단일 기관에서 경험한 소아청소년기 Kikuchi-Fujimoto병의 임상적 고찰

강희원,김한울,이소영,유경하,김혜순,유은선,최희정,김경효 이화여자대학교 의과학연구소 2018 EMJ (Ewha medical journal) Vol.41 No.4

Objectives: Kikuchi-Fujimoto disease (KFD) is characterized by lymphadenopathy and fever, and is usually self-limited. This study analyzed the clinical characteristics of pediatric patients with KFD. Methods: This retrospective, observational, single-center study was conducted in South Korea from March 2008 to October 2015. KFD was diagnosed based on clinical, radiological or histological findings and excluded when there were any other causes of lymphadenopathy. Medical records were reviewed for clinical and laboratory manifestations. Results: A total of 35 cases were included. The mean patient age was 12.1±2.9 years (range, 5 to 17 years); the male-to-female ratio was 1:0.8. The main clinical manifestations were cervical lymphadenopathy and fever in 34 cases (97%). The mean duration of fever was 12.2±8.3 days (range, 2 to 37 days). We noted enlargement of lymph nodes in the cervical, mesenteric (n=5, 14%), axillary (n=2, 6%), and inguinal (n=1, 3%) regions. Hepatosplenomegaly, loss of appetite, and rash were observed. On laboratory examinations, elevation of ferritin, leukopenia, and positivity for anti-nuclear antibodies were frequently observed. Twelve patients underwent biopsy and 23 cases were diagnosed by radiological findings. The mean duration of hospitalization for all cases was 7.9±2.9 days (range, 3 to 13 days) and steroids were administered in 10 cases. KFD recurrence was observed in 2 cases (5.7%) with the time to relapse of 7 months and 4 years. There were no cases with systemic lupus erythematous or other autoimmune disease. Conclusion: KFD should be considered in pediatric patients with lymphadenopathy and prolonged fever. Patients with KFD should be monitored for recurrence and the development of autoimmune disease.

두엄먹물버섯이 생산하는 섬유소 분해효소에 관한 연구

柳寬熙,柳孝林,李京昊 尙志大學校 1998 論文集 Vol.19 No.-

Cellulosic substance which plays an important role in carbon cycle is most abundant in the nature would. Some higher fungi are able to digest cellulose directly to satisfy their carbohydrate requirement. The effects of active conditions in the various substrates added Czapek's-Dox media for celluloytic enzymes activity by coprinus atramentarius were investigated. The optimum pH and temperature for enzymes activity were 5.0 and 40℃ in Cx-cellulase, 5.0 and 30℃ in C₁-cellulase, 7.0 and 20℃ in β- glucosidase, respectively. Among the various substrates added to Czapek's-Dox media, FPC media was effective to Cx-cellulase activity and PSC media was effective to C₁- cellulase and β- glucosidase activity.

청소년기 아동의 수면에 관한 조사 연구

유경희 순천향대학교 교수학습개발센터 2004 Journal of Soonchunhyang Medical Science Vol.10 No.3

Purpose : This study was to investigate sleep pattern in adolescence. Method : The subjects for this study were 160 adolescences in Seoul. The research instruments used in this study were the measures of sleep and SPSSWIN 10.0 Program was used for data analysis. Result : The adolescences went to bed after 12. p.m., but many of them felt easily falling asleep within 5 minutes. They waked up quite early at around 4 to 6 o'clock in the morning and remained in 1 hour in bed. 40.6 percent of the subjects showed their satisfaction in thier sleep. As for the quality of sleep, 4.3 percent of the subjects could not sleep deeply, 21.8 percent of the subjects waked up frequently during sleep. Conclusion : The adolescences had a deep sleep and had not difficulty in falling asleep in night. Also they had not difficulty in going back to sleep after awakening during night time sleep.

Dissolved Air Flotation(DAF) 접촉조의 수리동력학적 조건이 입자의 제거에 미치는 영향

유제선,김성훈,신은허,박희경 대한상하수도학회 2003 상하수도학회지 Vol.17 No.1

Hydrodynamic conditions for optimum solids capture within the contact zone, which are governed by the geometry and flow, are not yet well understood. In this research, dimensionless parameters which represent hydrodynamic conditions in the contact zone were derived, using the Buckingham π theorem. Those parameters are Reynolds No. (Re), Froude No. (Fr), Weber No. (We), Local Weber No., and Bubble Capacity No. (Bc). The particle removal rate was investigated by changing each value of the dimensionless parameters. The experimental results indicate that particle removal rate, when gravity dominates and the flow is semi-turbulent (Fr < 0.3, Re < 8000), is higher than when inertia dominates and flow is turbulent. For the We, higher removal rates were obtained in the range of the We < 40. Relative to the Local We, smaller bubbles which are influenced more by surface tension than inertia, demonstrated a higher particle removal rate than larger bubbles. For the Bc, the optimal range is from 0.3 to 0.5. We suggest that these dimensionless parameters can be used to diagnose the performance of and to design a DAF reactor.

흰쥐 뇌줄기에 분포하는 Nitric Oxide Synthase 신경세포에 관한 면역조직화학적 연구

나준희,허영범,박찬,김정혜,유진화,안희경,이원규 대한해부학회 1999 Anatomy & Cell Biology Vol.32 No.2

전정 자극이 미숙아의 생리적 지수에 미치는 효과

유경희 순천향대학교 교수학습개발센터 2004 Journal of Soonchunhyang Medical Science Vol.10 No.3

Purpose : This study was to evaluate the effects of providing vestibular simulation of heart rate and respiratory rate in preterm infants. Methods: The design of this study was nonequivalent control group pretest-posttest design in quasi experimental study. Thirty two preterm infants were randomly assignes to experimental and control group : 15 in the vestibular stimulation group and 17 in the control group. The criteria for inclusion in this study were 1)gestational age less than 37 week, 2) a birth weight less than 2,500g, 3) the absence of congenital anomalies, and specific diseases, 4) a recovering physiological weight loss, and 5) weraned from venitilatory assiistance or oxygen. In date analysis. SPSSWIN 10.0 program was utilized for descriptive statistics, t-test. Results: General characteristics of the two groups showed no significant difference, thus two groups were found to be homogenous. The heart rate and respiratory rate of vestibular stimulation group were not significantly reduced than control group after 10 days.

민들레 잎과 뿌리 분말을 첨가한 설기떡의 품질 특성

유경미,김세희,장정화,황인경,김경임,김성수,김영찬 한국조리과학회 2005 한국식품조리과학회지 Vol.21 No.1

In order to develop a dandelion (Taraxacum officinale) with natural food applications, the effects of dandelion leaves and roots powder content on the physical, textural and sensory properties of sulggidduk were examined. Dandelion powders of leaves and roots at 0, 1, 2 and 3% were added to the dandelion sulgidduk. In the dandelion roots powder in sulgidduk, the color intensity of L values and the values and moisture content decreased however, the sensory color intensity, dandelion flavor and overall acceptability increased with increasing the dandelion powder content. The sensory overall acceptability indicated the dandelion roots powder content at 3% had the highest overall and flavor scores. As the dandelion leaves content was increased, the moisture contents, lightness, adhesiveness and cohesiveness of sulggidduk decreased, while the sensory color intensity, sensory hardness, hardness of texture properties and dandelion flavor increased. The addition at 1% of the dandelion leaves powder content with the dandelion sulggidduk and the addition at 3% of the dandelion roots powder content with the dandelion sulggidduk showed the highest overall acceptability.

마사지 자극이 미숙아에게 미치는 효과

유경희 순천향대학교 교수학습개발센터 2004 Journal of Soonchunhyang Medical Science Vol.10 No.3

Purpose: This study was to evaluate the effects of providing skin massage for preterm infants on heart rate and respiratory rate. Methods: The design of this study was nonequivalent control group pretest-posttest design in quasi experimental study. Thirty eight preterm infants were randomly assignes to experimental and control group : 17 in the control and 21 in the massage group. The massage consisted of general body stroking fo rtwice, 10-minute periods per day for 10 days. Massage was given to 21 preterm neonates and the control group of 17 neonates recived normal nursery. In data analysis, SPSSWIN 10.0 program was utilized for descripive statistics, t-test. Results : The results of this study were as follows. 1) General characteristics of the two group showed no significant difference, thus two goups were sound to be homogenous. 2)There was significant difference in heart rate between two groups(t=-3.440, p=.002), and there were no significant differencees in respiration rate between two groups. Conclusions : The effects of general skin massage for preterm infants was to increase heart rate. In conclusion, the massage can be recommended for the promotion of general body circulation and heart rate of preterm infants who were hospitalized in neonatal intensive care unit.

모발의 부위별 분석을 통한 Methamphetamine 남용자의 복용시기 추정에 관하여

유영찬,정희선,최화경,진원택,이한선 內務部 國立科學搜査硏究所 1996 國立 科學 搜査 硏究所 年報 Vol.28 No.-

류마티스 관절염 환자의 불확실성에 대한 적응에 영향을 미치는 요인 탐색

유경희 대한류마티스 건강전문학회 2001 근관절건강학회지 Vol.8 No.2

This study was conducted to investigate the affecting factors on the adaptation to uncertainty in patients having rheumatoid arthritis. Subjects of the study constituted 222 Patients who visited outpatient of rheumatic center in Seoul. Self report Questionnaires were used to measure the variables affecting the adaptation to uncertainty. The variables affecting the adaptation to uncertainty were uncertainty, mastery, appraisal of danger, appraisal of opportunity, emotion focused coping, Problem focused coping, pain, depression and activity of daily life (ADL). Reliability coefficients of these instruments were found Cronbach's Alpha = .70∼.94. In data analysis, SPSSWIN 10.0 program was utilized for descriptive statistics. Pearson's correlation, and multiple regression analysis . The results were as follows. 1) The range of total pain scores was from 0 to 147 and the mean score of the pain in rheumatoid arthritis patients was 72.64. 2) The range of total depression scores was from 20 to 72 and the mean score of the depression in rheumatoid arthritis Patients was 39.86. 3) The range of total ADL scores was from 22 to 80 and the mean score of the ADL in rheumatoid arthritis patients was 72.56. 4) Among the independent variables, significant factors to explain the adaptation to pain in patients were danger appraisal of uncertainty(p〈.05) and emotion focused coping(p〈.05) . 5) Among the independent variables, significant factors to explain the adaptation to depression in patients were danger appraisal of uncertainty(P〈.001) , opportunity appraisal of uncertainty(p〈.001) and mastery(p〈.005). 6) Among the independent variables, significant factors to explain the adaptation to ADL in patients were mastery(p〈.001) and danger appraisal of uncertainty(P〈.05).