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        Circumportal pancreas: A report of two cases

        Tousif Kabir,Zoe Tan Zhuo Xuan,Alexander Yaw Fui Chung 한국간담췌외과학회 2019 Annals of hepato-biliary-pancreatic surgery Vol.23 No.3

        Circumportal pancreas (CP) is an unusual pancreatic anomaly occurring in 1.1 to 2.5% of individuals, where there is abnormal fusion of the uncinate process to the main pancreatic body occurring to the left of the portal vein-superior mesenteric vein (PV-SMV) junction. Since it was first described in 1987, there have only been a few reports documented in the literature. We recently encountered 2 such cases. Patient 1 was an 81-year-old man who presented with weight loss. Computed tomography (CT) scan revealed an atrophic pancreas with dilated pancreatic duct and a nodule at the head of pancreas, suspicious for a main-duct intraductal papillary mucinous neoplasm (IPMN) with malignant change. During surgery, we discovered that the uncinate process of the pancreas was completely wrapped around the SMV and fused with the main body, resulting in encasement of the PV-SMV junction. The patient also had a replaced right hepatic artery (RHA). Patient 2 was a 76-year-old man who complained of several weeks of abdominal discomfort. A CT scan showed a dilated common bile duct with a distal mass, worrisome for distal cholangiocarcinoma. Intra-operatively, he was similarly found to have union of the uncinate process of the pancreas with the main body occurring to the left of the PV-SMV confluence, with bilateral anomalous hepatic arteries. We present a brief review of the literature surrounding this condition. Although CP is usually asymptomatic, failure to recognize it may lead to serious consequences.

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        Predictors of post-hepatectomy liver failure in patients undergoing extensive liver resections for hepatocellular carcinoma

        Ken Min Chin,John Carson Allen,Jin Yao Teo,Juinn Huar Kam,Ek Khoon Tan,Yexin Koh,Kim Poh Brian Goh,Peng Chung Cheow,Prema Raj,Kah Hoe Pierce Chow,Yaw Fui Alexander Chung,London Lucien Ooi,Chung Yip Ch 한국간담췌외과학회 2018 Annals of hepato-biliary-pancreatic surgery Vol.22 No.3

        Backgrounds/Aims: To determine the prevalence of post-hepatectomy liver failure/insufficiency (PHLF/I) in patients undergoing extensive hepatic resections for hepatocellular carcinoma (HCC) and to assess the predictive value of preoperative factors for post-hepatectomy liver failure or insufficiency (PHLF/I). Methods: A retrospective review of patients who underwent liver resections for HCC between 2001 and 2013 was conducted. Preoperative parameters were assessed and analyzed for their predictive value of PHLF/I. Definitions used included the 50-50, International Study Group of Liver Surgery (ISGLS) and Memorial Sloan Kettering Cancer Centre (MSKCC) criteria. Results: Among the 848 patients who underwent liver resections for HCC between 2001 and 2013, 157 underwent right hepatectomy (RH) and extended right hepatectomy (ERH). The prevalence of PHLF/I was 7%, 41% and 28% based on the 50-50, ISGLS and MSKCC criteria, respectively. There were no significant differences in PHLF/I between RH and ERH. Model for End-Stage Liver Disease (MELD) score and bilirubin were the strongest independent predictors of PHLF/I based on the 50-50 and ISGLS/MSKCC criteria, respectively. Predictive models were developed for each of the criteria with multiple logistic regression. Conclusions: MELD score, bilirubin, alpha-fetoprotein and platelet count showed significant predictive value for PHLF/I (all p<0.05). A composite score based on these factors serves as guideline for physicians to better select patients undergoing extensive resections to minimize PHLF.

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