Control of the Saturation Temperature in Magnetic Heating by Using Polyethylene-glycol-coated Rod-shaped Nickel-ferrite (NiFe2O4) Nanoparticles

Yousaf Iqbal,Hongsub Bae,이일수,Sungwook Hong 한국물리학회 2016 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.68 No.4

Polyethylene-glycol (PEG)-coated nickel-ferrite nanoparticles were prepared for magnetic hyperthermia applications by using the co-precipitation method. The PEG coating occurred during the synthesis of the nanoparticles. The coated nanoparticles were rod-shaped with an average length of 16 nm and an average diameter of 4.5 nm, as observed using transmission electron microscopy. The PEG coating on the surfaces of the nanoparticles was confirmed from the Fourier-transform infrared spectra. The nanoparticles exhibited superparamagnetic characteristics with negligible coercive force. Further, magnetic heating effects were observed in aqueous solutions of the coated nanoparticles. The saturation temperature could be controlled at 42 C by changing the concentration of the nanoparticles in the aqueous solution. Alternately, the saturation temperature could be controlled for a given concentration of nanoparticles by changing the intensity of the magnetic field. The Curie temperature of the nanoparticles was estimated to be 495 C. These results for the PEG-coated nickel-ferrite nanoparticles showed the possibility of utilizing them for controlled magnetic hyperthermia at 42 C.

Relaxivities of Hydrogen Protons in Aqueous Solutions of PEG-coated Rod-shaped Manganese-Nickel-Ferrite (Mn0.4Ni0.6Fe2O4) Nanoparticles

Yousaf Iqbal,배홍섭,이일수,홍성욱 한국물리학회 2014 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.65 No.10

Spinel-structured manganese (Mn)-nickel (Ni)-ferrite nanoparticles were synthesized using achemical co-precipitation method. Coating with PEG (polyethylene glycol) was simultaneouslyconducted along with the synthesis of Mn-Ni-ferrites. The X-ray diffraction (XRD) and theFourier-transform infrared (FTIR) analyses revealed a cubic spinel ferrite structure of the synthesizednanoparticles. Transmission electron microscopy (TEM) images showed that the synthesizednanoparticles were rod-shaped with a uniform size distribution and that the average length andwidth were 15.13 ± 1.32 nm and 3.78 ± 0.71 nm, respectively. The bonding status of PEG onthe nanoparticle surface was checked by using FTIR. The relaxivities of the hydrogen protons inthe aqueous solutions of the coated particles were determined by using nuclear magnetic resonance(NMR) spectrometry. The T1 and the T2 relaxivities were 0.34 ± 0.11 mM−1s−1 and 29.91 ± 0.98mM−1s−1, respectively. This indicates that the synthesized PEG-coated Mn-Ni-ferrite nanoparticlesare suitable for use as T2 contrast agents.

Intensive Analysis of Core—Shell Silica-Coated Iron-Oxide Nanoparticles for Magnetic Hyperthermia

Iqbal, Yousaf,Bae, Hongsub,Rhee, Ilsu,Hong, Sungwook American Scientific Publishers 2016 Journal of Nanoscience and Nanotechnology Vol.16 No.11

<P>We report the synthesis and characterization of silica-coated iron-oxide nanoparticles with a core-shell structure, which can be used for magnetic hyperthermia. The nanoparticles were synthesized by the reverse micelle method. The silica coating was performed simultaneously with the synthesis of the nanoparticles. The nanoparticles were characterized using various analytical tools. X-ray diffraction measurements confirmed their cubic spinel structure. Transmission electron microscopy (TEM) revealed monodisperse nanoparticles of nearly spherical core-shell structures with an average diameter of 17 nm. The bonding of the silica on the surface of the iron-oxide nanoparticles was confirmed by Fourier transform infrared spectrometry (FTIR). The silica-coated iron-oxide nanoparticles exhibited superparamagnetic properties with a saturation magnetization of 48.8 emu/g measured with a vibrating sample magnetometer (VSM). The applicability of the nanoparticles to magnetic hyperthermia was tested by measuring the temperature increase in an aqueous solution of nanoparticles in a 260 kHz alternating magnetic field. An optimum nanoparticle concentration of approximately 2.0 mg/ml achieved a saturation temperature of 42 degrees C, the target value for magnetic hyperthermia. The specific absorption ratio (SAR) for this sample was 87 W per gram of iron. The dependence of the SAR on the nanoparticle concentration and magnetic field strength was also measured. These results demonstrated the applicability of silica-coated iron-oxide nanoparticles to magnetic hyperthermia.</P>

Use of abdominal compression device in colonoscopy: a systematic review and meta-analysis

Yousaf Zafar,Ahmed Mustafa Rashid,Syed Sarmad Javaid,Ahmed Kamal Siddiqi,Adnan Zafar,Arsalan Zafar Iqbal,Jagpal Singh Klair,Rajesh Krishnamoorthi 대한소화기내시경학회 2023 Clinical Endoscopy Vol.56 No.4

Background/Aims: Colonoscopy for screening is associated with unpleasant experiences for patients, and abdominal compression devices have been developed to minimize these problems. However, there is a paucity of data supporting the therapeutic benefits of this strategy. This study examined the effects of using an abdominal compression device during colonoscopy on the cecal intubation time (CIT), abdominal compression, patient comfort, and postural changes. Methods: We searched PubMed and Scopus (from inception to November 2021) for randomized controlled trials that assessed the effects of an abdominal compression device during colonoscopy on CIT, abdominal compression, patient comfort, and postural change. A random-effects meta-analysis was performed. Weighted mean differences (WMDs) and Mantel-Haenszel odds ratios (ORs) were calculated. Results: Our pooled analysis of seven randomized controlled trials revealed that abdominal compression devices significantly reduced CIT (WMD, –0.76 [–1.49 to –0.03] minutes; p=0.04), abdominal compression (OR, 0.52; 95% confidence interval [CI], 0.28–0.94; p=0.03), and postural changes (OR, 0.46; 95% CI, 0.27–0.78; p=0.004) during colonoscopy. However, our results did not show a significant change in patient comfort (WMD, –0.48; 95% CI, –1.05 to 0.08; p=0.09) when using an abdominal compression device. Conclusions: Our findings demonstrate that employing an abdominal compression device may reduce CIT, abdominal compression, and postural change but have no impact on patient comfort.

Relaxivities of Hydrogen Protons in Aqueous Solutions of Gold-coated Manganese Ferrite Nanoparticles

Tanveer Ahmad,Yousaf Iqbal,배홍섭,이일수,홍성욱,장용민,이재준 한국물리학회 2013 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.62 No.11

Manganese ferrite nanoparticles were synthesized using the reverse micelle method and were coated with gold. TEM (transmission electron microscope) pictures showed that the shapes of the synthesized nanoparticles were almost spherical with an average diameter of 12 nm and a standard error of 4 nm. The bonding status of gold on the nanoparticle surfaces was checked using a Fourier transform infrared spectrometer (FTIR). The T1 and the T2 relaxation times of the hydrogen protons in aqueous solutions of the coated manganese-ferrite nanoparticles were determined using magnetic resonance imaging (MRI). The 1/T1 and the 1/T2 versus concentration curves for the nanoparticles showed a linear dependence. The T1 and the T2 relaxivities were found to be r1 =6.01 ± 0.12 and r2 = 83.3 ± 0.55 mM−1s−1. The ratio of r2/r1 was 13.9; this is larger than the ratios of r2/r1 for commercial T2 MRI contrast agents, indicating that the nanoparticles studied herein can serve as a T2 contrast agent with high efficacy.

Effect of partially replacing soybean meal with sunflower meal with supplementation of multienzymes on growth performance, carcass characteristics, meat quality, ileal digestibility, digestive enzyme activity and caecal microbiota in broilers

Yaqoob Muhammad Umar,Yousaf Muhammad,Imran Safdar,Hassan Safdar,Iqbal Waqar,Zahid Muhammad Umer,Ahmad Naveed,Wang Minqi 아세아·태평양축산학회 2022 Animal Bioscience Vol.35 No.10

Objective: An experiment was conducted to evaluate the effects of partially replacing soybean meal (SBM) with sunflower meal (SFM) with added exogenous multienzymes (MEs) on various biological parameters in broilers. Methods: One week-old, 400 broiler chicks were randomly divided into four treatments (control, 3SFM, 6SFM, and 9SFM) with 5 replicates/treatment (20 chicks/replicate). Control diet was without SFM and MEs, while diets of 3SFM, 6SFM, and 9SFM treatments were prepared by replacing SBM with SFM at levels of 3%, 6%, and 9%, respectively, and were supplemented with MEs (100 mg/kg). Feeding trial was divided into grower (8 to 21 day) and finisher phases (22 to 35 day). External marker method was used to measure the nutrient digestibility. At the end of trial, twenty birds (one birds per replicate) with similar body weight were slaughtered for samples collection. Results: No significant effect of dietary treatments was found on all parameters of growth performance and carcass characteristics, except relative weight of bursa. Weight (25.0 g) and length (15.80 cm) of duodenum were significantly (p<0.05) higher in 3SFM than control. Lowest (p<0.05) villus height/crypt depth ratio was found in 3SFM and 9SFM than control. Most of meat quality parameters remained unaffected, however, highest pH of breast meat (6.16) and thigh meat (6.44) were observed in 9SFM and 3SFM, respectively. Lowest (p<0.05) cook loss of thigh meat was found in 6SFM (31.76%). Ileal digestibility of crude protein was significantly (p<0.05) higher in 3SFM (72.35%) than control (69.46%). In addition, amylase (16.87 U/mg) and protease (85.18 U/mg) activities were significantly (p<0.05) higher in 3SFM than control. However, cecal microbial count remained unaffected. Conclusion: Partial replacement (up to 9%) of SBM with SFM, with added MEs can help to improve the nutrient digestibility, intestinal morphology, and digestive enzyme activities without affecting cecal microbial count and growth performance in broilers. Objective: An experiment was conducted to evaluate the effects of partially replacing soybean meal (SBM) with sunflower meal (SFM) with added exogenous multienzymes (MEs) on various biological parameters in broilers.Methods: One week-old, 400 broiler chicks were randomly divided into four treatments (control, 3SFM, 6SFM, and 9SFM) with 5 replicates/treatment (20 chicks/replicate). Control diet was without SFM and MEs, while diets of 3SFM, 6SFM, and 9SFM treatments were prepared by replacing SBM with SFM at levels of 3%, 6%, and 9%, respectively, and were supplemented with MEs (100 mg/kg). Feeding trial was divided into grower (8 to 21 day) and finisher phases (22 to 35 day). External marker method was used to measure the nutrient digestibility. At the end of trial, twenty birds (one birds per replicate) with similar body weight were slaughtered for samples collection.Results: No significant effect of dietary treatments was found on all parameters of growth performance and carcass characteristics, except relative weight of bursa. Weight (25.0 g) and length (15.80 cm) of duodenum were significantly (p<0.05) higher in 3SFM than control. Lowest (p<0.05) villus height/crypt depth ratio was found in 3SFM and 9SFM than control. Most of meat quality parameters remained unaffected, however, highest pH of breast meat (6.16) and thigh meat (6.44) were observed in 9SFM and 3SFM, respectively. Lowest (p<0.05) cook loss of thigh meat was found in 6SFM (31.76%). Ileal digestibility of crude protein was significantly (p<0.05) higher in 3SFM (72.35%) than control (69.46%). In addition, amylase (16.87 U/mg) and protease (85.18 U/mg) activities were significantly (p<0.05) higher in 3SFM than control. However, cecal microbial count remained unaffected.Conclusion: Partial replacement (up to 9%) of SBM with SFM, with added MEs can help to improve the nutrient digestibility, intestinal morphology, and digestive enzyme activities without affecting cecal microbial count and growth performance in broilers.

Effect of multi-enzymes supplementation on growth performance, meat quality, ileal digestibility, digestive enzyme activity and caecal microbiota in broilers fed low-metabolizable energy diet

Yaqoob Muhammad Umar,Yousaf Muhammad,Iftikhar Mubashir,Hassan Safdar,Wang Geng,Imran Safdar,Zahid Muhammad Umer,Iqbal Waqar,Wang Minqi 아세아·태평양축산학회 2022 Animal Bioscience Vol.35 No.7

Objective: This study was conducted to evaluate the effect of using low energy diet with multi-enzymes supplementation on different biological parameters in broilers. Methods: Three hundred Arbor Acres broiler chicks were randomly divided into three groups (Cont, standard metabolizable energy(ME); L-ME, ME reduced by 50 kcal/kg without enzyme; and L-ME-MES, L-ME diet was supplemented with multi-enzymes) with five replicates per group (20 chicks per replicate) at the start of second week. Grower and finisher diets were formulated according to breed specific guide and offered with free access in respective phase (two weeks for grower [8 to 21 d]; two weeks for finisher [22 to 35 d]). External marker method was used to measure the nutrient digestibility. After feeding trial, fifteen birds (one bird per replicate) were selected randomly and slaughtered for samples collection. Results: The results exhibited no effect (p>0.05) of dietary treatments on all parameters of growth performance, carcass traits, relative weight of internal organs except bursa and overall parameters of thigh meat quality. Relative weight of bursa was significantly (p<0.05) higher in L-ME than control. Multi-enzymes supplementation in low-ME diet significantly (p<0.05) improved the breast meat pH 24 h, digestibility of crude protein, duodenum weight and length, jejunal morphology, counts of Lactobacillus spp. and Bifidobacterium spp., lipase and protease activities than control. Jejunum length was increased in both L-ME and L-ME-MES treatments than that of the control (p<0.05). Breast meat cooking loss and color lightness was lower in L-ME (p<0.05) than control. Conclusion: It can therefore be concluded that broilers could be reared on low energy diet with supplementation of multi-enzymes without compromising the growth performance. In addition, it is beneficial for other biological parameters of broilers. Objective: This study was conducted to evaluate the effect of using low energy diet with multi-enzymes supplementation on different biological parameters in broilers.Methods: Three hundred Arbor Acres broiler chicks were randomly divided into three groups (Cont, standard metabolizable energy(ME); L-ME, ME reduced by 50 kcal/kg without enzyme; and L-ME-MES, L-ME diet was supplemented with multi-enzymes) with five replicates per group (20 chicks per replicate) at the start of second week. Grower and finisher diets were formulated according to breed specific guide and offered with free access in respective phase (two weeks for grower [8 to 21 d]; two weeks for finisher [22 to 35 d]). External marker method was used to measure the nutrient digestibility. After feeding trial, fifteen birds (one bird per replicate) were selected randomly and slaughtered for samples collection.Results: The results exhibited no effect (p>0.05) of dietary treatments on all parameters of growth performance, carcass traits, relative weight of internal organs except bursa and overall parameters of thigh meat quality. Relative weight of bursa was significantly (p<0.05) higher in L-ME than control. Multi-enzymes supplementation in low-ME diet significantly (p<0.05) improved the breast meat pH 24 h, digestibility of crude protein, duodenum weight and length, jejunal morphology, counts of <i>Lactobacillus</i> spp. and <i>Bifidobacterium</i> spp., lipase and protease activities than control. Jejunum length was increased in both L-ME and L-ME-MES treatments than that of the control (p<0.05). Breast meat cooking loss and color lightness was lower in L-ME (p<0.05) than control.Conclusion: It can therefore be concluded that broilers could be reared on low energy diet with supplementation of multi-enzymes without compromising the growth performance. In addition, it is beneficial for other biological parameters of broilers.

RESEARCH : Open Access ; Occurrence and identification of Emeria species in broiler rearing under traditional system

( Asim Shamim ),( Murtaz Ul Hassan ),( Arfan Yousaf ),( Muhammad Farooq Iqbal ),( Muhammad Arif Zafar ),( Rao Muhammad Siddique ),( Muhammad Abubakar ) 한국동물자원과학회(구 한국축산학회) 2015 한국축산학회지 Vol.57 No.41

The present study was intended to determine the prevalence and identification of species involved causing coccidiosis in broilers rearing under traditional farming system in Mirpur, Azad Kashmir, Pakistan. For the current study, a convenient sampling technique was carried out. A total of 7814 broilers (aged 1 to 6 weeks) were submitted to the Disease Diagnostic Laboratory of Livestock and Animal husbandry Department Mirpur, Azad Kashmir. Results: From the total screened, 750 were found positive for coccidiosis representing an overall prevalence of 9.59 %. Age-wise highest prevalence (10.88 %) recorded in the middle age birds (0 to 3 week old) were found more susceptible to infection than those aged above 3 weeks. Higher prevalence (12.49 %) of coccidiosis in broilers was observed in spring as compared with 6.60 % in summer season. In this study two main coccidiosis causing species, Emeria tenella and Emeria maxima were identified on the basis of their morphological feature and habitat (caeca and intestine), However, E. tenella was dominant compared to E. maxima. Conclusion: The study provides an insight to the occurrence of Emeria species which must be taken into consideration when rearing the broilers.

Occurrence and identification of Emeria species in broiler rearing under traditional system

Shamim, Asim,Hassan, Murtaz ul,Yousaf, Arfan,Iqbal, Muhammad Farooq,Zafar, Muhammad Arif,Siddique, Rao Muhammad,Abubakar, Muhammad Korean Society of Animal Sciences and Technology 2015 한국축산학회지 Vol.57 No.12

Background: The present study was intended to determine the prevalence and identification of species involved causing coccidiosis in broilers rearing under traditional farming system in Mirpur, Azad Kashmir, Pakistan. For the current study, a convenient sampling technique was carried out. A total of 7814 broilers (aged 1 to 6 weeks) were submitted to the Disease Diagnostic Laboratory of Livestock and Animal husbandry Department Mirpur, Azad Kashmir. Results: From the total screened, 750 were found positive for coccidiosis representing an overall prevalence of 9.59 %. Age-wise highest prevalence (10.88 %) recorded in the middle age birds (0 to 3 week old) were found more susceptible to infection than those aged above 3 weeks. Higher prevalence (12.49 %) of coccidiosis in broilers was observed in spring as compared with 6.60 % in summer season. In this study two main coccidiosis causing species, Emeria tenella and Emeria maxima were identified on the basis of their morphological feature and habitat (caeca and intestine), However, E. tenella was dominant compared to E. maxima. Conclusion: The study provides an insight to the occurrence of Emeria species which must be taken into consideration when rearing the broilers.

Chapatti sensory and textural quality in relation to whole meal flour and dough characteristics

Salman Khurshid,Saqib Arif,Hafiza Mehwish Iqbal,Qurrat Ul Ain Akbar,Shahid Yousaf 한국식품과학회 2020 Food Science and Biotechnology Vol.29 No.2

Current study was designed to evaluate sensory and textural quality characteristics of chapatti, a commonly consumed flat bread in South-Asia in relation to flour quality parameters. Whole meals of cultivars and commercial wheat samples were analysed for physicochemical, pasting, dough and baking properties. Flours contained medium protein contents (12.4–13.7%) and possessed medium to high gluten strength (51–88). Pasting and dough properties were also suitable for chapatti making. Chapatti sensory attributes were strongly related to gluten content (r = -0.915) and strength (r = 0.851). Moderate relationships were also observed with protein (r = -0.665), falling number (r = -0.750), water absorption (r = -0.623) and maximum viscosity (r = -0.745) of whole meal flours. Tearing force for chapatti was largely related to gluten content (r = -0.893) and dough development time (r = 0.847) but also showed reasonable relationships with gluten index (r = 0.643), ash (r = 0.640), falling number (r = -0.681), maximum (r = -0.743) and breakdown (r = -0.650) viscosities. The information would be useful for household and commercial semi-mechanical chapattimaking process.