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      • 혈액 투석 환자에서 중심정맥 협착에 대한 스텐트 삽입술 : Wallstent Placement

        임대승,노상필,이유선,정승현,김보영,이정우,강정아,김정희,이민수,정준용,최시완,정진옥,성인환,이강욱,신영태 충남대학교 의과대학 의학연구소 2002 충남의대잡지 Vol.29 No.1

        Stenosis of central vein is a common complication arising after percutaneous subclavian vein catheter insertion performed for temporary vascular access in chronic renal failure patients undergoing hemodialysis. There are several treatment methods for the condition like percutaneous angioplasty(PTA), stent insertion, and surgery, but recent trend is toward PTA and stents. Among the patients diagnosed with chronic renal failure from March 1993 to May 2002 and undergoing hemodialysis through AV fistula, the 14 Patients in whom central vein stenosis arose were selected for the study. A total of 28 percutaneous interventions(5 PTA and 23 stent placement) were performed, and restenosis rate and the time taken till the restenosis in de novo lesions and instant lesions were compared. All 28 cases were operated successfully. The 14 cases that received both anigioplasty and stent placement initially. (de novo lesion : 14 cases), Among the 10 cases with de novo lesion that followed up more than 1 year, 3 cases are currently undergoing hemodialysis without restenosis, and the remaining 7 cases have recurred stenosis with the mean time to restenosis of 10.9 months. In the 7 cases in whom stenosis recurred, 11 interventions were done(instent lesion: 11 cases). 4 of these were using only ballon angioplasty with 100% restenosis rate and the mean time of 3 months until restenosis. The remaining 7 cases were using both balloon angioplasty and stent placement, also with 100% restenosis rate but with the mean time of 12 months until restenosis, which was later than the group receiving only balloon angioplasty. In treating the patients with central vein stenosis, stent placement seems to be more advantageous over PTA in terms of restenosis rate and the mean duration of patency. In the case of instent lesion, inserting the stent for the second time after stenosis recurred lengthened the duration of patency compared to performing balloon angioplasty alone.

      • 형질전환 제초제저항성 벼 밀양 204호의 농업적 특성

        정응기,이기환,원용재,박향미,전남수,최준호,구연충,한창덕,은무영,김태산,남민희 Plant molecular biology and biotechnology research 2005 Plant molecular biology and biotechnology research Vol.2005 No.

        This study was conducted to investigated the major characteristics of genetically modified rice of "Milyang 204" originated from Dongjinbyeo compared to a non-transgenic rice varieties Dongjinbyeo and Junambyeo. Basta resistant transgenic rice lines carrying bar gene produced by the Yeongnam Agricultural Research Institute were evaluated for their agronomic characters. The transgenic Japonica rice of "Milyang 204" showed inferior phenotypic traits compared to a non-transgenic rice variety Dongjinbyeo and Junambyeo. On the basis of UPOV (Union Internationale Pour la Protaection des Obtentions Vegetables) and NSMO(National Seed Management Office) the transgenic "Milyang 204" showed difference in some traits out of some agronomic traits, such as leaf color, angle of flag leaf, number of spikelets, culm length, white core and white belly compared to the nontransgenic varieties rice.

      • KCI등재
      • 여수국가산업단지 인근 지역 대기오염물질 농도에 영향을 미치는 요인분석

        김민영,변정훈,이영훈,이건영,한지은,이예림,임지현,장봉기 순천향대학교 기초과학연구소 2022 순천향자연과학연구 논문집 Vol.28 No.1,2

        Eight monitoring stations in the Yeosu National Industrial Complex will determine the concentration of air pollutants measured every hour in 2019, analyze what factors affect them, and how they correlate with the air pollutant measurements. Six air pollutants (SO2, NO2, O3, CO, PM-10 and PM-2.5) measured at eight monitoring stations around Yeosu National Industrial Complex (Seogang-dong, Wolnae-dong, Munsu-dong, Yeocheon-dong, Deokchung-dong, Hwayang-myeon, Yulchon-myeon, Samil-dong) the measurement data for each hour of the year were downloaded to analyze the concentration by weather condition, time zone, season, separation distance from Yeosu Industrial Complex, and separation distance from Gwangyang Industrial Complex. SO2, NO2, and CO concentrations were significantly higher in winter, significantly lower in summer, and O3, PM-10, and PM-2.5 concentrations were significantly higher in spring. SO2, CO, PM-10, and PM-2.5 concentrations were significantly higher between 10 a.m. and 12 p.m., NO2 concentrations were significantly higher between 7 a.m. and 9 a.m., and O3 concentrations were significantly higher between 13 p.m. and 15 p.m.(p<0.001). The concentration of air pollutants (SO2, NO2, CO, PM-10, PM-2.5) excluding O3 was found to have a negative (-) correlation with weather condition, and in the case of O3, it was found to have a positive (+) correlation with PM-10, PM-2.5, temperature and wind speed. It was confirmed that the concentration of air pollutants emitted from the Yeosu National Industrial Complex differs depending on the season, time and distance to the industrial complex. This study aims to establish measures to minimize health damage to residents living relatively close to the industrial complex and contribute to the establishment of management and response measures according to the properties of substances to reduce the concentration of air pollutants in the future.

      • 컴퓨터 작업 시 의자 등받이 위치가 근육 활성도에 미치는 영향

        김민우,변승진,이경은,정소영,조주영,최원자,최찬양,김경 대구대학교 특수교육재활과학연구소 2011 再活科學硏究 Vol.29 No.1

        이 연구는 컴퓨터 작업시 의자 등받이 위치가 근육활성도에 미치는 영향을 알아보기 위해 36명의 근골격에 문제가 없는 성인 남녀가 참가하였으며 대상자들은 등받이가 뒤에 있는 의자와 등받이가 없는 의자, 등받이가 앞에 있는 우리들 의자를 무작위로 배정하고 동일한 컴퓨터 작업을 실시하게 하였다. 실험 중, 표면근전도기를 사용하여 의자에 따른 위등세모근, 머리널판근 그리고 척주세움근의 근활성도 변화를 측정하였다. 이 연구의 결과를 종합해보면 등받이가 앞에 있는 의자는 허리 근육의 부담을 줄이지만 목근육에 부담이 늘어나고 등받이가 뒤에 있는 의자와 없는 의자는 허리근육에는 다소 무리가 가지만 목근육에는 부담이 덜하다는 것을 알 수 있었다. 이러한 결과로 환자의 증상에 다라 컴퓨터 작업을 하는 동안 의자 등받이의 위치를 조절하여 치료에 도움이 될 수 있다고 생각되어진다. Objective : In this study, we checked and observed people's change of body muscle and muscle activity who do computer work on different chairs. We set three kind of chairs which one is a stool and another one is the back is fixed, and the other one is the back is fixed in front of chair. Subject : Accounting for 36 health men and women, we divided these people to 3 groups and put them on the three cases(position 1, position 2, position 3). We measured muscle activity of upper trapezius, Splenius Cervics, Erector Spinae from the groups by using surface electromyogram system. Methods : The standard of the electromyogram was 'reference voluntary contraction', and we carried out 'one way anova' to compare muscle activity of three groups. Results : In position 1, reference voluntary contraction of upper trapezius muscle activity was 123.2821%, Splenius Cervics was 141.7526%, and Erector Spinae was 254.5233%. In position 2, reference voluntary contraction of upper trapezius muscle activity was 132.9395%, Splenius Cervics was 141.7526%, and Erector Spinae was 246.6540%. In position 3, reference voluntary contraction of upper trapezius muscle activity was 190.6487%, Splenius Cervics was 270.2332%, and Erector Spinae was 182.1021%. Both upper trapezius and Splenius Cervics muscle activity of position 3 group was higher than the others groups. In position 1 group, Erector Spinae muscle activity was hight than the other groups. And either was position 2 group's(p<0.05). Conclusion : Therefore the chair which is the back is fixed in front is more comfortable for waist muscle but it's not good for neck. And the other chairs are better in waist muscle but not in neck muscle. So far, when we do a computer work, it's prefer to sit on the group 1&2's chairs to reduce neck muscle's stress and sit on group 3's chair to reduce waist muscle's stress.

      • 사람 비만세포주에서 Clozapine과 Fluoxetine에 의한 케모카인 및 케모카인 수용체의 상이한 발현

        유영민,김종우,조정제,임강현 대한생물치료정신의학회 2001 생물치료정신의학 Vol.7 No.2

        Objectives : It has been suggested that the immune system has a role in the pathophsiology of neuropsychiatric diseases. There are some reports that clozapine and fluoxetine affect on cytokine networks. Recently, it has been known that chemokines have chemotactic effect, and modulate a number of biological responses including the process of inflammation and the maintenance of CNS homeostasis. In the present study, we investigated the effect of clozapine or fluoxetine on the expression of chemokines and their receptors. Methods : Human mast cells(HMC-1) was incubated with phorbol myristate acetate(PMA, 100ng/㎖) and calcium ionophore A23187(350ng/㎖) for 3 hours. Colzapine(10^-7M) or fluoxetine(10^-7M) were pretreated for 1 hour. RT-PCR was performed for the detection of expression of various chemokines and chemokine receptors. Results : after treatment of clozapine, the expression of MCP-1, MIP-1β, CCR3,CXCR2, CXCR3 and CXCR4 were lower than the PMA/Ca ionophore-treated group, while the expression of MIP-1α, RANTES and IL-8 were not changed. However, fluoxetine was not affected the changes of expression of various chemokines and chemokine receptors. Conclusion : This result indicates that clozapine may affect on the expression of chemokines and chemokine receptors. Therefore, this study could, in part, provide the important basic data on the explanation of side effects of clozapine, such as fever and pancreatitis.

      • 동결속도제어에 의한 동결건조기 성능개선 및 동결건조품의 물리적 특성에 관한 연구

        김정한,신영우,김민용,박기원,강정길 여수대학교 1998 論文集 Vol.12 No.2

        It is essential to establish optimum operating condition in order to decrease freeze drying time and energy cost on freez-drying process. In this study freezing point, thermal condutivity and permeability of vapour on freeze-drying process of coffee solution were measured. The results of abtained were summarized as follows: 1) thermal conductivity were not affected by freezing rate but were increased with increasing concentration of coffee solution 2) permeability of vapour was increased with decreasing freezing rate and concentration of coffee solution These result suggested that freezing temperature of freeze-drying material must be determined through measuring freezing point of material for the purpose of saving energy cost and ahortening freezing time 1) thermal conductivity depend on solids porosity and was not concerned with size and shape of pore 2) permiability decrease with lowering freezing temperature beacuse radius of freeze drying layer was smaller and permiability decrease with higher concentration because of porosity was decreased

      • 비스판 변이주인 Bacillus polyfermenticus KD21의 주요 생균제 특성

        정민용,정황영,하정욱,백현동 慶南大學校 附設 基礎科學硏究所 2002 硏究論文集 Vol.16 No.-

        Bacillus polyfermenticus SCD which is commonly called as Bispan strain are being used for functional foods using the treatment of long-term intestinal disorders, since the live strains in the form of active endospores can successfully reach the target intestine in both humans and animals. B. polyfermenticus KD21 was obtained for higher sporulation through the NTG mutagenesis. The cells of B. polyfermenticus KD21 was treated for 24 h in artificial bile after incubation for 2 h in artificial gastric juice and final number of the strain was reached to around 10^8 CFU/㎖. In test of API ZYM kit, β-glucuronidase or β-glucosidase were not produced by B. polyfermenticus KD21. B. polyfermenticus KD21 was resistant to antibiotics such as nisin, tetracyclin, streptomycin, and rifamycin. B. polyfermenticus KD21 was shown to inhibit the growth of Listeria monocytogenes ATCC 19111 completely within 24 h of incubation, which indicates its bactericidal nature.

      • 경주 남리사지에 사용된 석재의 암석학적 특성과 원산지 해석

        이찬희,정연삼,정민호,이명성,김영택 공주대학교 문화재보존과학연구소 2004 문화재과학기술 Vol.3 No.1

        이 연구는 경주 남리사지에 이용된 석재를 대상으로 암석의 성인적 분류, 광물 및 지구화학적 특성을 검토하여 석재의 기원지 추정과 고고지질학적 의미를 해석한 것이다. 남리사지에서 출토된 암석은 5종의 화강암질암 (알카리 화강암, 흑운모 화강암, 미문상 화강암, 등립질 화강암, 홍장석 화강암), 세립질 퇴적암 (셰일, 미사암), 호온펠스, 옹회암질암, 염기성 맥암 등이 있다. 이 중에서 서탑에 이용된 암석은 유백색의 중립질 알카리 화강암과 담홍색의 흑운모 화강암이 주류를 이룬다. 각 석재들의 대자율 값은 흑운모 화강암이 4.94~7.59 (평균 6.47)로서 제일 높았으며 미문상 화강암이 0.86~1.54 (평균 1.13)로 제일 낮았다. 알카리 화강암은 3.51, 홍장석 화강암이 5.88, 등립질 화강암이 4.89로서 분화경로와 산출상태에 따라 조금씩 다른 값을 보였다. 이 화강암류는 화학조성으로 볼 때, 거의 동일한 마그마 기원의 칼크-알카리 계열 화강암 영역에 해당된다. 이 석재의 화학적 풍화지수와 풍화 잠재지수는 각각 49.87~61.64와 4.12~8.46 범위로서, 현재 암석이 화학적 풍화작용이 왕성하게 발생하는 정도는 아니나 풍화잠재력은 매우 높은 것으로 나타났다. 이 화강암질암의 암석학적 및 지구화학적 특징으로 볼 때, 이들의 성인적 유형은 남산 일대에 분포하는 화강암과 동일하다. 따라서 남리사지의 석조문화재 건축에 사용된 석재는 현지에서 재료를 구하고 현장에서 제작한 자급자족형 석재와 수계의 상류지역에서 도입된 외래형 석재가 공준하고 있는 것으로 해석된다. 자급형 석재가 현지의 원료를 이용한 것은 확실하나 어느 지역에서 채석하여 어디서 가공을 하였는지는 불분명하다. Rock properties around the Namri temple site was studied source area and archaeogeological interpretations based on petrology, mineralogy and geochemistry. Excavated rocks from the area composed of granitic rocks (alkali granite, biotite granite, micrographic granite, eqigranular granite, pink feldspar granite), fine grained sedimentary rocks (shale and siltstone), hornfels, tuffaceous and basic dyke rocks. Almost rock materials of the west pagoda made of white medium grained alkali granite and biotite granite. As the magnetic susceptibility (MS), biotite granite ranges from 4.94 to 7.59 (mean 6.47), and micrographic granite is lowest value of 0.86 to 1.54 (mean 1.13). The mean MS values revealed that alkali granite = 3.51, pink feldspar granite = 5.88, eqigranular granite = 4.89, which are little variatins because of differentiation process and field occurrences. In the geochemical data, the granitic rocks represent a comagmatic calc-alkali series granite. The values of WPI and CIA for rock properties from the Namri temple site range from 49.87 to 61.64 and 4.12 to 8.46, respectively, which values don't going active weathering right now, but weathering potential represents very high. On the basis of petrology and geochemistry of the rock properties from the Namri temple site, the genetic types are the similar as those of the Namsan granite. Therefore, the using rocks of the Namri temple site suggested that domestic type rock properties getting material in the actual place and making in situ, and foreign type rock properties getting from the upstream area are coexisted. Domestic types are sure of making the actual place material, but unclear where is a quarry and working.

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