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      • 1866∼7년 데이 드레스(day dress)의 설계 및 디자인 분석

        김문숙,이서희,오현남,한성지,김현주 서울여자대학교 자연과학연구소 1996 자연과학연구논문집 Vol.7 No.-

        As the current stage of the fashion begins to follow the styles of the past, the study on the past costume is getting more important, and as the methodology of the study accurately approached study through the rehabilitation of the past costume is more needed than the simple rearrangement of the historical documents. By this methodology, this study can be positioned as a recreation activity. The results of the study are as follows. 1) Style : The general silhouetts is the late crinoline style which is the period from 1860s to just before bustle. The dress is one-piece composed of fitted bodice, and skirt which the front is flat, side and back is triangular shape to the skirts. 2) Color and Material : the main color is pale stone and the sub-color is ivory and blue. The dress is made of a silk surface and cotton back and partly satin and velvet. 3) Pattern and sewing : the dress is together sewing comnined with lining and fabric. The skirt is gored skirt, the number of patterns is plenty because of the plenty of width of skirt. The double piping has various effect not only to decorate but also to conceal the seam, support the silhouette. 4) Detail : The general detail is double piping which are repeatedly used to decorate stand collar, bands of sleeve, froint bodice and gored panel seam of skirt. And the fringe and velvet ribbon are used to decorate the dress. 5) Structural characteristics : The double piping, velvet ribbon and twilled cotton are used to emphasize structural characteristics of crinoline style. And the waistband which is backed with a webbing band to reinforce it is also the structural characteristics. Synthetically, the 1886~7 day dress has the characteristics of transitional stage in which the chararcteristics of the costume of 1860s and the remnants of the characteristics of the previous costume style, and shows the characteristics of day dress well in terms of the style, color and fabrics, pattern and sewing, detail, and structural characteristics.

      • 현장관측을 통한 목포항 인근의 조류특성 분석

        강주환,오남선,문승록,박선중 국립7개대학공동논문집간행위원회 2003 공업기술연구 Vol.3 No.-

        Tidal characteristics have changed severely after constructions of seadike/seawalls near Mokpo Harbor. Tidal velocity of three layers, buoy paths and suspended sediment distributions are observed near there. The results can be useful database for calibrations of various numerical simulations for coastal and estuarine studies near Mokpo coastal zone.

      • 간 세포암에서 VEGF, TGF-β1, b-FGF 발현의 의의

        김성용,남충현,주종우,채만규,백무준,이문수,김형철,안현철,김홍수,김창진,김창호 순천향의학연구소 2001 Journal of Soonchunhyang Medical Science Vol.7 No.1

        Purpose: Angiogenesis is important for the proliferation and the metastasis of solid tumors. The growth of a solid tumor is widely recognized to depend on the process of neovascularrozation. Without angiogenesis, tumors cease to grow beyond even a few milimeters in diameter. It has been shown that tumor vascular density is an independent prognostic marker in several types of human tumors and is known to correlate with poor prognosis. To date, many angiogenic factors have been identified, such as transforming growth factor-α(TGF-α), transforming growth factor-β(TGF-β), fibroblast growth factor family(FGF), vascular endothelial growth factor(VEGF), platelet derived endothelial cell growth factor(PD-ECGF), tumor necrosis factor-α(TNF-α), and angiogenin. Hepatocellular carcinoma(HCC) is the second most common tumor in Korean males and is known as a typical hypervascular tumor with frequent portal vein invastion. The authors identified the expreesion of VEGF, TGF-β1, and b-FGF in HCC specimens and evaluated the relationship between these growth factors and the clinicopathologic characteristics of HCC. Method: We reviewed the medical records of 30 patients who were diagnosed as hepatocellular carinoma treated with hepatic resection between January 1994 and December 1998 in Soonchunhyang University Chunan Hospital. The selection of the cases was decided according to the condition of paraffin block fixation. The prognostic factors such as age, sex, tumor size, concentration of serum α-fetoprotein, presence of liver cirrhosis, presence of tumor emboli in portal vein, TMN stage, amount of transfusion during the operation, hepatitis B virus(HBV) infection, and Edmonson-Steiner(E-S) grade were investigated. Relationship between the prognostic factors and the immunopathologic expression of the TGF-β1, b-FGF, and VEGF was examined. Result: Thirty patients (24 males, 6 females) were included in the current study. The patient's mean age was 50.6 years and the age ranged from 36 to 65 years. The mean size of the tumor was found to be 5.2cm. All the patients were follewed up for 7 to 63 months. Child's classification A patients were 23(76.7%)cases, B patients were 7(23.3%)cases, and C was none. Immunohistochemical staining of HCC tumor mass in VEGF expression patients were 17(56.7%), b-FGF expression patients were 10(33.3%), and TGF-β1 expression patients were 10(33.3%). VEGF expression or more than one positive expression among the three factors correlated with tumor size and the stage of HCC but did not correlated with other clinicopathological characteristics. TGF-β1 and b-FGF did not correlate with any clinicopathological characteristics. Conclusion: The results suggest that the expression of VEGF or more than one positive expression among the three factors in HCC cells may be a significant prognostic factor of HCC.

      • KCI등재후보

        병원획득 Klebsiella pneumoniae 균혈증 분석을 통해 본 Ciprofloxacin 내성과 Extended-Spectrum β-Lactamase생성 간의 연관성

        김미영,추은주,곽이경,송문희,나성수,송태준,김성혜,전재범,최상호,정진용,김남중,김양수,우준희,류지소 대한감염학회 2004 감염과 화학요법 Vol.36 No.5

        목적 : K. pneumoniae는 ciprofloxacin내성 증가가 전세계적으로 문제가 되고있는 extended-spectrum beta-lactamase (ESBL)를 생성하는 대표적인 세균으로 최근 외국에서 ciprofloxacin 내성과 ESBL 생성사이에 관련이 있다는 2-3편의 보고들이 있었다. 본 연구에서는 병원획득 K. pneumoniae 패혈증이 있었던 환자들을 대상으로 ciprofloxacin 내성과 관련된 인자를 알아보고자 하였다. 재료 및 방법 : 2001년 1월 부터 2002년 12월 사이에 2200병상의 3차 의료기관인 한 대학병원에서 입원 후 72시간 이후에 나간 혈액배양에서 K. pneumoniae가 배양된 입원환자를 대상으로 의무기록과 전산기록을 분석하여 환자의 성별, 나이, 병동, 기저질환, 이전의 항생제 사용력, 패혈증 발생당시까지의 재원기간, 이전 입원력, 원인균의ESBL 생성유무 등을 파악하였고 이들 변수가 ciprofloxacin 내성과 관련이 있는지를 분석하였다. 재발성 패혈증의 경우는 첫 번째 경우만을 분석에 포함하였다. 결과 : 연구대상 환자는 총154명이었고 K. pneumoniae의 ciprofloxacin에 대한 내성률은 28.6% (44/154)였다. Ciprofloxacin 내성균주 중 ESBL 생성균주의 비율은 95.5% (42/44)였고 ciprofloxacin 감수성균주에서 ESBL 생성균주의 비율은 24.5% (27/110)였다(P<0.001). ESBL생성외에 단변량 분석에서 유의한 관련을 보인 변수로는 남자, 나이가 많은 경우, 패혈증 당시 중환자실 재원, 기저질환이 고형암, 혈액암, 담도계 질환인 경우, 패혈증 발생이전 1달 이내의 항생제 사용력, 3세대 cephalosporin, metronidazole, fluroquinolone, carbapenem 투여력이 있었다. 다변량 로지스틱 분석을 시행 하였을 때는 나이가 많은 경우(Adjusted odds ratio[A0R]; 1.04, 95%confidence interval[CI]; 1.01-1.06)와 ESBL 생성(AOR; 81.35, 95% CI; 17.76-372.53)이 유의하게 ciprofloxacin 내성과 관련이 있었다. 결론 : 패혈증을 일으킨 병원획득 K. pneumonias에서의 ciprofloxacin 내성은 ESBL 생성과 유의한 관련을 보였고 향후 이에 관련된 원인이나 기전을 분석하기위한 분자역학적·분자생물학적 연구가 필요하겠다. Background : Strains of ciprofloxacin-resistant Klebsiella pneumoniae have emerged worldwide. We investigated the epidemiology of ciprofloxacin resistance and its relationship to ESBL production in nosocomial K. pneumoniae bacteremia. Materials and Methods : Using the computerized database of clinical microbiology, we identified all patients whose blood culture had yielded K. pneumoniae between January 2001 and December 2002 at a 2200-bed university-affiliated tertiary-care hospital. During the study period, total of 392 episodes of K. pneumoniae bacteremia were documented of which 163 episodes were acquired nosocomially. 9 cases of recurrent episodes were excluded. Results : The resistance rates to ciprofloxacin was 28.6% (44/154). ESBL-production was significantly more common in ciprofloxacin-resistant isolates than in ciprofloxacin-susceptible isolates (95.9% [42/44] vs. 24.5% [27/110], P<0.001). In univariate analysis, following factors were significantly associated with resistance to ciprofloxacin: older age, male sex, ICU admission at the time of bacteremia, prior use of antibiotics within 1 month before bacteremia, solid tumor, hematological malignancy, or biliary disease as underlying disease, and ESBL-production. The prior use of 3^(rd)-generation cephalosprins, metronidazole, fluroquinolone, or carbapenem were also risk factors. Independent risk factors for ciprofloxacin resistance were older age (adjusted odds ratio [AOR]; 1.04, 95% confidence interval [CI]; 1.01-1.06) and ESBL production (AOR; 81.35, 95% CI; 17.76-372.53). Conclusion : The close relationship between ciprofloxacin resistance and ESBL production was documented in nosocomial K. pneumoniae bacteremia. Further epidemiological and molecular studies to determine factors and mechanisms involved in the relationship are needed.

      • 小腦 Purkinje細胞에 關한 組織學的 및 組織化學的 硏究

        盧永福,梁南吉,文正錫,鄭柱炫 순천향의과대학 1979 Journal of Soonchunhyang Medical Science Vol.2 No.1

        THe Purkinje cell is certainly one of the most spectacular nerve cells known. For many years all of Purkinje cell have been recongnized by the numerous authors. Yet unanimity on many doubtful points has not been reached, and our studies were carried out in an attempt to obtain the Knowledge of the neuro-anatomical research. We have studies on the Purkinje cellof various animal cerebellum by the his tological and histochemical method, and the results obtained are as follows; 1) The Purkinje cell bodies are arranged in a sheet on cell thick at the interface between the molecular and the granular layers in the vertebrates and birds. 2) The number of Purinje cells are local variations on the folium in each animals. 3) The size of the Purkinje cell in the cats are among the largest cellin the vertebrates. 4) All of the structural characteristics of the Purkinje cells can not found the variations between the vertebrates and birds.

      • KCI등재

        스모그 챔버에서 수분 반응에 의한 대기 에어로졸의 생성 및 성장

        김민철,배귀남,문길주,박주연 한국대기환경학회 2004 한국대기환경학회지 Vol.20 No.2

        Aerosol formation and growth by water vapor reactions were investigated in a 2.5-㎥ indoor smog chamber filled with the unfiltered ambient air. The relative humidity of test ambient air was elevated at 59~64% or 84~88% by adding water vapor. The aerosol number size distribution and the concentrations of O₃, NO, NO₂, and SO₂ were measured during the experiments. The O₃, and NO₂ gases were well reacted with the water vapor at high relative humidity of 84~88%, and the reaction rates of these gases seemed to be decreased at low relative humidity of 59~64%. The formation and condensational growth phenomena of ambient aerosols by water vapor reactions were observed in a Teflon bag, depending strongly on the initial particle size distribution. The water vapor reactions might be affected by the contents of oxidants produced by photochemical reactions under sunlight.

      • 도.토기의 과학적 분석-경상남도 도요지 출토 토기편을 중심으로

        홍종욱,조남철,황진주,문환석,Hong, Jong-Ouk,Cho, Nam-Chul,Hwang, Jin-Ju,Moon, Whan-Suk 국립문화재연구소 2001 保存科學硏究 Vol.22 No.-

        The scientific analysis and provenance study of potteries excavated from kiln site at Gyeongsang Nam-do were carried out using XRD, ICP-AES and NAA. We can summary the following Result :1. As a result of XRD analysis, it showed that soft potteries consisted of quartz, feldspar and clay minerals while hard potteries consisted of high temperature crystals such as mullite, tridymite, cristobalite.In case of firing temperature which are determined by XRD, potteries consisted of quartz, feldspar and clay mineral had very low firing temperature. While potteries having only cristobalite ranged above $1200^{\circ}C$.2. As a result of correlation analysis using trace element, the selected characteristic elements which was able to distinguish from each kiln site was Sm, Cs, Sc, Eu, Hf.3. Discriminant analytical showed that each kiln site were classified into 4-gruops;Kimhaeci Daesungdong, Hamangun Myosari, Changyounggun Yochori and one group mixed KimhaeciGuosandong, Kimhaeci Samgyeri. This suggests that there are no correlations between the raw materials used in each kiln sites except Kimhaeci Guosandong, Kimhaeci Samgyeri.

      • KCI등재

        Simultaneous Expression of Allogenic Class II MHC and B7.1 (CD80) Molecules in A20 B-Lymphoma Cell Line Enhances Tumor Immunogenicity

        Young-Ju Jang,Seon Young Nam,Moon-Sun Kim,Rho Hyun Seong,Yong-Su Park,Yong-Hoon Chung,Hee-Yong Chung 한국분자세포생물학회 2002 Molecules and cells Vol.13 No.1

        We expressed the allogenic class II MHC antigen and B7.1 (CD80) co-stimulatory molecule in A20 Blymphoma cells in order to test their efficacy as immuno- stimulating adjuvant agents in inducing tumorspecific immunity. The transduction of the allogenic IAb a and b chain genes into A20 cell resulted in a surface expression of the allogenic class II MHC molecules. The expression of the allogenic class II MHC antigen (I-Ab) in A20 cells enhanced the proliferation of T cells in a mixed lymphocyte tumor culture and in vitro cytotoxic T lymphocyte (CTL) generation against parental cells. The B7.1 gene, which is known to be a potent co-stimulatory molecule, was also transduced and expressed in A20 cells, either alone or in combination with I-Ab. The B7.1 transduction alone leads to a similar in vitro immune enhancing effect as I-Ab. When both the I-Ab and B7.1 genes were transduced, the in vitro immunostimulating capacity was further enhanced. Finally, we also tested the A20 cells that were transduced with I-Ab and/or B7.1 for their efficacy as preventive tumor vaccines in vivo. The results indicate that the A20 cells that express both the I-Ab and B7.1 have more potent vaccinating potential, compared to the cells that express only one of the molecules.

      • KCI등재
      • KCI등재

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