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RISS 인기검색어
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- 저자 : Xuelan Chen (검색결과 4 건)
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Qiping Chen,Xuelan Yang 대한기계학회 2014 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.28 No.8
To improve the efficiency and life of in-wheel motor in micro-electric vehicle, thermal loss and temperature field are calculated andanalyzed. The mathematical model of thermal loss and temperature field was established, the equivalent model of stator winding wasadequately handled, convection heat transfer coefficients was calculated, and the heat distribution of in-wheel motor was analyzed. Winding copper loss, stator and rotor core loss and eddy current loss of permanent magnet were calculated, which were coupled to thetemperature field as the heat sources. This paper effectively simplified and dealt with the inner complex radiating coefficient. Threedimensionalfinite element model of temperature field was established, and static and transient state temperatures were simulated andanalyzed. Overall temperature of the stator region is higher than that of the rotor region. Temperature of stator iron core is basically accordwith the temperature of equivalent insulating film, but both are less than the temperature of equivalent winding. The conformity ofthe measurement results with the final simulation results shows that three-dimensional finite element method is accurate and feasible toanalyze thermal loss and temperature distribution of in-wheel motor, which can afford a theoretical basis to optimize the in-wheel motor.
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Zheng Chen,Xueying Zhao,Shuwei Wei,Dengfeng Wang,Xuelan Zhang,Jianfeng Shan 한국화학공학회 2022 Korean Journal of Chemical Engineering Vol.39 No.11
In the industrial production, water exists inevitably into feed stocks in the form of impurity, and it can produce a negative effect in the hydrogenation reaction due to the preferential adsorption of water on active sites. Here, the surfactants (polyvinylpyrrolidone, poloxamer, polyethylene glycol and hexadecyl trimethyl ammonium bromide) are used to improve physicochemical property of Cu/SiO2 catalysts, so that Cu/SiO2 catalysts had a good hydrogenation performance at condition containing water. The appropriate addition amount of surfactants in the catalyst preparation process effectively hindered the agglomeration of copper species by steric configuration and repulsion effect between Cu2+ and positive ionizable, which brought about high copper dispersion and small particle size. Meanwhile, the decomposition of surfactants produced many pores during calcination, resulting in the increased of specific surface area and average pore diameter. These advantages provided more chances for reactants to touch active sites due to spatial restriction and the increase of the number of active sites, so that the negative effects of water can be counteracted. The conversion of Cu/SiO2 catalysts, that the surfactants was added in the catalyst preparation process, increased 60% to 200% at reaction condition containing water.
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Yong Ye,Haiting Xing,Xuelan Chen 대한약학회 2013 Archives of Pharmacal Research Vol.36 No.8
The defatted seeds of Camellia oleifera (Abel.)are used for stopping itching and pain in old days, theeffective compounds need to be investigated. Sasanquasaponinas a rich fraction was extracted with 70 % ethanol,purified by AB-8 macro-reticular resin, crystallized in 80 %ethanol, and further hydrolyzed by 4 % hydroxyl potassiumor 2 M hydrochloride. Anti-inflammatory activities of theextracts were measured by carrageenan-induced paw edemain rats and croton oil induced ear inflammation in mice; theanalgesic activities were analyzed by hot plate test, aceticacid induced writhing in mice; the levels of pain mediatorsof IL-1b, TNF-a and PGE2 were determined; the antioxidativeactivities in vivo were evaluated by MDA, SOD andGSH-Px in serum of rats. The extracts showed significant(p\0.01) anti-inflammatory and analgesic activities,remarkably (p\0.01) inhibited production of pro-inflammatorycytokines and PGE2, decreased MDA and increasedSOD and GSH-Px in serum. Inhibition of IL-1b, TNF-a andPGE2 may contribute to their anti-inflammatory and analgesiceffects; elimination of free radicals is also involved. The sapogenin and acid hydrolyzed product have betteranti-inflammatory, analgesic effects, and stronger antioxidativeactivity than sasanquasaponin and alkaline hydrolyzedproduct, and they are better candidate medicines forinflammation and pain.
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Yong Ye,Mingyang Li,Xuelan Chen 대한약학회 2013 Archives of Pharmacal Research Vol.36 No.4
Venom of Agkistrodon halys Pallas can controlsevere pain such as cancer pain and neuropathic pain, but itis made up of complicated components. Aim of this studyis to separate major analgesic fraction from venom ofA. halys Pallas, and to reveal its biochemical and pharmacologicalproperties. Three steps with ion exchangecolumn first and molecular sieve columns next were usedto separate and purify the fractions of venom. Analgesiceffects were evaluated by hot plate tests and writhing testsin mice. The molecular weight (MW), isoelectric point,amino acid sequence, purity were respectively determinedby SDS-PAGE electrophoresis, isoelectric focusing,Edman degradation and HPLC. The dependence and tolerancewere observed by withdrawal test in rats, andanalgesic effects were observed in mice during 7 daysadministration. Fourteen fractions were obtained by separation;the best analgesic fraction named Pallanalgesinwas selected by ED50 and LD50. It had single band inelectrophoresis, relative purity 92.16 %, MW 16.6 kDa,isoelectric point 8.8, and former sequence of ten aminoacids H-L-L-Q-F-R-K-M-I-K. It showed significant analgesiceffect without tolerance and dependence. As a novelanalgesic, Pallanalgesin has been found to explain thefunction of venom of A. halys Pallas on severe pain controlin traditional uses.
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