Implementation of UPT Service in WIN-Based Mobile Communication Networks

Yun Won Chung(정윤원),Min Young Chung(정민영),Dan Keun Sung(성단근),In Jeong Kim(김인정),Jung Keun Shin(신정근),Sung Kim(김성) 한국통신학회 1999 한국통신학회 학술대회 및 강연회 Vol.1999 No.4

시베리아내전의 발발과 연해주 한인사회의 동향

윤상원(Yun Sang-won) 고려사학회 2010 한국사학보 Vol.- No.41

The aim of this article is to clarify the origin of the Korean armed struggle in Chien tao and Russian Far East in the early 1920s. In conclusion, I believe that the origin of Korean armed struggle is the Russian Revolution in 1917 and ensuing civil war in Siberia. In particular, Japanese forces in Siberia after the Russian Revolution made Koreans in that region to struggle with Soviet Red Army and Russian partisan troops. Japan has sent troops to Siberia in 1918 and supported White army in Russian civil war. For this reason Koreans naturally jumped into the fight against the Japanese and the Whites. And the armed struggle taken place in Siberia soon had an impact on the Korean community in Chientao. Korean patriots in Chien tao also began a battle with the Japanese. From this wide range of armed struggle has unfolded in Chientao and Russian Far East in the early 1920s. But the Koreans partisan movement in Russia also had to be affected to the presence and movements of Koreans in that Region in the previous time. Korean community in Russia also had a class problem. Some of Koreans who early imigrated to the Russian territory and acquired Russian nationality, received land distribution from the Russian government and were incorporated into the ruling class. They were called 'Won-he-in'. In contrast, there were Koreans who were not acquired Russian nationality. As there was no land for them, They had cultivated the land of Russian landlord or Won-ho-in. otherwise, became the daily agricultural workers. They were "Yo-ho-in". And of course, Won-he-in were the side of White army and Red army had the support of Yo-ho-in.

Growth Inhibition of Colon Cancer through Inactivation of STAT3 Pathway by IL-10 and IL-1ra Released from Murine Macrophage

Jin Tae Hong, Dohee Won1, Mi Hee Park, Sun Mi Kown, Miran Jo, Sang-Yoon Nam, Beom Jun Lee, Young Won Yun, Ki-Wan Oh, Sang Bae Han 충북대학교 동물의학연구소 2011 Journal of Biomedical and Translational Research Vol.12 No.4

The objective of this study was to determine the effect of macrophages on growth of human colon cancer cells. The results showed that co-culture of colon cancer cells with macrophages inhibited the growth of colon cancer cells (HCT116 and SW620) depending on the number of macrophages, RAW 264.7 cells, and activated THP-1 cells accompanied by down regulation of pSTAT3 in cancer cells. We also found that expression and release of cancer cell growth inhibitory cytokines, IL-1 receptor antagonist (IL-1ra) and IL-10, was increased in macrophages. Blocking of the STAT3 pathway with specific inhibitor and siRNA of STAT3 abolished the growth of colon cancer cells and expression of IL-1ra and IL-10. In addition, neutralization of IL-1ra and IL-10 with antibodies resulted in reversal of macrophage-induced inhibition of cancer cell growth. These data showed that IL-1ra and IL-10 released from macrophages inhibit growth of colon cancer cells through inhibition of the STAT3 pathway

오공약침의 안전성에 대한 임상적 연구

소기숙,최회강,박소영,고강훈,김성남,이옥자,윤민영,문형철,김성철,이정훈,나원경,So, Ki-suk,Choi, Hoi-kang,Park, So-young,Koh, Kang-hun,Kim, Sung-nam,Lee, Ok-ja,Yun, Min-young,Mun, Hyung-chul,Kim, Sung-chul,Lee, Jung-hun,Na, Won-kyung 대한침구의학회 2004 대한침구의학회지 Vol.21 No.1

Objective: Recently scolopendrid aquacupuncture has been a good effect on pain control but it has not been known about clinical safety. So, In order to prove the clinical safety of scolopendrid aquacupuncture, We have observed the physical reac-tion and clinical pathology test after scolopendrid aquacupuncture treatment. Methods: We analyzed physical reaction and clinical pathology test before and after Scolopendrid aquacupuncture treatment of 30 patients suffering from pain, who admitted department of Acupunture and Moxibustion, College of Oriental Medicine, Won-Kwang University Kwangju hospital. Results & Conclusions: The results were summarized as follows. 1) The distribution of sex was 14 males and 16 females, and the average of patients age was 46.2 years. 2) The distribution of symptom was lumbago, lumbago with radiating pain, nuchal pain and knee joint pain. 3) In the 30 patients treated with Scolopendrid aquacupuncture, hematologic test did not show remarkable change. 4) In the 30 patients treated with Scolopendrid aquacupuncture, Liver function test(AST, ALT, ALP) showed a slight decrease on the contrary, and abnormal rate showed a decrease of 1.0%(from 3.3% to 2.3%) compared with previous study. 5) In the 30 patients treated with Scolopendrid aquacupuncture, Renal function test(BUN, Cr) and abnormal rate(from 2.5% to 2.0%) showed a slight decrease on the contrary. 6) In the 30 patients treated with Scolopendrid aquacupuncture. Electrolyte were normal range before & after treatment. 7) In the results of the Urine analysis of 30 patients, Leukocyte, Protein. Glucose, Keton, Bilirubin, U-bilinogen were not detected before and after Scolopendrid aquacupuncture treatment, and the rest almost made no difference. 8) In the Physical reactions, all of the patients complained of pain of body partially, only one patient showed reddish and itch, but symptoms like those were entirely disappeared within 24 hours and whole body pain, swelling, headache, dizziness, fatigue and nausea was not observed.

자동착유시스템 설치농가의 설치 후 만족도에 관한 실태조사

기광석,김종형,정영훈,김윤호,박성재,김상범,이왕식,이현준,조원모,백광수,김현섭,권응기,김완영,여준모,Ki, Kwang-Seok,Kim, Jong-Hyeong,Jeong, Young-Hun,Kim, Yun-Ho,Park, Sung-Jai,Kim, Sang-Bum,Lee, Wang-Shik,Lee, Hyun-June,Cho, Won-Mo,Baek, Kwang- 한국축산환경학회 2011 축산시설환경학회지 Vol.17 No.1

본 시험은 국내에 도입되기 시작한 AMS에 대하여 설치 동기, 설치 후 우유생산량과우유품질, AMS 설치계기 및 설치 후 만족도, AMS 운영상 애로점 및 건의사항 등을 조사 분석하였다. 설치 계기가 무엇인가에 대한 응답비율은 노동력 부족 44%, 체험목장으로 전환 25%, 소들의 고능력화에 대응 19% 순이었으며 기타 6%였다. AMS 설치농가의 사육경력은 평균 24.9년, 평균 연령은 53.2세로 나타났으며 가족노동력만으로 경영하는 목장이 조사농가의 38%, 고용+자가노동력 형태의 목장이 63%로 나타났다. 목장의 산유능력은 두당 평균 유량은 1일 $30.9{\ell}$, 평균 유지율 3.9%, 세균수는 9.1천개/$m{\ell}$ 수준이었다. 후계자 육성에 대한 질문에 매우 그렇다라고 응답한 비율은 68%였으며, 보통 18%, 아니다와 매우 아니다라고 응답한 비율은 18%로 나타났다. 시스템 운영현황 및 애로사항을 파악하기 위하여 AMS의 프로그램 주운영자에 대한 질문에 본인 44%, 부인 6%, 자녀 또는 후계자사람이 44%, 기타 6%나 되었다. AMS 운영상 가장 어려운 점에 대한 조사결과, 기기 작동 및 복잡한 프로그램 운영이 각각 31%로 가장 많았다. 그 외 기계 에러 및 고장에 대한 애로사항이 25%이였다. 도태원인에 대하여 유방염 28%, 번식장애 20%, 발굽질환 19%, AMS에 부적합한 유두 배열 12%, 분만 후 대사성질병 7%, 노산 등 기타 14%였다. 시스템 설치 후 유지보수 계약 체결유무 및 비용에 대하여 유지보수 계약 56%, 유지 보수 계약 미체결 44%이었다. 유지보수 계약 평균 계약비용은 연간 658만원 정도였다. 시스템 설치 후 항목별 만족도에 대하여 5점 만점에 3.9점이었으며, 노동력 절감 3.7점, 업체의 A/S 3.6점, 산유량 증가 3.2점, 원유의 체세포 수 저감 2.8점이었다. 시스템 설치 시 고려사항 및 건의사항에 대하여 고가의 장비를 효율적으로 사용하기 위하여 젖소의 유방과 유두 배열이 적합하도록 젖소를 선발하는 것, 시스템을 운용할 수 있는 능력, 적합한 환경, 재정적 능력과 부지 확보, 지속적인 관찰 등이 권장되어야 할 것으로 나타났으며, 설치 업체에 대해서는 컨설팅이 체계화될 필요가 가장 높게 나타났으며 이어서 보다 저렴한 설치와 서비스의 체계화를 요구하는 결과를 보였다. The present survey was conducted to provide basic information on automatic milking system (AMS) in relation to purchase motive, milk yield and quality, customer satisfaction, difficulties of operation and customer suggestions, etc. Purchase motives of AMS were insufficient labor (44%), planning of dairy experience farm (25%), better performance of high yield cows (19%) and others (6%), respectively. Average cow performance after using AMS was 30.9l/d for milk yield, 3.9% for milk fat, 9,100/ml for bacterial counts. Sixty-eight percentage of respondents were very positive in response to AMS use for their successors but 18% were negative. The AMS operators were owner (44%), successor (44%), wife (6%) and company worker (6%), respectively. The most difficulty (31%) in using AMS was operating the system and complicated program manual. The rate of response to system error and breakdown was 25%. The reasons for culling cow after using AMS were mastitis (28%), reproduction failure (19%), incorrect teat placement (12%), metabolic disease (7%) and others (14%), respectively. Fifty-six percentages of the respondents made AMS maintenance contract and 44% did not. Average annual cost of the maintenance contract was 6,580,000 won. Average score for AMS satisfaction measurement (1 to 5 range) was 3.2 with decrease of labor cost 3.7, company A/S 3.6, increase of milk yield 3.2 and decrease of somatic cell count 2.8, respectively. Suggestions for the higher efficiency in using AMS were selecting cows with correct udder shape and teat placement, proper environment, capital and land, and attitude for continuous observation. Systematic consulting was highly required for AMS companies followed by low cost for AMS setup and systematization of A/S.

Role of hypoxia-mediated cellular prion protein functional change in stem cells and potential application in angiogenesis

Yun, Seung Pil,Han, Yong-Seok,Lee, Jun Hee,Yoon, Yeo Min,Yun, Chul Won,Rhee, Peter,Lee, Sang Hun SPANDIDOS PUBLICATIONS 2017 MOLECULAR MEDICINE REPORTS Vol.16 No.5

<P>Cellular prion protein (PrP<SUP>C</SUP>) can replace other pivotal molecules due to its interaction with several partners in performing a variety of important biological functions that may differ between embryonic and mature stem cells. Recent studies have revealed major advances in elucidating the putative role of PrP<SUP>C</SUP> in the regulation of stem cells and its application in stem cell therapy. What is special about PrP<SUP>C</SUP> is that its expression may be regulated by hypoxia-inducible factor (HIF)-1α, which is the transcriptional factor of cellular response to hypoxia. Hypoxic conditions have been known to drive cellular responses that can enhance cell survival, differentiation and angiogenesis through adaptive processes. Our group recently reported hypoxia-enhanced vascular repair of endothelial colony-forming cells on ischemic injury. Hypoxia-induced AKT/signal transducer and activator of transcription 3 phosphorylation eventually increases neovasculogenesis. In stem cell biology, hypoxia promotes the expression of growth factors. According to other studies, aspects of tissue regeneration and cell function are influenced by hypoxia, which serves an essential role in stem cell HIF-1α signaling. All these data suggest the possibility that hypoxia-mediated PrP<SUP>C</SUP> serves an important role in angiogenesis. Therefore, the present review summarizes the characteristics of PrP<SUP>C</SUP>, which is produced by HIF-1α in hypoxia, as it relates to angiogenesis.</P>

Clinicopathological Characteristics of Colon Cancer Diagnosed at Primary Health Care Institutions

( Sang Hyun Park ),( Chi Wook Song ),( Yun Bae Kim ),( Young Sun Kim ),( Hwang Rae Chun ),( Jung Hyun Lee ),( Won Jong Seol ),( Hyung Sun Yoon ),( Myung Kwon Lee ),( Jong Hyup Lee ),( Choon Sang Bhang 대한장연구학회 2014 Intestinal Research Vol.12 No.2

Background/Aims: The purpose of this study was to evaluate the clinicopathologic characteristics of colon cancers detectedat the SOK Sokpeynhan Internal Medical Network, a nationwide system of primary health care institutions. Methods: Weanalyzed 579 colon cancer patients diagnosed using colonoscopy at the SOK network from January 2011 through December2012. Cancers from the rectum to the splenic flexure were classified as left colon cancer. Patients over 65 were classified assenior. Results: The mean age (±SD) of subjects was 60.9±10.5 years and 61.1% were men. More than one quarter (28.2%) ofpatients were asymptomatic. The prevalence of left colon cancer was higher (77.9%) than that for right colon cancer. The mostfrequent macroscopic and histologic types were depressed (58.9%) and moderately differentiated adenocarcinoma (52.2%),respectively. Asymptomatic subjects displayed protruding or well differentiated adenocarcinoma, while symptomatic patientswere more likely to display depressed or moderately differentiated adenocarcinoma (P <0.05). The mean age of the right coloncancer group was higher than that for the left colon cancer group (P <0.05). Among symptomatic patients, the most frequentsymptoms were bloody stool for patients with left colon cancer and abdominal discomfort for patients with right colon cancer(P <0.05). The prevalence of depressed cancer was higher in older subjects as compared to younger subjects (P <0.05). Theprevalence of right colon cancer tended to increase with age, although this difference did not achieve statistical significance(P >0.05). Conclusions: Study results indicated an increase of colon cancer amongst younger demographics in recent years.The effectiveness of colonoscopy screening was also evident, as asymptomatic patients demonstrated frequent findings of welldifferentiated adenocarcinomas. Study results also suggested a need for closer examination of older patients, as right coloncancer tended to increase with age. (Intest Res 2014;12:131-138)

Design of Dual-Band Bandpass Filters for Cognitive Radio Application of TVWS Band

Sang-Won Yun,Hyun-Keun Kim,Kun-An Kwon 한국전자파학회JEES 2016 Journal of Electromagnetic Engineering and Science Vol.16 No.1

This paper presents a novel design for dual-band bandpass filters. The proposed filters are applicable to the carrier aggregation of the TV white space (TVWS) band and long-term evolution (LTE) band for cognitive radio applications. The lower passband is the TVWS band (470–698 MHz) whose fractional bandwidth is 40 %, while the higher passband is the LTE band (824–894 MHz) with 8 % fractional bandwidth. Since the two passbands are located very close to each other, a transmission zero is inserted to enhance the rejection level between the two passbands. The TVWS band filter is designed using magnetic coupling to obtain a wide bandwidth, and the LTE band filter is designed using dielectric resonators to achieve good insertion loss characteristics. In addition, in the proposed design, a transmission zero is placed with cross-coupling. The proposed dual-band bandpass filter is designed as a two-port filter (one input/one output) as well as a three-port filter (one common input/two outputs). The measured performances show good agreement with the simulated performances.

Multi-omics Based Analysis for Investigation of Roseburia intestinalis as a Promising Butyrate-Producing Probiotic in Human Intestinal Epithelial Cells

Won-Suk SONG,Seo-Young KWON,Sung-Hyun JO,Ye-Rim KIM,Ji-Hyun BAEK,Min-Gyu KIM,Ju-Yeon HAN,Yun-Gon KIM 한국생물공학회 2023 한국생물공학회 학술대회 Vol.2023 No.4

QTL Mapping of Grain Quality Traits Using Introgression Lines Carrying <i>Oryza</i> <i> rufipogon</i> Chromosome Segments in <i>Japonica</i> Rice

Yun, Yeo-Tae,Chung, Chong-Tae,Lee, Young-Ju,Na, Han-Jung,Lee, Jae-Chul,Lee, Sun-Gye,Lee, Kwang-Won,Yoon, Young-Hwan,Kang, Ju-Won,Lee, Hyun-Sook,Lee, Jong-Yeol,Ahn, Sang-Nag Springer US 2016 Rice Vol.9 No.-

<P><B>Background</B></P><P>Improved eating quality is a major breeding target in <I>japonica</I> rice due to market demand. Consequently, quantitative trait loci (QTL) for glossiness of cooked rice and amylose content associated with eating quality have received much research focus because of their importance in rice quality.</P><P><B>Results</B></P><P>In this study, QTL associated with 12 grain quality traits were identified using 96 introgression lines (IL) of rice developed from an interspecific cross between the Korean elite <I>O. sativa japonica</I> cultivar ‘Hwaseong’ and <I>O. rufipogon</I> over 7 years. QTL analyses indicated that QTL <I>qDTH6</I> for heading date, detected on chromosome 6 is associated with variance in grain traits. Most QTLs detected in this study clustered near the <I>qDTH6</I> locus on chromosome 6, suggesting the effect of <I>qDTH6. O. rufipogon</I> alleles negatively affected grain quality traits except for a few QTLs, including <I>qGCR9</I> for glossiness of cooked rice on chromosome 9. To characterize the effect of the <I>O. rufipogon</I> locus harboring <I>qGCR9,</I> four lines with a single but different <I>O. rufipogon</I> segment near <I>qGCR9</I> were compared to Hwaseong. Three lines (<I>O. rufipopgon</I> ILs) having <I>O. rufipogon</I> segment between RM242 and RM245 in common showed higher glossiness of cooked rice than Hwaseong and the other line (Hwaseong IL), indicating that <I>qGCR9</I> is located in the 3.4-Mb region between RM242 and RM245. Higher glossiness of cooked rice conferred by the <I>O. rufipogon</I> allele might be associated with protein content considering that three lines had lower protein content than Hwaseong (<I>P</I> < 0.1). These three <I>O. rufipogon</I> ILs showed higher yield than Hwaseong and Hwaseong IL due to increase in spikelets per panicle and grain weight indicating the linkage of <I>qGCR9</I> and yield component QTLs.</P><P><B>Conclusion</B></P><P>The <I>qGCR9</I> locus is of particular interest because of its independence from other undesirable grain quality traits in <I>O. rufipogon</I>. SSR markers linked to <I>qGCR9</I> can be used to develop high-quality <I>japonica</I> lines and offer a starting point for map-based cloning of genes underlying this trait. To our knowledge, this is the first report to map a beneficial QTL for glossiness of cooked rice from a wild rice, <I>O. rufipogon</I>.</P><P><B>Electronic supplementary material</B></P><P>The online version of this article (doi:10.1186/s12284-016-0135-0) contains supplementary material, which is available to authorized users.</P>