가스상 대기오염물질에 의한 종이 기록물의 가속열화 특성 연구

정소윤(So-Yoon Jeong),전수연(Soo-Yeon Jeon),백소라(So-Ra Baek),정현석(Hyun-Seok Jeong),이진희(Jin-Hee Lee),김형진(Hyoung-Jin Kim) 한국펄프·종이공학회 2015 펄프.종이기술 Vol.47 No.4

Paper records were generally degraded by some factors from atmospheric environments, like temperature, relative humidity or air pollutants. In this study, the degradation behavior of paper records by single or mixed gases of NO₂, SO₂, HCHO and TVOC was evaluated. The mechanical, optical and chemical properties of 4 kinds of paper (acid and neutral-based printing paper, traditional Hanji, and filter paper) were directly and indirectly affected by gaseous harmful materials. The brightness and L<SUP>*</SUP> value in all papers were slightly increased by accelerated aging under gaseous HCHO and TVOCs, but highly decreased by conditions under gases NO₂ and SO₂. The optical properties of paper records were most vulnerable in acid-based paper and high stable in filter paper and traditional Hanji by air pollutant degradation. The aging treatments under mixed gas pollutants including NO₂ resulted in decrease of physical, mechanical and optical properties of paper, so it was supposed that the concentration of NO₂ gas would be strictly controlled for optimum indoor air quality management in domestic storage centers for paper records.

대기 중 유해성분(NO₂, SO₂, HCHO)에 의해 열화된 종이의 물리적 특성

백소라(So Ra Beck),정소윤(So Yoon Jeong),정현석(Hyun Suk Jung),이진희(Jin Hee Lee),김형진(Hyoung Jin Kim),김신도(Shin Do Kim) 한국펄프·종이공학회 2014 한국펄프·종이공학회 학술발표논문집 Vol.2014 No.10

Complete genome sequence of Sphingobium sp. strain PAMC 28499 reveals a potential for degrading pectin with comparative genomics approach

So‑Ra Han,Sung‑Min Jang,Young Min Chi,Byeollee Kim,정상희,Yung Mi Lee,Jun Uetake,Jun Hyuck Lee,Hyun Park,오태진 한국유전학회 2020 Genes & Genomics Vol.42 No.9

Background Spingobium sp. PAMC 28499 is isolated from the glaciers of Uganda. Uganda is a unique region where hot areas and glaciers coexist, with a variety of living creatures surviving, but the survey on them is very poor. The genetic character and complete genome information of Sphingobium strains help with environmental studies and the development of better to enzyme industry. Objective In this study, complete genome sequence of Spingobium sp. PAMC 28499 and comparative analysis of Spingobium species strains isolated from variety of the region. Methods Genome sequencingwas performed using PacBio sequel single-molecule real-time (SMRT) sequencing technology. The predicted gene sequences were functionally annotated and gene prediction was carried out using the program NCBI nonredundant database. And using dbCAN2 and KEGG data base were degradation pathway predicted and protein prediction about carbohydrate active enzymes (CAZymes). Results The genome sequence has 64.5% GC content, 4432 coding protein coding genes, 61 tRNAs, and 12 rRNA operons. Its genome encodes a simple set of metabolic pathways relevant to pectin and its predicted degradation protein an unusual distribution of CAZymes with extracellular esterases and pectate lyases. CAZyme annotation analyses revealed 165 genes related to carbohydrate active, and especially we have found GH1, GH2, GH3, GH38, GH35, GH51, GH51, GH53, GH106, GH146, CE12, PL1 and PL11 such as known pectin degradation genes from Sphingobium yanoikuiae. These results confrmed that this Sphingobium sp. strain PAMC 28499 have similar patterns to RG I pectin-degrading pathway. Conclusion In this study, isolated and sequenced the complete genome of Spingobium sp. PAMC 28499. Also, this strain has comparative genome analysis. Through the complete genome we can predict how this strain can store and produce energy in extreme environment. It can also provide bioengineered data by fnding new genes that degradation the pectin

A phase III, multicentre, randomised, double-blind, active-controlled, parallel-group trial comparing safety and efficacy of HD203, with innovator etanercept, in combination with methotrexate, in patients with rheumatoid arthritis: the HERA study

Bae, Sang-Cheol,Kim, Jinseok,Choe, Jung-Yoon,Park, Won,Lee, Sang-Heon,Park, Yong-Beom,Shim, Seung-Cheol,Lee, Shin-Seok,Sung, Yoon-Kyoung,Choi, Chan-Bum,Lee, So-Ra,Park, HanYu,Ahn, Yongho H. K. Lewis 2017 Annals of the rheumatic diseases Vol.76 No.1

<P>Conclusion The study met the primary objective of demonstrating equivalent efficacy of HD203 and ETN. HD203 was well tolerated, with safety comparable with ETN in this population of patients with RA.</P>

Poster Session : PS 0691 ; Rheumatology ; A Randomized, Double-Blind, Phase 3 Equivalence Trial Comparing the Etanercept Biosimilar, Hd203, to Reference Etanercept, in Combination with Methotrexate (MTX) in Korean Patients with Rheumatoid Arthritis (RA)

( Sang Cheol Bae ),( Jinseok Kim ),( Jung Yoon Choe ),( Won Park ),( So Ra Lee ),( Yong Ho Ahn ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

Background: Etanercept is a recombinant fusion protein that blocks TNF. HD203 is a biosimilar of etanercept with demonstrated comparability across pharmacokinetics, safety and tolerability. The objectives of this study were to evaluate equivalence in effi cacy and compare safety of HD203 with reference etanercept, in combination with MTX in patients with RA. (ClinicalTrials. gov NCT01270997). Methods: Korean patients (male or female aged =20 years) with active RA were randomized (1:1) to 25 mg HD203 or reference etanercept, administered subcutaneously twice weekly with MTX for 48 weeks. The primary endpoint was the proportion of patients achieving ACR20 at week 24. Secondary endpoints included ACRn, DAS28, andEULAR response at week 24 and 48, safety and immunogenicity. Results: In total, 294 patients were randomized: HD203, n=147; reference etanercept, n=147. The proportion of patients achieving ACR20 at week 24 was not signifi cantly different between HD203 and reference etanercept. Equivalent effi cacy was demonstrated within predefined margins. There were no significant differences between proportions achieving ACR20 at week 12 and 48. ACR50 and ACR70 displayed similar trends. There were no signifi cant differences between groups for ACRn, DAS28, and EULAR response. Safety set analysis (HD203, n=147; reference etanercept, n=146) revealed no signifi cant difference for treatment-emergent (all-causality) adverse events (AEs): HD203 76. 87% vs. reference etanercept 78. 08% (p=0. 8040). No significant differences between HD203 and reference etanercept were observed for adverse drug reactions, serious AEs, or discontinuations due to AEs. Few patients tested positive for anti-drug antibodies. Conclusions: The study met the primary endpoint of demonstrating equivalent effi cacy of HD203 compared to reference etanercept. HD203 was well tolerated, with a safety profi le comparable to reference etanercept in this population of patients with RA.

소멸문화유적의 인식제고 방안 연구 : 서울시 중구·서대문구 문화유적지도 작성을 중심으로 Focused on Creating a Cultural Relic Map of Jung-gu and Seodaemun-gu, Seoul

이재근,백난영,김소라 한국전통조경학회 2003 한국전통조경학회지 Vol.21 No.2

The purpose of preserving our cultural relics is to provide people with a sense of history and belongings. This research is to create a new value for a cultural asset site and its neighborhood places that are valuable and historically significant as well. We have focused on the cultural relics that have been rooted out in the historic and social background. And we have found only small number of milestones remain in Jung-gu and Seodaemun-gu, Seoul. We identified precise locations of the missing cultural relics and analyzed the surrounding environment as of 2002. Based on the findings, we created a cultural relic map of Jung-gu and Seodaemun-gu. The significance of this research was the preparation of a foundation in order to promote and educate citizens by making a cultural relic map of Jung-gu and Seodaemun-gu, Seoul. Existing cultural relics were included as a means to enhance the recongnition of the missing cultural relics of Jung-gu and Seodaemun-gu, Seoul. However, precise methodologocal follow-up researches should be conducted to promote tour services, and to enhance the recongnition of the existing and the missing cultural relics.

상아질 삭제기구가 자가부식 접착제의 결합강도에 미치는 효과

이영곤,문소라,조영곤 大韓齒科保存學會 2010 Restorative Dentistry & Endodontics Vol.35 No.1

이 연구는 다이몬드 포인트와 카바이드 버 및 SiC paper로 삭제한 상아질에 대한 자가부식 프라이머 접착제의 결합강도를 비교하고, 실험실에서 사용하는 SiC paper와 유사한 결합강도를 나타내는 회전용 삭제기구를 알아보기 위하여 시행하였다. 56개의 발거된 대구치 치관의 교합면 상아질을 노출시켜 1.2 mm의 두께의 시편을 제작한 후 8개의 군으로 분류하였다. 1군은 standard diamond point (TF-12), 2군은 fine diamond point (TF-12F). 3군은 extrafine diamond point (TF-12EF), 4군은 cross-cut carbide bur (no. 557), 5군은 plain-cut carbide bur (no. 245), 6군은 P 120-grade SiC paper, 7군은 P 220-grade SiC paper, 8군은 P 800-grade SiC paper를 사용하여 각 시편의 상아질 표면을 약 0.2 mm정도 삭제하였다. 상아질 표면에 Clearfil SE Primer와 Bond를 적용하고 Tygon tube를 이용하여 Clearfil AP-X를 충전하고 40초간 광조사 하였다. 제작된 시편은 만능시험기를 이용하여 를 미세전단 결합강도는 측정한 후, 각 군의 결합강도를 one-way ANOVA와 Tukey검정을 이용하여 분석하여 다음과 같은 결과를 얻었다. 자가부식 프라이머 접착제 사용 시 상아질에 대한 개선된 접착을 위해서는 초미세입자 다이아몬드 포인트의 사용이 추천되며, 실험실적인 연구에서 P 220-grade SiC paper의 사용은 미세입자 다이아몬드 포인트나 카바이드 버로 삭제한 상아질 면과 유사한 결합강도를 나타내었다. The purpose of this study was to compare the microshear bond strength of a self-etching primer adhesive to dentin prepared with different diamond points, carbide burs and SiC papers, and also to determine which SiC paper yield similar strength to that of dentinal surface prepared with points or burs. Fifty-six human molar were sectioned to expose the occlusal dentinal surfaces of crowns and slabs of 1.2 mm thick were made. Dentinal surfaces were removed with three diamond points, two carbide burs, and three SiC papers. They were divided into one of eight equal groups (n = 7); Group 1: standard diamond point(TF-12), Group 2: fine diamond point (TF-12F), Group 3: extrafine diamond point (TF-12EF), Group 4: plain-cut carbide bur (no. 245), Group 5: cross-cut carbide bur (no. 557), Group 6 : P 120-grade SiC paper, Group 7: P 220-grade SiC paper, Group 8: P 800-grade SiC paper. Clearfil SE Bond was applied on dentinal surface and Clearfil AP-X was placed on dentinal surface using Tygon tubes. After the bonded specimens were subjected to uSBS testing, the mean uSBS (n = 20 for each group) was statistically compared using one-way ANOV A and Tukey HSD test. In conclusion, the use of extrafine diamond point is recommended for improved bonding of Clearfil SE Bond to dentin. Also the use of P 220-grade SiC paper in vitro will be yield the results closer to dentinal surface prepared with fine diamond point or carbide burs in vivo.

Weissenberg 寫眞 技法에 의한 酸化마그네슘(MgO)의 結晶構造

이진호,류보영,조소라,김문집,추금홍,서일환,임성수 순천향대학교 1993 논문집 Vol.16 No.3

The structure of MgO crystal is faced centered cubic(FCC) with cell parameters of a=b=c=4.21Å, α=β=γ=90。. The ionic bond length between Mg and O atoms is 2.1Å. This crystal belongs to m3m point group and to Fm3m space group.

신선초의 생장에 대한 이온교환수지의 재배 효과

이소라, 오영제, 김은주, 오영민 忠北大學校 農業科學硏究所 2014 農業科學硏究 Vol.30 No.2

This study was conducted to evaluate effect of ion exchange resins on growth of angelica (Angelica keiskei), and additionally investigated growth response of angelica according to germanium concentration in rhizosphere using the ion exchange resins containing germanium. As a result, the addition of the ion exchange resins induced significant increase of fresh weight and dry weight at 55 days of transplanting, and plant height and leaf area were also showed the similar pattern. Stem diameter and number of petioles were significantly higher in AS-62 and AS-64 treatment than in control. Inorganic elements concentration of angelica plants substantially didn’t show significant differences between control and treatments, but nitrogen, phosphorus, and potassium concentration were higher in treatments than in control. These results showed that the growth of angelica appeared to be promoted due to increased absorption rate of these elements caused by treatment of the ion exchange resins. There were no significant differences between control and treatments in the concentration of calcium, iron and boron, except for magnesium concentration of shoots. Germanium was not detected in the plants. In conclusion, the addition of ion exchange resin containing essential elements to soil showed positive effect on angelica growth.

모시대의 식품이용화 가치 증진을 위한 품질특성

이소라,김수정,김건희 덕성여자대학교 자연과학연구소 2001 자연과학 논문집 Vol.7 No.-

This study was conducted to increase the value as an useful food resources of Adenophora remotiflora. The contents of dietary fiber was 0.25 g/100 g(dry basis) and tannin was 155.2 ppm. The minerals in Adenophora remotiflora identified calcium(31.63 ㎎/㎏), potassium(149.51 ㎎/㎏), magnessium(14.15 ㎎/㎏), iron(1.40 ㎎/㎏), and sodium(1.46 ㎎/㎏). We examined the quality characteristics of Adenophora remotiflora kimchi during fermentation at 20℃ and 4℃. In color, L and a values gradually increassed at both storage temperature, the b values were decreased slightly at both 4℃ and 20℃. The results of pH decreased from 5.43 to 3.60∼4.60 at 20℃ and 4℃. However, tirtaratable acidity increased from 0.96% to 2.29∼3.98%. Also vitamin C and reducing sugar contents decreased during storage at both temperatures. In sensory evaluation, overall acceptability of Adenophora remotiflora kimchi showed lower scores as storage times increased.