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Azizi, Alexander A.,Mohan, Anita T.,Tomouk, Taj,Brickley, Elizabeth B.,Malata, Charles M. Korean Society of Plastic and Reconstructive Surge 2020 Archives of Plastic Surgery Vol.47 No.4
Background The deep inferior epigastric artery perforator (DIEP) flap is the commonest flap used for breast reconstruction after mastectomy. It is performed as a unilateral (based on one [unipedicled] or two [bipedicled] vascular pedicles) or bilateral procedure following unilateral or bilateral mastectomies. No previous studies have comprehensively analyzed analgesia requirements and hospital stay of these three forms of surgical reconstruction. Methods A 7-year retrospective cohort study (2008-2015) of a single-surgeon's DIEP-patients was conducted. Patient-reported pain scores, patient-controlled morphine requirements and recovery times were compared using non-parametric statistics and multivariable regression. Results The study included 135 participants: unilateral unipedicled (n=84), unilateral bipedicled (n=24) and bilateral unipedicled (n=27). Univariate comparison of the three DIEP types showed a significant difference in 12-hour postoperative morphine requirements (P=0.020); bipedicled unilateral patients used significantly less morphine than unipedicled (unilateral) patients at 12 (P=0.005), 24 (P=0.020), and 48 (P=0.046) hours. Multivariable regression comparing these two groups revealed that both reconstruction type and smoking status were significant predictors for 12-hour postoperative morphine usage (P=0.038 and P=0.049, respectively), but only smoking, remained significant at 24 (P=0.010) and 48 (P=0.010) hours. Bilateral reconstruction patients' mean hospital stay was 2 days longer than either unilateral reconstruction (P<0.001). Conclusions Although all three forms of DIEP flap breast reconstruction had similar postoperative pain measures, a novel finding of our study was that bipedicled DIEP flap harvest might be associated with lower early postoperative morphine requirements. Bilateral and bipedicled procedures in appropriate patients might therefore be undertaken without significantly increased pain/morbidity compared to unilateral unipedicled reconstructions.
Numerical study of laminar-forced convection of Al2O3 -water nanofluids between two parallel plates
M. Hemmat Esfe,A. A. Abbasian Arani,T. Azizi,S. H. Mousavi,S. Wongwises 대한기계학회 2017 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.31 No.2
Laminar-forced convection of Al 2 O 3 -water nanofluid between two parallel plates was studied numerically. The channel walls were assumed to be isothermal. The effective viscosity and thermal conductivity of nanofluid were considered as variables, and the effects of applying a variable properties model were investigatedby using two relatively new models. The numerical results were compared to the results obtained from a previous non-variable properties model. Also, the effects of nanoparticle size on the flow and heat transfer within the channel were investigated. The study was carried out using Reynolds numbers between 100-1000, nanoparticle diameters in the 15-75 nm range, and nanoparticle volume fractions in the range 0.01-0.05 nm. The numerical results show that using nanofluid could enhance heat transfer by up to 35 %, compared to the base fluid. In addition, reducing the nanoparticle diameter can enhance heat transfer by up to 15.9 %.