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Yutaka Okamura Korean Institute of Landscape Architecture 2004 Journal of the Korean institute of landscape archi Vol.2 No.-
The Yatomi - Aioiyama line is a city-planning road that was notified in 1957 and subsequently prepared by land readjustments. Currently, approximately 900m of road pass in the inside of the Aioiyama green area has not been constructed. The surveying briefing session for inhabitants was held in July 1992, the project was authorized by the Ministry of Land, Infrastructure and Transport in September 1993, and the project briefing session for inhabitants was held in September 1993. The site purchase has been completed. At the May 2000 briefing session, inhabitants of the area began voicing dissenting demanding the conservation of the natural environment of this green area. The inspector system serves as the third party, independent of both the administration and the inhabitants. Before finalizing the geometric line form of the road to be constructed, some surveys of animals and plants found along the walking trails carried out intensively in the northern area, which is approximately 50 ha, of the Aioiyama green area. The natural environment inspector submitted a plan for changing the geometric line form of the road decided upon by city planning, and it was approved by the city planning council. If the shelter structure or the retaining wall structure is adopted at the location where large slope faces are produced by excavation or landfill, and if the bridge structure is adopted at the place where stream-lines and walking trails intersect, it leads to a reduction of approximately $40\%$ in the areas for which change is planned. Furthermore, approximately $20\%$ of the area to be changed is restored by returning soil to the roof of the shelter.
Okamura, Takehiko,Ando, Ryosuke,Akita, Hidetoshi,Hashimoto, Yoshihiro,Iwase, Yutaka,Naiki, Taku,Kawai, Noriyasu,Tozawa, Keiichi,Kohri, Kenjiro Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.9
Objective: The guidelines on indications for prophylactic use of Bacille Calmette-Gu$\acute{e}$rin (BCG) against non-muscle-invasive bladder cancer (NMIBC) have changed over the years. In order to assess the impact on outcome, the present retrospective comparison of BCG efficacy by time period with Japanese patients was conducted. Patients and Methods: A total of 146 cases of NMIBC treated with BCG since February 1985 were retrospectively evaluated. All patients received 80 mg of BCG (Tokyo 172 strain) six to eight times a week for prophylactic use. Comparison was made among three historical groups (Group A: 1980's, 39 cases; Group B: 1990's, 61 cases; Group C: 2000's, 46 cases). Results: In total, recurrence was seen in 55 of the 146 cases (37.7%), and progression in 14 (9.6%), 1 patient dying of cancer. These overall results were similar to those outlined in previous reports. However, the outcomes of this time-period-based analysis indicated a tendency for a shorter time to recurrence in patients after 2000, although a log-rank test showed no significance (P=0.229). Seven of the cases featuring progression (i.e., half of all such cases) were among the 46 Group C patients (15.2%). Excluding these progressive cases, there was no significant difference among the remaining 132 patients in the three groups. Conclusion: This study results revealed a tendency for a lower non-recurrence rate after 2000 in our series. This could stem from a number of factors, including changes in BCG indication criteria and the evolution of histopathological diagnostic criteria.
In situ mass spectrometry of glucose decomposition under hydrothermal reactions
Pattasuda Duangkaew,Shuhei Inoue,Tsunehiro Aki,Yutaka Nakashimada,Yoshiko Okamura,Takahisa Tajima,Yukihiko Matsumura 한국화학공학회 2017 Korean Journal of Chemical Engineering Vol.34 No.5
We designed an in situ mass spectrometry (in situ MS) analysis method and developed to identify the products of glucose decomposition under hydrothermal condition for the first time. The in situ MS analysis was performed by coupling a tubular batch reactor with a quadrupole mass analyzer via custom-built connection fittings. The products of glucose decomposition were investigated by in situ MS, mass spectrometry of cold effluent, and high-performance liquid chromatography (HPLC) analysis of cold effluent and the results were compared. At 140 oC, in situ MS and mass spectrometry of cold effluent showed that the decomposition of glucose does not proceed; this was confirmed by comparison with the mass spectral database for glucose. At 180 oC or higher, a clear base fragmentation peak of 5-hydroxymethylfurfural (5-HMF) at position m/z 97 and that of furfural at m/z 96, formic acid (m/z=46) and levulinic acid (m/z=116) were observed by mass spectrometry. No levulinic acid or furfural was observed through conventional HPLC analysis under any condition; only glucose, formic acid, and 5-HMF could be detected. The effectiveness of in situ MS analysis is clear, compared to mass spectrometry analysis of cold effluent and HPLC analysis.
Suzuki Yugo,Ochiai Yorinari,Hosoi Atsuko,Okamura Takayuki,Hayasaka Junnosuke,Mitsunaga Yutaka,Tanaka Masami,Odagiri Hiroyuki,Nomura Kosuke,Yamashita Satoshi,Matsui Akira,Kikuchi Daisuke,Ohashi Kenichi 거트앤리버 소화기연관학회협의회 2024 Gut and Liver Vol.18 No.1
Background/Aims: Asymptomatic esophageal eosinophilia (aEE) is considered to be a potential precursor of eosinophilic esophagitis (EoE). However, there are few clinical parameters that can be used to evaluate the disease. Therefore, we aimed to clarify the factors involved in the symptoms of EoE by examining the clinicopathological differences between aEE and EoE. Methods: We reviewed 41 patients with esophageal eosinophilia who underwent endoscopic ultrasonography and high-resolution manometry. They were divided into the aEE group (n=16) and the EoE group (n=25) using the Frequency Scale for the Symptoms of Gastroesophageal Reflux Disease score. The patients’ clinicopathological findings were collected and examined. Results: The median Frequency Scale for the Symptoms of Gastroesophageal Reflux Disease score was 3.0 in the aEE group and 10.0 in the EoE group. There was no significant difference in patient characteristics, endoscopic findings and pathological findings. The cutoff value for wall thickening was 3.13 mm for the total esophageal wall thickness and 2.30 mm for the thickness from the surface to the muscular layer (total esophageal wall thickness: 84.0% sensitivity, 75.0% specificity; thickness from the surface to the muscular layer: 84.0% sensitivity, 68.7% specificity). The high-resolution manometry study was abnormal in seven patients (43.8%) in the aEE group and in 12 (48.0%) in the EoE group. The contractile front velocity was slower in the EoE group (p=0.026). Conclusions: The esophageal wall thickening in the lower portion of the esophagus is an important clinical factors related to the symptoms in patients with EoE.