Effects of Dietary Habits on General and Abdominal Obesity in Community-dwelling Patients with Schizophrenia

Mina Kim(Mina Kim),Soo Jin Yang(Soo Jin Yang),Hyang Hee Kim(Hyang Hee Kim),Anna Jo(Anna Jo),Min Jhon(Min Jhon),Ju-Yeon Lee(Ju-Yeon Lee),Seung-Hyung Ryu(Seung-Hyung Ryu),Jae-Min Kim(Jae-Min Kim),Young- 대한정신약물학회 2023 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.21 No.1

Objective: To investigate the effects of dietary habits on general and abdominal obesity in community-dwelling patients with schizophrenia spectrum disorder according to sex. Methods: A total of 270 patients with schizophrenia spectrum disorder registered at mental health welfare centers and rehabilitation facilities were recruited. General obesity was defined as a body mass index ≥ 30 kg/㎡, and abdominal obesity was defined as a waist circumstance ≥ 90 cm in men and ≥ 85 cm in women. Dietary habits were evaluated using dietary guidelines published by the Korean Ministry of Health and Welfare. Demographic and clinical characteristics along with dietary habits and information related to obesity were collected. Factors related to obesity were evaluated separately by sex. Results: Dietary habits differed according to sex, in that scores for healthy eating habits were lower in men than in women. In men, the prevalences of general and abdominal obesity were 17.0% and 37.3%, respectively. In women, the prevalences of general and abdominal obesity were 23.1% and 38.5%, respectively. Regression analysis showed that the scores of regular eating habits were negatively associated with general and abdominal obesity in men, and the scores of healthy eating habits were negatively associated with general and abdominal obesity in women. Conclusion: Among patients with schizophrenia, regular eating habits might reduce the risk of obesity in men, and healthy eating habits might reduce the risk of obesity in women. Nutrition education should be provided to community-dwelling patients with schizophrenia to prevent obesity in this population.

Generalized Tonic-Clonic Seizures after Self-Limited Epilepsy with Centrotemporal Spikes: A Case Series

Hye Jin Kim(Hye Jin Kim),Young Joon Ko(Young Joon Ko),Soo Yeon Kim(Soo Yeon Kim),Anna Cho(Anna Cho),Hunmin Kim(Hunmin Kim),Byung Chan Lim(Byung Chan Lim),Hee Hwang(Hee Hwang),Jong-Hee Chae(Jong-Hee Ch 대한소아신경학회 2022 대한소아신경학회지 Vol.30 No.4

Purpose: Patients with self-limited epilepsy with centrotemporal spikes (SLECTS) rarely experience generalized tonic-clonic seizures (GTCS) after remission, and post-remission GTCS has not been thoroughly described in earlier studies. Herein, we describe the clinical and electrographic features of GTCS after a substantial period of seizure freedom in patients with SLECTS. Methods: This study included six patients (three boys and three girls) diagnosed with SLECTS who later developed GTCS after or near remission. Medical records, including clinical data and serial electroencephalography (EEG) recordings, were retrospectively reviewed for all patients. Results: Patients’ age at SLECTS onset ranged from 5.2 to 10.2 years (mean, 8.4 years), while seizure cessation was achieved between 8 and 12.2 years. During SLECTS, typical centrotemporal spikes were observed in all patients, and generalized spike-and-wave discharges were observed in three patients. The age at the first episode of subsequent GTCS ranged from 14.4 to 17.3 years (mean, 15.8 years), constituting an average interval of 5.6 years after the last episode of seizures (range, 4.1 to 8.1 years). EEG at subsequent episodes of GTCS revealed generalized discharges in two patients, focal discharges in two other patients, and normal discharges in the remaining two patients. Two patients had multiple episodes of GTCS. Conclusion: Although rare, GTCS may occur near or after remission in patients with SLECTS, and clinicians should be aware of this. Subsequent GTCS may be a manifestation of idiopathic generalized epilepsy. However, large-scale studies are needed to determine the nature of such episodes of GTCS and their associated risk factors.

Effectiveness of Switching to Long-acting Injectable Aripiprazole in Patients with Recent-onset and Chronic Schizophrenia

Sung-Wan Kim(Sung-Wan Kim),Bong-Ju Lee(Bong-Ju Lee),Eun-Jin Cheon(Eun-Jin Cheon),Seung-Hee Won(Seung-Hee Won),Anna Jo(Anna Jo),Jae-Min Kim(Jae-Min Kim),Young-Chul Chung(Young-Chul Chung) 대한정신약물학회 2023 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.21 No.1

Objective: This study investigated the effectiveness of switching to once-monthly long-acting injectable (LAI) aripiprazole from other second-generation antipsychotics including LAI paliperidone palmitate in both recent-onset and chronic schizophrenia patients. Methods: This was a 24-week prospective, open-label, flexible dose-switching study in patients with schizophrenia. Scores on the Positive and Negative Syndrome Scale (PANSS), Personal and Social Performance (PSP) scale, Clinical Global Impression (CGI), Subjective Well-being Under Neuroleptics−Short Form (SWN-K), and a computerized emotional recognition test (ERT) were evaluated. Subjects were divided into two groups (recent onset and chronic) based on 5 years’ duration of the illness. Results: Among the 82 patients participating, 67 (81.7%) completed the 24-week study. The discontinuation rate after switching to LAI aripiprazole did not differ according to clinical characteristics including type of previous antipsychotics. Scores on the PANSS, PSP, SWN-K, CGI, and ERT were significantly improved after a switch to LAI aripiprazole without exacerbation of metabolic parameters and bodyweight. The improvements in the PANSS, PSP, and CGI scores were significantly greater in patients with recent-onset than in those with chronic schizophrenia; the improvement in metabolic parameters was significantly greater in the latter group. Conclusion: High rates of successful switching to LAI aripiprazole from other antipsychotics suggest its good tolerability and effectiveness. Improvements in psychopathology and social functioning were more evident in patients with recent- onset schizophrenia, and improvements in metabolic abnormalities were more prominent in patients with chronic schizophrenia.

Eccrine porocarcinoma: retrospective study and review of cases reported in Korea

( Anna Kim ),( Jiehyun Jeon ),( Aeree Kim ),( Soo Hong Seo ),( Il Hwan Kim ),( Hae Jun Song ),( Yoo Sang Baek ) 대한피부과학회 2019 대한피부과학회 학술발표대회집 Vol.71 No.2

Background: Eccrine porocarcinoma (EPC) is rare malignant cutaneous adnexal tumor. Since 1998, many EPC cases has been reported in Korea. All previous studies were limited to case report and none has comprehensively reviewed multiple cases. Objectives: To clinicopathologically review all EPC cases from our institutions as well as case reports in Korea. Methods: The patients were retrospectively selected from skin biopsy registry from our institutions. Available histopathological slides were re-examined by an experienced dermatopathologist. EPC cases reported in Korea before June 2019 were retrieved by searching PubMed, Google scholar, KoreaMed, and KoMCI. Results: Nine EPC cases from our institutions were included in the study. In addition, we found 27 reports of 28 EPC cases from Korea. In total of 37 EPC cases, there were 19 males (M:F ratio 1.06:1), and the mean age at diagnosis was 65.6 years. The most common site of primary tumor was head and neck (29.7%). Wide excision was the most common (78.4%) treatment method. Metastasis was confirmed in 21.1%. Conclusion: EPC is rarely reported cutaneous carcinoma in Korea. EPC usually affects old age patients with no sexual predilection. Due to possible metastasis, careful diagnosis and appropriate metastasis work up is warranted in EPC.

A case of large retroperi toneal leiomyoma with myomatous erythrocytosis syndrome

( Anna Kim ),( Hashin Kim ),( Jae Yeon Lee ),( Ki Hwan Kim ),( Kyu Ri Hwang ) 대한산부인과학회 2015 대한산부인과학회 학술대회 Vol.101 No.-

김정은 시기의 북한 고등교육정책 변화 방향 분석

김경미(Kim, Kyoungmi),김안나(Kim, Anna) 연세대학교 교육연구소 2020 미래교육학연구 Vol.33 No.3

본 연구의 목적은 사회주의 강성국가라는 국가적 과제에 대응하기 위한 김정은 시대 북한의 고등교육정책의 변화전략이 무엇인지 탐색하는 데 있다. 이에 본 연구는 북한 교육문화성이 발행한 교육신문 2012년~2019년 기사 중에서 ‘대학’, ‘고등교육’을 키워드로 수집한 1,255편의 기사를 분석하였다. 주요 결과는 다음과 같다. 첫째, 북한은 세계 일류급 고등교육을 강조하며 연구중심대학으로의 변화를 도모하며 과학기술연구 강조와 지식경제 시대에 대응하기 위한 지식을 생산하고자 하였다. 둘째, 대학을 유형별로 특성화하여 종합대학 일원화 및 박사 후 교육체계 마련, 직업기술대학체계를 확립하였다. 셋째, 대학교육의 질 향상을 위하여 원격교육 실행 및 교원의 교수 방법의 변화를 요구하였다. 넷째, 대학기능의 수월성 향상을 위하여 대학행정 시스템 및 대학입학 원격시험체계를 마련하고 인프라구축을 강화하고 있다. 이러한 연구결과를 토대로 본 연구는 북한과 같은 독특한 정치체제에서 교육정책의 변화가 북한사회의 변화에 어떤 영향을 미칠지 논의하였다. This study examines reform in higher education under Kim Jong-un that was motivated and defined by the strong influence of North Korea’s socialist ideology. To this end, 1,255 news articles containing the keywords “college” and “higher education” were analyzed. These were sourced from the Education Newspaper published by North Korean Education between 2012 and 2019.The study s conclusions are summarized below. First, North Korea seeks to develop a world-class higher education system modeled on research-centered institutions which emphasize science and technology for the new knowledge economy. Second, North Korea seeks to unify colleges, universities, post-doctoral studies, and vocational technology university system. Third, changes in the implementation of remote education and teaching methods were requested to improve the quality of university education. Fourth, infrastructure for improving university administration and remote testing for university admission have been emphasized and implemented to facilitate learning. This study discussed how changes in North Korean higher education policy reflect the unique characteristic of the political system and will shape future developments in North Korean society.

대소변 개인건강기록의 임상연계 활용 연구

김안나 ( Kim Anna ),김상현 ( Kim Sanghyun ),이승호 ( Lee Seungho ),김영은 ( Kim Young-eun ),장현철 ( Jang Hyunchul ) 대한한의학원전학회(구 대한원전의사학회) 2019 대한한의학원전학회지 Vol.32 No.1

Objectives : In this study, we analyze the medical significance of feces symptoms so that the daily records of the feces of individuals can be not only used as a measure of individual health monitoring in daily life, but also more actively connected to the medical treatment of the Korean Medicine (KM). Methods : Categories and clinically significant attributes for symptoms of Urination and defecation in the KM ontology DB are determined, and connected to KM related dialectical indicators by experts’ common criteria including Viscera and Bowels [臟腑], eight principles [八綱], Qi·Blood·fluid and humor·phlegm-retained fluid·static blood [氣血津液痰飮瘀血], six excesses [六淫]. Results : The analysis of the symptoms of feces in the Korea Medicine ontology shows that the symptoms of stool in categories of 'stool stiffness', 'blood swelling', 'discomfort' are highly ranked among the overall clinical symptom categories. In the case of urine symptoms, symptoms corresponding to 'urine color,' 'urine discomfort,' and 'urine volume' are the top rankers among other total clinical symptoms. In the case of stool, the relationship between the symptom of stool and the categories of spleen, stomach, and colon is increased as the weighted symptom is considered. The relationship between the symptom of urine and the categories of the small intestine and the bladder is increased in the same way. Conclusions : This study could help better utilize the personal generated health records of feces in clinical practice of Korean Medicine.

Eccrine Porocarcinoma: A Multicenter Retrospective Study with Review of the Literatures Reported in Korea

( Hee Joo Kim ),( Anna Kim ),( Kyung-chul Moon ),( Soo Hong Seo ),( Il-hwan Kim ),( Aeree Kim ),( Yoo Sang Baek ) 대한피부과학회 2020 Annals of Dermatology Vol.32 No.3

Background: Eccrine porocarcinoma (EPC) is a rare malignant cutaneous adnexal tumor. Other than several scattered case reports, no comprehensive review on EPC has been conducted in Korea. Objective: To clinicopathologically review all EPC cases from our institutions as well as those reported in Korea. Methods: Medical records and histopathological slides of EPC cases in the skin biopsy registries of our institutions were retrospectively reviewed. Additionally, EPC cases reported in Korea before June 2019 were retrieved by searching the PubMed, KoMCI, KoreaMed, and KMbase databases. Results: Nine EPC cases from our institutions were included in the study. In addition, 27 reports of 28 patients with EPC were reported in Korea. A total of 37 patients with EPC were identified, consisting of 19 males (male:female ratio, 1.06:1; mean age at diagnosis, 65.6 years). The most common site of primary tumor was the head and neck (29.7%). Wide excision was the most common (78.4%) treatment method. Initial metastasis work-up imaging studies were performed in 18 patients (48.6%), and metastasis was confirmed in eight patients (21.6%). Conclusion: EPC is a rare cutaneous carcinoma in Korea. EPC usually affects elderly patients, with no sexual predilection. Due to possible metastasis, careful diagnosis and appropriate metastasis workups are warranted in EPC. (Ann Dermatol 32(3) 223∼229, 2020)

Efficacy of loop electrosurgical excision procedure with cold coagulation for treating cervical intraepithelial neoplasia: A two center cohort study

( Hee Seung Kim ),( Jeong Eun Kwon ),( Jeong Ha Kim ),( Anna Kim ),( Na Ra Lee ),( Miseon Kim ),( Maria Lee ),( Dong Hoon Suh ),( Yong Beom Kim ) 대한산부인과학회 2017 Obstetrics & Gynecology Science Vol.60 No.2

Objective To evaluate the efficacy of loop electrosurgical excision procedure (LEEP) combined with cold coagulation for treating cervical intraepithelial neoplasia (CIN). Methods We reviewed clinic-pathologic data of 498 patients treated with LEEP alone (n=354), and LEEP combined with cold coagulation (n=144) between January 2000 and December 2011. After LEEP, we followed up all patients by using Papanicolaou smear and human papillomavirus (HPV) test, and evaluated abnormal cervical cytology-free interval and high-risk HPV infection-free interval. Moreover, we investigated independent factors affecting abnormal cervical cytology or high-risk HPV infection after LEEP. Results Abnormal cervical cytology-free interval was longer in patients treated with LEEP combined with cold coagulation than in those treated with LEEP alone (mean, 92.4 vs. 84.4 months; P=0.01), and patients treated with LEEP combined with cold coagulation also showed longer high-risk HPV infection-free interval than those treated with LEEP alone (mean, 87.6 vs. 59.1 months; P=0.01). Moreover, CIN 3 and cold coagulation were factors affecting abnormal cervical cytology after LEEP (adjusted hazard ratios, 1.90 and 0.61; 95% confidence intervals, 1.27 to 2.84 and 0.39 to 0.96), and CIN 3, positive deep cervical margin and cold coagulation were also factors affecting high-risk HPV infection after LEEP (adjusted hazard ratios, 2.07, 4.11, and 0.64; 95% confidence intervals, 1.38 to 3.08, 1.63 to 10.39, and 0.43 to 0.96). When we performed subgroup analyses for patients with CIN 2 or CIN 3, the result were similar. Conclusion LEEP combined with cold coagulation may be more effective for treating CIN than LEEP alone. Moreover, cold coagulation may decrease the risk of potential of recurrence after LEEP.

효율적인 한의 처방조제지원시스템 개발

김철(Chul Kim),김상균(Sangkyun Kim),장현철(Hyunchul Jang),김안나(Anna Kim),김익태(Iktae Kim),송미영(Miyoung Song) 한국한의학연구원 2010 한국한의학연구원논문집 Vol.16 No.3

The purpose of this study is to develop the order communication system for Traditional Korean Medicine(TKM) which can support prescribing decisions and provide the toxicological information. The relative vulnerability of the infrastructure of TKM has made us start the study. We carried out the benchmarking for TKM charting solution firstly, and then designed the intelligent search and supporting method for prescription decisions. We developed of the medical herbs database and the web-based order communication program which can be used in medical field actually. This system supplies a various functions to oriental medical doctors such as management for prescription history, search for herb’s effects, generating prescriptions, inventory management, alerting of toxicity and taboo, guideline for taking medicine, and so on. The design and implementation process has been described in this research. We expect that this system will play an important role in electronic medical record(EMR) or electronic health record(EHR) binding diagnosis and management functions.