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      • S-21 Usefulness of Anchoring Technique for Prevention of Stent Migration in Esophagorespiratory Fistula

        ( Hyoung Joon Shim ),( Tae Yoon Lee ),( Young Koog Cheon ),( Chan Sup Shim ) 대한내과학회 2016 대한내과학회 추계학술대회 Vol.2016 No.1

        Background:?Coated SEMS (self-expandable metal stent) placement is the preferred therapy for malignant esophagorespiratory fistula (ERF) at present. Migration is more frequent in coated stent than uncoated stent. Migration can occur immediately after stent placement and is likely secondary to malpositioning, inadequate anchoring, soft nonconstricting tumors, or complete coating of the stent. The overall risk of migration is approximately 10%. To prevent migration, we have used the anchoring technique, called Shim’s technique in Korea, connecting stent to ear with silk thread.?Patients and Methods:?Seven patients with malignant ERF were included. ERF conditions liable to migration of stent were selected. The selection criteria were ERFs without stricture (3 cases), with short length of stenosis (2 cases), and with soft consistency around fistula (2 cases). The anchoring method was designed to hang stent to ear lobe. Auricle was used for a post to suspend stent by a thread until the fixation of stent on the esophageal wall. The coated stent was specially designed for antimigration which has small circumferential uncoated portion on proximal flange part of stent for fixation. After 5 days of stenting, we removed the anchoring silk from the stent. Sealing of fistula were assessed with clinical improvement and esophagogram.?Results:?There were no migrations after stent placement in all 7 cases. Symptoms of aspiration were improved in all 7 cases.?Conclusions:?The anchoring technique was useful for the prevention of stent migration in esophagorespiratory (ERF) cases, especially in the conditions that stent are apt to be migrated.

      • 바람에 의한 정사각주형 건물주위의 유동해석

        서상호,노형운,심준완,이광열 崇實大學校 生産技術硏究所 1994 論文集 Vol.24 No.-

        It is necessary to understand fully the effects of wind forces on buildings, specially high-rise buildings in a large city. Air flows around a cubic-shaped model are investigated experimentally in the wind tunnel and simulated numerically. Pressure distributions and the corresponding pressure coefficients are determined by the experimental results. The pressure distribution results are compared with the numerical analysis. The software of FLOW3D Release 3.2.1 is used for numerical analyses. The numerical results for pressure distribution are in fairly good agreement with those of experiments.

      • Real Life Data of Daclatasvir and Asunaprevir Combination Therapy for Korean Patients Infected with HCV G1b without NS5A Resistance: Retrospective Multicenter Study

        ( Hyoung Su Kim ),( Myoung Kuk Jang ),( Ki Tae Suk ),( Dong Joon Kim ),( Sang Hoon Park ),( Myung Seok Lee ),( Ji Won Park ),( Sung Eun Kim ),( Choong Kee Park ),( Jae Jun Shim ),( Sang Bong Ahn ),( D 대한간학회 2017 춘·추계 학술대회 (KASL) Vol.2017 No.1

        Aims: Daclatasvir (DCV) and asunaprevir (ASV) combination therapy has shown a high viral efficacy for chronic genotype 1 (G1) hepatitis C virus (HCV) infected patients. However, the real life efficacy and safety of the therapy for Korean patients with HCV G1 infection are unknown. This study was aimed to investigate the efficacy and safety of DCV and ASV combination therapy in Korean patients infected with HCV G1b without NS5A resistance. Methods: A total of 145 chronic HCV genotype 1b patients treated with DCV+ASV were enrolled and analyzed in a multicenter retrospective cohort. Results: The study population was female dominant (54.5%) with 52.2 years. Thirty seven percent (56/145) had cirrhosis and 40% (58/145) had previous history of HCV treatment at baseline. HCV RNA and ALT levels were 5.82±0.70 log10IU/mL and 64.6±85.1 IU/L, respectively. Of the total 145 Patients, 142 Patients (98%) were completed DCV and ASV combination therapy for 24 weeks. Only 3 patients had early discontinuation therapy (viral breakthrough; 2 and financial problem; 1). Rapid viral response rates at week 4 were observed in 125 among 132 patients (94.7%). The viral response rates at the end of treatment were 96.6% (140/145). Sustained viral response (SVR) rates at post treatment week 12 were 95.1% (136/143). There were no serious adverse events. The most common adverse events were headache and fatigue. Aminotransferase increases of greater than five times the ULN were observed in 5 patients. Conclusions: DCV and ASU combination therapy provided high SVR rates and was well tolerated in Korean patients with HCV G1b infection without NS5A resistance.

      • 그린카 스마트시티 구현을 위한 기초연구

        ( Joon Ho Ko ),( Tae Hyoung Gim ),( Se Hee Lee ),( Jin Seop Shim ) 서울시정개발연구원 2011 연구보고서 Vol.2011 No.1

        As the Seoul Metropolitan Government (SMG) is trying to encourage the use of electric vehicles as the Green Car Smart City declaration, it is necessary to develop an electric vehicle (EV) delivery plan considering Seoul`s transportation characteristics. This study aims to identify strategies and issues associated with the introduction of various types of EVs based on transportation data. In addition, this study proposes organizational frameworks for fulfilling the plan and estimates benefits such as emissions reduction and energy savings and costs for the plan implementation. Although the SMG set up a plan for delivering more than 20,000 private EVs among the total 40,000 EVs, the encouragement of the private EV use was found to be significantly difficult because of high EV prices and short of charging infrastructure. Meanwhile, taxies and buses were found to be less difficult and more economical because of their long travel distances, fixed route operations (for buses) and easier installment of charging stations in depot. For EV taxies, pilot projects may be implemented cooperating with large taxi companies with more than 100 fleet. The location of rapid charging stations may be detemiined depending on the amount of taxi traffic volumes. In the case of EV buses, buses operated on rather short routes, for example less than 20km can be the target. In addition, some portions of motorcycles and rental cars may be converted to EVs. For private EVs, 3,500 EVs may be on the road by mid 2013, which include 2,200 new cars annually, 720 company fleet vehicles, 150 rental cars and 390 car sharing fleet. Concerning rapid charging facilities, 80 charging posts located at 40 different places may be provided in order to ease the EV drivers` anxiety. Candidate locations would be district offices, near the ramps of inner circular expressway, roadways crossing the city boundary and Hangang bridges. Besides these, 20 more fast charging posts may be installed in 10 depots of company taxies. For public standard chargers, several public facilities such as public parking lots, civic centers and libraries would be candidate locations. In the private sector, large buildings with a floor area of more than 30,000m2 would be the target for the installment of chargers. The pace of the charging facility provision should be coupled with the number of EV purchases. The proposed ratio of the numbers of EVs to public chargers are 5:1 until mid 2013, and after then the ratio may be adjusted to 8:1. These plans would be implemented by public-private partnership where the SMG may provide administrative and financial supports. As an active measure, the SMG may take the role to lead the plans, directly managing and controlling the EVs by setting up an EV center. The analysis on expected benefits and costs for the deployment of 40,000 EVs indicated that Seoul may see greater benefits of emissions reduction and fuel savings than the cost incurred by EV purchase subsidy and infrastructure construction. In more detail, the analyses suggested that B/C ratio for the four vehicle types (private car, bus, taxi, and motorcycle) would range between 0.90 and 1.01 depending on electricity prices if the benefits last five years. If it lasts seven years, B/C ratio would range between 1.26 and 1.41. Considering that the B/C ratio of private EV sector resulted in only 0.49~0.77, the public sector EVs such as taxies and buses would generate great benefits. Meanwhile, the low B/C ratio for the private EVs implies that government should lead the promotion of EV uses in the private sector for vitalizing related industries and spreading environment friendly transportation modes.

      • Analysis of relationship between grades for carcass yield and meat quality in Hanwoo

        Joon-Yong Shim,Byoung-Kwan Cho,Changyeun Mo,Jin-Hyoung Kim,Wang-Hee Lee 한국산업식품공학회 2018 학술대회 및 심포지엄 Vol.2018 No.04

        Both carcass yield and meat quality are important indices for beef grade, and consequently they are crucial factors for determining beef consumption and price. However, an optimal slaughter time for satisfying high carcass yield and meat quality has not been systemically evaluated, and identifying the time requires their relationship. Therefore, the objective of this study is 1) to examine the distribution of carcass yield by quality index, and 2) to investigate correlation between factors for judging grades of carcass yield and meat quality. We applied statistical analysis (ANOVA and correlation) for the data of Hanwoo (892 data points: bulls=311, cows=163, steers=418) slaughtered from 1995 to 2006. As a result of ANOVA, the mean difference of carcass yield in quality grade 3 was different with grade 1+, 1, and 2(p<0.05). In the correlation analysis, the meat quality grade showed a positive weak correlation with carcass yield (r=0.259, p<0.05), but was negatively correlated to carcass weight and back-fat thickness which were factors for carcass yield index calculation (-0.225 and -0.154, respectively, p<0.05). The results provide an initial idea for relating carcass yield and quality so that we can use it for determining the optimal time for slaughting.

      • KCI등재SCISCIE

        Novel Promoter Polymorphism in RUNX2 Is Associated with Serum Triglyceride Level.

        Shin, Hyoung Doo,Jeon, Jae-Pil,Park, Byung Lae,Bae, Joon Seol,Nam, Hye-Young,Shim, Sung-Mi,Park, Kyong Soo,Han, Bok-Ghee Korean Society for Molecular Biology 2008 Molecules and cells Vol.26 No.5

        <P>Much research evidence supports the hypothesis that chronic, low-grade inflammation related to innate immunity may play an important role in the pathophysiology of type 2 diabetes mellitus (T2DM). Runt-related transcription factor 2 (RUNX2; MIM# 600211) acts as a scaffold that controls the integration, organization, and assembly of nucleic acids. To examine whether the novel promoter variant in RUNX2 is associated with the risk of T2DM and related phenotypes, RUNX2-742G > T was genotyped in 378 T2DM patients and 382 normal controls recruited in the Korean T2DM Study. Statistical analysis revealed that RUNX2-742G > T was associated with serum triglyceride level (TG) in nondiabetic controls, although it was not associated with the risk of T2DM. Individuals who carry T/T, T/G, and G/G genotypes had the highest (2.061 +/- 0.20), intermediate (2.01 +/- 0.19), and the lowest (1.97 +/- 0.18) levels of log [TG (mmol/l)] (P = 0.007), respectively. Our data on this important variant of RUNX2 suggest that lipid metabolism might be affected by genetic polymorphisms in the promoter region.</P>

      • 농업빅데이터 관리 시스템의 효율적 관리·활용을 위한 대시보드 프로토타입 개발

        심준용 ( Joon-yong Shim ),이혜림 ( Hye-rim Lee ),고현석 ( Hyeon-seok Ko ),류수현 ( Su-hyun Ryu ),박수향 ( Su-hyang Park ),안정훈 ( Jeong-hoon An ),최근형 ( Geun-hyoung Choi ),최만호 ( Man-ho Choi ),박수진 ( Soo-jin Park ) 한국농업기계학회 2022 한국농업기계학회 학술발표논문집 Vol.27 No.2

        현재 농촌진흥청에서는 각 도농업기술원과 국내 시설원예 스마트팜 및 노지에서 생산되는 환경, 생육, 경영 등의 전주기 빅데이터를 수집하고 있다. 데이터셋 구축 목적은 생산성 향상, 수급안정 모델 등 다양한 농업 R&D 모델을 개발하기 위함이다. 이렇게 실시간으로 수집되는 대용량의 데이터를 효율적으로 관리하기 위해 농촌진흥청 내에서 농업빅데이터관리시스템(ABMS, Agricultural bigdata management system)을 운영하고 있다. 이 시스템을 통해 빅데이터를 안정적으로 저장·관리를 하고 있으며, 연구자들의 데이터 접근이 용이하도록 시스템 환경을 제공하고 있다. 농업빅데이터 관리 시스템 대시보드는 각 도에서 생산되는 데이터를 종합하고 실시간으로 데이터 현황을 모니터링할 수 있는 상황판이다. 대시보드에 포함되는 항목으로는 품목별 생육조사 주요 항목 및 방법, 도별 수집 농가 수, 컨설팅 횟수 등 데이터 입·출력 현황을 비교하면서 데이터 생산자 및 관리자에게 유용한 정보 확인이 가능하도록 구성되어 있다. 현재 ABMS에서는 도원별 수집현황, 데이터 누락 여부 등을 확인할 수 있는 현황판이 사용자 맞춤형으로 제공되지 않아 데이터 공유·활용 차원에서 개선점이 필요하다. 따라서 본 연구에서는 농업 빅데이터 관리 시스템 대시보드를 제작하여 전국 현장 데이터 수집·관리에 있어 체계적으로 현황을 파악하고 모니터링할 수 있는 시각화된 현황판을 구현하고자 한다. 대시보드 연계의 가장 주된 목적은 데이터 생산자와 관리자에게 유용한 정보를 제공함으로써 데이터의 신뢰성을 실시간으로 확인하고 시설, 노지 전주기 데이터를 체계적으로 관리하여 품질을 제고하기 위함이다. 향후 표준화된 데이터 수집·관리 방안을 기반으로 데이터 분야별 메타정보를 관리하는 고도화된 시스템으로 구축하고, 농업 빅데이터 특성에 맞게 사용자들의 접근성을 높이는 분석정보 및 환경을 제공할 계획이다.

      • 그린카 스마트시티 구현을 위한 기초연구

        고준호 ( Joon Ho Ko ),김태형 ( Tae Hyoung Gim ),이세희 ( Se Hee Lee ),심진섭 ( Jin Seop Shim ) 서울시정개발연구원 2011 연구보고서 Vol.2011 No.14

        As the Seoul Metropolitan Government (8MG) is trying to encourage the use of electric vehicles as the Green Car Smart City declaration, it is necessary to develop an electric vehicle (EV) delivery plan considering Seoul`s transportation characteristics. This study aims to identify strategies and issues associated with the introduction of various types of EVs based on transportation data In addition, this study proposes organizational frameworks for fulfilling the plan and estimates benefits such as emissions reduction and energy saving and costs for the plan implementation. Although the SMG set up a plan for delivering mire than 20,000 private EVs among the total 40,000 EVs, the encouragement of the private EV use was found to be significantly difficult because of high EV prices and short of charging infrastructure. Meanx4tile, taxies and buses were found to be less difficult and more economical because of their long travel distances5 fixed route operations (for buses) and easier installment of charging stations in depot. For EV taxies, pilot projects may be implemented cooperating with large taxi companies with mare than 100 fleet, The location of rapid charging stations may be determined depending on the amount of taxi traffic volumes. In the case of IN buses, buses operated on rather short routes5 for example less than 20km can be the target. In addition, some portions of niitorcycles and rental cars may be converted to EVs. For private EVs, 3,500 EVs may be on the road by mid 2013, ``which include 2,200 new cam annually, 720 company fleet vehicles, 150 rental cars and 390 car sharing fleet. Concerning rapid charging thciities, 80 charging posts located at 40 different places may be provided in order to ease the EV drivers`` anxiety. Candidate locations would be district offices, near the ramps of inner circular expressway, roadways crossing the city boundary and Hangang bridges. Besides these, 20 more fast charging posts may be installed in 10 depols of company taxies. For public standard chargers, several public facilities such as public parking lots, civic centers and libraries would be candidate locations. In the private sector, large buildings with a floor area of more than 30,000m2 would be the target for the installment of chargers. The pace of the charging facility provision should be coupled with the nunfrr of EV purchases. The proposed ratio of the nunters of EVs to public chargers are 5:1 until mid 2013, and alter then the ratio may be adjusted to 8:1. These plans would be implemented by public-private partnership where the SMG may provide administrative and financial supports. As an active measure; the SMG may take the role to lead the plans, directly managing and controlling the EVs by selling up an WV center. The analysis on expected benefits and costs for the dep1oynnt of 40,000 EVs indicated that Seoul may see greater benefits of emissions reduction and fuel savings than the cost incurred by EV purchase subsidy and infrastructure construction. In more detail, the analyses suggested that B/C ratio for the four vehicle types (private car, bus, taxi, and motorcycle) would range between 0.90 and 1.01 depending on electricity prices if the benefits last five years. If it lasts seven years, B/C ratio would range between 1.26 and 1.41. Considering that the B/C ratio of private WV sector resulted in only 0.49 0.77, the public sector EVs such as taxies and buses would generate great benefits. Meanwhile, the low B/C ratio for the private EVs implies that government should lead the promotion of EV uses in the private sector for vitalizing related industries and spreading environment friendly transportation modes.

      • KCI등재

        시장형 공기업의 원가효율성 분석

        안형태(Hyoung-Tae An),심동희(Dong-Hee Shim),김재준(Jae-Joon Kim) 한국관리회계학회 2020 관리회계연구 Vol.20 No.3

        [연구목적] 본 연구의 목적은 우리나라 공기업의 원가효율성을 자료포락분석을 통하여 측정하여 시장형 공기업과 준시장형 공기업의 원가효율성을 분석하고, 현행 공기업 경영평가지표와 DEA를 통한 원가효율성을 비교분석하는데 있다. 공기업에서 시행되고 있는 경영실적 평가방법은 경영관리범주와 주요사업범주로 구성된다. 이러한 경영실적 평가방법이 공기업의 소기의 경영성과를 가져왔다고 할 수도 있지만, 다른 한편으로는 경영평가지표 자체의 한계로 인해 경영평가 결과에 대한 신뢰성 및 수용성 문제가 종종 제기되고 있다. 본 연구에서는 현행의 경영평가 방법을 일부 보완할 수 있는 공기업 경영평가지표를 제안하고자 한다. [연구방법] 2018년도 기준 16개 시장형 공기업과 19개 준시장형 공기업을 대상으로 비모수적 방법으로 상대적 효율성을 측정하는 분석방법인 DEA 모형을 이용하여 원가효율성을 분석하였다. DEA 효율치 측정을 위한 투입요소로는 총자산, 인원수, 자기자본을, 산출변수로는 매출액을 선정하였다. [연구결과] CCR모형에서는 시장형과 준시장형 공기업 간에 원가효율성의 차이가 없었으며, BCC모형에서는 시장형 공기업의 원가효율성이 준시장형 공기업의 원가효율성 보다 유의하게 큰 것으로 나타났다. 또한 공기업 경영실적 평가시스템의 신뢰성에 대한 근거를 제시하고자 공기업 경영실적 평가 결과와 DEA로 측정한 원가효율성을 비교한 결과, 기존 경영실적 평가 결과와 DEA 원가효율성 간의 일관성은 다소 부족한 것으로 나타났다. [연구의 시사점] 본 연구에서는 공기업에 대한 전반적인 경영효율성의 현실을 파악함으로써 원가효율성의 정책적 경영지원에 대한 가이드라인을 제공하고자 하였으며, 현행 경영평가지표와의 비교·분석을 통해 부가적인 공기업 경영평가지표를 제안하고자 하였다. [Purpose] The purpose of this study is to compare and analyze current management evaluation indexes with cost efficiency measured through DEA for each market-type public enterprise and quasi market-type public enterprise. Current management evaluation indexes is consist of two categories which are business management and main business. Although these management evaluations have resulted in the expected results, such as promoting efficiency in the operation of public enterprise, the limitations of the management evaluation itself often raised the issue of acceptability and reliability of the results of the management evaluation. This study aims to propose a public enterprise evaluation method that compensated the shortcomings that current evaluation method has. [Methodology] This study analyze cost efficiency measured through DEA for each 16 market-type public enterprises and 19 quasi market-type public enterprises in 2018. Total assets, number of persons, and equity were selected as input elements for DEA analysis, and sales were selected as variables for calculation. [Findings] There was no difference in CCR model, while BCC model showed significant difference between cost efficiency of market-type and quasi market-type enterprises. In addition it was shown that there’s low consistency between existing management performance assessment and cost efficiency measured through DEA. [Implications] By grasping the reality of overall management efficiency for public enterprises this study provides guidelines for policy management support for management efficiency and at the same time proposing additional management evaluation index for public enterprises.

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