http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : Rai V. Ravishankar (검색결과 1 건)
- 무료
- 기관 내 무료
- 유료
-
Selenium nanostructure: Progress towards green synthesis and functionalization for biomedicine
Ranjitha V. R.,Rai V. Ravishankar 한국약제학회 2021 Journal of Pharmaceutical Investigation Vol.51 No.2
Background Selenium is a pivotal micronutrient required for the proper functioning of the body. Deficiency of Se leads to various diseases whereas a high dosage of Se possesses toxicity. To reduce the toxic effects of elemental selenium and to maximize its efficacy, synthesis of selenium at the nanoscale level is important. Selenium nanoparticles (SeNPs) have received considerable attention in the past few decades. Synthesis of nano selenium with unique properties is necessary for its biomedical applications. Synthesis steps involve physical, chemical and biological methods. The biological or green synthesis method is often more advantageous than other available methods because of the major drawbacks involved in those methods. Area covered SeNPs synthesised through green route, such as microbes and plants, are summarized in this review. Synthesised SeNPs that is functionalized with different biological moieties are discussed and listed. Green synthesis involves the use of eco-friendly plants and microbes as the route for the synthesis. SeNPs are non-toxic and stable due to the natural capping agent that prevents protein aggregation and maintains the stability of the nanoparticles. Expert opinion To achieve targeted drug delivery of the synthesized nanomaterials and to increase the efficacy of the SeNPs with minimal toxicity, functionalization is an essential tool in the field of nanomedicine. Functionalized SeNPs with various biological moieties offer enhanced cytotoxicity against various cancer cell lines, good stability and targeted drug delivery without non-specific interaction compared to nanoparticle alone. The present review focuses on detailed report and progress towards the green approach for SeNPs synthesis and engineering selenium nanomaterials with different moieties possibly used for various biomedical applications.
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
