소아 야뇨증에 대한 임상적 고찰

김승수,곽병곤,김영대,김우경,김영균,이종국 白中央醫療院 2005 仁濟醫學 Vol.26 No.1

Objectives: The aim of this study was to describe the clinical characteristics of enuretic children and to evaluate the efficacy of treatments. Methods: Our study subjects enrolled were 52 children with nocturnal enuresis, who visited outpatient clinic of pediatrics in Seoul Paik Hospital and Ilsan Paik Hospital, during the period from October 1998 to August 2004. The data of gender, age, family history, symptom, clinical type of enuresis and drug therapy were collected and analyzed retrospectively. Results: The male : female ratio was 2.25 : 1. The mean age at diagnosis was 6.8 years with an age range from 4.3 years to 12.5 years. Fourty five cases(86.5%) were diagnosed as primary enuresis and 7 cases(13.5%) were diagnosed as secondary enuresis. A family history of enuresis was noted in 5 cases(9.6%) including 4 cases with parental enuresis history. The accompanying urinary symptoms were urgency(11.5%), frequency (7.7%), and dysuria(2.0%). Conclusion: We found frequent occurrences of enuresis in boys and primary type and an occasional association with a family history of enuresis. The two main treatment modalities were behavior control with an alarm system and drug therapy with imipramine, desmopressin, or oxybutynin. We recommend continuous drug medications to control nocturnal enuresis along with encouragement.

4륜 2 자유도 구륜 이동 로보트의 모델링

文鍾寓,金鍾守,朴世承 조선대학교 전자정보통신연구소 2000 電子情報通信硏究所論文誌 Vol.3 No.1

본 논문에서는 4륜 2 자유도 구륜이동로보트의 기구학 및 동역학적 모델링과 경로 추적을 다루었다. 구륜이동로보트의 기구학 모델을 이용하여 구륜이동로보트의 가제어성을 살펴본다. 동역학 모델의 유도를 위해 순간 일치 좌표계, 힘/토크의 전파와 중첩 그리고 Newton의 평형법칙을 이용한다. 모델링 불확실성으로 인한 오차의 보상을 위해 제어기를 도입한다. 또한 모의실험을 통해 본 논문의 유효성을 입증한다. In this paper are presented kinematic and dynamic modeling and path-tracking of four-wheeled mobile robots with 2 d.o f Controllability of wheeled-mobile robots is revealed by using the kinematic model Instantaneously coincident coordinate system, force/torque propagation and superposition, and Newton's equilibrium law are used to induce the dynamic model The controller is introduced to compensate for error owing to modeling uncertainty And simulation results prove that method proposed by this paper is efficient

冬蟲夏草의 抗轉移와 免疫增進에 關한 硏究

최우진,유화승,이용연,서상훈,조정효,이연월,손창규,조종관 대전대학교 한방병원 2000 惠和醫學 Vol.9 No.2

This experimental study was carried out to evaluate the effects of Cordiceps sinensis on the antimetastasis and immune activity. In order to investigate the effect of Cordiceps sinensis, the followings were performed; Cytotoxicity, inhibition of MMP-2 & MMP-9 gene expression, fraction of CD4+, CD8+, CD19+ in splenic cell, the moprphological change of splenic cells, gene expression of IL-12(p35), IL-12(p40), IFN-?? and splenic cell proliferation by CS-E. The results were obtained as follows. 1. CS-E did not present cytotoxic effect on L+14, B16-F10 melanoma cells and HMCB. 2. CS-E inhibited MMP-2 and MMP-9 gene expression more effectively compared with control group. 3. CS-E inhibited invasion of B16-F10 melanoma cells more effectively compared with control group. 4. CS-E helped CD4+, CD8+, CD19+ expression more effectively compared with control group. 5. CS-E activated phagocytic cells in spleen more effectively compared with control group. 6. CS-E helped IL-12(p35), IL-12(p40), IFN-?? gene expression in splenic cell more effectively compared with control group. 7. CS-E activated splenic cell proliferation more effectively compared with control group. From above findings, it is suggested that CS-E is able to inhibit metastasis of cancer and activate immune response system.

腸內棲息菌에 對한 硏究 : 變形菌(Proteus)에 關한 硏究

石鐘聲,金漢壽,張友鉉,李承薰 現代醫學社 1969 現代醫學 Vol.10 No.2

The proteus group are known to be widely distributed in nature and also constitute one of the important micro-flora, of human intestines. The identification of the Proteus and further differentiation into 5 species are made chiefly by their biochemical activities, which are conventionally studied with the cultures grown at 37℃. Since it is known that the metabolic activities of bacteria are influenced by the physicochemical natures of environment, it is conceivable that results of bacterial identification and differentiation based on their biochemical reactions might be different when the culture conditions differ. Thus, 100 strains of the proteus isolated from various clinical specimens were grown aerobically at 37℃ and 22℃ and the patterns of their 1, biochemical activities under the different cultural conditions were studied. The results might be summarized as follows: 1) By the biochemical activities with the cultures grown at 37℃, 100 proteus strains were differentiated into 4 species; P. rettgeri 4, P. vulgaris 14, P. mirabilis 36, and P. morganii 46. 2) If the differentiation into the species was made by the biochemical activities with the cultures grown at 22℃, the 100 strains might be classified into, P. rettgeri 41, P. vulgaris 20, P. mirabilis 34, and P. morganii 5. 3) Regardless the difference of the culture temperatures, 47 strains among the 100 strains were identified into the same species of proteus; P. rettgeri 2, P. vulgaris 7, P. mirabilis 33, and P. morganii 5. 4) Biochemically the proteus strains appeared to be more active at 37℃ than at 22℃. 5) The distribution of the 100 strains among the clinical specimens were stool or recta swat 68, pus or discharge 14, urine 10 and miscelleneous specimen 8.

구륜이동로봇의 모델링과 Time-Scaling 기법을 이용한 경로추적

문종우,김종수,박세승 조선대학교 전자정보통신연구소 2003 電子情報通信硏究所論文誌 Vol.6 No.1

In this paper are presented kinematic and dynamic modeling and path-tracking of four-wheeled mobile robots with 2 d o f having the limited drive-torques Controllability of wheeled-mobile robots is revealed by using the kinematic model Instantaneously coincident coordinate cystem, force/torque propagation and Newton s equilibrium law are used to induce the dynamic model When drive-torques generated by inverse dynamics exceed the limitation, we make wheeled-mobile robots follow the reference path by modifying the planned reference trajectory with time-scaling. The controller is introduced to compensate for error owing to modeling uncertainty and measurement noise. And simulation results prove that method proposed by this paper is efficient.

抗癌丹을 投與한 胃癌 患者 105例에 對한 臨床報告

유화승,최우진,이용연,서상훈,조정효,이연월,손창규,조종관 대전대학교 한방병원 2000 惠和醫學 Vol.9 No.2

Clinical studies were carried out 105 cases of patients with stomach cancer treated by Hangamdan(抗癌丹) from January 1th 1998 to September 30th 2000. The results were summarized as follows; 1. Distribution of those attached by stomach cancer, by sex, showed that Male is more then Female, by age, showed that the number of forties, fifties, sixties are majority. 2. Distribution of diagnostic stage, in descending order; stage Ⅲ(45.1%, top), stage Ⅳ(40.2%). 3. The effects of maintenance and improvement in the symptoms with traditional oriental therapy(77.8%) and combined treatment of western and oriental therapy(92.3%) were observed. The effects of the symptoms were as follows; abdominal pain (16.3%), general body weakness(10.5%), nausea&vomiting (8.6%), diarrhea(6.7%) and etc, in orders. 4. Analysis of hematology attached by stomach cancer, maintenance and increasing of WBC(89.4%), RBC(63.6%), Hgb(62.3%), Platelet(95.6%) were observed. After taken Hangamdan, the safety of the liver and kidney were as follows; maintenance and decreasing of AST(85.3%), ALT(91.6%), BUN(84.8%), Creatinine(92.4%) were observed. 5. Analysis of IL-12 and IFN-γ attached by stomach cancer, increasing of IL-12(39.1%), IFN-γ(69.6%) were observed. 6. Analysis of QOL attached by stomach cancer, maintenance and improvement of combined treatment of western and oriental therapy(91%), traditional oriental therapy(85.2%) were observed. 7. Analysis of survival in patients with Ⅳ stage of stomach cancer, above 6 months(17.1%), 12 months(85.2%) were observed. 8. Analysis of antitumor effects, maintenance of traditional oriental therapy(81.5%) and maintenance and improvement of combined treatment of western and oriental therapy(89.7%) were observed. Analysis of tumor marker attached by stomach cancer, maintenance of CEA(85.7%) were observed. 9. Analysis of curative valuation, maintenance and improvement of traditional oriental therapy(77.7%), combined treatment of western and oriental therapy(82.1%) were observed. From the above results, it is suggested that Hangamdan has significant effects of antitumor and immune activity, also could be usefully applied for stomach cancer patients by combination with western therapy or alone.

西歐 代替醫學의 癌 治療에 關한 硏究

兪和承,李容淵,徐祥熏,崔宇鎭,曺政孝,李淵月,孫彰奎,趙鍾寬 대한한방종양학회 2000 대한한방종양학회지 Vol.6 No.1

At here, we investigated the historical background, current stage, and concrete therapies of altematives in cancer therapy. We obatined the conclusion below. 1. Alternative medicine(AM) is a unothodoxial medical physiology, medical practice or intervension that overcome the side effects. faults, limits of coventional medicine. 2. Recentely, as emerging New-age movement, collgpse of Decarte's mecanical cosmology, and emphasis on patient rights, the interest of AM is increased, and foreign & domestic use rates of AM are risen. 3. After coventional medicine in cancer therapies tha depends on poerations, radiations, and chemotherapy is bounded, Altematives in cancer therapy are rapidly developed, and the majority of users are often considered satisfactory. 4. Alternatives in cancer therapy are classified six boundaries; Diet and Nutrition, MInd-body Technique, Integrated System, Pharmacologic and Biologictreatments, Immuno Enhanced Therapy, Immuno Enthaced Therapy, Natural and herbal medicine. 5. Looking at contents of Alternatives in cancer therapy, we get to know most of them are similar to the treatment of oriental medicine in holistic method, therapy, philosophy. If we synthesize the alternative medicine's treatment mentioned above and investigate it with oriental medical viewpoint, that may help us approach the conquest of cancer and improve the rate of cure. that may help us approach the conquest of cancer and improve the rate of cure. 6. It is certain that foreign AM will be imported reversely, and we must prepare for rebuilding of Korean traditional AM systemically, investing for activity positively, making national policy for medical system.

FeCoB계 아몰퍼스 자성박막의 임피던스효과에 관한 연구

서강수,정승우,임재근,신용진 명지대학교 대학원 1997 대학원논문집 Vol.1 No.-

In this paper, we has studied frequency dependence of impedance of FeCoB amorphous magnetic films. First, we investigated optimal composition and sputtering conditions for fabrication of zero magnetostrictive amorphous magnetic films. (Fe_(1-x)Co_x)_79Si_2B_19 was selected as the basic composition and then, the films were fabricated with x=0.94 and 0.95 respectively by using sputtering method at high frequency. In order to relieve the internal pressure and derive the magneto-anisotropic. we annealed the films in about 150[Oe] of magnetic field and in the range(280℃, 300℃ and 320℃ respectively) of crystallization temperature(360℃). In addition, we annealed the films under non-magnetic field and near crystallization temperatures (283℃/30min, 400℃/30min and 400℃/1hr respectively) in order to decrease magnetoanisotropic. Then, we investigated magnetic properties including magneto-impedence and inductance. As the results, we found excellent magnetic characteristics and high impedence changing rate(4.52[%/Oe]) when we fabricated a sample under the condition that input power 400[W], Ar gas pressure 6.4[mTorr]. sputtering time 30[min] and annealing time 30[min] at 300[℃] in 150[Oe] magnetic field Especially, the impedence changing rate which was basic characteristic of Ml element was 4.52[%/Oe] for x=0.94. Moreover, the inductance values of the samples annealed at 400[℃/30min] were higher by 132[%] to 197[%] than those of the non-annealed samples. In addition, the quality factor Q was below 0.7 for all samples. Consequently, we find that the zero magnetostrictive amorphous magnetic film can be used as a magnetic sensor material.

심장수술 시 농축적혈구, 자가수혈기 혈액, 체외 순환기 혈액에서의 유리 혈색소 농도 비교

송장호,구승우,백종화,정용보,이정순,최인철 대한마취과학회 2002 Korean Journal of Anesthesiology Vol.43 No.5

Background: Intraoperative autotransfusion or residual blood in a cardiopulmonaty bypass (CPB) circuit has been used to reduce the need for an homologous blood transfutsion during cardiac surgery. However, it may contain some free hemoglobin released from damaged cells. The load of blood containing free hemoglobin may cause renal dysfunction. We measured the amount of free hemoglobin in backed blood, cell saver blood and CPB blood to evaluate what is the least hemolytic blood transfused in cardiac surgery. Methods: This study was performed in 20 patients undergoing cardiac surgery. In each patient, the banked blood, intraoperative salvaged blood with a cell saver and CPB residual blood were sampled at the end of the operation. The concentration of free hemoglobin, hemoglobin and platelet counts were measured in these blood samples and percent of hemolysis was calculated (%hemolysis = [free hemoglobin] / .free hemogloben + hemoglobin]) Results: In salvaged blood with a cell saver, CPB residual blood and banked blood, hemoglobin concentrations were 20.1 ± 2.7 g/dl, 8.0 ± 1.1 g/dl, and 22.2 ± 2.7 g/dl, respectively. Free hemoglobin concentrations were 336.6 ± 239.5 mg/dl, 49.2 ± 26.8 mg/dl, and 279.5 ± 167.5 mg/dl respectively. Platelet counts were 26.1 ± 22.2 × 10^3/mm^3, 116.8 ± 56.5 × 10^3/mm^3, and 94.9 ± 43.6 × 10^3/mm^3 respectively. % Hemolysis were 1.6 ± 1.1%, 0.6 ± 0.4%, and 1.2 ± 0.7% respectively. In the comparison between the salvaged blood with a cell saver and CPB residual blood, free hemoglobin concentration, % hemolysis, and platelet counts had positive correlations (r = 0.8, 0.7, and 0.6). Conclusions: In twenty cardiac surgeries, CPB residual blood had a lower free hemoglobin level than the other two blood groups. The platelet counts in CPB residual blood were higher than those in cell saver blood but did not differ from those in banked blood. Therefore, CPB residual blood was the least hemolytic blood among the three blood groups when a transfusion was performed in cardiac surgery. (Korean J Acesthesiol 2002; 43: 588~593)

急性 骨髓性 白血病 患者 1例에 對한 臨床報告

조정효,유화승,최우진,이용연,서상훈,이연월,손창규,조종관 대전대학교 한방병원 2000 惠和醫學 Vol.9 No.2

AML is the most common type of leukemia in adults. AML(acute myeloid leukaemia) is characterised by a rapid accumulation of abnormal white blood cells in the blood and bone marrow, resulting in severe anemia, and possibly infection, and hemorrhage during the course of the disease. In general the prognosis of patient with relapsed AML is poor. At this time, however, the only potentially curative therapy for relapsed patients is allogeneic BMT(bone marrow transplantation). This clinical study were carried out 1 case of female patient aged 44 with relapsed AML treated by herb medicine. At the time of admission, she complained of mild fever, nausea, vomitting, abdominal pain, anorexia and no sign of bleeding. For the 10 days of admission, she was treated with Oriental-Western medicine and all the symptoms were disappeared. After that, the syptoms were aggravated because of secondary infection. Anyway, above result showed the possibility of Oriental therapy as Supportive Care in AML.