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      • 저장조건에 따른 단감 '부유'의 품질변화

        안광환,강정한 Institute of Genetic Engineering Changwon National 1999 Gene and Protein Vol.3 No.1

        This study was carried out to investigate the causal factors affected to skin browning of 'Fuyu' Persimmon during storage. The storage experiments were done under CA(Controlled Atmosphere), MA(Modified Atmosphere) and CA+MA. The results were as follows ; 1. The skin browning was occurred in CA+MA-storage after 50 days of storage, and at this point, O₂level was bellow 1%, while CO₂ level was about 10%. 2. 'Fuyu' Persimmon under CA-storage was softened, while the content of glucose and fructose were content increased, the content of sucrose was decreased after 100 dags of storage.

      • 초음파 센서를 이용한 무궤도 반송차의 위치 및 방향제어

        안중환,김화영,임한석,김동신 부산대학교 공과대학 1989 硏究報告 Vol.38 No.-

        The system that could control a position and a direction of a vehicle by means of supersonic sensors was developed. It is composed of a microcomputer, two couples of supersonic sensor, a vehicle, a power supply and interfaces. Two senders are located at a distance on the vehicle and two receivers are located at two reference coordinate points. Supersonic propagation time from each sender to each receiver was conveniently measured in terms of the repeating number of a short machine language program. Experimental results showed that a repeating number was nearly linear with a corresponding distance. Using four measurements, the present position and direction of the vehicle were calculated .And the amounts of distance to be moved and angles to be rotated to get a destination position and direction were calculated. These data were used for controlling the vehicle driven by two wheel step. Judging from movement tests, the controllability and the accuracy of position an direction of a vehicle using supersonic sensors were quite satisfactory.

      • SCISCIESCOPUS

        Reconstruction of Rabbit Corneal Epithelium on Lyophilized Amniotic Membrane Using the Tilting Dynamic Culture Method

        Ahn, Jae-Il,Lee, Doo-Hoon,Ryu, Yang-Hwan,Jang, In-Keun,Yoon, Mun-Young,Shin, Youn Ho,Seo, Young-Kwon,Yoon, Hee-Hoon,Kim, Jae-Chan,Song, Kye-Yong,Yang, Eun-Kyung,Kim, Ki-Ho,Park, Jung-Keug Blackwell Publishing Inc 2007 Artificial Organs Vol.31 No.9

        <P>Abstract: </P><P>Rabbit corneal epithelium was reconstructed using tilting dynamic culture with a self-manufactured, amniotic membrane (AM) supporter and a lyophilized amniotic membrane (LAM). Rabbit corneal epithelial (RCE) cells were cultured and cryopreserved after isolation from the limbus. The second- and third-passage RCE cells were plated onto the epithelial side of the LAM of Ahn's AM supporter. Two days later, the air–liquid interface culture was maintained with third-passage RCE cells for 6 days and second-passage corneal epithelial cells for 9 days. The average viability of thawed RCE cells, assessed using trypan blue dye exclusion, was 77.42%. The reconstructed corneal epithelium was characterized by histological (hematoxylin and eosin) and immunohistochemical staining (proliferating cell nuclear antigen) for light microscopy, and by reverse transcriptase-polymerase chain reaction, glucose assay, and transmission electron microscopy. The basal layer of the reconstructed corneal epithelium was well formed, and the epithelium was tightly constructed due to the increase in cell proliferation and differentiation caused by the tilting dynamic culture, as opposed to static culture. Tilting dynamic culture was useful for the reconstruction of the epithelium using easily damaged epithelial cells and resulted in more stratum cell layers. Moreover, cytokeratin (CK3) mRNA expression in tilting dynamic cultured third-passage RCE cells seeded onto AM was greater than in static cultured third-passage RCE cells. The morphology of the reconstructed corneal epithelium on LAM by tilting dynamic culture for 9 days resembled that of the skin epidermis. This was thought to be because the tilting dynamic culture not only accelerated the proliferation and differentiation of cells by physical or mechanical stimulation, but also ensured that the supply of medium was delivered to the basal cells more efficiently. Thus, the reconstruction of the corneal epithelium using LAM and tilting dynamic culture was considered to be a good in vitro model for autologous or allogeneic transplantation of corneal epithelium and skin epidermis in patients with damaged epithelia. </P>

      • KCI등재

        최적 금형연마 가공을 위한 센서 정보 통합 전문가 시스템 개발

        안중환,김화영,申云峰,정해도,조규갑 韓國工作機械學會 2000 한국생산제조학회지 Vol.9 No.1

        This paper presents a polishing expert system integrated with sensor information which can modify the polishing sequence and conditions initially determined by the system depending on the on-site polishing status. A practical system using AE sensor to detect the on-line polishing status is developed for the rotational polishing and the smoothly curved sur-face. Database and knowledge base for polishing processes are established by using the results of experiments and also expert's experience. Evaluations are performed for a die of headlight lamp by using both the sensor integrated expert sys-tem and the expert system without sensor. The test results show that the sensor integrated expert system provides more optimal polishing conditions since the proposed system takes advantage of the on-line sensor information.

      • KCI등재
      • 수포성 유천포창 및 후천성 수포성 피박리증에서 혈청과 소변 IgG 자가항체의 역가에 관한 연구

        박정환,안인숙,이창우 한양대학교 의과대학 2002 한양의대 학술지 Vol.22 No.2

        The immunoglobulins can be detected in the urine in normal people without any renal disease. According to recent articles, it is known that autoantibodies of IgG, which share the identical antigenic specificities with the serum autoantibodies, targeting some nuclear antigens and cutaneous basement mambrane zone antignes could be detected in the urine in patients with systemic lupus erythematosus and autoimmune bullous diseases. The author examined the urine for the detection of autoantibodies in patients with autoimmune bullons diseases and compared the titers of IgG autoantibidies in the serum and urine in each patient. Six patients were included in this study. They were 2 patient-guoups of bullous pemphigoid (BP) and epidermolysis bullosa acqusita (EBA). Each group consisted of 3 patients having circulating autoantibodies in the serum. For a semi-quantitation of the IgG autoantibodies in the serum and urine specimens in each group,l the indirect immunofluorescent (IIF) tests were performed. All six patients showed positive results of autoantibidies in serum specimens. In each patient-group, IgG autoantibodies were detected in the urine of all patients at low titers. It appeared that cases with high antibody titers in the sera may deliver more frequent positive findings for the urine autoantibodies. The IIF test of the urine could be tried for a diagnosis of autoimmune bullous diseases in some patients with active autoimmune bullous dermatoses, espacially in cases with certain difficulties in collecting serum samples.

      • 수입 외국산 모발세정용 화장품의 중금속 농도에 관한 연구

        문정아,문덕환,박명희,안진홍,김종은,손병철,김대환,이창희,김휘동,이채언 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.5

        Objective : For the purpose of preparing the fundamental data and preventing the health impairment due yo heavy metals in hair cleaner. Methods and Material : The author determined the concentration of heavy metals(Fb, fn, Cr, Ni and Cu) in hair cleaner with flameless atomic absorption spectrophotometer. Results : The results were as follows : 1. The mean concentration of heavy metals in total hair cleaner were 0.046㎍/g for Pt, 0.O67㎍/g for Mn, 0.069㎍/g for Cr, 0.046㎍/g for Ni, and 0.022㎍/g for Cu, respectively. 2. There was not statistically significant difference to mean concentrations of each heavy metal in hair cleaner by producing nation. 3. The highest mean concentration of each heavy metal in hair cleaner by type of use were 0.140㎍/g for Mn in sensitive hair cleaner(p<0.05), 0.053㎍/g for Cu in others products(p<0.01). 4. The mean concentration of heavy metals in hair cleaner by type of hair cleaner were high at 0.O54㎍/g for Pb in shampoo products(p<0.O5), 0.120㎍/g for Cr and 0.06㎍/g for Cu in combination products(p<0.01). 5. The mean concentration of heavy metals in hair cleaner by acidity were high at 0.056㎍/g for Pb, 0.124㎍/g for Cr, and 0.032㎍/g for Cu in alkali products (p<0.05). 6. Correlation coefficient of heavy metal concentration in hair cleaner were 0.175 for Pb and Cr, 0.165 for Pb and Mn, 0.824 for Cr, and Mn, 0.189 for Cr, and Ni, 0.406 for Cr, and Cu, 0.197 for Mn and Ni, and 0.375 for Mn and Cu(p<0.05). 7. Exposure amount of heavy metals per when we used lOg of hair cleaner (onetime using amount) were 0.46㎍ for Pb, 0.67㎍ for Mn, 0.69㎍ for Cr, 0.46㎍ for Ni, and 0.22㎍ for Cu, respectively. Conclusion : As above results, there was very low level concentration of heavy metal in hair cleaner but we are using the hair cleaner everyday, therefore we can exposed to heavy metals as cronic exposure so the author suggest to prepare the program of preventing the health impairment due to heavy metals.

      • 尋常性좌창(Acne Vulgaris)에 對한 Vibramycin의 臨床的效果

        洪起煥,安順姬,朴定圭,李水月 中央醫學社 1973 中央醫學 Vol.25 No.4

        尋常性?瘡이 顔面에 甚한 女高生 40名을 double-blind試驗에 依하여 Vibramycin(Vibramyin 100mg을 1日 1回 經口的으로 投與)을 投與하여 다음의 結果를 얻었다. 1) Vibramycin 4週間 投與하였을 때 治癒率 은 80.0%이고 placebo를 投與時는 29.3%를 나타내었다. 그리고 治療效果는 投藥 3週에 顯著이 나타나기 始作하였다. 2) 投藥中止後 3週에는 治癒率이 Vibramycin 投藥群에서 減少를 보였으며 2名은 再發되었다. 3) 投藥 4週동안 治療效果가 不充分한 患者에게 3週間 더 延長하였을 때는 더욱 顯著한 效果를 볼 수 있었다. Forty high school girls with acne vulgaris were included in a double-blind trial to assess the tLapeu tic effect of Vibramycin (100 mg Vibramycin capsule, orally, once daily). The results, assessed clinically are as follows; 1. When Vibramycin was administered for 4 weeks, the cure rate showed 80. 0% and in the case of placebo, 29.3%, and the effectiveness was significantly appeared at 3 weeks of treatment. 2. In follow-up study, at 3 weeks after cessation of Vibramycin treatment, the cure rate decreased in Vibramycin group, and especially, in two girls, rashes like as inflammatory papules and pustules was reappeared. 3. When Vibramycin was administered another 3 weeks in addition, to those whom the effectiveness was insufficient in spite of 4 week-treatment, it had showed significantly beneficial effect.

      • KCI등재

        축 수직단면 형상정의에 의한 대형 스크류의 가공시 공구간섭검사

        이원규,안중환,박규열 韓國工作機械學會 2000 한국생산제조학회지 Vol.9 No.3

        In machining screws which are important members in mono pumps or progressive cavity pumps, CNC turning center with 3 axes is usually used. This soil of screw machining requires large amount of CL data points and rotational tools are used in machining. When working out the CL data points, consideration of possible tool interference is important in order to avoid undercut. This paper describes the checking methods of tool interference that could occur in the screw machining on the CNC turning center. First of all a specific shape of a screw cross-section that could commonly be applied to all screws was chosen, and then possible tool interference associated with that shape was identified. Checking method was mathematically developed and verified. This checking method will be utilized in the CAM system developed by the authors for screw machining on the 3-axis CNC turning center.

      • KCI등재후보

        경련 발작에 대한 초·중·고교 응급처치교육 모듈 평가

        조준필,박남수,안정환 韓國學校保健學會 2009 韓國學校保健學會誌 Vol.22 No.1

        Purpose : The purpose of this study was to evaluate the effectiveness of first aid education module on convulsion and seizure for students in elementary, middle and high school. Methods : This study has implemented to 2 types of test groups and control group in each 3rd and 5th grade of elemenary school, 2nd grade of middle school and high school within target school. The data were collected through a self-reported questionnaire to before, after and one month after education from July, 11 to September 4, 2007. Results : The test group who received first aid education possessed greater knowledge about convulsion and seizure relative to the control group not received education. The overall students has satisfied and been understood well with this module. The educators agreed to the practical aspects of this module in school setting. Conclusion : The above results implicated the importance of a continuous and systematic first aid education program among students. For effective first aid education, there needs a development of targeted educational materials for each grade student and training programs for educators.

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