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- 저자 : Zengkai Wang (검색결과 3 건)
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Prolonged antimicrobial activity of silver core-carbon shell nanoparticles
Zengkai Wang,Tianke Wang,An Hua,Song Ma,Zhidong Zhang,Lei Liu 한국화학공학회 2019 Korean Journal of Chemical Engineering Vol.36 No.11
Ag nanoparticles present good antimicrobial activity but with a potential toxicity to the cell, which limits the application. To address this issue, in this work, carbon-encapsulated sliver nanocapsules (Ag@C nanocapsules) were prepared by evaporating pure Ag ingot with the modified arc-discharge technique, and the Ag@C nanocapsules were acidified with nitric acid subsequently to facilitate the silver ion to release. Finally, Ag@C nanocapsules displayed a good and sustained antimicrobial activity against E. coli as a model of Gram-negative bacteria, due to the long-term release of sliver ions from Ag@C nanocapsules. The results obtained in this work indicate that the Ag@C nanocapsules may be a suitable nanomaterial for the bactericidal application.
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Effect of molecular weight of regenerated silk fibroin on silk-based spheres for drug delivery
Zengkai Wang,Xiangming Li,Yanhua Cui,Kai Cheng,Mingdong Dong,Lei Liu 한국화학공학회 2020 Korean Journal of Chemical Engineering Vol.37 No.10
Silk fibroin presents a good advantage as a drug carrier for drug delivery, due to the excellent biocompatibility, biodegradability and tunable drug loading and release properties. In this work, we constructed silk spheres by phase separation of the regenerated silk fibroin (RSF) solutions with different MW and polyvinyl alcohol; and it was revealed that MW of RSF can affect the structure, size, surface potential and drug loading and release efficiency of silk spheres. Silk spheres prepared from high MW of RSF were found to load more macromolecular drug with negative charge compared to middle and low MW of RSF. However, for the positive charge and low MW drug, the silk spheres prepared from low MW of RSF could present a high loading efficiency compared to other carriers. Finally, a positive drug with low MW, streptomycin was encapsulated in silk spheres prepared from low MW of RSF, and displayed a long bactericidal and bacteriostatic effect compared to bared streptomycin solution. The results obtained provide guidelines for the modification and options of drug transport vehicles for more efficient drug delivery and utilization through a simple, rapidly constructed, applicable and low-cost drug carrier.
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Yanhua Cui,Lili Yang,Yan Yan,Zengkai Wang,Jian Zheng,Binrong Li,Yonghai Feng,Chunxiang Li,Minjia Meng 한국화학공학회 2021 Korean Journal of Chemical Engineering Vol.38 No.2
The photocatalytic efficiency of conventional blending photocatalytic membranes suffers a significant reduction due to effective photocatalyst embedded in membrane matrix. Therefore, in this study, inspired by the bioadhesive technology of polydopamine (pDA), a novel Ti doped bismuth oxyiodide (BiOI)-polydopamine (pDA)-coated cellulose acetate (CA) (Ti/BiOI-pDA/CA) photocatalytic nanocomposite membranes were successfully developed for effective removal of tetracycline (TC). The Ti/BiOI-pDA/CA nanocomposite membranes displayed very high photocatalytic activity toward TC (about 98% after 120 min) under visible light irradiation and superior photodegradation kinetics (k=0.03214 min1). The removal rate of Ti/BiOI/-pDA/CA nanocomposite membranes under dynamic cyclic degradation system could be further improved, giving TC removal efficiency of 91% in 60min. Remarkably, the permeate flux, flux recovery ratio (FRR), reversible fouling (Rr), irreversible fouling (Rir) and the total fouling ratio (Rt) revealed the Ti/BiOI-pDA/CA nanocomposite membranes had excellent antifouling performance. In addition, the Ti/ BiOI-pDA/CA nanocomposite membranes exhibited excellent stability and reusability. Therefore, this work gives insight into the effective removal of TC wastewater and has a great potential for new generation of high-performance photocatalytic membranes for practical wastewater treatment in the future.
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