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      • SCOPUSKCI등재

        Vegetation change and emerging research feedback for Korean National Long Term Ecological Research (KNLTER)

        Cho, Yong-Chan,Lee, Chang-Seok,Cho, Hyun-Je,Lee, Kyu-Song,Park, Pil-Sun The Ecological Society of Korea 2011 Journal of Ecology and Environment Vol.34 No.1

        Various responses of forest ecosystems to climate change underscore the need to improve our understanding of the environmentally-driven changes in forests, most effectively by long-term monitoring protocols. We have explored vegetation dynamics based on changes in community structure, species composition, diversity and demographics in four Korean National Long Term Ecological Research (KNLTER) sites--Mt. Nam, Mt. Jeombong, Mt. Worak, and Mt. Jiri--between 2004 and 2009. Most of the sites and forests studied exhibited increments in total basal area, but this was not observed in Quercus mongolica forests in Mt. Nam and Mt. Worak. Stem density exhibited various changes. Altitude gradient was the representative factor in differences in species composition. Two patterns of compositional change--convergence and divergence--were detected. The vegetation of Mt. Nam and Q. mongolica community of Mt. Work showed relatively larger changes in composition. However, in the other sites, few changes were observed. Changes of species richness were not notable except for Mt. Nam, where three species were added in the pine forest, whereas one species disappeared in the oak forest. In the oak forests, mortality rate was as follows (in descending order): Mt. Nam (25.5%), Mt. Jeombong (24.3%), Mt. Worak (16.4%) and Mt. Jiri (0.8%). In the pine forest, the recruitment rate was as follows (in descending order): Mt. Nam (63.7%), Mt. Worak (12.9%), Mt. Jeombong (7.6%) and Mt. Jiri (7.3%). The mortality rate and change rate of basal area were strongly negatively correlated (r = -0.9, P = 0.002), and the recruitment rate and change rate of density were positively correlated (r = 0.77, P = 0.026). In the KNLTER sites, larger vegetation changes were attributed to anthropogenic activities such as salvage logging. Suppression or competition for resources would also affect these changes. Research suggestions such as monitoring to clarify the causes of species mortality were discussed.

      • AHCISCOPUSKCI등재
      • SCIEKCI등재

        Bone Marrow T Cells are Superior to Splenic T Cells to Induce Chimeric Conversion After Non-Myeloablative Bone Marrow Transplantation

        ( Hyun Sil Park ),( Seok Goo Cho ),( Min Jung Park ),( So Youn Min ),( Hong Seok Chang ),( Hee Je Kim ),( Seok Lee ),( Chang Ki Min ),( Jong Wook Lee ),( Woo Sung Min ),( Chun Choo Kim ),( Ho Youn Kim 대한내과학회 2009 The Korean Journal of Internal Medicine Vol.24 No.3

        Background/Aims: The bone marrow functions not only as the primary B-lymphocyte-producing organ but also as a secondary lymphoid organ for CD4 and CD8 cell responses and a site of preferential homing and persistence for memory T cells. Bone marrow T (BM-T) cells are distinguished from peripheral blood T cells by surface phenotype, cytokine secretion profile, and immune functions. In this study, we evaluated the alloreactive potential of donor lymphocyte infusion (DLI) using BM-T cells in mixed chimerism compared to that using spleen T (SP-T) cells. Methods: Cells were prepared using established procedures. BM-T cells were obtained as a by-product of T-cell depletion in BM grafting and then cryopreserved for subsequent DLI. We performed DLI using BM-T cells in allogeneic mixed chimera mice on post-BMT day 21. Results: When the same dose of T cells, 5-10×105 (Thy1.2+), fractionated from BM and spleen were administered into mixed chimeras, the BM-T group showed complete chimeric conversion, with self-limited graftversus-host disease (GVHD) and no pathological changes. However, the SP-T group showed persistent mixed chimerism, with pathological signs of GVHD in the liver and intestine. Conclusions: Our results suggest that DLI using BM-T cells, even in small numbers, is more potent at inducing chimeric conversion in mixed chimerism than DLI using SP-T cells. Further study is needed to determine whether cryopreserved BM-T cells are an effective cell source for DLI to consolidate donor-dominant chimerism in clinical practice without concerns about GVHD. (Korean J Intern Med 2009;24:252-262)

      • KCI등재

        30% 과산화수소를 함유한 전문가 미백제의 효용성 평가

        김신영,박재억,김창현,양성은 大韓齒科保存學會 2010 Restorative Dentistry & Endodontics Vol.35 No.1

        30% 과산화수소를 함유한 전문가 미백제인 레메화이트(Remewhite, Remedent Inc., Deurle, Belgium)를 시험군 피험자 31명, 시험용 미백제에서 과산화수소를 제외한 동일한 제재를 대조약으로 대조군 피험자 31명에게 1일 3회씩, 2차례에 걸쳐서 시행하였다. 미백의 임상적 효용성은 Colorimeter, Vitapan classical shade guide를 이용하여 전체 색변화량(□E*)을 측정하였다. 14주 후와 26주 후의 색변화량을 측정하여 군 간 색변화량을 비교하였고, 각 군 내에서의 색변화량도 비교하여 다음과 같은 결론을 얻었다. 1. Colohmeter를 이용한 평가시에 시험군에서 전체 색변화량(□E*)은 대조군에 비해 통계적으로 유의한 차이를 보였고, Vitapan classical shade guide를 이용한 평가시에는 통계적으로 유의한 차이를 나타내지 않았다(p < 0.05). 2. 시간이 지남에 따라 색 복원 현상이 나타남에도 불구하고 미백 시행 14주 후와 26주 후에도 미백의 효과가 유지된다고 할수 있다. 3. Colohmeter를 이용한 평가시에 Vitapan classical shade guide를 이용한 평가시보다 작은 색변화량을 더 정확하게 측정할 수 있다. This study evaluated the efficacy of an office bleaching gel (RemeWhite, Remedent Inc., Deurle, Belgium) containing 30% hydrogen peroxide. 31 volunteers were recieved office bleaching with the RemeWhite for 3 times at one visit, total 2 visits. As control group, the same gel in which hydrogen peroxide was not included was applied to 31 volunteers with the same protocol. The shade change (□E*, color difference) of 12 anterior teeth was measured using Colorimerter and Vitapan classical shade guide. The shade change of overall teeth in the experimental group was significantly greater than that in the control group which was measured using Colorimeter. There was also a significant difference between baseline and 14 weeks or 26 weeks though color rebounding phenomenon occurred as time went by. Small shade change difference can be measured accurately using Colorimeter than using Vitapan classical shade guide.

      • SCIESCOPUSKCI등재

        Combination of Vitamin C and Rutin on Neuropathy and Lung Damage of Diabetes Mellitus Rats

        Sohn, Uy-Dong,Je, Hyun-Dong,Shin, Chang-Yell,Park, Sun-Young,Yim, Sung-Hyuk,Kum, Chan,Huh, In-Hoi,Kim, Jin -Hak The Pharmaceutical Society of Korea 2002 Archives of Pharmacal Research Vol.25 No.2

        We investigated the role of vitamin C or rutin on neuropathy and lung damage of diabetic mellitus(DM) rats. Norepinephrine content was significantly decreased in sciatic nerves of DM rats compared with non-DM controls but vitamin C had no effect on decreases of norepinephrine. 2,4-dinitrophenylhydrazine (DNPH) incorporation, which is biomarker of protein oxidation, was increased in sciatic nerve of DM rats as compared with normal control. However, vitamin C had no effects on increases of DNPH incorporation . We measured the content of conjugated dienes (CD) as a biomarker of lipid oxidation in sciatic nerve. CD was increased in DM as compared with normal control, Vitamin C or rutin had no effects on increases of CD. However, Rutin plus vitamin C significantly decreased the content of CD as compared with CIM rats. In lung of DM rats, DNPH incorporation or CD was increased as compared with normal control. Vitamin C or Rutin had no effects on increases of CD However, Rutin plus vitamin C significantly decreased the content of DNPH incorporation or CD in lung tissue. Vitamin C caused marked pathological changes such as the increases of parenchyma and the thickening of alveolar septa in the lung of DM. Rutin had protective effects on the pathological changes in the lung of DM rats. In conclusion, Vitamin C had no effects on oxidative parameter, such as DNPH incorporation or CD, and on the decreases of norepinephrine content in DM rats. Vitamin C caused the marked pathological changes in the lung of DM rats but rutin had protective efforts against the pathological changes.

      • SCIESCOPUSKCI등재

        INVESTIGATION OF REACTOR CONDITION MONITORING AND SINGULARITY DETECTION VIA WAVELET TRANSFORM AND DE-NOISING

        Kim, Ok-Joo,Cho, Nan-Zin,Park, Chang-Je,Park, Moon-Ghu Korean Nuclear Society 2007 Nuclear Engineering and Technology Vol.39 No.3

        Wavelet theory was applied to detect a singularity in a reactor power signal. Compared to Fourier transform, wavelet transform has localization properties in space and frequency. Therefore, using wavelet transform after de-noising, singular points can easily be found. To test this theory, reactor power signals were generated using the HANARO(a Korean multi-purpose research reactor) dynamics model consisting of 39 nonlinear differential equations contaminated with Gaussian noise. Wavelet transform decomposition and de-noising procedures were applied to these signals. It was possible to detect singular events such as a sudden reactivity change and abrupt intrinsic property changes. Thus, this method could be profitably utilized in a real-time system for automatic event recognition(e.g., reactor condition monitoring).

      • 담배에 형질발현된 완두 rbcS GENE의 발현

        박승희,우제창 木浦大學校 基礎科學硏究所 1995 基礎科學硏究誌 Vol.13 No.-

        Using a binary vector system with pea rbcS gene and hygromycin phosphotransferase gene for selectable marker, tobacco plant was transformed by means of a leaf disc transformation method. After co-cultivation, bacterial cells were removed by cefotaxim treatment. Transformed shoots were developed from the co-cultivated leaf disc within 1 to 2 weeks in selection media supplemented with 25㎍/㎖ hygromycin and 50㎍/㎖ kanamycin. While normal plants could not grow in the medium with 25㎍/㎖ hygromycin the transformed plants could survive in the medium with 200㎍/㎖ hygromycin. It meant that resistant gene and rbcS gene was expressed in regenerated tobacco plants. Differential protein accumulation of RUBISCO small subunit was not detected by SDS-PAGE.

      • 액상 실리카륨을 혼입한 콘크리트의 파괴특성

        박제선,민창동,김태경,이주형 江原大學校 産業技術硏究所 1995 産業技術硏究 Vol.15 No.-

        The experimental study is conducted to analyze the characteristics of concrete included silica fume. The workability of concrete is controled by the ratio of mixture, such as superplastcizer, based on the constant rates of sand and cement. It is concluded that the strength and the frectu Toughness of concrete with silica fume are very improved.

      • KCI등재
      • KCI등재후보

        전경대원에서 발생한 결핵의 임상 양상

        문창기,박상준,조민구,김영중,김소연,김윤권,정준오,안석진,김은실,서승오,김지훈,최원제,이윤영,박형기,최규영,김현근 대한감염학회 2006 감염과 화학요법 Vol.38 No.6

        Background: The purpose of this study was to document the incidence and clinical characteristics of patients with tuberculosis (TB) in combat and auxiliary police, living in a group, in Korea where the incidence rate of active TB in a general population is higher than in Western countries. Materials and Methods:We retrospectively reviewed the medical records of all tuberculosis patients diagnosed at National Police Hospital from January 2002 through December 2004. Results:In 2002-2004, a total of 156 cases of tuberculosis were identified with the mean (Standard deviation) age of 20.6 (±1.0) years. Of these, 134 (85.9%) patients were registered as new cases, 11 (7.1%) as relapse, 2 (1.3%) as failure, 5 (3.1%) as treatment-after-default cases whereas 4 (2.6 %) patients were not included in any categories. Average annual new TB rate and smear-positive TB rate were 86.5/10^(5) and 17.4/10^(5) person-years, respectively. In 12 of 31 smear-positive cases, time from onset of symptoms to diagnosis was more than 30 days. Two multidrug-resistance TB cases were identified and two suspected outbreak episodes of TB had occurred during 3 years. Conclusion:There was no statistically significant difference in the incidence rate of new cases of TB between the general population aged 20 to 29 years and combat and auxiliary police in Korea. 배경 : 국내 결핵의 발생은 감소 추세에 있으나 여전히 후진국형 발생양상을 보이고 있다. 특히 집단생활을 하는 젊은이들에서 발생하는 결핵의 유행이 간헐적으로 알려지고 있어 우려를 낳고 있다. 이에 저자들은 최근 전경대원의 결핵 발병 양상에 대해 알아보고자 본 연구를 시행하였다. 재료 및 방법 : 2002년 1월부터 2004년 12월까지 3년간 경찰병원에서 결핵 진료를 받은 전경대원의 의무기록을 후향적으로 분석하여 연도별 결핵 신환발생률, 도말양성결핵 신환율, 진단 지연, 집단발병, 다제내성결핵을 조사하였다. 결과 : 연도별 결핵 신환자 수(10만명당 발생추정치)는 2002년 50명(83.6명), 2003년 42명(83.7명), 2004년 42명(93.5명)이었고 도말양성 폐결핵 신환자 수는 2002년 10명(16.7명), 2003년 11명(21.9명), 2004년 6명(13.4명)이었다. 3년간 도말양성 폐결핵 환자는 31명이 있었고 그 중 12명은 호흡기 증상 발생 30일이 지나서 진단을 받았다. 다제내성 결핵은 2명이 있었으며 결핵의 집단발병이 의심되는 사례는 2차례 있었다. 결론 : 전경대원과 20-29세 연령군 일반인의 결핵 신환발생률, 도말양성 폐결핵 발생률의 통계적으로 유의한 차이는 없었다.

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