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Osman Raif Karabacak,Fatih Yalçınkaya,Uğur Altuğ,Nurettin Sertçelik,Fuat Demirel 대한비뇨의학회 2014 Investigative and Clinical Urology Vol.55 No.9
Purpose: To evaluate the efficacy of subureteral injection types in patients with middletohigh-grade vesicoureteral reflux (VUR). Materials and Methods: Between June 1999 and September 2010, subureteral dextranomerwas applied at our clinic to 149 patients (214 refluxing ureters) with grades II,III, and IV VUR. Group 1 consisted of 54 patients (80 ureters), and group 2 consistedof 95 patients (134 ureters). The standard subureteric transurethral injection (STING)procedure was applied to group 1, and the modified STING procedure was applied togroup 2. A second and if needed a third injection was applied to unsuccessfully treatedpatients. The mean follow-up period was 2 years. Patients were evaluated by cystographyand ultrasonography in the third month of follow-up. Results: VUR was resolved completely after a single injection in 54/80 ureters (67.5%)in group 1 and in 94/134 ureters (70.1%) in group 2. Overall successes after a secondor a third injection were 61/80 (76.2%) and 111/134 (82.8%), respectively. There wasa statistically significant difference between the groups only for grade IV reflux followingmultiple injections (p<0.05). Conclusions: Endoscopic treatment of VUR is a recommended treatment because it isminimally invasive, efficient, and repeatable. Our study confirmed that a modifiedSTING procedure can be an alternative treatment to the standard technique.