http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : ( Gbks Prasad ) (검색결과 4 건)
- 무료
- 기관 내 무료
- 유료
-
-
Evaluation of Cucurbita ficifolia Juice as a Hepatoprotec tive Drug in Human Type 2 Diabetes
( Dhananjay Yadav ),( Amita Jain ),( Meerambika Mishra ),( Arvind Tiwari ),( Gbks Prasad ) 대한간학회 2018 춘·추계 학술대회 (KASL) Vol.2018 No.1
Aims: The present study has been undertaken to analyze the hepatoprotective potential of Cucurbita ficifolia juice in type 2 diabetic subjects. Methods: A total 34 subjects were selected for the study out of which 14 subjects were with type 2 diabetes mellitus, 10 subjects were selected as a normal control group and 10 sub jects were selected as a normal treated group. The patients had type 2 diabetes for more than 2 years, their mean age was less than 45 years, and subjects were then asked to start the Cucur bita ficifolia juice therapy starting at day 0 and continuing up to 40 day both for diabetic and normal subjects. Liver enzymes such as. serum glutamic-oxaloacetic transaminase (SGOT), se rum glutamic-pyruvic transaminase (SGPT), and bilirubin were measured. Results: After 40 days of Cucurbita ficifolia juice therapy, there was a decrease of 9.45% and 27.85% (P<0.01) for SGPT and total serum bilirubin, while the SGOT levels increased by 2.02% in the case of diabetic treated subjects that was not found to be significant. Conclusions: The liver enzymes measured in our study amelio rated in type 2 diabetic patients. The results suggest that the Cucurbita ficifolia juice therapy could be used as a hepatopro tective drug in type 2 diabetes.
-
Effect of Herbal Medicines on Liver Function Markers in Type II Diabetic Subjects
( Senthil Kumar Subramani ),( Sunil Mahajan ),( Parthia Chauhan ),( Nita Singh ),( Gbks Prasad ) 대한간학회 2018 춘·추계 학술대회 (KASL) Vol.2018 No.1
Aims: Herbal medicines have been used in the treatment of liver diseases and other problem for a long time in folk system. However there are some reports in general state that, herbal medicine has hepatotoxicity. Hence in the present study we evaluate some anti-diabetic herbal medicines effect in liver function markers Methods: Total of 100 subjects those who have T2DM were randomly selected from the week end diabetic clinic of Centre for Translation Research, Jiwaji University. The subjects have divided in to four groups to evaluate for its antidiabetic activity and hepatotoxicity. Regimen I- Gymnemma sylvester, Regimen II- Triphala, Regimen III Triphala + Gymnemma sylvester and Regimen IV diabegon kwath (polyherbal formulation) for 3 - 4 months. Fasting and PP blood glucose and glycosylated hemo globin, liver marker (Bilirubin, SGOT, SGPT) and oxidative stress markers (SOD, Catalase, GSH, TBARS) were also monitored in the study subjects. Paired t-test was made the compare the sig nificance Results: Administration of herbal regiments regularly for 3 months resulted in significant reductions of blood glucose (P<0.001) and glycosylated hemoglobin levels (P<0.001) in all regiments. Also, liver function markers (Bilirubin levels reduced 12.5-15.6 % P<0.05, SGOT levels reduced 7.5 - 18.0 % P<0.05 and SGPT levels reduced 11.8-17.8% P<0.05 P<0.05) and the antioxidant markers were also improved significantly (P<0.05). Conclusions: Herbal medicines for the treatment of human type II diabetes mellitus show the significant improvement in glycemic control. The liver functions remained normal and in fact improved in many subjects. It may be the due to the an ti-oxidant property of the herbal formultions.Hence the studied herbal formulations not have hepatotoxicity in the subjects.
-
( Senthil Kumar Subramani ),( Rohit Sharma ),( Arjun Yadav ),( Shailendra Raghuwanshi ),( Gbks Prasad ) 대한간학회 2020 춘·추계 학술대회 (KASL) Vol.2020 No.1
Aims: Liver disease is one of the most common and occurs asymptomatically until disease affects a significant part of the organ. Probiotics are live microorganisms promoted with claims that they provide health benefits when consumed adequate amount, health benefits including antidiabetic, anti-inflammatory and antioxidant properties. This study aimed to determine the effects of probiotic supplementation on liver function and oxidative stress biomarkers in Type II Diabetes mellitus (T2DM) patients. Liver disease is one of the most common and occurs asymptomatically until disease affects a significant part of the organ. Probiotics are live microorganisms promoted with claims that they provide health benefits when consumed adequate amount, health benefits including antidiabetic, anti-inflammatory and antioxidant properties. This study aimed to determine the effects of probiotic supplementation on liver function and oxidative stress biomarkers in Type II Diabetes mellitus (T2DM) patients. Methods: In a randomized double-blind placebo-controlled clinical trial, 60 Subjects with aged 30-65 years were selected from CTR, Jiwaji University and assigned into two groups; Subjects in the probiotic group received a daily capsule containing Lactobacillus acidophilus, Bifidobacterium bifidium & Saccharomyces boulardii each 0.5 Bn/g and Lactobacillus plantarum, Bacillus clausii each 0.25 bn/g with 125mg FOS. BD for 12 weeks. (Placebo group only 125mg FOS in a capsule). In the baseline and at the end of the study, physical activity levels, and dietary intakes were assessed. Anthropometric parameters, blood glucouse, Liver function markers malondialdehyde (MDA), superoxide dismutase (SOD), reduced glutathione (GSH), and catalase (CAT) activities were measured. Statistical analysis was carried out using a paired t-test and student t- test. Results: There was no significant difference between the two groups for demographic characteristics, anthropometric parameters at the baseline of study. The mean fasting blood glucose levels were reduced by 16.3%.The probiotic supplementation resulted in a significant improvement in bilirubin by 22.3%, 15.9% ALP 17%,10.2% SGOT 27.2, 22.5%, SGPT 17.9, 17.1% GTT 13.9, 11.9% in subjects taken probiotic placebo capsules respectively. It also observed that the significant increase in GSH (P<0.01), SOD (P<0.01), CAT (P<0.01) and decrease in MDA level (P<0.01). Significant difference was observed between-group for these enzymes activities & other parameters at the end of the study. Conclusions: Overall, the results demonstrate that probiotics could improve liver function and oxidative stress factors among T2DM patients.
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
