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RISS 인기검색어
- 검색키워드
- 저자 : Runa Masuma (검색결과 3 건)
- 무료
- 기관 내 무료
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Pharmacological findings of an Indian traditional Ayurvedic herbalformulation Amritaristo
Masuma, Runa,Choudhuri, MSK,Rajia, Sultana,Alamgir, Mahiuddin Kyung Hee Oriental Medicine Research Center 2008 Oriental pharmacy and experimental medicine Vol.8 No.3
In this present study Indian traditional Ayurvedic herbal formulation Amritaristo has been studied to assess the general pharmacological effect on mice. The drug showed no significant activity on the neuropharmacological test models experimented. The increased pentobarbital sleeping time was considered related with hepatic metabolism of pentobarbital. The formulation exhibited a non-significant reduction of gastrointestinal motility, and devoid of any acute diuretic activity. The tested drug revealed antidiarrhoeal activity on castor oil-induced model, whereas on magnesium sulphate-induced model no effect was observed.
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Pharmacological findings of an Indian traditional Ayurvedic herbal formulation Amritaristo
Runa Masuma,MSK Choudhuri,Sultana Rajia,Mahiuddin Alamgir 경희대학교 융합한의과학연구소 2008 Oriental Pharmacy and Experimental Medicine Vol.8 No.3
In this present study Indian traditional Ayurvedic herbal formulation Amritaristo has been studied to assess the general pharmacological effect on mice. The drug showed no significant activity on the neuropharmacological test models experimented. The increased pentobarbital sleeping time was considered related with hepatic metabolism of pentobarbital. The formulation exhibited a nonsignificant reduction of gastrointestinal motility, and devoid of any acute diuretic activity. The tested drug revealed antidiarrhoeal activity on castor oil-induced model, whereas on magnesium sulphate-induced model no effect was observed. In this present study Indian traditional Ayurvedic herbal formulation Amritaristo has been studied to assess the general pharmacological effect on mice. The drug showed no significant activity on the neuropharmacological test models experimented. The increased pentobarbital sleeping time was considered related with hepatic metabolism of pentobarbital. The formulation exhibited a nonsignificant reduction of gastrointestinal motility, and devoid of any acute diuretic activity. The tested drug revealed antidiarrhoeal activity on castor oil-induced model, whereas on magnesium sulphate-induced model no effect was observed.
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Md. Al Foyjul Islam,Anindya Barua,Maksud Hassan Binoy,Md. Jahir Alam,Md. Ershad,M. S. K. Choudhuri,Runa Masuma 경희대학교 융합한의과학연구소 2019 Oriental Pharmacy and Experimental Medicine Vol.19 No.4
Wedelia trilobata (WT) has been used in folk medicine to alleviate several diseases such as cough, cold, fu, fever and infammation. The study was investigated to evaluate anti-diarrheal and CNS efect of ethanolic extract of W. trilobata in mice. Anti-diarrheal efect was evaluated using castor oil and MgSO4 induced diarrhea tests in mice. Gastrointestinal motility was measured using BaSO4. CNS efect was investigated using hole board, hole cross and elevated plus maze tests. Extract was used at dose of 1000 mg/kg and 2000 mg/kg body weight. Loperamide (10 mg/kg per oral) and diazepam (4 mg/kg) were used as standard drug. The crude extract exhibited signifcant anti-diarrheal efect in the total number of feces and episodes of diarrheal feces. Treatment with WT at both the doses, very highly reduced diarrhea signifcantly (p<0.001) in castor oil and MgSO4 induced diarrheal tests. WT at 1000 mg/kg and 2000 mg/kg reduced diarrheal stools by 71.25% (p<0.001) and 76.25% (p<0.001) in castor oil induced diarrhea. In the MgSO4 induced diarrhea, the extract reduced diarrhea by 62.79% (p<0.001) and 65.12% (p<0.001), respectively. WT at 2000 mg/kg inhibited GI motility very highly signifcantly (p<0.001). Standard drug, loperamide (10 mg/kg) had very highly signifcant (p<0.001) antidiarrheal efect. In the CNS, the extract resulted signifcant depressant efect (p<0.001) in hole board, hole cross and elevated plus maze test. WT extract possessed signifcant antidiarrheal and CNS depressant properties.
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