,Yi Yan Wu 사단법인약침학회 2016 Journal of Acupuncture & Meridian Studies Vol.9 No.1
A previous study demonstrated that acupuncture at ST36 (Zu-San-Li) attenuates ethanol withdrawal (EW)-induced hyperactivation of the hypothalamic–pituitary–adrenal axis in rats. The current study investigated the involvement of hypothalamic norepinephrine (NE) in that process. Rats were intraperitoneally treated with 3 g/kg/d of ethanol or saline for 28 days. After 24 hours of EW, acupuncture was applied to rats at bilateral ST36 points or at nonacupoints (tail) for 1 minute. A high-performance liquid chromatography analysis showed that EW significantly increased both the NE and the 3-methoxy-4-hydroxy-phenylglycol (MHPG) levels in the hypothalamic paraventricular nucleus (PVN). Western blot analysis also revealed that EW markedly elevated the phosphorylation rates of tyrosine hydroxylase (TH), but spared TH protein expression in the PVN. However, acupuncture at ST36, but not at nonacupoints, greatly inhibited the increase in the hypothalamic NE, MHPG, and phosphorylation rates of TH. Additionally, postacupuncture infusion of NE into the PVN significantly attenuated the inhibitory effects of acupuncture at ST36 on the oversecretion of plasma corticosterone during EW. These results suggest that acupuncture at ST36 inhibits EW-induced hyperactivation of the hypothalamic NEergic system to produce therapeutic effects on the hypothalamic–pituitary–adrenal axis.
Research on the Development Efficiency of Tourism in the Non-Pearl River Delta of Guangdong
Lin, Jia-Zheng,Kim, Hyung-Ho The International Promotion Agency of Culture Tech 2021 International Journal of Advanced Culture Technolo Vol.9 No.3
On February 18, 2019, the Chinese government officially released the Outline of the Development Plan for the Guangdong-Hong Kong-Macao Greater Bay Area, which will lead the country in a new round of reform and opening-up. The Greater Bay Area will become a dynamic world-class city cluster, an international scientific and technological innovation center with global influence, an important support for the development of the "One Belt And One Road", a demonstration area for in-depth cooperation between the mainland and Hong Kong and Macao, and a high-quality living area for living, working and traveling. Non-Pearl River Delta(Non-PRD) cities in Guangdong Province are adjacent to the Guangdong-Hong Kong-Macao Greater Bay Area, so it is of practical significance to promote the high-quality development of urban tourism from an international perspective. Based on the panel data released in Guangdong Yearbook 2019, this paper uses the envelopment data analysis (DEA) method to explore ways to promote the high-quality tourism development of Non-PRD cities in Guangdong Province based on the perspective of international development.
Zheng, Shan,Song, Qing-Kun,Zhao, Lin,Huang, Rong,Sun, Li,Li, Jing,Fan, Jin-Hu,Zhang, Bao-Ning,Yang, Hong-Jian,Xu, Feng,Zhang, Bin,Qiao, You-Lin Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.5
The aim of this study was to detail characteristics of mammary Paget's disease (PD) representing the whole population in China. A total of 4211 female breast cancer inpatients at seven tertiary hospitals from seven representative geographical regions of China were collected randomly during 1999 to 2008. Data for demography, risk factors, diagnostic imaging test, physical examination and pathologic characters were surveyed and biomarker status was tested by immunohistochemistry. The differences of demography and risk factors between PD with breast cancer and other lesions were compared using Chi-square test or t-test, with attention to physical examination and pathological characters. The percentage of PD was 1.6% (68/4211) in all breast cancers. The mean age at diagnosis was 48.1, and 63.2% (43/68) patients were premenopausal. There is no difference in demography and risk factors between PD with breast cancer and other breast cancer (P > 0.05). The main pattern of PD in physical exam and pathologic pattern were patients presenting with a palpable mass in breast (65/68, 95.6%) and PD with underlying invasive cancer (82.4%, 56/68) respectively. The rate of multifocal disease was 7.4% (5/68). PD with invasive breast cancer showed larger tumor size, more multifocal disease, lower ER and PR expression and higher HER2 overexpression than those in other invasive breast cancer (P < 0.05). These results suggested that PD in China is a concomitant disease of breast cancer, and that PD with underlying invasive cancer has more multiple foci and more aggressive behavior compared with other breast invasive cancer. We address the urgent needs for establishing diagnostic and therapeutic guidelines for mammary PD in China.