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        Methods for evaluating effects of unloader knee braces on joint health: a review

        Rizuwana Parween,Duraisamy Shriram,Rajesh Elara Mohan,Yee Han Dave Lee,Karupppasamy Subburaj 대한의용생체공학회 2019 Biomedical Engineering Letters (BMEL) Vol.9 No.2

        The paper aims to provide a state-of-the-art review of methods for evaluating the eff ectiveness and eff ect of unloaderknee braces on the knee joint and discuss their limitations and future directions. Unloader braces are prescribed as a nonpharmacologicalconservative treatment option for patients with medial knee osteoarthritis to provide relief in terms of painreduction, returning to regular physical activities, and enhancing the quality of life. Methods used to evaluate and monitorthe eff ectiveness of these devices on patients’ health are categorized into three broad categories (perception-, biochemical-,and morphology-based), depending upon the process and tools used. The main focus of these methods is on the short-termclinical outcome (pain or unloading effi ciency). There is a signifi cant technical, research, and clinical literature gap in understandingthe short- and long-term consequences of these braces on the tissues in the knee joint, including the cartilage andligaments. Future research directions may complement existing methods with advanced quantitative imaging (morphological,biochemical, and molecular) and numerical simulation are discussed as they off er potential in assessing long-term andpost-bracing eff ects on the knee joint.

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