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RISS 인기검색어
- 검색키워드
- 저자 : Mohsen Kalantari (검색결과 3 건)
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Mehrazma, Mitra,Kalantari, Elham,Rezvani, Hamid,Bahar, Babak,Basi, Ali,Razavi, Seyed Mohsen,Rakhshani, Nasser Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.17
Background: HER2/neu overexpression on cell membranes of breast cancer cells is due to HER2/neu gene amplification and it is important to identify potential candidates for anti HER2 therapy with trastuzumab. IHC, FISH and CISH are standard FDA approved assays currently used to determine HER2 status in routine practice. The aim of this study was to determine HER2 gene amplification, using the CISH method in breast carcinoma samples which had IHC +2 reactions. Materials and Methods: This study was conducted from 2008-2010 using 334 consecutive breast carcinoma samples referred from local laboratories to Mehr Hospital. CISH assays were performed for all cases, and IHC tests were also done for determining efficacy and accuracy of local labs. HER2 status in local IHC tests was compared with central IHC and CISH results. Results: Of 334 breast cancer patients, 16 were negative for HER2 IHC (0, +1), 201 cases were equivocal (+2), and 31 positive (+3). Of 334 referral cases, 88 were CISH positive (26.3%) and 246 were CISH negative (73.7%). Of 201 IHC +2 cases, HER2 gene amplification was observed in 42 cases (kappa: 0.42). A 29.9% concordance was found between local IHC and central IHC. Sensitivity and specificity of local IHC were 90% and 53.8%, respectively. Conclusions: Low accuracy of IHC results in local labs was associated with the following factors: using former FDA-approved criteria for HER2 interpretation, utilizing non-validated kits, and lack of any quality assurance program. Therefore, following the new 2014 ASCO/CAP guideline and comprehensive quality assurance should be implemented to ensure accuracy of HER2 testing.
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Applying BIM to support dispute avoidance in managing multi-owned buildings
Jihye Shin,Abbas Rajabifard,Mohsen Kalantari,Behnam Atazadeh 한국CDE학회 2020 Journal of computational design and engineering Vol.7 No.6
With the growth of high-density living, disputes experienced by residents in multi-owned buildings (MOBs) have become an ongoing challenge in urban areas. A significant number of the disputations have found their root cause in the issues concerning improper use and management of MOBs by residents. It stems from their inaccurate understanding of ownership rights that are inherently 3D but using 2D cadastral survey plans, authoritative documents of ownership. This research explores the ability of building information modeling (BIM) to address required information for improving the perception of ownership rights that affect resident behaviors in managing MOBs. An open data model of BIM is extended to accommodate the necessary information for preventing resident misbehaviors that led to dispute cases in Victoria state, Australia. In this study, we implement BIM data of an MOB where a real dispute happened to demonstrate the validity of the enriched data model on the information delivery and an enhanced understanding of ownership rights. It is confirmed that the use of BIM facilitates the alleviation of the misbehaviors by informing residents with accurate communication of ownership rights and could support the avoidance of disputes in MOBs.
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Rohani-Rasaf, Marzieh,Abdollahi, Morteza,Jazayeri, Shima,Kalantari, Naser,Asadi-Lari, Mohsen Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.3
Background: Variation in cancer incidence in geographical locations is due to different lifestyles and risk factors. Diet and socio-economic position (SEP) have been identified as important for the etiology of cancer but patterns are changing and inconsistent. The aim of this study was to investigate correlations of the incidence of common cancers with food groups, total energy, smoking, and SEP. Materials and Methods: In an ecological study, disaggregated cancer data through the National Cancer Registry in Iran (2008) and dietary intake, smoking habits and SEP obtained through a population based survey within the Urban Health Equity Assessment (Urban-HEART) project were correlated across 22 districts of Tehran. Results: Consumption of fruit, meat and dairy products adjusted for energy were positively correlated with bladder, colorectal, prostate and breast and total cancers in men and women, while these cancers were adversely correlated with bread and fat intake. Also prostate, breast, colorectal, bladder and ovarian cancers had a positive correlation with SEP; there was no correlation between SEP and skin cancer in both genders and stomach cancer in men. Conclusions: The incidence of cancer was higher in some regions of Tehran which appeared to be mainly determined by SEP rather than dietary intake. Further individual data are required to investigate reasons of cancer clustering.
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