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      • 한국인 상악 제1대구치 치근의 면적 및 해부학적 구조에 관한 연구 : 치주질환의 병인론과 치료에 있어서 임상적 중요성 Clinical Significance in Pathogenesis and Treatment of Periodontal Disease

        허익,권영혁,이만섭 慶熙大學校 齒科大學 1989 慶熙齒大論文集 Vol.11 No.-

        The thirty-three maxillary first molars, which were extracted because of the severe periodontal disease, were cross sectioned every 1.5 millimeter from the Cementoenamel junction to the apex, and each section was photographed, projected and measured with a calibrated Digital Curvi-Meter (Corn Curve-8, Japan). The root surface area (RSA), percentage of' the RSA, and the linear variation of the RSA were calibrated for each 1.5mm section: The location of root separation was determined and the length of roots were calculated separately. The results were as follows: 1. The mean length of the roots were 11.52mm for the palatal root, 1 1.28mm for the mesiobuccal root, and 10.68mm for the disobuccal root. The distobuccal root was shortest among the three roots. 2. The mean distance from the Cementoenamel junction to the point at which the roots separate from the root trunk was 4.57mm for the mesiobuccal root and 4.66mm for the distobuccal root. The mesiobuccal root separation was more coronal than the distobuccal root separation but the differences were not significant. 3. The mean root surface area was 88.44mm2 for the mesiobuccal root, 80.14mm2 for the palatal root, and 58.87mm2 for the disobuccal root. The mean mesiobuccal root surface area was wider than the mean palatal root surface area (p < 0.05). 4. The mean surface area of the root trunk was 155.67mm2 and averaged 40.63% of the total root surface area. It was wider than the mean surface area of each roots. 5. The coronal one-half of the root length accounted for approximately 60% of the total root surface area.

      • KCI등재후보

        Implant Placement in Posterior Maxilla Using Modified Lateral Approach: Case Reports

        홍지연,Yeek Herr,정종혁,신승일,임현창,신승윤 대한구강악안면임플란트학회 2017 대한구강악안면임프란트학회지 Vol.21 No.3

        Conventional osteotome-mediated transalveolar approach might bring out patient’s discomfort related to the malleting and unexpected sinus membrane perforation could be overlooked due to its blindness in access. A modified lateral approach, so call hybrid technique, introduced by Jung et al. utilized a minimized linear shaped osteotomy at the lateral wall to provide visual and instrumental access while elevating the sinus floor with transalveolar approach. Through the linear osteotomy, the Schneiderian membrane was detached limitedly in the internal surface of the floor prior to the drill penetration into the sinus and lifting with the hydraulic plug. Two clinical cases that used hybrid technique for the sinus floor elevation spontaneously with multiple implant placements were shown in the present reports. Preoperative remaining bone height ranged from 5 mm to 7 mm and 10 mm length of implants were installed with the vertical bone augmentation of 5~6 mm, which maintained through the follow-up period of 4 and 6 years. None of the cases were involved with the membrane perforation. From the clinical results, hybrid technique was considered to be an effective and noninvasive procedure for sinus floor elevation with spontaneous implant placement in atrophied posterior maxilla.

      • 배양골세포 이식이 치조골재생에 미치는 영향

        정순준,허익,박준봉,이만섭,권영혁 慶熙大學校 齒科大學 1995 慶熙齒大論文集 Vol.17 No.2

        This study was performed to estimate the effects of cultured bone cell inoculated on porous type hydroxyaptite for the regeneration of the artificial alveolar bone defect. In this experiment 3 beagle dogs were used, and each of them were divided into right and left mandible. Every surgical intervention were performed under the general anesthesia by using with intravenous injection of Pentobarbital sodium (30mg/Kg). To reduce the gingival bleeding during surgery, operative site was injected with Lidocaine hydrochloride (1:80,000 Epinephrine) as local anesthesia. After surgery experimental animal were feeded with soft diet(Mighty dog, Frisies Co., U.S.A.) for 1 weeks to avoid irritaion to soft tissue by food. 2 months before surgery both side of mandibular 1st premolar were extracted and bone chips from mandibular body were obtained from all animals. Bone cells were cultured from bone chips obtained from mandible with Dulbecco's Modified Essential Medium contained with 10% Fetal Bovine Serum under the conventional conditions. Porous type hydroxyapatite were immerse into the high concentrated cell suspension solution, and put 4 hours for attachment the cells on the surface of hydroxyapatite. Graft material were inserted on the artificial bone defect after 3 days of culture. Before insertion of cell-inoculated graft material, scanning electronic microscopic observation were performed to confirm the attachment and spreading of cell on the hydroxyapatite surface. 3 artificial bone defects were made with bone trephine drill on Abe both side of mandible of the experimental animal. First defect was designed without insertion of graft material as negative control, second was filled with porous replaniineform hydroxyapatite inoculated with cultured bone marrow cells as expermiental site, and third was filled with graft materials only as positive control. The size of every artificial bone defect was 3 mm in diameter and 3 mm in depth. After the every surgical intervention of animals, oral hygiene program were performed with 0.1% chlorhexidine digluconate. All of the animals were sacrificed at 2, 4, 6 weeks after surgery. For obtaining histological section, tissus were fixed in 2.5% Glutaldehyde and decalcified with Planko-Rycho Solution for 72 hr. Tissue embeding was performed in paraffin and cut parallel to the surface of mandibular body. Section in Bum thickness of tissue was done and stained with Hematoxylin-Eosin. All the specimens were observed under the light microscopy. The following results were obtained. 1. In the case of control site which has no graft material, less inflammatory cell infiltration and rapid new bone forming tendency were revealed compared with experimental groups. But bone surface were observed depression pattern on defect area because of soft tissue invasion into the artificial bone defect during the experimental period. 2. In the porous hydroxyapatite only group, inflammatory cell infiltration was prominet and dense connective tissue were encapsulated around grafted materials. osteoblastic activity in the early stage after surgery was low to compared with grafted with bone cells. 3. In the case of porous hydroxyapatite inoculated with bone cell, less inflammatory cell infiltration and rapid new bone formation activity was revealed than hydroxyapatite only group. Active new bone formation were observed in the early stage of control group. 4. The origin of new bone forming was revealed not from the center of, defected area but from the surface of preexisting bony wall on every specimen. 5. In this experiment, osteoclastic cell was not found around grafted materials, and fibrovascular invasion into regions with no noticeable foreign body reaction. Conclusively, the cultured bone cell inoculated onto the porous hydroxyapatite may have an important role of regeneration of artificial bone defects of alveolar bone.

      • SCIESCOPUSKCI등재

        치근이개부 수평결손시 조직재생에 관여하는 전구세포의 면역세포화학적 연구

        허익,권영혁,Herr, Yeek,Kwon, Young-Hyuk 대한치주과학회 1995 Journal of Periodontal & Implant Science Vol.25 No.2

        The origin of fibroblasts, their proliferative activity and roles in the early stages of periodontal regeneration were investigated in order to better understand the periodontal healing process in furcation defects of the beagle dog after guided tissue regeneration. Newly divided cells were identified and quantitated by immunolocalization of bromodeoxyuridine (BrdU) injected 1 hour prior to sacrificing the animals. The results were as follows :1. During periodontal healing in horizontal furcation defect, three different stages, namely the granulation tissue, connective tissue, and bone formation stages, were identified on the basis of major types of cells and tissue. 2. In the early stages of periodontal regeneration, both the remaining periodontal ligament and alveolar bone compartment were the major sources. 3. The majority of BrdU-labeled fibroblasts were located at the following areas ; 1) the coronal zone of the defect in case of the connective tissue fanned on the root surface. 2) the area within an 400 ${\mu}m$ distance from the remaining bone level in case of the periodontal ligament. 3) the area within an 100 ${\mu}m$ distance from the bone surface in case of areas of active bone formation.4. The highly proliferative fibroblasts adjacent to bone surface played a major role in the formation of osteoblast precursor cells, whereas both paravascular and endosteal cells played a minor role in new bone formation, In conclusion, it was suggested that the fibroblasts in the remaining periodontal ligament and bone will play a major role in periodontal regeneration, whereas both paravascular and endosteal cells will play a minor role in new bone formation.

      • 백서 치아 발거후 잔존 치주인대가 발치와의 치조골 재건에 미치는 영향

        조성훈,허익,박준봉,이만섭,권영혁 慶熙大學校 齒科大學 1995 慶熙齒大論文集 Vol.17 No.2

        The purpose of this study was to observe the effects of the periodontal ligament on the healing and the formation of alveolar bone in the extraction socket, when this ligament had artificially remained in the socket during the tooth removal. Twenty rats aged 4 weeks were used and devided into the control groups (10) and the experimental groups (10) in this study. The maxillary right and left first molars were extracted in both groups. In the experimental groups the periodontal ligament was remained in the extraction sockets using 0.4% fl-aminopropionitrile, and in the control the periodontal ligament was completely removed by curettage. At 1, 3, 5, 7 and 14 days after the tooth extraction, rats in both groups were serially sacrificed. And the specimens were prepared with HematoxyIin-Eosin stain for the light microscopic evaluation. The results ofthis study were as follows ; 1. On 1 day, the periodontal Iigament was only found in the extraction socket walls of the experimental groups, and there was not the distinguishable difference between the control and the experimental groups. 2. On 3 days, there were more collagen fibers and the appearance of higher cellular density in the experimental groups than in the control. And the cells and collagen of the periodontal ligament were so actively proliferated and synthesized that invaded into the connective tissue of the extraction sockets in the experimental groups. 3. In the experimental groups, the trabecular bone was formed on the basal and lateral bone surface on 5 days. However, there was not the new bone forming appearance in the control groups at this time. 4. On 7 days, the trabecular bone was formed in the control groups. 5. On 14 days, the extraction sockets were almost entirely filled with the bony trabeculae in both groups. But, compared to the control group, the experimental groups showed the prominent differences in the amount & the density of the new bone formed. In conclusion, it was suggested that the residual periodontal ligament tissue in the extraction socket will play a major role as the important cell source in the healing and the new bone formation of the extraction socket.

      • SCIESCOPUSKCI등재

        The effect of erbium-doped: yttrium, aluminium and garnet laser irradiation on the surface microstructure and roughness of double acid-etched implants

        Kim, Ji-Hyun,Herr, Yeek,Chung, Jong-Hyuk,Shin, Seung-Il,Kwon, Young-Hyuk Korean Academy of Periodontology 2011 Journal of Periodontal & Implant Science Vol.41 No.5

        Purpose: One of the most frequent complications related to dental implants is peri-implantitis, and the characteristics of implant surfaces are closely related to the progression and resolution of inflammation. Therefore, a technical modality that can effectively detoxify the implant surface without modification to the surface is needed. The purpose of this study was to evaluate the effect of erbium-doped: yttrium, aluminium and garnet (Er:YAG) laser irradiation on the microstructural changes in double acid-etched implant surfaces according to the laser energy and the application duration. Methods: The implant surface was irradiated using an Er:YAG laser with different application energy levels (100 mJ/pulse, 140 mJ/pulse, and 180 mJ/pulse) and time periods (1 minute, 1.5 minutes, and 2 minutes). We then examined the change in surface roughness value and microstructure. Results: In a scanning electron microscopy evaluation, the double acid-etched implant surface was not altered by Er:YAG laser irradiation under the condition of 100 mJ/pulse at 10 Hz for any of the irradiation times. However, we investigated the reduced sharpness of the specific ridge microstructure that resulted under the 140 mJ/pulse and 180 mJ/pulse conditions. The reduction in sharpness became more severe as laser energy and application duration increased. In the roughness measurement, the double acid-etched implants showed a low roughness value on the valley area before the laser irradiation. Under all experimental conditions, Er:YAG laser irradiation led to a minor decrease in surface roughness, which was not statistically significant. Conclusions: The recommended application settings for Er:YAG laser irradiation on double acid-etched implant surface is less than a 100 mJ/pulse at 10 Hz, and for less than two minutes in order to detoxify the implant surface without causing surface modification.

      • SCIESCOPUSKCI등재

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