Effects of dietary supplementation with probiotic CS-A on performance in broiler chickens

Seong Soo Kang1*, Se Eun Kim, Ara Go, Kyung Mi Shim, Chun Sik Bae, Chang Jong Moon, Sung-Ho Kim, Jong-Choon Kim, Jin-Cheol Yoo, Seung Sik Cho 충북대학교 동물의학연구소 2012 Journal of Biomedical and Translational Research Vol.13 No.3

Probiotics, enzymes, organic acids, oligosaccharides, antioxidants, and other functional materials are actively being explored as alternatives to antibiotics. Probiotics include live beneficial microorganisms that colonize the intestinal tract and competitively inhibit attachment and growth of harmful microbes. Probiotics also increase feed efficiency by assisting in nutrient absorption and digestion. The current study was conducted in order to evaluate the effect of a new probiotic, CS-A, as a dietary supplement of a fermented product on growth performance, feed intake, and feed conversion efficiency in broiler chickens, and to evaluate its value as an alternative for antibiotics used as a feed additive. Antibacterial and anti-inflammatory effects of CS-A were investigated in vitro and the in vivo effects of a constant concentration of supplemented CS-A on growth rate and feed efficiency were evaluated. In addition, the safety of CS-A was assessed by examination of common symptoms and mortality. Determination of minimal inhibitory concentration revealed an excellent antibacterial effect of CS-A. Cytotoxicity was low and anti-inflammatory effects were achieved at the effective concentration of CS-A. Supplementation with 0.1% CS-A resulted in a feed efficiency score of 1.84 in broilers, compared to 2.00 in the control group. There were no adverse clinical findings, necropsy findings, hematology, and altered serum biochemistry parameters, and no mortality. Thus, it is concluded that CS-A is safe and effective as a feed additive.

급성 심근경색 후 심인성쇽의 발생에 관여하는 위험인자

전두수(Doo Soo Jeon),정해억(Hae Uk Chung),승기배(Ki Bae Seung),강동헌(Dong Hun Kang),김상우(Sang Wo Kim),김용주(Young Ju Kim),채장성(Jang Sung Chae),김재형(Jae Hyung Kim),홍순조(Soon Jo Hong),최규보(Kyu Bo Choi) 대한내과학회 1996 대한내과학회지 Vol.50 No.6

Objectives: Cardiogenic shock resulting from acute myocardial infarction is a serious complication with high mortality. The early identification of patients at high risk of developing post-infarction cardiogenic shock might allow early intervention in an attempt to prevent cardiogenic shock and to reduce the mortality due to cardiogenic shock. The aim of the present study was to examine the risk factors of inhospital development of cardiogenic shock among patients with acute myocardial infarction. Methods: We studied 152patients with acute myocardial infarction who were admitted to Kang-Nam St. Mary's hospital within 24hours after the onset of chest pain and did not have cardiogenic shack on admission between March 1991 and May 1994. Clinical data of these patients were analyzed. Results: Of 152patients, 17(11.1%) developed cardiogenic shock during their hospital stay. Cardiogenic shock developed in 53% of cases more than 24hours after admission. 82.4% of patients with cardiogenic shock died whereas a 6.7% in-hospital mortality was found among patients without cardiogenic shock. Multivariate regression analysis that controlled for variables affecting incidence of postinfarction cardiogenic shock showed that independent risk factors for in-hospital cardiogenic shock were history of myocardial infarction (adjusted relative odds[RO]=5.294, 95% confidence interval[CI]=2.149 to 13.041); heart failure on admission (RO=3.344, 95% CI=1.738 to 6.432); hyperglycemia (>180mg/dl) in non-diabetic patients (RO=3.270, 95% CI=1,590 to 6.727); age over 70 year old (RO=2.912, 95% CI= 1.816 to 4.668); ST deviation over 4mm (RO=2.417, 95% CI=1.225 to 4.767); peak LDH level greater than 1600U/ml (RO=1.154, 95% CI=1.080 to 1.233). Patients with one independent risk factor had an estimated probability of 10.5% for developing inhospital cardiogenic shock; patients with two independent risk factors, 48.5%, patients with three risk factors, 65.0% patients with four risk factors, 65.7% patients with five risk factors, 67.2%. Conclusion: Of post-infarction cardiogenic shock during admission, 53% developed more than 24hours after admission. The more independent risk factors on admission for inhospital cardiogenic shock patients with acute myocardial infarction had, the more likely in-hospital cardiogenic shock developed.

외과영역 복강경수술의 임상치험

강동수(Dong Soo Kang),최상용(Sang Yong Choi),이광찬(Kwang Chan Lee),김진승(Chin Seung Kim) 대한소화기학회 1993 대한소화기학회지 Vol.25 No.5

N/A The 19 months clinical experiences about 634 cases of laparoscpic surgery were reviewed at Sung-Ae General Hospital from July 1991 to Jan. 1993 The results were as follows; Among 168 cases of laparoscopic cholecystectomy and 5 cases of laparoscopic CBD exploration, we obtained better results with advantages of laparoscopic surgery including few complications, less morbidity and early return to work. In series of 361 cases of laparoscopic appendectomy, we obtained superior results especially in the cases of 1) uncertainty of clinically suspected appendicitis, 2) right lower quadrant pelvic pain without other pathology and 3) patients who wanted early return to work. In series of spontaneous pneumothorax with bullae and recurrent pneumothorax, the thoracoscopic bullectomy was much superior than open bullectomy. The laparoscopic Taylor procedures and laparoscopic bandlysis will be better choice in the management of intractable pain in duodenal ulcer and postoperative adhesion. The diagnostic laparoscopy will be much useful in the blunt and penetrating abdominal trauma.

단상 멀티레벨 능동전력필터를 위한 고조파 검지 기법 비교

김윤호(Yoon-Ho Kim),김수홍(Soo-Hong Kim),김성민(Sung-Min Kim),서강문(Kang-Moon Seo) 전력전자학회 2005 전력전자학술대회 논문집 Vol.- No.-

In this paper, harmonic detecting methods for the active power application are investigated. They are RDFT, Kalman Filter, Adaptive predictive filter, Instantaneous reactive power detecting method, Improved adaptive filter detecting method. The 5 harmonic detecting methods are simulated and their characteristics for the active filter application are compared using simulation results.

<SUP>18</SUP>F-FDG PET-CT에서 진단된 갑상선 우연종의 악성종양 발견율 및 특징

이강영,고건<SUP>1<.SUP>,김선국<SUP>1<.SUP>,고진철<SUP>1<.SUP>,김행수,최상용,박신희,박용휘<SUP>2<.SUP>,Kang Young Rhee,Gun Koh,<SUP>1<.SUP>,Sun Kuk Kim,<SUP>1<.SUP>,Jin Chul Koh,<SUP>1<.SUP>,Haeng Soo Kim,Sang Yong Choi,Shin 대한갑상선-내분비외과학회 2008 The Koreran journal of Endocrine Surgery Vol.8 No.1

<B>Purpose: </B>PET-CT is often used to differentiate benign or malignant thyroid incidentalomas. In this retrospective study, we evaluated whether the <SUP>18</SUP>F-FDG uptake pattern and PET-CT findings improved accuracy over the standardized uptake value (SUV). <B>Methods:</B> <SUP>18</SUP>F-FDG PET-CT was performed on 2,178 subjects from August, 2004, to October, 2007, in Sung-ae Hospital. PET-CT was performed on 806 patients (37%) with suspected or known nonthyroidal cancer and 1,372 healthy subjects (63%) without a previous history of cancer. We investigated the clinical characteristics of patients, history, standardized uptake value (SUV), ultrasonography, and hormone levels in blood. Thyroidal cancer was confirmed by ultrasonography-guided fine needle aspiration and pathology after thyroid operation. <B>Results:</B> The prevalence of focal thyroid lesions on PET-CT was 8.8% (191/2178). Thyroid cancer confirmation was 7.9% (15/191). The maximum SUV of malignant thyroid lesions were significantly higher than that of benign lesions (7.00±3.08 vs. 4.49±1.84, P<0.001). <B>Conclusion:</B> PET-CT image interpretation that includes 18F-FDG uptake and SUV is better than PET-CT alone for differentiating benign and malignant lesions. Thyroid cancer risk increases as SUVmax levels increase. <B>(Ko</B><B></B><B>rean J Endocrine Surg 2008;8:38-42)</B>

Temperature dependence of the photocurrent in Ge1−x Sn x layers

Kang, Sukill,Kil, Yeon-Ho,Jeong, Tae Soo,Choi, Chel-Jong,Shim, Kyu-Hwan,Kim, Dae-Jung,Choi, Yong-Dae,Kim, Taek Sung 한국물리학회 2016 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol. No.

<P>The temperature dependence of the photocurrent in Ge1-x Sn (x) layers was measured for different Sn compositions (0.00 a parts per thousand currency sign x a parts per thousand currency sign 0.83%). As the Sn composition in the Ge1-x Sn (x) layer increased, the photocurrent peak was clearly red shifted in comparison with that of Ge. As the measurement temperature was increased, the photocurrent peak was also clearly red shifted. The measured temperature dependence of the energy band gap was nicely fitted by using Varshni's empirical expression. Temperature-dependent bowing parameters were fitted for the equation relationship.</P>

Oxygen-carrier selection and thermal analysis of the chemical-looping process for hydrogen production

Kang, Kyoung-Soo,Kim, Chang-Hee,Bae, Ki-Kwang,Cho, Won-Chul,Kim, Sung-Hyun,Park, Chu-Sik Elsevier 2010 INTERNATIONAL JOURNAL OF HYDROGEN ENERGY - Vol.35 No.22

<P><B>Abstract</B></P><P>The three-reactor chemical-looping process (TRCL) for the production of hydrogen from natural gas is quite attractive for both CO<SUB>2</SUB> capture and hydrogen production. The TRCL process consists of a fuel reactor, a steam reactor and an air reactor. In the fuel reactor, natural gas is oxidized to CO<SUB>2</SUB> and H<SUB>2</SUB>O by the lattice oxygen of the oxygen carrier. In the steam reactor, the steam is reduced to hydrogen through oxidation of the reduced oxygen carrier. In the air reactor, the oxygen carrier is fully oxidized by air. In this process, the oxygen carrier is recirculated among the three reactors, which avoids direct contact between fuel, steam and air. In this study, various candidate materials were proposed for the oxygen carrier and support, and a thermal analysis of the process was performed. The oxygen carrier for the process must have the ability to split water into hydrogen in its reduced state, which is a different chemical property from that of the chemical-looping combustion medium. The selection of the oxygen carrier and support require careful consideration of their physical and chemical properties. Fe<SUB>2</SUB>O<SUB>3</SUB>, WO<SUB>3</SUB> and CeO<SUB>2</SUB> were selected as oxygen carriers. Thermal analysis indicated an expected hydrogen production of 2.64 mol H<SUB>2</SUB> per mol CH<SUB>4</SUB> under thermoneutral process conditions. The results indicated that hydrogen production was affected mainly by the steam-conversion rate. The solid-circulation rate and temperature drop in the fuel reactor were calculated for the selected oxygen carriers with different metal oxide contents and solid-conversion rates.</P>

Tethered Cord Syndrome; Surgical Indication, Technique and Outcome

Kang, Joon-Ki,Lee, Kwan-Sung,Jeun, Sin-Soo,Kang, Seok-Gu,Lee, Il-Woo,Yoon, Kang-Jun,Ha, Sang-Soo The Korean Neurosurgical Society 2007 Journal of Korean neurosurgical society Vol.42 No.2

Objective : The authors tried to reveal some unique features of lipomeningomyelocele (LMMC), including clinical presentation, factors precipitating onset of symptoms, pathologic entities of LMMC associated with tethered cord syndrome, and surgical outcome in LMMC patients. Methods : Seventy-five patients with LMMC were enrolled in this study. Neuro-imaging and intraoperative findings allowed classification of LMMC into three Types. The patients were divided into two groups by age : A (51 patients), from birth to 3 years, and B (24 patients), from 3 to 24 years. For prevention of retethering of the cord, a mega-dural sac rebuilding procedure was performed in 15 patients. Results : During a mean postoperative follow-up period of 4 years, the surgical outcome was satisfactory in terms of improved pain and motor weakness, but disappointing with reference to the resolution of bowel and bladder dysfunction. Among these 75 patients with LMMC, preoperative deficits were improved after surgery in 29 (39%), remained stable in 28 (37%), changed slightly in 13 (17%), and worsened in 5 (7%). Patients in group A achieved better outcomes than those in group B. Depending on the type of lesion, patients with types I and II LMMC have better outcomes than those with type III LMMC. Finally, retethering of the cord with neurological deterioration occurred in 4 (5.3%) of the 75 patients, but no retethering was found in the 15 patients who were recently treated with a mega-dural sac rebuilding procedure. Conclusion : Our data continue to support the opinion that early diagnosis and optimal surgery are still essential for the treatment of patients with LMMC, since there is a high likelihood of residual neurological functions that can be preserved. Based on our surgical experience of untethering and decompression of lipomas, a mega-dural sac repair is useful to prevent retethering of the cord.

Phosphorylation Patterns of the Hypothalamic Proteins : Effects of Forskolin , Phorbol Ester and Ovarian Steroids

Kang, Hae Mook,Kim, Kyung Jin,Cho, Wan Kyoo,Lee, Byung Ju,Kang, Sang Soo,Cho, Byung Nam 한국유전학회 1989 Genes & Genomics Vol.11 No.4

Present study aims to clarify the phosphorylation patterns of proteins derived from the rat hypothalamus pretreated with forskolin and phorbol ester in vitro or ovarian steroids in vivo. Proteins were employed to cell free phosphorylation with γ-^(32) P-ATP, analysed by SDS-polyacryl-amide gel electrophoresis and autoradiography. Treatments of forskolin and phorbol ester resulted in intensifying the specific phosphorylation bands of 43 Kd and 130 Kd, respectively, In vivo treatment of ovarian teroids such as estrogen and/or progesterone were highly effective in modifying the phosphorylation patterns of hypothalamic proteins. Furthermore, changes in protein phosphorylation by forskolin, phorbol ester and ovarian steroids were very similar to those with kinase activators such as cAMP, Ca^(2+)-phosphatidylserine and Ca^(2+)-calmodulin. Therefore, it appears that protein phosphorylation is an important step in regulating the trans-synaptic signal transduction in the hypothalamus.

Assessments of nutrient intake and metabolic profiles in Korean adolescents according to exercise regularity using data from the 2008 Korean National Health and Nutrition Examination Survey

Kang Ok Cho,Sang Nam Nam,Yeon Soo Kim 한국영양학회 2011 Nutrition Research and Practice Vol.5 No.1

The purpose of this study was to assess the metabolic profile and nutrient intake data in Korean adolescents according to exercise regularity using the forth Korean National Health and Nutrition Examination Survey from 2008 data. A total of 834 Korean adolescents (440 boys, 394 girls) aged 12 to 18 years were classified into exercising male (EM), non-exercising male (NM), exercising female (EF), and non-exercising female (NF) groups. EM exhibited significantly higher weight (P < 0.001), waist circumference (WC) (P < 0.01) and body mass index (BMI) (P < 0.001) than NM. EF showed significantly greater height (P < 0.01), weight (P<0.001), WC (P < 0.001), and BMI (P < 0.001) than NF. Although ratios of macronutrient intake were within the appropriate range in all groups, energy, riboflavin, vitamin C and calcium were assessed as in adequate by the nutritional adequacy ratio (NAR) in all groups. Moreover, EF and NF had inadequate intake of vitamin A and iron according to NAR, respectively. There were significant correlations between height and NAR protein (r = 0.249, P < 0.001), and mean adequacy ratio (MAR) (r = 0.177, P < 0.01), and between weight and NAR protein (r = 0.180, P < 0.01), and MAR(r = 0.136, P < 0.05) in EM. On the other hand, there were significant correlations between weight and NAR protein (r = 0.270, P < 0.01), WC and NAR protein (r = 0.271, P < 0.01), and BMI and NAR protein (r = 0.326, P < 0.01) in NM. There were significant correlations height and NAR Fe (r = 0.153, P < 0.05) in EF. However, there were no significant correlations between metabolic factors and nutritional adequacy in NF. Although we noted no significant differences in MAR between the groups, the exercising groups showed higher MAR values than the non-exercising groups. Therefore, practicing of ideal dietary behaviors appears to be induced through physical activity and regular exercise in Korean adolescents.