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        A Comparative Study of Dichloromethane and Ethyl Acetate Root Extracts of <i>Celosia trigyna</i>: Phytochemical and Wound Healing Effect Analyses

        Ofusori Adebimpe Esther,Raharjo Yanuardi,Ofusori David Adesanya,Adekunle Victory Opeyemi 대한창상학회 2023 Journal of Wound Management and Research Vol.19 No.2

        Background: <i>Celosia</i> species have been validated to possess antimicrobial, anti-inflammatory, and antioxidant potential. This study was thus designed to comparatively determine the effect of dichloromethane and ethyl acetate root extracts of <i>Celosia trigyna</i> on Wistar rat wounds created by 8 mm biopsy punches.Methods: Phytochemical screening was performed on dichloromethane and ethyl acetate root extracts of <i>C. trigyna</i>. For animal studies, 25 adult female Wistar rats were randomly divided into five groups (group A-E; n=5). Group A served as the negative control, group B as a positive control, group C received dichloromethane extract (once/day), group D ethyl acetate extract (once/day), and group E was the vehicle control. All extracts and medication were administered topically. Wound area, wound contraction, period of epithelialization, macroscopic analysis, and histological examination were studied.Results: Phytochemical screening showed that saponins and terpenoids were particularly high in dichloromethane extracts while ethyl acetate extracts were highly rich in terpenoids. The results of wound areas, wound contraction, periods of epithelialization, and macroscopic and histological analyses showed that dichloromethane extract, ethyl acetate extract, and penicillin-treated groups showed better remediation respectively in order of efficacy compared to the negative and vehicle control groups. The histological examination revealed an evidence of tissue regeneration and collagen deposition in the extract-treated groups compared to the positive, negative, and vehicle control groups.Conclusion: In conclusion, both extracts of <i>C. trigyna</i> have a better healing potential compared to penicillin treatment with dichloromethane extract having a better wound healing potential than the ethyl acetate extract.

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        Facilitating Conditions in Adopting Big Data Analytics at Medical Aid Organizations in South Africa

        VELA, Junior Vela,SUBRAMANIAM, Prabhakar Rontala,OFUSORI, Lizzy Oluwatoyin Korea Distribution Science Association 2022 The Journal of Industrial Distribution & Business( Vol.13 No.11

        Purpose: This study measures the influence of facilitating conditions on employees' attitudes towards the adoption of big data analytics by selected medical aid organizations in Durban. In the health care sector, there are various sources of big data such as patients' medical records, medical examination results, and pharmacy prescriptions. Several organizations take the benefits of big data to improve their performance and productivity. Research design, data, and methodology: A survey research strategy was conducted on some selected medical aid organizations. A non-probability sampling and the purposive sampling technique were adopted in this study. The collected data was analysed using version 23 of Statistical Package for Social Science (SPSS) Results: the results show that the "facilitating conditions" have a positive influence on employees' attitudes in the adoption of big data analytics Conclusions: The findings of this study provide empirical and scientific contributions of the facilitating conditions issues regarding employee attitudes toward big data analytics adoption. The findings of this study will add to the body of knowledge in this field and raise awareness, which will spur further research, particularly in developing countries.

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