Expansin으로 형질전환 된 담배의 생장 특성

신하정, 성현정, 백승준, 김보미, 엄유리, 조은정, 정찬문, 이이 충북대학교 연초연구소 2008 煙草硏究 Vol.21 No.-

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우리 나라 보건관리대행서비스 평가 연구

하은희,조수헌,김선민,주영수,한상환,하미나,권호장,홍윤철,김창엽 大韓産業醫學會 1998 대한직업환경의학회지 Vol.10 No.1

Group occupational health service programme started in 1990 is one of the measures to cope with limited human and financial resources in occupational health. The programme has expanded rapidly to include 52 institutions, private as well as public, all over the country. In spite of its potential impact on health of employees and practice of occupational health in small and medium sized industries, comprehensive evaluation in terms of quality has not been tried. This study has aims to develop the criteria to assess the quality of newly developed group occupational health service programme, and to investigate the quality of institutions, and finally to develop policies for the quality improvement. 1) Criteria development : By defining occupational health services, in particular for small and medium sized industries, as one of the primary health care, followings are included as core elements of qualitative occupational health programme; accessibility, continuity, comprehensiveness, technical quality, intersectoral collaboration, emphasis on preventive services, community participation, and adequacy. Again each element is divided into five major components of national health system infrastructure developed by the World Health Organization; development of health resources, organized arrangement of resources, delivery of health care, economic support, and management. In turn, each component is categorized into three aspects of quality assessment, structure, process and outcome. Expert panel selected several criteria for each category to evaluate the programme. Criteria were modified according to each group of interviewees, to produce two sets of questionnaire, one for chief operating officer and another for nurses in the institutions, and the chief operating officer and workers in the workplace. 2) Subject : Of all 52 institutions, 25 voluntarily participated in the survey. At individual institution, chief operating officer and practicing nurses were interviewed in depth. After intensive education for interviewees, every interviewees, every interview was performed with standardized guideline and questionnaire. The quality of the 'Group occupational health service programme' was found to be lower than expected. Especially in continuity, comprehensiveness, technical quality, community participation and adequacy, lower quality in structural aspect was commonly identified throughout all the institutions,. Quality in terms of accessibility and continuity highly varied among institutions., To improve quality of the programme, more comprehensive and systematic programme such as accreditation has to be introduced. In addition, human resources, governmental fund and information systems for individual workers are to be developed. As a long range plan, integration of occupational health services into the national health systems and pooling of financial resources and planned allocation should be considered.

빠른 매핑(fast mapping) 프로그램이 정신지체아동의 언어능력에 미치는 영향

유은미,권도하 대구대학교 특수교육재활과학연구소 2006 再活科學硏究 Vol.24 No.1

This study is done to find out if the program is effective on improvement of learning new nouns, verbs. and adjectives on metal retarded children with limited ability of words, as well as effective on development of semantic relation and on improvement lexical diversity that children take in. The participants for this study are three children with developmental years of 3 to 4 and IQ of 50 to 70. This study is examined by Ab Design which contains 3 main processes; 1) Pre-test Stage, 2) Treatment Stage, 3) Post-test Stage. The program is designed to examine the preparatory stage to select target words and treatment stage contains 3 main precesses such as word exposure stage, word comprehensive stage, word expressive stage. The results for the study are shown as below.; First, all participated children under the study have improved their ability to learn new vocabularies. Especially, ti has been more effective on comprehensive ability of vocabulary than expressive ability of vocabulary. Second, all participants have positive changes in semantic relation. Third, all participated children under the study have improved their TTR As on can see results above, the fast mapping program is certainly effective on improving linguistic competence of the mental retarded children. 본 연구는 빠른 매핑 프로그램을 이용한 중재가 낱말 능력에 제한을 보이는 정신지체아동의 명사와 동사, 그리고 형용사의 어휘력 증가에 영향을 미치는지, 또한 이렇게 습득된 명사와 동사, 그리고 형용사가 의미 관계의 출현빈도와 어휘다양도(Type-Token Ratio)의 증가에 영향을 미치는지에 대해 알아보고자 하였다. 언어 연령이 3~4세이고 지능지수가 50~75인 아동 3명이 이 연구에 참여하였다. 이 연구는 사전평가단계(pre-test stage), 치료 단계(treatment stage), 사후 평가 단계(post-test stage)를 가진 Ab design으로 설계되었으며, 프로그램의 구성은 목표 어휘 선정을 위한 준비 단계와 어휘 노출 단계(word exposure stage), 어휘 이해 단계, 어휘 산출 단계의 치료 단계로 이루어져 있다. 본 연구의 결과는 다음과 같다. 첫째, 대상 아동 모두 어휘력이 증가하였다. 특히, 산출 어휘력보다는 이해 어휘력에서 더욱 큰 효과를 나타내었다. 둘째, 대상 아동 모두 의미관계에서 긍정적인 변화를 나타내었다. 아동들은 모두 치료 전 많이 사용하던 의미관계의 단계가 전체 발화 수에서 차지하는 비율이 줄어드는 대신, 그 보다 높은 의미관계의 단계가 전체 발화 수에서 차지하는 비율이 증가하였다. 셋째, 대상 아동 모두 어휘다양도가 증가하였다. 이상의 결과를 살펴보았을 때, 빠른 매핑 프로그램이 정신지체아동의 언어능력에 영향을 미쳤다.

「부인필지」에 수록된 주식류와 침채류 조리법에 관한 문헌적 고찰

이미정,김기숙,신은하 중앙대학교 생활과학연구소 2000 생활과학논집 Vol.13 No.-

"Puinpilji" was written in 1915. We compared the cooking methods of the kinds of staple food and Chimche in "Puinpilji" with those in other cooking books. Patbap, without adding boiled redbean itself, was cooked with the boiled redbean water. The sweetness and color of Yakbap came from honey and the boiled jujube water. Tarakjuk was cooked with the same amount of milk and water. When rice was half cooked, milk was added. Patjuk was made by boiling together with a large amount of jujube and redbean. On kneading Saeal, ginger-juice was added. Tongchimi-kukmul and Jidan was used in Myongwolkwan-Naengmyon. The characteristics of Ouyuk-kimchi was that the boiled water with meat and dried fish was added to Kimchi. And also, Myongwol-Saengchiche made by adding meat of pheasant to Tongchimi-kukmul and Chonbok-chimche made by adding various materials to Junbok soaked in water were introduced in the text.

말단 비대증의 임상적 특성

박은미,안용환,김현정,김병수,임종주,김하영,박병현,조정구 圓光大學校 醫科學硏究所 2004 圓光醫科學 Vol.19 No.2

시간지연 시스템에 대한 출력궤한 H∞ 제어

정은태,김성미,권성하 國立 昌原大學校 産業技術硏究所 1997 産技硏論文集 Vol.11 No.-

This paper presents an H∞controller design method for linear time-invariant systems with delayed state and control. Using the second method of Lyapunov, the stability for delayed systems is discussed. For delayed systems, we derive a sufficient condition of the bounded real lemma(BRL)which is similar to BRL for nondelayed systems. And the sufficient conditions for the existence of an output feedback H∞controller of any order are given in terms of three linear matrix inequalities(LMIs). Futhermore, we briefly explain how to construct such controllers from the positive definite solutions of their LMIs and give a simple example to illustrate the validity of the proposed design procedure.

Suppression of lung inflammation by the methanol extract of <i>Spilanthes acmella</i> Murray is related to differential regulation of NF-κB and Nrf2

Kim, Kyun Ha,Kim, Eun Jung,Kwun, Min Jung,Lee, Ji Yeon,Bach, Tran The,Eum, Sang Mi,Choi, Jun Yong,Cho, Sayeon,Kim, Sang-Jun,Jeong, Seung-Il,Joo, Myungsoo Elsevier 2018 Journal of Ethnopharmacology Vol.217 No.-

<P><B>Abstract</B></P> <P><B>Ethnopharmacological relevance</B></P> <P>Although <I>Spilanthes acmella</I> has been used to relieve inflammation, fever, pain, or infection in traditional Asian medicine, experimental evidence supporting these functions is scarce. Here, we examined an anti-inflammatory function and a possible underlying mechanism of <I>S. acmella</I> Murray (SAM).</P> <P><B>Materials and method</B></P> <P>The methanol extract of SAM was fingerprinted by HPLC. C57BL/6 mice were administered with a single intratracheal (i.t.) LPS and 2 h later with a single i.t. SAM. The effect of SAM on lung inflammation was assessed by histology, semi-quantitative RT-PCR, and MPO assay of lung tissue. The effects of SAM on a pro-inflammatory factor NF-κB and an anti-inflammatory factor Nrf2 were analyzed by immunoblotting of nuclear proteins and by semi-quantitative RT-PCR analysis of mRNA of the genes governed by these transcription factors. V5-Nrf2 was precipitated by an anti-V5 antibody and the ubiquitinated V5-Nrf2 was revealed by immunoblotting of HA-tagged ubiquitin.</P> <P><B>Results</B></P> <P>The i.t. SAM robustly diminished a neutrophilic lung inflammation induced by i.t. LPS treatment of mice. In RAW 264.7 cells, SAM suppressed the nuclear localization of NF-κB and the expression of NF-κB-dependent cytokine genes. SAM increased the level of Nrf2 in the nucleus and the expression of Nrf2-dependent genes while suppressing ubiquitination of Nrf2.</P> <P><B>Conclusion</B></P> <P>Our results suggest that SAM can suppress a neutrophilic inflammation in mouse lungs, which is associated with suppressed NF-κB and activated Nrf2. Our results provide experimental evidence supporting the anti-inflammatory function of <I>S. acmella</I>.</P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

도서지방민의 신체의식에 대한 조사연구

유명의,박우미,위은하 東新大學校 1999 論文集 Vol.11 No.-

This study focused on the comparison of satisfaction with and perception about their bodies by Wando women and an examination the relationship between satisfaction and perceived of their body type. The respondents included 87 Wando woman volunteers, aged 15 to 65, who have lived over 15 years in Wando region. The questionnaire was composed of three sections; body measument, a body cathexis, perceived body shape-self. For each body site, All of Wando women were: dissatisfied with their thighs and hips of lower body. The older women perceived their body type as neutral even though they have a large body type. So even though the younger women were smaller In body build than the older women, the younger women were more negative about their body type than the older women.

새로운 이핵 다금속 화합물

노동윤,이하진,서은미 서울여자대학교 자연과학연구소 1999 자연과학연구논문집 Vol.11 No.-

백금과 철이 포함되는 새로운 이핵 다금속 화합물인 (dppf) Pt (deydt), (dppf) Pt (ebmdt)와 (dppf) Pt (bmddt)를 합성하여 IR, UV, 고분해능 FAB 질량분석, x-선 구조분석, 순환 전압-전류법으로 분석하였다. (dppf)Pt(ebmdt)와 (dppf)Pt(bmddt)의 순환 전압-전류법 분석결과 리간드의 가역적인 산화가 먼저 일어난 후 약 1.4 V에서 가역적인 〔(dppf)Pt〕^2+의 산화가 관측되었다. 그러나 (dppf)Pt(deydt) 화합물의 경우 1. 25 V에서 가역적인 〔(dppf)Pt〕^2+의 산화가 일어난 후 1. 45 V에서 리간드의 분해로 예상되는 비가역성 산화 피이크가 관찰되었다. (dppf)Pt(deydt) 화합물의 x-선 구조분석을 185 K의 저온에서 수행하였음에도 말단의 두 -COOCH_2CH_3 기 가운데 하나가 심하게 disorder되어 있는 것으로 분석되었다. New platinum(Ⅱ) complexes, (dppf)Pt(deydt), (dppf)Pt(ebmdt) and (dppf)Pt(bmddt)(dppf: 1,1'-bis(diphenylphosphino) ferrocene; deydt: diethylester ylidenedithiolate; ebindt: 1,2-ethylenebis(methylester)-1,2-dithiolate; bmddt:5,6-bis(methylester)-1,4-dithiin-2,3-dithiolate) were synthesized and analyzed by FT-IR, UV-vis, high-resolution FAB Mass, SEM and cyclic voltammetry. Single crystal of (dppf)Pt(deydt)·(CH_3OH) was grown in dichloromethane/methanol, the molecular structure of which was clucidated by x~ray structure analysis. Crystal data at 185±2 K are a=10.6290(4), b=23.3624(10), c=17.5956(7) Å, β=105.8930(10)°, P2(1)/c, V=4202.3(3) Å^3, Z=5, R=0.0819 and wR=0.1988. According to the cyclic voltammetry, ligand oxidation occurred at lower potential than that of [(dppf)Pt]^2 for (dppf)Pt(ebmdt) and (dppf)Pt(bmddt), however, [(dppf)Pt]^2 oxidation was followed by the ligand decomposition for (dppf)Pt(deydt) complex.

동서양의 식용꽃에 대한 고찰 : 조리방법을 중심으로

김영순,이정희,오순덕,정은미,최지영,유은순,장정미,정진선,하상민 高麗大學校 倂設 保健大學 保健科學硏究所 2001 保健科學論集 Vol.27 No.2

Edible flower means a flower that is good to eat is subject to either cooking or appetizing. In general, people eat edible flower as raw so that the loss of vitamin and inorganic are minimal. Edible flower is usually utilized as salad material or aromatic, decoration for jelly or cake and solid stuff in soup. Thus, decorating food by edible flower improves flavor, fragrance and appetite. Edible flower serves various purposes both east and west. In Korea, Edible flower is mainly subject to soup, cooked potherbs, frying, tea stuff, brewing and etc, whereas in Japan, its various usage covers cooked potherbs, pickle, sliced raw fish, frying, salad, jelly and decoration. On the other hand, Edible flower is used as numerous salad and tea stuff, condiment, roasting, meat, sweets and desserts in Western Hemisphere.