만성 신부전을 동반한 Laurence Moon-Bardet Biedl 증후군 1례

박래경,이동환,문철,김은미,Park Lae Kyong,Lee Dong Hwan,Moon Chul,Kim Eun Mi 대한소아신장학회 1998 Childhood kidney diseases Vol.2 No.2

The Laurence Moon-Bardet Biedl syndrome is characterized by obesity, mental retardation, visual impairment with retinitis pigmentosa, polydactyly, hypogonadism and renal manifestations. We experienced an 11 years old female with Laurence Moon-Baret Biedl syndrome associated chronic renal failure. She was diagnosed to have LMB syndrom according to the clinical manifestations of polydactyly on hands and feet, mental retardation, obesity, retinitis pigmentosa and chronic renal failure. She is on maintenance hemodialysis now.

김남천 소설의 어휘 사용 양상에 대한 계량적 연구

문한별(Han Byoul Moon),김일환(Il Hwan Kim) 한국현대소설학회 2011 현대소설연구 Vol.- No.48

This paper aims to investigate characteristics of use of lexical items in Kim, Namcheon`s novels based on quantitative and statistical approach. It is well known that trends of Kim`s novel have seriously changed after KAPF was dismissed. However there are few researches how this kind of changes can be affected in his novels concretely. It is expected that quantitative approaches on Kim`s novels are able to overcome this kinds of limit. Especially in this paper, in order to analyze his novels, first, we developed his 17 representative novels to raw corpus, and then annotated linguistic information, part-of-speech to the corpus. From the annotated corpus, we can get the frequencies of words(nouns) by works and part-of-speeches. However even most frequent words in the text are not always meaningful to analyze the text. So statistical verification as a t-score must be applied in the process of extracting keywords. As a result we are able to find some keywords in 17 texts explicitly and trends of Kim`s novels are explained by year and work in a successful way.

The prediction of the tooth size in the mixed dentition for Korean

Moon, Sung-Hwan,Kim, Seong-Oh,Yu, Hyung-Seong,Choi, Byung-Jai,Choi, Hyung-Jun,Lee, Jae-Ho 大韓小兒齒科學會 2006 대한소아치과학회지 Vol.33 No.2

이번 연구의 목적은 혼합치열기 아동에서 미맹출된 견치와 소구치의 크기를 예측하는데 있어서 한국인에 맞는 방정식을 만들기 위함이다. 미맹출 치아의 크기를 예측하는 것은 혼합치열기 교정 진단과 치료계획 수립에 있어서 매우 중요하다. 미맹출된 견치와 소구치 크기를 예측하는 방법은 몇가지가 있지만 그중에서도 가장 흔하게 쓰이는 것이 모이어의 예측표와 다나카와 존스턴의 방정식이 있다. 하지만 그것들은 백인을 위해서 제작된 것이고 치아 크기는 인종에 따라서 다르다고 알려져 있다. 이번 연구에서는 치아크기를 측정하여 하악 영구 절치의 크기 합과 견치 및 소구치의 크기 합 사이의 상관관계를 구하고 회귀방정식을 이용해서 한국인에 맞는 예측표를 만들었다. 연세대학교 치과대학에 재학중인 178명의 한국 학생(남 108명, 여 70명, 평균연령 21.63)을 대상으로 실험하였다. 영구치의 근원심 폭경을 석고모형상에서 calipers를 이용해서 측정하였다. 성별간의 치아 크기는 차이가 있었다(p<0.05). Correlation coefficient는 0.57에서 0.64의 범위였고, standard errors of the estimates 는 여성에서 0.6으로써 남성보다 우수하였다. r^(2)값은 0.27에서 0.41의 범위를 나타내었다. Estimating the size of unerupted teeth is an essential aspect of orthodontic diagnosis and treatment planning in the mixed dentition. Several methods were introduced and used for the prediction. The most common methods among these would be Moyers probability chart and Tanaka and Johnston equations. These are currently used widely, but they were developed for Caucasians. Because there are clear racial differences in teeth size, the objectives of this study were to produce correlation coefficients between the combined mesiodistal widths of the permanent mandibular incisors and those of the canines and premolars for each quadrant, and prediction tables with regression equations, specifically for Korean. 178 young adults (70 women, 108 men, mean age 21.63 years) were selected from the College of Dentistry, Yonsei University, Seoul, Korea. The mesiodistal crown diameters of the permanent teeth were measured with calipers. Significant sexual dimorphism was found in tooth sizes. The correlation coefficients between the total mesiodistal width of the mandibular permanent incisors and those of the maxillary and mandibular canines and premolars were found to be between 0.52 and 0.64. The standard error of the estimatation was better (0.60) for women and the r^(2) values ranged from 0.27 to 0.41 for both sexes, Prediction tables were prepared for Korean. This study showed larger canine and premolar diameters than Tanaka and Johnston's and Moyers' studies which might be due to the racial differences. Further investigations with a larger sample size will be needed for more representative data on the Korean population.

두부 손상이 골절 칭 촉진 시동물 모델 및 유전자 발현 분석

김경희,김학선,문성환,김향,권언해,이환모,박희완,한수봉,문은수 대한정형외과연구학회 2003 대한정형외과연구학회지 Vol.6 No.2

방사선치료 조사영역 내에 발생한 설암 환자에서 입체조형방사선치료 경험 : 증례보고

조문준,장지영,김기환,김병국,송창준,김준상,김재성 충남대학교 암공동연구소 2003 암공동연구소 업적집 Vol.3 No.

Objectives : We report an interim result of conformal radiotherapy in a patient with early stage cancer at the base of the tongue, which developed in a previously irradiated area. Materials and Methods : A 64-year-old male patient was diagnosed with T4NOMO supraglottic cancer. He received 72Gy of radiation therapy from 21 November 1988 to 24 February 1989. He had local failure and underwent a salvage total laryngectomy on 28 August 1989. Subsequently, he did well. In early 1999, he suffered from throat pain. He had a 2.5cm ulcerative mass at the base of his tongue, in the area that had been irradiated previously. Biopsy showed squamous cell carcinoma. After workup, he was diagnosed with base of tongue cancer with T2NOMO. Surgery was not feasible because the morbidity was not acceptable. Since it was difficult to re-irradiate the area with a curable dose using conventional 2D radiation therapy with an acceptable morbidity, we decided to try conformal radiotherapy. We used 7 static beam ports with field sizes from 7×6.4 to 8×8㎠, using 6 and 10MV photons. The fractionation regimen was 1.8Gy, 5 times per week. He received 64.8Gy in 36 fractions from 9 April 1999 to 1 June 1999. Results : In the 21 months since radiotherapy, the patient has not experienced any acute or chronic complications, such as xerostomia. He experienced relief of pain shortly after the start of radiotherapy, showed a complete response, and is still doing well. Conclusion : Conformal radiotherapy can be used to treat cancer that develops within a previously irradiated field, with curative intent.

척추관 협찬증 환자 진료 프로세스 개발

이환모,김호중,김긍년,안풍기,천자혜,김양수,신혜선,김인숙,정혜경,김영아,채형기,박인영 한국의료QA학회 2009 한국의료질향상학회지 Vol.15 No.2

연구배경: 수술적 치료가 필요한 척추관협착증 환자들은 주로 60세 이상의 고령환자로장기간의 입원 시 기회 감염의 증대와 불필요한 의료비의 증대를 가져오게 되며, 수술후환χ}들의 재원일수의 증가는병원의 병상가 동률을감소시키고, 전공의에게는불필요한 업무를 증가시킨다. 연구목적: 비용·효과면에서 최적화된 진료지침의 개발은 불필요한 의료비의 감소및 Hospital Induced Complication을 줄여 환자만족도를증진시킬 수 있으며, 각 환자에 대한전공의 업무를 줄일 수있다. 의료기관: 서울특별시에 소재한 2,075병상의 종합전문 요양기관 연구방법: 정형외과및 신경외과의 척추관협착증환자 의 처방을 비교하여 최적의 표준진료지침을 개발하고 최종적으로 CP Master Program (EMR 프로그램)에 입력하여 환자에게 적용하였다. 연구결과': CP 적용전, 후비교를통해 재원일수는 3.8일 이 감소하였으며, 이에 따라 병상가동률 및 진료수익이 증가했으리라고 예상되며 현재 비교검토중이다. 또한,CP 개발및 CP Master Program의 사용을 통한 전공의 업무감소에 대해 검토하고 있다.

방사선치료 조사영역 내에 발생한 설암 환자에서 입체조형방사선치료 경험 : 증례보고

조문준,장지영,김기환,김병국,송창준,김준상,김재성 충남대학교 암연구소 2003 암연구소 업적집 Vol.3 No.-

Objectives : We report an interim result of conformal radiotherapy in a patient with early stage cancer at the base of the tongue, which developed in a previously irradiated area. Materials and Methods : A 64-year-old male patient was diagnosed with T4NOMO supraglottic cancer. He received 72Gy of radiation therapy from 21 November 1988 to 24 February 1989. He had local failure and underwent a salvage total laryngectomy on 28 August 1989. Subsequently, he did well. In early 1999, he suffered from throat pain. He had a 2.5cm ulcerative mass at the base of his tongue, in the area that had been irradiated previously. Biopsy showed squamous cell carcinoma. After workup, he was diagnosed with base of tongue cancer with T2NOMO. Surgery was not feasible because the morbidity was not acceptable. Since it was difficult to re-irradiate the area with a curable dose using conventional 2D radiation therapy with an acceptable morbidity, we decided to try conformal radiotherapy. We used 7 static beam ports with field sizes from 7×6.4 to 8×8㎠, using 6 and 10MV photons. The fractionation regimen was 1.8Gy, 5 times per week. He received 64.8Gy in 36 fractions from 9 April 1999 to 1 June 1999. Results : In the 21 months since radiotherapy, the patient has not experienced any acute or chronic complications, such as xerostomia. He experienced relief of pain shortly after the start of radiotherapy, showed a complete response, and is still doing well. Conclusion : Conformal radiotherapy can be used to treat cancer that develops within a previously irradiated field, with curative intent.

Lithium Fluoride의 結晶 構造

金彰鎭,金文執,梁俊默,徐日煥 충남대학교 1985 忠南科學硏究誌 Vol.12 No.1

The crystal structure of lithium fluoride, LiF, has been determined by X-ray (Cu K_α radiation) powder diffraction method. The crystal is face-centered cubic, space group F4/m3￣2/m, with unit cell dimensions a=4.0272(2)Å, V=65.31(1)Å^3, z=4 and D_c=2.64g/㎤. The structure was solved by graphical method using nine powder diffractometer intensity data for LiF and Nelson-Riley function was used for the cell dimension refinement. The experimental and theoretical integrated intensities of the reflecting planes are in good agreement with each other. The LiF crystal is aggregates of positive and negative ionic atoms with interatomic distance 2.0136(1)Å which shows the ionic bond between Li^+ and F^-. Each lattice point is occupied by a Li^+-F^- ion pair in the same orientation and the coordination number is six. Thus the LiF structure is exactly same as NaCl.

생물학적 유동층을 이용한 정화조유출수의 질소성분 제거

김환기,권문선 동아대학교 환경문제연구소 1986 硏究報告 Vol.9 No.3

본 연구는 정화조 유출수의 질소성분 제거에 관한 기초적 연구로서 주로 암모니아성 질소제거를 위한 실험적 결과에 관한 내용이다. 실험에 사용한 시료는 정화조 유출수와 유사한 합성폐수를 사용하여 그 처리가능성을 구명한 후 실제 정화조 유출수를 사용하여 비교하였고, 질산화 반응이 단계적으로 일어날 것을 고려하여 4단계 생물학적 유동층을 고안 하였으며, 이 반응기를 이용하여 질소제거 가능성을 검토하였다. 그 결과 순환비 변화에 의한 유기물 제거는 초기단계에서 80% 정도 였으며 질산화 반응은 후기단계에서 90% 이상의 암모니아성 질소가 제거되었다. 체류시간에 따른 유기물은 1단계에서 대부분 진행되어 85%이상 제거되었으며 질산화 반응은 3, 4단계에서 90%이상의 암모니아성 질소가 제거되었으며, 이때 적정순환비 및 체류시간은 각각 30과 7시간이었다. 합성폐수와 실제 정화조 유출수의 NH₄^(+)-N 제거와 NO₃^(-)-N 생성 효율을 얻기 위한 실험에서 NH₄^(+)-N 1㎎/ℓ 제거에 합성폐수는 NO₃^(-)-N 0.95㎎/ℓ가 생성되었고 실제 정화조 유출수는 0.82㎎/ℓ NO₃^(-)-N 이 생성되었다. 또한 유동층 반응기에서 질산화 반응의 동력학적 계수를 구하였다. This paper is a basic study of the experimental results for the treatment of ammonianitrogen in the septic tank effluent. The substrates in this experiment are actual septic tank effluent and synthetic waste-water which is similar to septic tank effluent containing a considerable amount of nitrogenous component. Experiments were conducted for organic removal and nitrification using various recycle ratio and hydraulic retention time at each stage. The results obtained show that organic removal rate was above 80% in the 1st and 2nd stage, but as nitrification process was proceeded, above 90% of ammonia-nitrogen was removed in the 3rd and 4th stage. In these cases, the recycle ratio and HRT were found 30 and 7 hrs respectively. In the relation of NH₄^(+)-N removal to NO₃^(-)-N formation in the synthetic waste-water and septic tank effluent, when 1㎎/ℓ of NH₄^(+)-N was removed, NO₃^(-)-N formations were 0.95 ㎎/ℓ and 0.82㎎/ℓ respectively. And kinetics of nitrification using Biological Fluidized Bed was discussed also.

급성 일산화탄소 중독증 환자의 임상적 고찰

김문환 대한응급의학회 1995 대한응급의학회지 Vol.6 No.1

We experienced two hundred sixty six patients of acute carbon monoxide poisining admitted to Jang Sung hospital through emergency center from January 1987 to December 1994, and they were clinically analyzed and evaluated including delayed postanoxic encephalopathy. Mean age of the patients was 38.7±18.3 years and the ratio of male to female was 1:1.5. Mental state was alert mostly(50.7%), and their chief complaints were headache, nausea, and dizziness. The more disturbed mental state, the more decreased arterial pH and PaCO₂, which may be the result of metabolic acidosis. The early laboratory findings in patients were ; Ieukocytosis 57.5%, increased hematocrit 23.3%, hyperglycemia 18%, increased GPT 14.7%, increased BUN 5.3%, glucosuria 19.2%, and proteinuria 12.0%. The abnormal electrocardiography findings(24.8% of 266 cases) were sinus tachycardia, T wave inversion, sinus bradycardia, STT change, tall T wave(>10mm), low voltage and incomplete RBBB with incidence and thirteen cases have two or more abnormal findings. The incidence of delayed postanoxic encephalopathy was 6.0% and two cases died in the period of admission because of multiorgan failure and respiratory failure in each cases. We concluded that initial treatment of the carbon monoxide poisoned patient who cardiopulmonary function was preserved are hyperbaric oxygen theraphy and conservative management of cerebral edema. Therefore, we suspect good clinical result and prognosis even in coma patients.