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Wenling Chen,Yong Jiang,Rong Qiu,Wu Xu,Yanbei Hou 한국고분자학회 2020 Macromolecular Research Vol.28 No.1
Dense smoke released during the combustion of polystyrene (PS) potentially limits its applications in some fields. In this study, a Zr-based metal-organic framework (UiO-66) was prepared via the solvothermal method and added to PS to suppress its smoke emission. Well-defined UiO-66 particles showed an excellent dispersion state and good compatibility in the PS matrix. The introduction of UiO-66 improved the flame retardancy and smoke suppression of PS. The peak heat-release rate and total heat release were reduced by 26.8% and 14.7%, respectively, for PS/ UiO-66-5 wt%. Moreover, the smoke emissions of PS composites were evidently suppressed, and more than a 35% reduction in total smoke production was obtained with 5-wt% UiO-66. Through the analysis of the residues and pyrolysis products of PS composites, the mechanisms of enhanced flame retardancy and smoke suppression can being speculated as the promoted char-forming and heat barrier of UiO-66. This work offers a significant reference for the further study of UiO-66 and polymer materials.
Cheng Han Ng,Kai En Chan,Yip Han Chin,Rebecca Wenling Zeng,Pei Chen Tsai,Wen Hui Lim,Darren Jun Hao Tan,Chin Meng Khoo,Lay Hoon Goh,Zheng Jye Ling,Anand Kulkarni,Lung-Yi Loey Mak,Daniel Q Huang,Mark C 대한간학회 2022 Clinical and Molecular Hepatology(대한간학회지) Vol.28 No.3
Background/Aims: Nonalcoholic fatty liver disease (NAFLD) is closely associated with diabetes. The cumulative impact of both diseases synergistically increases risk of adverse events. However, present population analysis is predominantly conducted with reference to non-NAFLD individuals and has not yet examined the impact of prediabetes. Hence, we sought to conduct a retrospective analysis on the impact of diabetic status in NAFLD patients, referencing non-diabetic NAFLD individuals. Methods: Data from the National Health and Nutrition Examination Survey 1999–2018 was used. Hepatic steatosis was defined with United States Fatty Liver Index (US-FLI) and FLI at a cut-off of 30 and 60 respectively, in absence of substantial alcohol use. A multivariate generalized linear model was used for risk ratios of binary outcomes while survival analysis was conducted with Cox regression and Fine Gray model for competing risk. Results: Of 32,234 patients, 28.92% were identified to have NAFLD. 36.04%, 38.32% and 25.63% were non-diabetic, prediabetic and diabetic respectively. Diabetic NAFLD significantly increased risk of cardiovascular disease (CVD), stroke, chronic kidney disease, all-cause and CVD mortality compared to non-diabetic NAFLD. However, prediabetic NAFLD only significantly increased the risk of CVD and did not result in a higher risk of mortality. Conclusions: Given the increased risk of adverse outcomes, this study highlights the importance of regular diabetes screening in NAFLD and adoption of prompt lifestyle modifications to reduce disease progression. Facing high cardiovascular burden, prediabetic and diabetic NAFLD individuals can benefit from early cardiovascular referrals to reduce risk of CVD events and mortality.