Acupuncture Treatment about Medial Meniscus Posterior Horn Rupture : A Case Report

Lee, Hey-Jin,Lee, Nam-Heon,Son, Chang-Gue,Cho, Jung-Hyo Research Institute of Korean Medicine 2020 혜화의학회지 Vol.29 No.2

Objectives : In this case, the knee joint inconvenience with deteriorating pain has been relieved by acupuncture treatment for a patient was 51-year-old male with a left medial meniscal posterior horn rupture in 2012. Methods : Twenty-four times of acupuncture treatments were performed for Twelve weeks from July 2016 to improve the disease. SP8(Jigi; 地機), BL63(Geummun; 金門), KI3(Taegye; 太谿), LI4(Hapgok; 合谷) were chosen for treatment by principles of Traditional Korean Medicine. Results : Numeric Rating Scales, which means subjective pain, decreased from 6 points to 3 points out of 10 points in total. Pressure Pain Threshold, which means sensitivity to pressure applied to the affected area, increased from 21N to 47N on the lateral-inferior side and from 19N to 50N on the lateral side. K-WOMAC, which indicates discomfort of knee-related activity, was 56 points out of 96 points in total before treatment and 4 points after treatment, 13 points after two years, and 15 points after four years. However, MRI tests conducted before and after treatment did not identify any significant changes. As a result, we confirmed that a total of 24 acupuncture treatments had resulted in the relief objective and subjective pain and functional recovery, especially in the case of the knee function, maintained until after four years later. There was no significant substrate recovery in meniscal rupture.

Acupuncture Treatment about Medial Meniscus Posterior Horn Rupture : A Case Report

Hey-Jin Lee,Nam-Heon Lee,Chang-Gue Son 大田大學校 附屬 韓方病院 2020 惠和醫學 Vol.29 No.2

Obectives: In this case, the knee joint inconvenience with deteriorating pain has been relieved by acupuncture treatment for a patient was 51-year-old male with a left medial meniscal posterior horn rupture in 2012. Methods : Twenty-four times of acupuncture treatments were performed for Twelve weeks from July 2016 to improve the disease. SP8(Jigi; 地機), BL63(Geummun; 金門), KI3(Taegye; 太谿), LI4(Hapgok; 合谷) were chosen for treatment by principles of Traditional Korean Medicine. Results : Numeric Rating Scales, which means subjective pain, decreased from 6 points to 3 points out of 10 points in total. Pressure Pain Threshold, which means sensitivity to pressure applied to the affected area, increased from 21N to 47N on the lateral-inferior side and from 19N to 50N on the lateral side. K-WOMAC, which indicates discomfort of knee-related activity, was 56 points out of 96 points in total before treatment and 4 points after treatment, 13 points after two years, and 15 points after four years. However, MRI tests conducted before and after treatment did not identify any significant changes.As a result, we confirmed that a total of 24 acupuncture treatments had resulted in the relief objective and subjective pain and functional recovery, especially in the case of the knee function, maintained until after four years later. There was no significant substrate recovery in meniscal repture.

암의 종류 및 증상에 따른 삶의 질 평가 척도에 관한 연구 현황 분석

이남헌,조정효,손창규,유화승,이연월,윤담희,이종훈,방선휘,조종관,Lee, Nam-Heon,Cho, Jung-Hyo,Son, Chang-Gue,Yoo, Hwa-Seung,Lee, Yeon-Weol,Yoon, Dam-Hee,Lee, Jong-Hoon,Bang, Sun-Hwi,Cho, Chong-Kwan 대한한방내과학회 2006 大韓韓方內科學會誌 Vol.27 No.3

Objectives : The objective of this study is to analyze what quality of life(QOL) scales are frequently used in cancer patients and lay a cornerstone to develop new QOL scales adequate for oriental medical anti-cancer treatment in the future. Methods : We searched 151 articles concerned with 'QOL and scale and cancer' from PubMed and classified them according to periods. nations. cancer types and symptoms. Results: 138 articles(91%) were published after 1996. 65 articles(43%) were published in USA. For breast. lung, prostate. esophageal cancer and melanoma. European Organization for Research and Treatment of Cancer-quiality of life questionaire(EORTC-QLQ) was used most frequently to evaluate quality of life. Functional Assessment of Cancer Treatment(FACT) for bladder cancer. Hospital Anxiety and Depression Scale(HADS) for colorectal cancer and of Washington Quality of Life questionnaire(UW-QOL) for Head & Neck cancer were used repeatedly. And for the patients with the symptoms such as bone marrow depression. depression. pain. dyspnea. nausea & vomiting and voice change. the investigators used EORTC-QLQ mainly to evaluate QOL. FACT-An(anemia) for anemia. FACT-BMT(bone marrow transplant) for bone marrow depression were applicated generally. Conclusions It is anticipated that further investigations will be performed to develop adequate QOL scales for oriental medical anti-cancer therapy.

Silicone rubber 멤브레인을 이용한 압저항형 저차압센서의 개발

서창택,공성수,심준환,고광락,서현미,김영진,설철규,신장규,이종현 경북대학교 센서기술연구소 1998 센서技術學術大會論文集 Vol.9 No.1

A 4-beam piezoresistive differential pressure sensor using a silicone rubber membrane has been fabricated on the selectively diffused (100)-oriented n/n^(+)/n silicon substrates by an unique silicon micromachining technique using porous silicon etching. The width, length, and thickness of the beam is 120 μn, 600 μm, and 6 μm, respectively, and the thickness of the silicone rubber membrane was 36 gm. By the use of four-beam structure, the mechanical strength of the differential pressure sensor can be highly improved due to smaller shear stress. And the lower sensitivity of the sensor can be simply solved by combining two output signals of half-bridge. The effectiveness of the sensor is confirmed through an experiment and FEM simulation in which the differential pressure sensor is characterized.

고로슬래그를 굵은골재로 사용한 콘크리트강도에 관한 연구

김영인,고창옥,이채규,양승현 조선대학교 국토개발연구소 1994 국토개발연구 Vol.14 No.2

Blast furnace, by-product of iron industry has widely used as reclamation materials for pavement or harbour construction. The studies which make blast furnace slag use as aggregates for concrete have being actived owing to natural aggregates insufficiency. In order to use air cooled blast furnace slag as a coarse aggregate for concrete which was fixed to 440kg, 400kg, 360kg, 320kg, 280kg, 240kg of cement content were performed. This study is aimed to ascertain the feasibility of utilizing the concreate with crushed slag aggregates and to find specific properties such as slump air content, compresive strength, tensile strength, bending strength. The results of this study are summarised as follows; 1. On the base of 320kg of unit cement weight the strength according to each dry day are similar in the condition of 45% of w/c whereas in the condition of 50% of w/c the strength of 7-days are similar, but the strength of 28-days are different. 2. In the relation of δ25 - c/w, the strength of slag concrete is greater than that of crushed storn concrete in condition of epual c/w except 400kg/㎥. 3. Slag of concrete as aggregate is destoryed with mortar. 4. The relation of δ28 and tensile strength is very good(γ = 0.8), the equation of regression analysis is δt= 0.63+0.00598 × 28. 5. The reation of bend strength and w/c is liner(γ = 0.72) the equation of regression analysis is δb=80-0.69w/c. 6. It must be care to abtain equal workability to natual aggregate concrete because the change of water absorption is greate. The water content of slag concrete is more than that of crushed storn concrete to obtain the same workability. It must be careful to use blast furnace slag as a coarse aggregate for concrete. And after investgating the quality of demended concrete carefully, real mixing work must be done.

후두부에 발생한 유피낭종의 특징

최환준,탁민성,최창용,강상규,이영만,Choi, Hwan-Jun,Tark, Min-Seong,Choi, Chang-Yong,Kang, Sang-Gue,Lee, Young-Man 대한성형외과학회 2010 Archives of Plastic Surgery Vol.37 No.4

Purpose: Congenital dermoid cysts develop during the fusion of the embryo when the ectodermal tissue gets trapped in the line of fusion. Dermoid cysts of the head are rare lesions comprised of epidermal and mesodermal elements. Furthermore, dermoid cysts in the occipital area are extremely rare. Only a few cases of dermoid cysts in the posterior scalp have been reported. Especially, A bilateral, synchronous presentation in this location has not been reported previously in the literature. Methods: All 5 cases had a gradually enlarging mass of the posterior aspect of the scalp. The cysts were mobile, noncompressible, and non-tender, without evidence of an associated sinus tract, skin dimpling, discoloration, or communication with adjacent structures. The CT scan displayed a hypodense cystic lesions about -87 to +24 HU (Housefield units, average +3.2 HU) with hypodense capsule and no postcontrast enhancement. All tumors were found just under the skin, and were well encapsulated, so they were completely removed the mass with adjacent periosteum. Results: On gross findings, all tumors were oval-or round-shaped, and when the cystic tumor was cut open it presented a greasy and caseous substance. Histologically, all specimens contain desquamated squamous epithelium and keratin in the lumen and are encapsulated and lined by keratinized stratified squamous epithelium. And, all cases of posterior mass are the presence of adnexal structures. Conclusion: Appropriate diagnosis requires not only an index of suspicion for this rare tumor a very careful history and search for skin changes. Especially, CT can reveal the exact location of the cyst, its relationship with the adjacent structures. We think that occipital dermoids divide into superficial and deep type. In our cases, because they did not have intra-cranial involvement or fistula formation, they are superficial type. This report describes the clinical and operative aspects of the superficial dermoid cysts and provides a review of the literatures.

Changes of Serum VEGF and b-FGF in 26 Patients with Breast Cancer after Treatment with Hang-Am-Dan (HAD), an Antiangiogenic Botanical Prescription

Yoo Hwa Seung,Lee Nam Heon,Cho Jung Hyo,Lee Yeon Weol,Son Chang Gue,Kang Wee Chang,Cho Chong Kwan The Society of Korean Medicine 2005 대한한의학회지 Vol.26 No.4

Objectives: Recently, angiogenesis has gained an increasing interest as a prognostic factor in breast cancer. In this study we aimed to assess the anti angiogenic effects of HAD, a botanical anticancer remedy which has been prescribed in Daejeon University Oriental Hospital in Korea, on patients with breast carcinoma by measuring the serum vascular endothelial growth factor (VEGF), basic fibroblast growth factor (b-FGF) and platelets levels. Methods: The study included 26 consecutive breast cancer patients (mean age$\pm$standard deviation: 47.5$\pm$8.7 years) with stage II to IV disease who were treated with HAD (mean duration $\pm$ standard deviation: 264.5$\pm$121.6 days). In addition to routine laboratory and staging procedures, serum VEGF, b-FGF levels and platelet counts were determined as antiangiogenic markers. The antiangiogenic effects of HAD were evaluated by analyzing the differences between the values of the antiangiogenic markers before and after the treatment with HAD. Results: Serum b-FGF concentrations were significantly reduced after the treatment with HAD (P=0.042). Serum VEGF concentrations were found to have a somewhat decreasing change, though the change was not statistically significant (P=0.229). Platelet counts had little changes (P=O.80). Conclusions: It is supposed that HAD has effects on decreasing the serum b-FGF levels related with the clinical outcome of breast cancer patients.

Herbal Transformation by Fermentation

Chang-Gue Son,Sam-Keun Lee,In-Kyu Choi,Eun-Su Jang,Kee-Jung Bang 사단법인약침학회 2020 Journal of Acupuncture & Meridian Studies Vol.13 No.5

We herein show a dramatic change of herbal properties of the composition as well as function via fermentation of Cynanchi atrati Radix (family Asclepiadaceae). Cynanchi atrati Radix showed a high cytotoxicity against B16-F10 melanoma cell line, but the function of Cynanchi atrati Radix was completely changed into anti-melanin activity at very low concentration after Lactobacillus -fermentation. In addition, the compounds were drastically changed as shown in HPLC-based profile. Furthermore, this transformation has been achieved by only Lactobacillus -fermentation. This study proposes an strategy which we need to consider in the herb-derived material researches including pharmacopuncture.

Combination Therapy of Gefitinib and Korean Herbal Medicines Could be a Beneficial Option for Patients with Non-Small-Cell Lung Cancer

Lee, Kangwook,Ryu, Juyoung,Son, Chang-Gue,Cho, Jung-Hyo,Yoo, Hwa-Seung,Lee, Jonghoon,Kim, Yoon-sik,Lee, Namhun KOREAN PHARMACOPUNCTURE INSTITUTE 2016 Journal of pharmacopuncture Vol.19 No.3

Lung cancer has a high mortality rate and is often diagnosed at the metastatic stage. Gefitinib is a targeted molecular therapeutic drug used to treat patients with non-small-cell lung cancer (NSCLC). Korean herbal medicines may also have therapeutic efficacy against lung cancer, reduce the side effects associated with chemotherapy, and improve patient quality of life (QOL). This case report describes the effects of a Korean herbal medicine regimen combined with gefitinib in a patient with NSCLC and bone metastasis. The Korean herbal medicine regimen included woohwanggeosa-dan, hwanggibujeong-dan and geonchilgyebok-jeong. The computed tomography (CT) findings showed that following combination treatment, the size of the tumor was markedly decreased without serious adverse events. Moreover, the Eastern Cooperative Oncology Group (ECOG) performance status was improved and cancer-related pain was decreased. These results suggest that a combination of Korean herbal medicines and gefitinib may be an effective therapeutic option for patients with advanced NSCLC and bone metastasis. Further studies are needed to examine the mechanism and the clinical efficacy of Korean herbal medicines against NSCLC.

CGplus, a standardized herbal composition ameliorates non-alcoholic steatohepatitis in a tunicamycin-induced mouse model

Lee, Myong-Min,Kim, Hyeong-Geug,Lee, Sung-Bae,Lee, Jin-Seok,Kim, Won-Yong,Choi, Seung-Hoon,Lee, Sam-Keun,Byun, Chang-Kyu,Hyun, Pung-Mi,Son, Chang-Gue Elsevier 2018 Phytomedicine Vol.41 No.-

<P>Conclusion: Our data present experimental evidence for the potential of CGplus as an herbal therapeutic against NAFLD and NASH. Its underlying mechanisms may involve the modulations of pro- and anti-inflammatory cytokines, but further study is required especially for the actions of CGplus on lipid metabolisms.</P>