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        Shape-controlled synthesis of zinc nanostructures mediating macromolecules for biomedical applications

        Seyyed Mojtaba Mousavi,Gity Behbudi,Ahmad Gholami,Seyyed Alireza Hashemi,Zohre Mousavi Nejad,Sonia Bahrani,Wei-Hung Chiang,Lai Chin Wei,Navid Omidifar 한국생체재료학회 2022 생체재료학회지 Vol.26 No.1

        Zinc nanostructures (ZnONSs) have attracted much attention due to their morphological, physicochemical, and electrical properties, which were entailed for various biomedical applications such as cancer and diabetes treatment, anti-inflammatory activity, drug delivery. ZnONS play an important role in inducing cellular apoptosis, triggering excess reactive oxygen species (ROS) production, and releasing zinc ions due to their inherent nature and specific shape. Therefore, several new synthetic organometallic method has been developed to prepare ZnO crystalline nanostructures with controlled size and shape. Zinc oxide nanostructures’ crystal size and shape can be controlled by simply changing the physical synthesis condition such as microwave irradiation time, reaction temperature, and TEA concentration at reflux. Physicochemical properties which are determined by the shape and size of ZnO nanostructures, directly affect their biological applications. These nanostructures can decompose the cell membrane and accumulate in the cytoplasm, which leads to apoptosis or cell death. In this study, we reviewed the various synthesis methods which affect the nano shapes of zinc particles, and physicochemical properties of zinc nanostructures that determined the shape of zinc nanomaterials. Also, we mentioned some macromolecules that controlled their physicochemical properties in a green and biological approaches. In addition, we present the recent progress of ZnONSs in the biomedical fields, which will help centralize biomedical fields and assist their future research development.

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        Activated carbon@MgO@Fe3O4 as an efficient adsorbent for As (III) removal

        Esmaeili Hossein,Mousavi Seyyed Mojtaba,Hashemi Seyyed Alireza,Chiang Wei-Hung,Ahmadpour Abnavi Somayeh 한국탄소학회 2021 Carbon Letters Vol.31 No.5

        In this study, Fe3O4/MgO/Activated carbon composite was used to remove arsenic ion (As (III)) from aqueous media. To this end, Frangula Alnus was used to prepare activated carbon (AC) by calcination in the furnace at 700 °C for 4 h and was then used to synthesize the MgO/Fe3O4/AC composite. To study the surface properties of the composite, various analyses such as SEM, EDX/Mapping, FTIR, DLS, BET and VSM were applied. According to the BET analysis, the specifc surface area and average pore size of the Fe3O4/MgO/AC composite were obtained as 190.92 m2 /g and 7.57 nm, respectively, which showed that the aforementioned nanocomposite had a mesoporos structure with an excellent specifc surface area. Also, VSM analysis indicated that the composite had a superparamagnetic property and could be easily separated from the solution by a magnet. Moreover, the results of the As (III) sorption indicated that the highest uptake efciency was obtained 96.65% at pH=7, adsorbent dosage=0.13 g/L, t=35 min, T=45 °C and Co=6 mg/L. In addition, the pseudo-second-order model could better describe the kinetic behavior of the sorption process. Furthermore, Langmuir model was the best model to describe the equilibroium behavior of the As(III) ion sorption. Besides, according to the the thermodynamic study, enthalpy change and entropy change were obtained 58.11 kJ/mol and 224.49 J/mol.K, respectively, indicating that the sorption process was spontaneous and endothermic. According to the results, the Fe3O4/MgO/AC composite was a good adsorbent with the extraordinary properties, which can be used on an industrial scale.

      • Relationships between Breast Cancer and Common Non-Communicable Disease Risk Factors: an Ecological Study

        Abbastabar, Hedayat,Hamidifard, Parvin,Roustazadeh, Abazar,Mousavi, Seyyed Hamid,Mohseni, Shokrallah,Sepandi, Mojtaba,Barouni, Mohsen,Alizadeh, Ali Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.9

        Background: Breast cancer is one the most common cause of cancer-related deaths among women worldwide. The aims of this study were to investigate the impact of dietary factors and health status indicators on breast cancer (BC) incidence. Materials and Methods: Risk factor data (RFD) of 89,404 individuals (15-64 years old) were gathered by questionnaire and laboratory examinations through a cross sectional study from the Non-Communicable Disease Surveillance Centre (NCDSC) of Iran. BC incidences of all provinces through 2001-2006 segregated by age and gender were obtained from the Cancer Registry Ministry of Health (CRMH). Results: a significant positive relationship was seen between diabetes mellitus, fish comsupmption, percent of academic education and non-consumption of fruit, and breast cancer in women. However, non fish consumption, percent age illiteracy and taking fruit showed a significant negative relationship with the incidence of breast cancer. In addition, multiple linear regression analysis showed associations among percentage with academic education, fruit consumption and diabetes. Conclusions: We conclude that dietary factors such as fish and furit consumption, dairy products, health status indicators, academic education, and some diseases like diabetes mellitus can affect the BC incidence, although the results of ecologic studies like this must naturally be interpreted with caution.

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