Poster Session : PS 0033 ; Cardiology : Impact of Metabolic Syndrome and Obesity on Clinical Outcomes After Primary Percutaneous Coronary Intervention for ST-Segment Elevation Myocardial Infarction

( Uh Jin KIM ),( Seunghun LEE ),( Myung Ho JEONG ),( Ju Han KIM ),( HyukJin PARK ),( Ji Eun KIM ),( Youngkeun AHN ),( Jong Hyun KIM ),( Shung Chull CHAE ),( Young Jo KIM ),( Seung Ho HUR ),( In Whan S 대한내과학회 2014 대한내과학회 추계학술발표논문집 Vol.2014 No.1

Background: The correlation between obesity and metabolic syndrome (MetS) remains unclear. This study aims to investigate impact of obesity phenotype on clinical outcomes with ST-segment elevation myocardial infarction (STEMI). Methods: We analyzed in-hospital mortality and major adverse cardiac events (MACE) of 2,606 obese patients who underwent primary percutaneous coronary intervention (PCI) in the Korea Acute Myocardial Infarction Registry from November 2005 to October 2010. Patients were divided into two groups: unhealthy (any of the Mets components) obesity (BMI =25 kg/m2) and healthy (none of the Mets components) obesity. Results: The unhealthy obesity group was composed of 703 patients (27%) and healthy obesity group 1,903 patients (73%). Unhealthy obesity was more frequent in female (25.9% vs. 10.1%, P<0.001) and multi-vessel disease (53.1% vs. 47.6%, P=0.012). There were no signifi cant differences in other baseline characteristics, angiographic and procedural fi ndings, and prescribed medications between two groups. The overall incidence of complications after PCI (13.1% vs. 10.7%, P=0.097) and in-hospital mortality (1.9% vs. 1.6%, P=0.521) were similar in unhealthy obesity group compared with healthy obesity group. By the multivariate Cox regression analyses, the presence of Mets in obese patients was not an independent factor for predicting the adjusted MACE rate at one-month (HR 1.19, 95% CI 0.56-2.54, P=0.645), six-month (HR 1.48, 95% CI 0.94-2.32, P=0.088), and twelve-month (HR 1.10, 95% CI 0.75-1.61, P=0.622). Conclusions: Obesity phenotype is not an independent prognostic factor for patients with STEMI who undergoing primary PCI. The risk stratifi cation by presence or absence of Mets is not useful in these patients.

Rothia aeria Infective Endocarditis: a First Case in Korea and Literature Review

Uh-Jin Kim,원은정,Ji-Eun Kim,Mi-Ok Jang,강승지,장희창,박경화,정숙인,신종희 대한진단검사의학회 2014 Annals of Laboratory Medicine Vol.34 No.4

Rothia species are pleomorphic gram-positive bacteria that belong to the Micrococcaceae family [1]. The Rothia genus presently comprises 6 named species, 2 of which are deemed clinically relevant: Rothia dentocariosa and Rothia mucilaginosa [2-6]. Another member of the genus, Rothia aeria, a taxon group provisionally named R. dentocariosa genomovar II, is a rare cause of human infections [2, 7] To date, only 6 cases of human infection caused by R. aeria have been reported, including bacteremia [8], neck abscesses [9], respiratory tract infection [10, 11], septic arthritis [12], and infective endocarditis [13]. Although Rothia species have rarely been reported as a causative pathogen of infective endocarditis, no case has been reported in Korea. Moreover, the risk factors for invasive infection by R. aeria are not well defined because of its rarity and the difficulty of correct species identification. Here, we report a case of infective endocarditis caused by R. aeria in a patient taking tumor necrosis factor (TNF)-α blocker.

Observaciones sobre el uso de las f?rmulas de tratamiento pronominales en el espa?ol de Chile

Uh-sung Kim 한국스페인어문학회 2006 스페인어문학 Vol.0 No.41

El presente artículo tiene como fin describir las fórmulas de tratamiento pronominales que en el español de Chile se usan entre los jóvenes cultos. La base de este estudio es una encuesta sociolingüística aplicada a 40 estudiantes universitarios de la ciudad de Santiago de Chile en noviembre de 2005. La encuesta fue realizada mediante un cuestionario distribuido por el propio investigador en la Universidad de Santiago. Los resultados del análisis de la encuesta sociolingüística sobre las fórmulas de tratamiento pronominales de los jóvenes cultos chilenos corroboran las afirmaciones impresionistas hechas por Morales (1972, 1999) y Torrejón (1986, 1991) de que el sistema de tratamiento pronominal chileno se encuentra en estado de transición, y entre los jóvenes cultos ha ido ganando terreno el voseo verbal sobre el tuteo. Con el uso generalizado del voseo verbal en el español de Chile, se está formando un sistema de tratamiento pronominal, -por lo menos, entre los jóvenes cultos-, constituido por una forma de formalidad, el usted frente a dos menos formales, el tú y el vos. Con el usted se marca el respeto o la distancia, en tanto que con el vos se expresan la confianza y la informalidad. El tú se emplea como una fórmula de confianza o formalidad intermedia

Observaciones sobre el uso de las f?rmulas de tratamiento de los j?venes guatemaltecos

Uh-sung Kim 한국스페인어문학회 2005 스페인어문학 Vol.0 No.37

Este trabajo tiene como objetivo describir las formas de tratamiento tanto pronominales como nominales que emplean los jóvenes en el español de Guatemala. La base de este estudio es una encuesta sociolingüística realizada a 42 estudiantes universitarios de la ciudad de Guatemala en 2005. Los resultados del análisis de la encuesta sociolingüística indican que Guatemala cuenta con un sistema de formas pronominales triádico, el cual está constituido por una forma de respeto el usted frente a dos menos formales, el tú, y el vos. Con el usted se marca el respeto o la distancia, en tanto que con el vos se marca la confianza y la informalidad. El tú se utliza como una fórmula de confianza o formalidad intermedia. Los factores más importantes que influyen en la selección de las formas de tratamiento son la edad, la confianza y el sexo del interlocutor. Para las personas mayores, es común usar el usted. Aun en el trato con familiares donde prevalece el uso del vos y el tú, cuando hay diferencia de edad, en general se usa la forma de respeto, el usted. Entre los hombres se observa que la forma de trato varía, dependiendo del sexo de los interlocutores. Los varones tienden a hablar de vos a los interlocutores de igual edad y del mismo sexo, pero a los de la misma edad y del sexo opuesto tienden a dirigirse de tú. Para el trato con la novia, el tuteo es predominante.

Verifying Calibration Effectiveness and Simulation Exactness in Comparison between Measurement and Simulation on Optical Properties in Integrating Sphere

Uh-Chan Ryu,Yong Wook Lee 한국조명·전기설비학회 2017 조명·전기설비학회논문지 Vol.31 No.8

In measuring optical properties of lighting with a colored surface using an integrating sphere, it is necessary to calibrate out the variations caused by the surface color as recommended in the IES LM-79-08. Assuming hemispheres as non-fluorescent surfaces of test samples such as LED lamps, LED luminaires, etc., the sizes and the colors of the hemispheres are changed to give variations of the optical properties tested in the integrating sphere. Real measurement data and simulation results for a 0.5-m diameter integrating sphere were compared to give another simulation for a 2-m diameter integrating sphere. Calibration effectiveness will be shown in terms of total luminous flux (TLF), xy color coordinates, correlated color temperature (CCT) and color rendering index (CRI) in a 0.5-m diameter integrating sphere. As the hemisphere diameters are increased from 3cm to 20cm and those colors are varied, TLF decreased up to 61%, and CCT increased from 3452K to 4366K. CRI was raised by 11 without calibration. The deviations of TLF, CCT and CRI were decreased to less than 5%, 22K and 0, respectively, with the calibration procedure, even if the hemisphere sizes were increased up to 0.2m. This implies that a proper calibration procedure for an integrating sphere assures accurate measurement for large-sized samples.

Observaciones sobre el uso de Las formas pronominales de tratamiento de Los jovenes mexicanos

( Uh Sung Kim ) 한국스페인어문학회 2011 스페인어문학 Vol.0 No.61

La presente investigacion se realizo para describir las formas pronominales que en el espanol de Mexico se usan entre los jovenes universitarios. Para la obtencion de datos se realizo una encuesta a 20 jovenes mexicanos cuya edad oscilo entre los 18 y 28 anos. Las encuestas se llevaron a cabo en el 2006 con la ayuda de un cuestionario elaborado por el propio investigador. Los resultados del analisis de la encuesta sociolinguistica indican que en el sistema de tratamiento pronominal de Mexico el tuteo esta generalizado para las relaciones solidarias, y el uso de usted es predominante en las relaciones no solidarias, donde hay distancia (edad, estatus) entre los interlocutores. Dentro del ambito familiar, el tuteo es la norma obligatoria para casi todas las relaciones. Y fuera del ambito familiar, el tuteo se usa generalmente en las relaciones de solidaridad, en cambio en las relaciones de poder se registra el uso cada vez mayor de la forma pronominal usted. Los factores mas significativos que influyen en la eleccion de las formas pronominales de tratamiento fuera del grupo familiar, son la edad y el estatus que tiene el destinatario.

Production of Monoclonal Antibodies by Hybridoma Techniques and Their Useful Applications

(Uh Ho Kim) 강원대학교 농업과학연구소 1984 강원 농업생명환경연구 Vol.1 No.-

ADAM33 gene polymorphisms are associated with the risk of idiopathic pulmonary fibrosis.

Uh, Soo-Taek,Jang, An-Soo,Park, Sung-Woo,Park, Jong-Sook,Min, Chang-Gi,Kim, Yong Hoon,Park, Byung-Lae,Shin, Hyoung Doo,Kim, Dong Soon,Park, Choon-Sik Springer International 2014 Lung Vol.192 No.4

<P>Idiopathic pulmonary fibrosis (IPF) is characterized by progressive dyspnea and worsening lung function due to remodeling of the lung, including epithelial mesenchymal transition. ADAM33 is a disintegrin and metalloprotease domain-containing protein, which may be related to lung fibrosis by exerting angiogenesis and remodeling of the lung. Thus, we evaluated the association of single-nucleotide polymorphisms (SNPs) of ADAM33 with the risk of IPF.</P>

Inhibition of Vitamin D Receptor Translocation by Cigarette Smoking Extracts

Uh, Soo-Taek,Koo, So-My,Kim, Yang Ki,Kim, Ki Up,Park, Sung Woo,Jang, An Soo,Kim, Do Jin,Kim, Yong Hoon,Park, Choon Sik The Korean Academy of Tuberculosis and Respiratory 2012 Tuberculosis and Respiratory Diseases Vol.73 No.5

Background: Vitamin D can translocate a vitamin D receptor (VDR) from the nucleus to the cell membranes. The meaning of this translocation is not elucidated in terms of a role in pathogenesis of chronic obstructive pulmonary disease (COPD) till now. VDR deficient mice are prone to develop emphysema, suggesting that abnormal function of VDR might influence a generation of COPD. The blood levels of vitamin D have known to be well correlated with that of lung function in patients with COPD, and smoking is the most important risk factor in development of COPD. This study was performed to investigate whether cigarette smoke extracts (CSE) can inhibit the translocation of VDR and whether mitogen activated protein kinases (MAPKs) are involved in this inhibition. Methods: Human alveolar basal epithelial cell line (A549) was used in this study. 1,25-$(OH_2)D_3$ and/or MAPKs inhibitors and antioxidants were pre-incubated before stimulation with 10% CSE, and then nucleus and microsomal proteins were extracted for a Western blot of VDR. Results: Five minutes treatment of 1,25-(OH2)D3 induced translocation of VDR from nucleus to microsomes by a dose-dependent manner. CSE inhibited 1,25-$(OH_2)D_3$-induced translocation of VDR in both concentrations of 10% and 20%. All MAPKs inhibitors did not suppress the inhibitory effects of CSE on the 1,25-$(OH_2)D_3$-induced translocation of VDR. Quercetin suppressed the inhibitory effects of CSE on the 1,25-$(OH_2)D_3$-induced translocation of VDR, but not in n-acetylcysteine. Conclusion: CSE has an ability to inhibit vitamin D-induced VDR translocation, but MAPKs are not involved in this inhibition.

The Survival Rate of Korean Patients with COPD with or without Acute Exacerbations

Uh, Soo-Taek,Lee, Ji-Yeon,Koo, So-Mi,Kim, Yang-Ki,Kim, Ki-Up,Park, Jong-Sook,Park, Sung-Woo,Jang, An-Soo,Kim, Do-Jin,Choi, Jae-Sung,Na, Joo-Ok,Suh, Ki-Hyun,Kim, Yong-Hoon,Park, Choon-Sik The Korean Academy of Tuberculosis and Respiratory 2011 Tuberculosis and Respiratory Diseases Vol.70 No.6

Background: Chronic obstructive pulmonary disease (COPD) is characterized by air low limitation, which is one of the leading causes of mortality worldwide. There have been many studies on survival rates in the world literature, but there have been few reports regarding the survival rate in Korean patients with COPD. Acute exacerbation is regarded as a risk factor for mortality in patients with COPD. The purpose of this study was to investigate the survival rate and the effect of acute exacerbations on the survival rate of Korean patients with COPD. Methods: A total of 502 COPD patients who were diagnosed on the basis of history and lung function tests were enrolled in this study. The frequency of acute exacerbations, body mass index (BMI), C-reactive protein (CRP) and pulmonary hypertension were analyzed. Results: The 3- and 5-year survival rates were 98% and 83%, respectively. The median survival time was 78 months. The median survival time was 55 months in 322 patients with one or more acute exacerbations. The 3- and 5-year survival rates were significantly lower in the 322 patients with one or more acute exacerbations than in those without any. The mortality rate was significantly higher in patients with CRP>3 mg/L than in those with CRP ${\leq}3$ mg/L (p<0.005); it was significantly higher in patients with pulmonary hypertension than in those without it (p<0.01). Conclusion: Because the 5-year survival rate is 83% in Korean patients with COPD, the management of stable patients with COPD should focus on the prevention of acute exacerbations.