The Media Literacy of Residents in Southwestern China During the COVID-19 Epidemic

Shan He(Shan He),Lili Yao(Lili Yao),Xingyu Zhao(Xingyu Zhao),Weiwei Liu(Weiwei Liu) 아시아사회과학학회 2023 International Science Research Vol.3 No.2

Objective To measure residents’ abilities to acquire, analyze and evaluate information on media in southwestern China and to explore its predictive factors. Methods The convenience sampling method was used. A web-based questionnaire survey was conducted among 774 residents during the Spring Festival in 2020. Results Young, highly educated, unmarried, high-income, and urban residents preferred to seek and acquire information about COVID-19 epidemic through new media channels. Elderly residents tended to obtain information through television. Residents with low educational background and rural residents were more dependent on community information media. To analyze residents’ abilities in the judgement of 15 statements about COVID-19, residents with a master’s degree or above (OR = 2.755, [95% CI 1.160-6.542]) had better media literacy in identifying false health information released on social networking. Rural residents (OR = 0.609, [95% CI 0.433-0.855]) had lower media literacy. The total score decreased by 2.6% for every one-year increase of age. Conclusion Residents’ abilities to acquire, analyze and evaluate information were affected by their demographic characteristics in southwestern China. The authorities and local communities should develop different approaches of information dissemination, with the help of traditional and new media. It is important to improve the level of residents' media literacy, in order to achieve better effect in information dissemination and reception.

IL-23 Inhibits Trophoblast Proliferation, Migration, and EMT via Activating p38 MAPK Signaling Pathway to Promote Recurrent Spontaneous Abortion

He, Shan,Ning, Yan,Ma, Fei,Liu, Dayan,Jiang, Shaoyan,Deng, Shaojie The Korean Society for Microbiology and Biotechnol 2022 Journal of microbiology and biotechnology Vol.32 No.6

As a vital problem in reproductive health, recurrent spontaneous abortion (RSA) affects about 1% of women. We performed this study with an aim to explore the molecular mechanism of interleukin-23 (IL-23) and find optimal or effective methods to improve RSA. First, ELISA was applied to evaluate the expressions of IL-23 and its receptor in HTR-8/SVneo cells after IL-23 treatment. CCK-8, TUNEL, wound healing and transwell assays were employed to assess the proliferation, apoptosis, migration and invasion of HTR-8/SVneo cells, respectively. Additionally, the expressions of apoptosis-, migration-, epithelial-mesenchymal transition- (EMT-) and p38 MAPK signaling pathway-related proteins were measured by western blotting. To further investigate the relationship between IL-23 and p38 MAPK signaling pathway, HTR-8/SVneo cells were treated for 1 h with p38 MAPK inhibitor SB239063, followed by a series of cellular experiments on proliferation, apoptosis, migration and invasion, as aforementioned. The results showed that IL-23 and its receptors were greatly elevated in IL-23-treated HTR-8/SVneo cells. Additionally, IL-23 demonstrated suppressive effects on the proliferation, apoptosis, migration, invasion and EMT of IL-23-treated HTR-8/SVneo cells. More importantly, the molecular mechanism of IL-23 was revealed in this study; that is to say, IL-23 inhibited the proliferation, apoptosis, migration, invasion and EMT of IL-23-treated HTR-8/SVneo cells via activating p38 MAPK signaling pathway. In conclusion, IL-23 inhibits trophoblast proliferation, migration, and EMT via activating p38 MAPK signaling pathway, suggesting that IL-23 might be a novel target for the improvement of RSA.

Predictive Value of Excision Repair Cross-complementing Rodent Repair Deficiency Complementation Group 1 and Ovarian Cancer Risk

He, Shan-Yang,Xu, Lin,Niu, Gang,Ke, Pei-Qi,Feng, Miao-Miao,Shen, Hong-Wei Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.5

Objective: We aimed to analyze the association between excision repair cross-complementing rodent repair deficiency complementation group 1 (XRCC1) and ovarian cancer risk. Methods: We performed a hospital-based case-control study with 155 cases and 313 controls in China. All Chinese cases with newly diagnosed primary ovarian cancer between May 2005 to May 2010 in our hospital were invited to participate within 2 months of diagnosis. Controls were randomly selected from people who requested general health examinations in the same hospital during the same period. SNPs in EXCC1, ERCC1 C8092A and ERCC1 T19007C, were analyzed by PCR-RFLP method. Results: We observed a non-significantly increased risk of ovarian cancer among individuals with ERCC1 8092TT compared with those with the 8092CC genotype (adjusted OR=1.55, 95% CI%=0.74-2.97). Moreover, 19007TT genotype carriers also showed a non-significant increased risk of ovarian cancer over those with the 19007CC genotype (adjusted OR=1.78, 95% CI%=0.91-3.64). Conclusion: Our firstly investigation of links between polymorphisms in the ERCC1 gene and the risk of ovarian cancer in Chinese population demonstrated no significant association. Further large sample studies in Chinese populations are needed.

Research on the Innovation Incentive of Manufacturers based on Price Commitment: Heterogeneous Product Perspective

Shan He,Zeming Chen,Chenxi Wang 보안공학연구지원센터 2016 International Journal of u- and e- Service, Scienc Vol.9 No.10

This paper considers two kinds of heterogeneous products and establishes the supplier’s and the manufacturer's dynamic game models under flexible price strategy and price commitment strategy respectively. The equilibrium solution and the optimal expected profits of supply chain members are obtained by using backward induction. By comparing the equilibrium solution under two different strategies, the impact of price commitment strategy provided by the manufacturer on the innovation, order quantity, and the wholesale price of the supplier is analyzed, and the impact of transmuting degrees of products and efficiency of innovation on price strategy is analyzed. Meanwhile, by comparing the supply chain members’ optimal expected profits under two different strategies, the impact of price commitment strategy provided by the manufacturer on the profits of manufacturer, supplier and the whole supply chain is analyzed. On this basis, a risk compensation strategy is designed, and it is verified that the compensation strategy can guarantee the supply chain members to achieve a win-win situation.

Prevention and control strategies for unintentional injuries of children in kindergartens/schools

He Shan(何姗,),Liu Weiwei(刘,薇薇) 아시아사회과학학회 2022 International Science Research Vol.2 No.1

教师是托幼机构/学校学龄前和学龄儿童生活环境的主要创造者。加强托幼机构/学校内儿童意外伤害的防控,是全社会开展儿童安全防护工作中的重要一环。托幼机构/学校开展儿童意外伤害防控工作的策略包括:加强托幼机构/学校伤害监测数据分析,创新培养方式、开展教师培训,对环境和产品设计进行技术革新,完善政策制度体系,加强校医人才队伍建设等。 Teachers are the main creators of the living environment of preschool and school-age children in kindergartens/schools. Strengthening the prevention and control of children s unintentional injuries in kindergartens/schools is an important part of the whole society s work of child safety protection. The strategies for childcare institutions/schools to carry out child unintentional injury prevention and control include: strengthening the analysis of injury monitoring data of childcare institutions/schools, innovating training methods, carrying out teacher training, carrying out technical innovation in environment and product design, improving policy and system, and strengthening the construction of school medical talents, etc.

Study on Manufacturers’ Innovation Incentive Based on Price Commitment under Products Competition

Shan He,Chenxi Wang 보안공학연구지원센터 2016 International Journal of u- and e- Service, Scienc Vol.9 No.10

Under the situation of highly competition among downstream manufacturers, this research establishes two game models composed of one supplier and two manufacturers under the circumstance of price flexibility strategy and price commitment strategy offered by the supplier separately. The equilibrium and optimal expected profits of all supply chain members are obtained by using backward induction. Meanwhile, this research analyses the impact of price commitment strategy on the creativity of innovative manufacturers, profits of supply chain members and expected profits of whole supply chains by comparing the equilibrium and optimal expected profits under two different strategies. On the basis of preview study, a revenue sharing strategy is designed, and it is verified that the compensation strategy can guarantee the supply chain members to achieve a win-win situation.

Anti-tumor activities of Panax quinquefolius saponins and potential biomarkers in prostate cancer

Shan He,Fangqiao Lyu,Lixia Lou,Lu Liu,Songlin Li,Johannes Jakowitsch,Yan Ma 고려인삼학회 2021 Journal of Ginseng Research Vol.45 No.2

Background: Prostate carcinoma is the second most common cancer among men worldwide. Developing new therapeutic approaches and diagnostic biomarkers for prostate cancer (PC) is a significant need. The Chinese herbal medicine Panax quinquefolius saponins (PQS) have been reported to show anti-tumor effects. We hypothesized that PQS exhibits anti-cancer activity in human PC cells and we aimed to search for novel biomarkers allowing early diagnosis of PC. Methods: We used the human PC cell line DU145 and the prostate epithelial cell line PNT2 to perform cell viability assays, flow cytometric analysis of the cell cycle, and FACS-based apoptosis assays. Microarray-based gene expression analysis was used to display specific gene expression patterns and to search for novel biomarkers. Western blot and quantitative real-time PCR were performed to demonstrate the expression levels of multiple cancer-related genes. Results: Our data showed that PQS inhibited the viability of DU145 cells and induced cell cycle arrest at the G1 phase. A significant decrease in DU145 cell invasion and migration were observed after 24 h treatment by PQS. PQS up-regulated the expression levels of p21, p53, TMEM79, ACOXL, ETV5, and SPINT1 while it down-regulated the expression levels of bcl2, STAT3, FANCD2, DRD2, and TMPRSS2. Conclusion: PQS promoted cells apoptosis and inhibited the proliferation of DU145 cells, which suggests that PQS may be effective for treating PC. TMEM79 and ACOXL were expressed significantly higher in PNT2 than in DU145 cells and could be novel biomarker candidates for PC diagnosis.

구성원들의 조직시민행동을 어떻게 높이는가? : 그릿의 매개효과

하선숙(He, Shan-Shu),전정호(Jeon, Jeong-Ho),이의연(Li, Yi-Ran) 한국산업경제학회 2021 산업경제연구 Vol.34 No.5

본 연구에서는 구성원들의 조직시민행동을 지속적으로 높이기 위하여, 일의 의미, 육성적 피드백, 그릿의 구조적 인과관계를 파악하고 SmartPLS의 구조방정식 모형을 이용하여 검증하였다. 이러한 목적을 달성하기 위해 2021년 7월 15일부터 2021년 7월 20일까지 예비조사를 실시하여, 설문지의 오류와 미흡한 부분을 수정하였다. 설문지의 2차 배포 및 회수는 Amazon Mechanical Turk의 온라인 설문을 사용하여 2021년 7월 23일부터 2021년 7월 26일까지 설문조사를 실시하였고, 309부를 최종분석에 사용되었다. 연구결과, 일의 의미와 육성적 피드백이 그릿을 매개로 조직시민행동에 유의한 영향을 미치는 것으로 나타났다. 이론적 시사점은 본 연구를 통해 선행연구에서 제시된 일의 의미와 육성적 피드백의 효과를 재확인하고, 일의 의미와 육성적 피드백이 사회정체성이론과 사회교환이론을 통해 그릿을 매개로 조직시민행동에 미치는 영향을 실증 · 분석하였다는 데 이론적 함의를 가진다. 실무적 시사점은 본 연구결과를 통해 기업에서 구성원들이 업무를 완수하는 과정에서 조직시민행동이 중요하지만, 일의 의미와 육성적 피드백, 그릿에 의해 지속적 조직시민행동이 가능함을 밝히는 데 의의가 있다. This study assessed and validated the causative structural relationships among the meaning of work, developmental feedback, and grit to influence members’ organizational citizenship behavior, using the structural equation model of SmartPLS. To achieve this purpose, this study corrected errors in questionnaires and inadequate parts by conducting a preliminary survey from July 15 through 20, 2021. For the secondary distribution and collection of questionnaires, a survey was conducted, using an online survey of Amazon Mechanical Turk from July 23 through 26, 2021, and 309 copies were used in the final analysis. The findings of this study demonstrated that the meaning of work and developmental feedback had significant impacts on organizational citizenship behavior using grit as a medium. This study has theoretical implications in that it re-validated the meaning of work and the effect of developmental feedback presented in the preceding studies and that it demonstrated and analyzed the impact on organizational citizenship behavior using grit as a medium through, the meaning of work and developmental feedback. As for a practical implication, the findings of this study demonstrated that organizational citizenship behavior is important in the process in which the members of enterprises complete tasks, but more importantly, this study is significant in that it reveals that continuous organizational citizenship behavior is possible by the meaning of work, developmental feedback, and grit.

상사-부하 교환관계가 조직시민행동에 미치는 영향: 심리적 임파워먼트와 무형식 학습의 이중매개효과

하선숙(He, Shan-Shu),이의연(Li, Yi-Ran),전정호(Jeon, Jeong-Ho) 한국산업경제학회 2020 산업경제연구 Vol.33 No.6

4차 산업혁명이 도래하면서, 기업들도 기존의 획일적 정책 부분에서 탈피하여 지속가능한 경영 및 혁신을 위해 다양한 노력을 기울이고 있다. 따라서 본 연구는 이러한 변화무쌍한 경영환경을 고려하여, LMX가 심리적 임파워먼트, 무형식 학습, 그리고 조직시민행동에 미치는 영향과 심리적 임파워먼트와 무형식 학습의 이중매개효과를 실증·분석하였다. 연구목적을 달성하기 위해 수도권에 소재한 대기업에 재직하고 있는 구성원 325명의 응답을 표본으로 SPSS 27.0, Amos 27.0을 이용하여 분석하였다. 연구결과, 첫째, LMX는 조직시민행동에 정(+)의 영향을 미치는 것으로 나타났다. 둘째, 심리적 임파워먼트와 무형식학습은 LMX와 조직시민행동의 관계에서 매개역할을 하는 것으로 나타났다. 셋째, LMX와 조직시민행동의 관계에서 심리적 임파워먼트와 무형식 학습은 이중 매개역할을 하는 것으로 나타났다. 시사점은 다음과 같다. 이론적 시사점은 본 연구를 통해 선행연구에서 제시된 LMX의 효과를 재확인하고, LMX가 사회교환관계를 통해 이론적 확장에 기여하였다. 실무적 시사점은 본 연구결과를 통해 실제 기업에서 조직의 목표를 효율적이고 효과적으로 달성하는 데 구성원들의 조직시민행동이 필요하고, 이를 강화시키는 방안을 시사하였다. The purpose of this study is to examine the impact of leader-member exchange on psychological empowerment, informal learning, and organizational citizenship behavior and to analyze the dual mediation effect of psychological empowerment and informal learning. The authors used 325 questionnaires collected by members in domestic companies. The results showed that leader-member exchange has no positive effect on organizational citizenship behavior. We found also that psychological empowerment and informal learning mediates the effect of leader-member exchange on organizational citizenship behavior, respectively. Furthermore, in the relationship between leader-member exchange and organizational citizenship behavior, psychological empowerment and informal learning play a dual mediating role. Present paper contributes to theoretical expansion by explaining that these behavior patterns are identified by social exchange theory. The practical implication is that this study confirmed that members in the actual management field are willing to perform organizational citizenship behavior in order to achieve the organization’s goal efficiently and effectively.

애니메이션 캐릭터의 귀여움 표현 요소 연구 : 이등신 캐릭터를 중심으로

하산(Shan He),박성원(Sung-Won Park) 한국데이타베이스학회 2020 Journal of information technology applications & m Vol.27 No.4

Animation is a field of popular visual art that is established in human life, and the form of characters appearing is an important factor that is highly anticipated by the public. Designing animation characters according to aesthetic characteristics not only satisfies people’s aesthetic needs but can also increase their artistic immersion in animation works. In addition, animation storytelling is delivered around characters and enhances the value of the work by encouraging more public to focus on it. In this paper, we tried to analyze the design elements of Minions characters to derive the reason why they are loved by the public. Among the morphological characteristics of bicepsin characters, a study was conducted on the fact that bicepsin characters visually express ‘cute’ through the study of infantile eating and color. The visual cuteness elements of a bisung character will soon be linked to the psychological satisfaction of the audience’s work and will be a factor in the appreciation of the value of the work. By studying the elements of expression that represent isosin characters, I would like to discuss the factors that help the audience to immerse and get satisfaction with the characters. This will be used as an important factor for an animation character to have for the audience and will reveal its value. Second-class animation images belong to the art of small pieces, suitable for all the audience to enjoy. The two-size animated image has a strong appeal and entertainment, is a confusing visual attribute, can stimulate the audience’s five senses. Compared with the actors in the movie, the visual form of the animation is more important.