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        MSCT: AN EFFICIENT DATA COLLECTION HEURISTIC FOR WIRELESS SENSOR NETWORKS WITH LIMITED SENSOR MEMORY CAPACITY

        ( Murat Karakaya ) 한국인터넷정보학회 2015 KSII Transactions on Internet and Information Syst Vol.9 No.9

        Sensors used in Wireless Sensor Networks (WSN) have mostly limited capacity which affects the performance of their applications. One of the data-gathering methods is to use mobile sinks to visit these sensors so that they can save their limited battery energies from forwarding data packages to static sinks. The main disadvantage of employing mobile sinks is the delay of data collection due to relative low speed of mobile sinks. Since sensors have very limited memory capacities, whenever a mobile sink is too late to visit a sensor, that sensor`s memory would be full, which is called a `memory overflow`, and thus, needs to be purged, which causes loss of collected data. In this work, a method is proposed to generate mobile sink tours, such that the number of overflows and the amount of lost data are minimized. Moreover, the proposed method does not need either the sensor locations or sensor memory status in advance. Hence, the overhead stemmed from the information exchange of these requirements are avoided. The proposed method is compared with a previously published heuristic. The simulation experiment results show the success of the proposed method over the rival heuristic with respect to the considered metrics under various parameters.

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        Anti-Inflammatory Effect of Crude Momordica charantia L. Extract on 2,4,6-Trinitrobenzene Sulfonic Acid-Induced Colitis Model in Rat and the Bioaccessibility of its Carotenoid Content

        Nalan Gulsen Unal,Aysegul Kozak,Sibel Karakaya,Nevin Oruc,Burcu Barutc¸uoglu,Cagdas Aktan,Murat Sezak,Ahmet Omer Ozutemiz 한국식품영양과학회 2020 Journal of medicinal food Vol.23 No.6

        Momordica charantia L., known as bitter melon (BM), is a plant that belongs to the family Cucurbitaceae. Aims of this study are to investigate the anti-inflammatory effect of crude BM extract on 2,4,6-trinitrobenzene sulfonic acid (TNBS)-induced experimental colitis model in rat. It was also aimed to determine the content and bioaccessibility of carotenoids of BM. BM was purchased from local markets in Izmir, Turkey. Fruits of BM were lyophilized, powdered, and used in the experiment. Carotenoids were determined by high-performance liquid chromatography. To determine the bioaccessibility of β-carotene, in vitro digestion was performed. Wistar albino rats were divided into four groups: group A (BM+TNBS), group B (BM), group C (TNBS), and group D (control). BM solution was given 300 mg/(kg·day) for 6 weeks orally. Colitis was induced by 0.25 mL of a solution containing 100 mg/kg 5% (w/v) TNBS in 50% ethanol (w/v) intrarectally after 6 weeks. After sacrification, macroscopic and microscopic evaluations were performed. Myeloperoxidase, cytokines levels (interleukin-17 [IL-17], TNF-alpha, and interleukin-10 [IL-10]) were measured in serum and colonic samples by ELISA test. Institutional Animal Ethics Committee approval was obtained. Total carotenoid content of BM was determined 11.7 mg/g dry weight as β-carotene equivalents. Bioaccessibility of total carotenoids was determined as 2.1% with in vitro digestion. Pretreatment with crude BM extract significantly reduced weight loss, macroscopic, and microscopic colitis damages in colonic samples (P = .000), (P = .015), and (P = .026), respectively. Serum anti-inflammatory cytokine IL-10 increased significantly in both treatment groups (P = .000). BM is a rich source of carotenoids, but the bioaccessibility of its carotenoids is low. This study displays that BM has protective anti-inflammatory effects on TNBS-induced colitis.

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