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Basic Techniques of Intraoperative Neurophysiological Monitoring
( Sang-ku Park ),( Soon-chul Hyun ),( Sung-hyuk Lim ),( Chan-woo Park ),( Jin-woo Park ),( Dong-jun Kim ),( Wan-soo Choi ),( Gi-bong Kim ) 대한임상검사과학회 2013 대한임상검사과학회지(KJCLS) Vol.45 No.2
Intraoperative Neurophysiological Monitoring (INM) is very useful in monitoring the motorsensory pathway and vascular circulation system during intraspinal, or intracranial neurosurgery. Brainstem Auditory Evoked Potentials (BAEPs) are for detecting the problems along the auditory pathways including, the eighth cranial nerve and brainstem. Motor Evoked Potentials (MEPs) is a useful adjunct to conventional monitoring of Somato-sensory Evoked Potentials (SEPs) during surgery. Visual Evoked Potentials (VEPs) has been regarded as having limited significance for the preservation of visual function during neurosurgical procedures. In this paper, we propose that the most appropriate averaging of the number of inspections in the inspection of each used in the operative field, is good and efficient, functionally.
Analysis of Tropospheric Carbon Monoxide in the Northeast Asia from MOPITT
Sang Hee Lee,GI Hyuk CHoi,Hyo Suk Lim,Joo Hee Lee 大韓遠隔探査學會 2003 大韓遠隔探査學會誌 Vol.19 No.3
The Measurement of Pollution in the Troposphere (MOPITT) instrument is an eight-channel gas correlation radiometer that launched on the Earth Observing System (EOS) Terra spacecraft in 1999. Its main objectives are to measure carbon monoxide (CO) and methane (CH4) concentrations in the troposphere. This study analyzes tropospheric carbon monoxide distributions using MOPITT data and compare with ozone distributions in Northeast Asia. In general, seasonal CO variations are characterized by a peak in spring and decrease in summer. Also, this study revealed that the seasonal cycles of CO are maximum in spring and minimum in summer with average concentrations ranging from 118ppbv to 170ppbv. The monthly average of CO shows a similar profile to those of O3. This fact clearly indicates that the high concentration of CO in spring is caused by two possible causes: the photochemical CO production in the troposphere, or the transport of the CO in the northeast Asia. The CO and O3 seasonal cycles in the Northeast Asia are influenced extensively by the seasonal exchange of the different types of air mass due to the Asian monsoon. The continental air masses contain high concentrations of O3 and CO due to higher continental background concentrations and sometimes due to the contribution of regional pollution. In summer the transport pattern is reversed. The Pacific marine air masses prevail over Korea, so that the marine air masses bring low concentrations of CO and O3, which tend to give the apparent minimum in summer.
A Digital Readout IC with Digital Offset Canceller for Capacitive Sensors
Lim, Dong-Hyuk,Lee, Sang-Yoon,Choi, Woo-Seok,Park, Jun-Eun,Jeong, Deog-Kyoon The Institute of Electronics and Information Engin 2012 Journal of semiconductor technology and science Vol.12 No.3
A digital readout IC for capacitive sensors is presented. Digital capacitance readout circuits suffer from static capacitance of sensors, especially single-ended sensors, and require large passive elements to cancel such DC offset signal. For this reason, to maximize a dynamic range with a small die area, the proposed circuit features digital filters having a coarse and fine compensation steps. Moreover, by employing switched-capacitor circuit for the front-end, correlated double sampling (CDS) technique can be adopted to minimize low-frequency device noise. The proposed circuit targeted 8-kHz signal bandwidth and oversampling ratio (OSR) of 64, thus a $3^{rd}$-order ${\Delta}{\Sigma}$ modulator operating at 1 MH was used for pulse-density-modulated (PDM) output. The proposed IC was designed in a 0.18-${\mu}m$ CMOS mixed-mode process, and occupied $0.86{\times}1.33mm^2$. The measurement results shows suppressed DC power under about -30 dBFS with minimized device flicker noise.
Cytotoxic Constituents form the Roots of Anthriscus sylvestris
Lim, Young-Hee,Leem, Moon-Jeong,Shin, Dong-Hyuk,Chang, Hwan-Bong,Hong, Seung-Woo,Moon, Eun-Yi,Lee, Dug-Keun,Yoon, Sung-June,Woo, Won-Sick The Pharmaceutical Society of Korea 1999 Archives of Pharmacal Research Vol.22 No.2
Activity-guided fractionation of the roots of Anthriscus sylvestris resulted in the isolated and characterization of five cytotoxic compounds, deoxypodophyllotoxin (1), falcarindiol (2), and angeloyl podophyllotoxin (5) from the hexane soluble fraction and morelensin (3), bursehernin (4) from the choloroform soluble fraction. It is the first report of the occurrence of compound 5 in nature.
Electrochemical Study on Localized Corrosion of Laser Surface Melted Alloy 600
Lim, Yun Soo,Hur, Do Haeng,Kim, Hong Pyo,Kim, Joung Soo,Kwon, Hyuk Sang 한국부식방식학회 2002 Corrosion Science and Technology Vol.31 No.6
The effects of laser surface melting (LSM) on the resistance to localized corrosion such as intergranular stress corrosion cracking (IGSCC) and pitting of Ni-base Alloy 600 were investigated by electrochemical methods. The degree of sensitization ofthe laser heated Alloy 600 measured using the double loop electrochemical potentiokinetic reactivation method in a 0.1 M Na₂S₄O_6 + 20 ppm KSCN solution was considerably low, which demonstrates that the resistance to IGSCC of Alloy 600 in sulfur bearing environments was improved by LSM. The pitting potentials of Alloy 600 in 1 M NaCl at pH 4 and 9 were also markedly increased by the LSM process, compared with that of the non-laser treated Alloy 600. From the microscopic examination, it was found that pitting was initiated around sulfides associated TiN in the matrix of Alloy 600. Homogeneous microstructure associated with the reduction of inclusion size during LSM could be attributed to the increase of resistance to pitting corrosion in the LSM Alloy 600. On the other hand, complete dissolution of pre-existing intergranular Cr-rich carbides and the resultant Cr healing around grain boundaries was responsible for the improvement of IGSCC properties. The resistance to localized corrosion of the laser treated Alloy 600 was discussed from the results of the electrochemical test and microscopic examination.
A study of Wireless Communication Technology in Unmanned Parking System
Sang-Wook Choi,Young-Hyuk Kim,Il-Kwon Lim,Jae-Kwang Lee 한국콘텐츠학회 2009 ICCC International Digital Design Invitation Exhib Vol.2009 No.12
The present, most of unmanned vehicle sector is using method that attach sensor inside vehicle. But because this method must attach all expensive equipment inside vehicle, many problems can happen. On the other hand, all the world is progressing a research about V2I and V2V. Also, the South Korea is trying to develop service using V2I and V2V by governmental support. In this paper, look into the applicable communication for unmanned vehicle system development, and make an alternative idea to IEEE 802.11 a.
Count-based quantitation of trace level macro-DNA molecules
Lim, Hyuk-Min,Yoo, Hee-Bong,Hong, Nan-Sook,Yang, Inchul,Han, Myung-Sub,Park, Sang-Ryoul Springer-Verlag 2009 Metrologia Vol.46 No.3
<P>Quantitation of the trace amount of DNA by counting individual DNA molecules using a high-sensitivity flow cytometric setup has been developed and evaluated for the purpose of establishing a reference analytical procedure. Model DNA molecules, represented by lambda (λ) viral DNA (48 502 bp, double-stranded), were electro-focused to form a tightly bound flow stream on a detection point situated on the centre axis of fused silica tubing measuring 50 µm × 50 µm. The individual DNA particles that were stained with a fluorescent dye were detected individually with a high-sensitivity laser-induced fluorescence (LIF) detection system. Assuming all DNA particles in a given sample volume were detected and counted (‘exhaustive counting’), its molar concentration can be calculated without the need for calibration materials. The validity of the proposed measurement method was thoroughly examined and discussed.</P>
( Sung Ha Lim ),( Eun Jung Kim ),( Chung Hyuk Lee ),( Gi Hyun Park ),( Kang Min Yoo ),( Sung Ju Nam ),( Kyong-oh Shin ),( Kyungho Park ),( Eung Ho Choi ) 대한피부과학회 2020 대한피부과학회 학술발표대회집 Vol.72 No.1
Background: The stratum corneum (SC) consists of corneocytes, intercellular lipids, and corneodesmosomes. Most of the previous studies have focused on a ceramide with a single chain fatty acid, not with diverse chain lengths. Objective: We evaluated whether a lipid mixture enriched by ceramide NP with fatty acids of diverse chain lengths can restore the skin barrier impaired by topical corticosteroid. Methods: 27 healthy adult males were recruited. Topical corticosteroid was applied on both the forearms and, either the test cream that contains a lipid mixture or a vehicle cream was applied on the left or right forearm, respectively. The functional parameters of the skin barrier, epidermal differentiation markers, hyaluronic acid synthase 3 (HAS3), cytokines, and the lipid profiles in the SC were analyzed. Results: The barrier recovery rate, SC integrity, and SC hydration were significantly improved in the test cream-applied site. Filaggrin and HAS3 levels were significantly higher, Interleukin-1α (IL-1α) levels were increased, and IL-2, IL-6, IL-10, and IL-13 levels decreased in the test cream-applied site. Lipid analysis showed that C18, C20, and total ceramide NP levels increased in the test cream-applied site. C16, C18, C20, C24, and total ceramide NP levels were elevated in the test cream-applied site after acute barrier disruption. Conclusion: A lipid mixture enriched by ceramide NP with fatty acids of diverse chain lengths could recover the barrier impaired by topical corticosteroid.