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WDM-PON용 Bi-Di Ferrule 연마기 및 연마기술 개발에 관한 연구
김재열,허상휴,고명석,송경석,유신 한국공작기계학회 2007 한국공작기계학회 추계학술대회논문집 Vol.2007 No.-
WDM-PON(Wavelength Division Multiplexer) was known as solution of ultimate FTTH(Fiber-To-The-Home) in big city and internet network. Optical module part among whole system is the most difficult technologically, it is getting into bottle-neck of development. Quality, all prices are many up to now assignments to be satisfied, it can be said that is early phase. In this treatise I wish to develop WDM-PON Bi-Di Ferrule polishing machine and a polishing technology that use ferule polishing horn in Bi-Di that is an existing technology.
Bacillus lentimorbus WJ5의 감마선유도 돌연변이체들에서 공통으로 발현되는 방사선 관련 유전자의 microarray 분석
이영근,장화형,장유신,허재호,형석원,정혜영 한국환경생물학회 2004 환경생물 : 환경생물학회지 Vol.22 No.3
본 연구에서는 감마선으로 유도된 돌연변이체들에서 공통으로 발현되는 방사선 관련 유전자들의 발현을 연구하기 위하여, B. lentimorbus WJ5의 방사선 유도 돌연변이체에서 발현되는 유전자를 DNA microarray로 동시에 탐색하였다. DNA microarray는 B. lentimorbus WJ5 genome을 무작위로 절단하여 2,000단편으로 구성하였으며, 감마선 (^(60)Co)으로 유도된 7돌연변이체의 발현을 정량적으로 관찰하였다. 클러스터 분석결과 발현된 408 유전자 중 27개가 감마선 유도 돌연변이체 모두에서 유의하게 발현이 증가되었다. 특히, 복구(mutL, mutM)에너지 대사 (acsA, sdhB, p하, yhjB, citB), protease(npr), 산화자극에 대한 환원 (HMM)관련 유전자들이 동시에 증가되었다. 이는 감마선 유도 돌연변이체들에서 자발적인 직/간접 복구 관련 유전자의 발현 증가는 방사선 노출 직후 보이는 stress response와는 다른 현상임을 나타내는 것으로 생각된다. To study the radiation related gene expression in mutants of Bacillus lentimorbus WJ5 induced by gamm radiation, the simultaneous gene expression was analyzed by DNA microarray. We constructed DNA chips including two thousand randomly digested genome spots of B. lentimorbus WJ5 and compared its quantitative aspect with seven mutants induced by gamma radiation (^(60)Co). From the cluster analysis of gene expression pattern, totally 408 genes were expressed and 27 genes were significantly upregulated by the gamma radiation in all mutants. Especially, genes involved in repair (mutL, mutM), energy metabolism (acsA, sdhB, pgk, yhjB, citB), protease (npr), and reduction response to oxidative stress (HMM) were simultaneously upregulated. It seems that the induction of the direct and/or indirect repair related genes in mutants induced by gamma radiation could be remarkably different from the adaptive responses against acute exposure to radiation.
Detection of L-Xylosone and its Physiological Effects in Saccharomyces cerevisiae
Seok, Yeong-Jae,Yang, Kap-Seok,Kang, Ju-Gyeong,Kim, Seong-Tae,Huh, Won-Ki,Kang, Sa-Ouk The Microbiological Society of Korea 1996 The journal of microbiology Vol.34 No.2
L-Xylosone was detected as its quinoxaline derivative in the degradation solution of dehydro-L-ascorbic acid. The production rate of L-xylosone was much faster in aerated phosphate-cirate buffer (pH 5. 6) than in pure water. L-Xylosone and dehydro-L-ascorbic acid were identified in the crude extracts of Saccharomyces cerevisiae. The concentration of L-xylosone in the crude cell extracts was calculated to be about 0.2 nmol $(mg protein)^{-1}$. When L-xylosone was added to asynchronous culture of S. cerevisiae, it inhibited primarily the synthesis of protein and RNA. Examination of the effect of L- xylosone on synchronous culture of the yeast indicated that L-xylosone inhibited the initiation of DNA replication and that the cells were arrested at $G_1$, stage of cell division cycle. These results suggested a possibility that L-xylosone can act as an inhibitor of cell growth.
A Giant Unruptured Right Coronary Sinus of Valsalva Aneurysm
Seok-Jae Huh,박태호,Dong-Yeol Lee,Hyojin Kang,Bo-Sung Kim,Yong-Rack Cho,김무현,김영대,Sun-Mi Lee 한국심초음파학회 2012 Journal of Cardiovascular Imaging (J Cardiovasc Im Vol.20 No.1
There have been few case reports on giant sinus of Valsalva aneurysm (SVA). We report a case of a giant unruptured right coronary SVA that was confused with a pericardial cyst by transthoracic echocardiography.
Jae Myoung Noh(노재명),Won Park(박원),Seung Jae Huh(허승재),Doo Ho Choi(최두호),Jung Hyun Yang(양정현),Seok Jin Nam(남석진),Jeong Han Kim(김정한),Young Hyuck Im(임영혁),Jin Seok Ahn(안진석) 대한방사선종양학회 2008 Radiation Oncology Journal Vol.26 No.1
목 적: 조기 유방암에서 유방보존치료와 유방절제술의 치료 성적을 비교하고, 예후 인자를 알아보고자 하였다. 대상 및 방법: 1994년 9월부터 2002년 12월까지 본원에서 근치적 수술을 받은 병리학적 병기 T1~2N0 유방암 환자 1,200명을 후향적으로 분석하여 유방보존치료와 유방절제술을 사이의 차이를 비교해 보았다. 결 과: 분석에 포함된 1,174명의 환자 중 601명이(51.2%) 유방보존치료를 받았고 573명이(48.8%) 유방절제술을 받았다. 유방절제술을 받은 군에서 유의하게 종양의 크기가 컸고, 다발성(multicentricity), 에스트로겐 및 프로게스테론 수용체 음성 등의 인자가 더 많은 경향을 보였다. 유방보존치료 및 유방절제술을 받은 환자의 10년 생존율은 각각 91.96%와 91.01%였고(p=0.1274), 10년 무병생존율은 각각 80.48%와 84.95% (p=0.8795)로 유의한 차이를 보이지 않았다. 결 론: 조기 유방암에서 유방보존치료 내지는 유방절제술을 받은 군 사이에 환자 특성의 차이는 일부 있었으나 생존율에서 유의한 차이를 보이지 않았다. Purpose: To compare the treatment outcomes and to analyze prognostic factors between the use of a breast-conserving treatment (BCT) and a mastectomy for early stage breast cancer. Materials and Methods: We retrospectively reviewed 1,200 patients with pathological stage T1-2N0 breast cancer who received surgery between September 1994 and December 2002 at Samsung Medical Center. We compared the patient characteristics and treatment outcomes between the two treatment groups. Results: Among the 1,174 eligible patients, 601 (51.2%) patients received a BCT and the remaining 573 (48.8%) patients received a mastectomy. The mastectomy group of patients had significantly more cases with a larger tumor size, multicentricity, extensive intraductal component, and estrogen- and progesterone-receptor negativity. The ten-year overall survival rates (OS) of the BCT and mastectomy groups were 91.96% and 91.01%, respectively (p=0.1274). The ten-year disease-free survival rates (DFS) were 80.48% for the BCT group of patients and 84.95% for the mastectomy group of patients, respectively (p=0.8795). Conclusion: Our study shows some differences in patient characteristics between the two treatment groups. However, these differences did not result in significant survival differences.
Huh, Young Jae,Huh, Kyung-Hoe,Kim, Hong-Kyun,Nam, Shin-Eun,Song, Hye Yoon,Lee, Joo-Hoon,Park, Young-Seok The Angle Orthodontist 2014 The Angle orthodontist Vol.84 No.2
<B>ABSTRACT</B><B>Objective:</B><P>To investigate the constancy of the angle between the Frankfort horizontal plane (FH) and the sella-nasion line (SN) using longitudinal data.</P><B>Materials and Methods:</B><P>Longitudinal lateral cephalometric data of 223 children (116 girls and 107 boys) from 6 to 14 years of age were used. The angle between FH and SN (SNFH), the distance from FH to the nasion (NFH), the distance from FH to the sella (SFH), and the differences between the NFH and SFH (Δ) were also measured. All data were analyzed statistically using independent t-tests and mixed-effect regression model analysis.</P><B>Results:</B><P>The mean SNFH values showed some minor fluctuations, ranging from 9.26° to 9.74° in girls and 8.45° to 8.95° in boys. The mean NFH and SFH values gradually increased according to age irrespective of sex. There were statistically significant differences by sex for all measurements at several ages. The annual change in SFH and Δ showed sexual dimorphism.</P><B>Conclusions:</B><P>There are variations among individuals in the angle between the FH and SN. However, within an individual, the angle does not vary significantly over time during the observation period.</P>
( Seok Jae Huh ),( Su Ee Lee ),( Ji Hyun Lee ),( Hyun Hwa Yoon ),( Sung Yong Oh ),( Sung Hyun Kim ),( Hyuk Chan Kwon ),( Hyo Jin Kim ) 대한내과학회 2011 대한내과학회 추계학술대회 Vol.2011 No.1
Objective: Abnormal hemostasis in cancer patients has previously been studied. The principal objective of this study is to determine whether preoperative coagulation factors are related with the clinicopathologic characteristics and to clarify which coagulation factors have prognostic significance in operable colorectal cancer patients. Patients and Methods: This study evaluated 170 patients who underwent curative surgery for colorectal carcinoma. Preoperative coagulation tests included platelet, prothrombin time (PT), activated partial thromboplastin time (aPTT), fibrinogen, D-dimer, fibrinogen degradation product (FDP). The clinicopathological variables including age, gender, tumor location (rectum/colon), preoperative carcinoembryonic antigen (CEA), tumor size (≥5cm vs. <5cm), depth of tumor invasion, lymph node metastasis, stage, lymphovascular invasion, and histologic differentiation were analyzed. Progression-free survival and overall survival were analyzed by Kaplan-Meier analysis. Results: The median age of analyzed patients was 63 years (range; 28~84). Male to female ratio was 62:38. The median follow-up duration was 21.05 months (range; 0.30-56.30). Higher plasma fibrinogen, PT and PLT levels were associated with larger tumor size (p<0.001, p=0.005, and p=0.004, respectively). Higher plasma fibrinogen level was significantly associated with depth of tumor invasion and stage (p=0.014 and p=0.036, respectively). Median progression-free survival was 10.2 month. Overall survival was not reached on median value. However, serum plasma fibrinogen showed no significant factor in predicting progression-free survival and overall survival. Conclusion: Preoperative plasma fibrinogen level is significantly associated with tumor size and depth of tumor invasion. Thus, plasma fibrinogen level might suggest increased early tumor burden. However, plasma fibrinogen did not show a prognostic value.
신뢰성 향상과 성능개선을 위해 다양한 Erasure 코드를 적용한 SSD 기반 RAID-6 시스템 구조
송재석(Jae-Seok Song),허준무(Joonmoo Huh),양유석(Yu-Seok Yang),김덕환(Deok-Hwan Kim) 大韓電子工學會 2010 電子工學會論文誌-CI (Computer and Information) Vol.47 No.6
전통적인 대용량 스토리지 시스템을 위해 하드디스크 기반의 RAID 시스템이 사용되고 있다. 그러나 하드디스크 기반의 RAID 시스템은 외부의 충격에 약하기 때문에 데이터의 신뢰성이 낮고 스핀들 모터의 빈번한 동작으로 인해 전력소모가 많다. 따라서 본 논문에서는 하드디스크를 대체하여 다양한 Erasure 코드를 적용한 SSD 기반 RAID-6 시스템을 제안한다. 제안된 방법으로 Reed-Solomon, EVENODD, Liberation 코딩 기법을 파일시스템 레벨과 디바이스 드라이버 레벨에 각각 적용하였다. 그리고 SSD의 수명저하에 미치는 영향을 최소화하기 위하여 데이터 할당 기법을 적용하였다. 제안된 Erasure 코드가 적용된 RAID-6 시스템에 HDD 와 SSD 를 사용하여 실험한 결과 Liberation 코드가 다른 코드에 비해 SSD 수명저하에 영향을 적게 끼침을 파악하였으며, Erasure 코드들을 파일시스템 레벨에 적용 하였을 경우보다 디바이스 드라이버 레벨에 적용하였을 때 성능이 더 높았다. 또한 HDD를 기반으로 사용하였을 경우 보다 SSD 를 기반으로 사용하였을 경우에 입출력 성능이 4.5%~8.5% 더 향상 되었고 전력소모는 18%~40% 절감되었다. HDD-based RAIDs have been used in high-capacity storage systems for traditional data server. However, their data reliability are relatively low and they consume lots of power since hard disk drive is weak on shock and its power consumption is high due to frequent spindle motor operation. Therefore, this paper presents new SSD based RAID system architecture using various erasure codes. The proposed methode applys Reed-Solomon, EVENODD, and Liberation coding schemes onto file system level and device driver level, respectively. Besides, it uses data allocation method to minimize the side effect of reducing the lifespan of SSD. Detail experimental results show that Liberation code increase wear-leveling rates of SSD based RAID-6 more than other codes. The SSD based RAID system applying erasure codes at the device driver level shows better performance than that at the file system level. I/O performance of RAID-6 system using SSD is 4.5%~8.5% higher than that of using HDD and the power consumption of the RAID system using SSD is 18%~40% less than that of using HDD.