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Nosrat, Ali,Peimani, Ali,Asgary, Saeed The Korean Academy of Conservative Dentistry 2013 Restorative Dentistry & Endodontics Vol.38 No.4
Objectives: The purpose of the study was to evaluate human dental pulp response to pulpotomy with calcium hydroxide (CH), mineral trioxide aggregate (MTA), and calcium enriched mixture (CEM) cement. Materials and Methods: A total of nine erupted third molars were randomly assigned to each pulpotomy group. The same clinician performed full pulpotomies and coronal restorations. The patients were followed clinically for six months; the teeth were then extracted and prepared for histological assessments. The samples were blindly assessed by an independent observer for pulp vitality, pulp inflammation, and calcified bridge formation. Results: All patients were free of clinical signs/symptoms of pulpal/periradicular diseases during the follow up period. In CH group, one tooth had necrotic radicular pulp; other two teeth in this group had vital uninflamed pulps with complete dentinal bridge formation. In CEM cement and MTA groups all teeth had vital uninflamed radicular pulps. A complete dentinal bridge was formed beneath CEM cement and MTA in all roots. Odontoblast-like cells were present beneath CEM cement and MTA in all samples. Conclusions: This study revealed that CEM cement and MTA were reliable endodontic biomaterials in full pulpotomy treatment. In contrast, the human dental pulp response to CH might be unpredictable.
Ali Nosrat,Ali Peimani,Saeed Asgary 대한치과보존학회 2013 Restorative Dentistry & Endodontics Vol.38 No.4
Objectives: The purpose of the study was to evaluate human dental pulp response topulpotomy with calcium hydroxide (CH), mineral trioxide aggregate (MTA), and calciumenriched mixture (CEM) cement. Materials and Methods: A total of nine erupted thirdmolars were randomly assigned to each pulpotomy group. The same clinician performedfull pulpotomies and coronal restorations. The patients were followed clinically forsix months; the teeth were then extracted and prepared for histological assessments. The samples were blindly assessed by an independent observer for pulp vitality, pulpinflammation, and calcified bridge formation. Results: All patients were free of clinicalsigns/symptoms of pulpal/periradicular diseases during the follow up period. In CHgroup, one tooth had necrotic radicular pulp; other two teeth in this group had vitaluninflamed pulps with complete dentinal bridge formation. In CEM cement and MTAgroups all teeth had vital uninflamed radicular pulps. A complete dentinal bridgewas formed beneath CEM cement and MTA in all roots. Odontoblast-like cells werepresent beneath CEM cement and MTA in all samples. Conclusions: This study revealedthat CEM cement and MTA were reliable endodontic biomaterials in full pulpotomytreatment. In contrast, the human dental pulp response to CH might be unpredictable.