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      • KCI등재

        Chemical modification of LDH conversion coating with diethyldithiocarbamate as a novel anti-corrosive film for AA2024-T3

        Iman Mohammadi,Taghi Shahrabi,Mohammad Mahdavian,Mazdak Izadi 한국공업화학회 2021 Journal of Industrial and Engineering Chemistry Vol.95 No.-

        Nowadays, layered double hydroxide conversion coatings are a potential eco-friendly alternative forhazardous and carcinogenic chromate conversion coatings. In this work, Zn-Al LDH conversion coating(LDH CC) modified with diethyldithiocarbamate (DEDTC) molecules, as a smart inhibitivefilm, wassynthesized on AA2024-T3. For this purpose, the LDH CC was prepared on the AA2024-T3 by an in-situhydrothermal route, and then intercalated with DEDTC molecules through an anion-exchange procedure. The intercalation of the DEDTC into the structure of the LDH CC was studied using XPS, XRD, ATR-FTIR,SEM-EDS, and TGA techniques. All of the characterization techniques proved the successful intercalationof the DEDTC molecules in the structure of the LDH CC. Results indicated that the chemical modificationtreatment increases in the gallery space of LDH CC by the intercalation of DEDEC molecules in thecoating structure. Also, electrochemical tests were implemented in 3.5 wt. % NaCl media to study theanti-corrosion performance of the coatings. The electrochemical test results showed that the presence ofthe DEDTC molecules dramatically enhanced the anti-corrosion behavior of the LDH CC due to theinduction of the active inhibition mechanism.

      • KCI등재

        Crocin Improves Oxidative Stress by Potentiating Intrinsic Anti-Oxidant Defense Systems in Pancreatic Cells During Uncontrolled Hyperglycemia

        Habib Yaribeygi,Ali Noroozadeh,Mohammad Taghi Mohammadi,Thomas P. Johnston,Amirhossein Sahebkar 대한약침학회 2019 Journal of pharmacopuncture Vol.22 No.2

        Introduction: Oxidative stress (OS) during uncontrolled hyperglycemia has a pivotal role in pancreatic dysfunction. Our study aimed to demonstrate that crocin can potentiate anti-oxidant defense systems of pancreatic cells to improve oxidative stress. Methods: Male Wistar rats were divided randomly into four groups: a normal group, a normal-treated group, a diabetic group and a diabetic-treated group (n = 6 rats per group). Diabetes was induced by a single dose of streptozotocin (45 mg/kg/IV). The treated groups received crocin daily for 8 weeks (40 mg/kg/IP). At the end of the experiment, rats were sacrificed and pancreas tissue was obtained. Subsequently, the concentrations of malondialdehyde (MDA), nitrate and glutathione as well as the enzymatic activities of catalase and superoxide dismutase (SOD) were determined in all animals. Data were analyzed by two-way ANOVA with appropriate post hoc testing and a probability value of P < 0.05was considered to represent a statistically significant difference in mean values. Results: Uncontrolled hyperglycemia weakened the anti-oxidant system by decreasing SOD and catalase enzyme activity in pancreatic tissues and induced OS by increasing the MDA content in diabetic non-treated animals. Crocin potentiated the anti-oxidant defense system by increasing the activity of both SOD and catalase, and improved OS by diminishing MDA production in pancreatic cells of rats contained in the diabetic-treated group. Conclusion: Based on our results, it is concluded that uncontrolled hyperglycemia can weaken the anti-oxidant defense system and cause the development of OS. Also, crocin can improve OS in pancreatic cells by potentiating the anti-oxidant defense system.

      • SCOPUSKCI등재

        Crocin Improves Oxidative Stress by Potentiating Intrinsic Anti-Oxidant Defense Systems in Pancreatic Cells During Uncontrolled Hyperglycemia

        Yaribeygi, Habib,Noroozadeh, Ali,Mohammadi, Mohammad Taghi,Johnston, Thomas P.,Sahebkar, Amirhossein KOREAN PHARMACOPUNCTURE INSTITUTE 2019 Journal of pharmacopuncture Vol.22 No.2

        Introduction: Oxidative stress (OS) during uncontrolled hyperglycemia has a pivotal role in pancreatic dysfunction. Our study aimed to demonstrate that crocin can potentiate anti-oxidant defense systems of pancreatic cells to improve oxidative stress. Methods: Male Wistar rats were divided randomly into four groups: a normal group, a normal-treated group, a diabetic group and a diabetic-treated group (n = 6 rats per group). Diabetes was induced by a single dose of streptozotocin (45 mg/kg/IV). The treated groups received crocin daily for 8 weeks (40 mg/kg/IP). At the end of the experiment, rats were sacrificed and pancreas tissue was obtained. Subsequently, the concentrations of malondialdehyde (MDA), nitrate and glutathione as well as the enzymatic activities of catalase and superoxide dismutase (SOD) were determined in all animals. Data were analyzed by two-way ANOVA with appropriate post hoc testing and a probability value of P < 0.05 was considered to represent a statistically significant difference in mean values. Results: Uncontrolled hyperglycemia weakened the anti-oxidant system by decreasing SOD and catalase enzyme activity in pancreatic tissues and induced OS by increasing the MDA content in diabetic non-treated animals. Crocin potentiated the anti-oxidant defense system by increasing the activity of both SOD and catalase, and improved OS by diminishing MDA production in pancreatic cells of rats contained in the diabetic-treated group. Conclusion: Based on our results, it is concluded that uncontrolled hyperglycemia can weaken the anti-oxidant defense system and cause the development of OS. Also, crocin can improve OS in pancreatic cells by potentiating the anti-oxidant defense system.

      • SCIESCOPUSKCI등재

        Neutron dosimetry with a pair of TLDs for the Elekta Precise medical linac and the evaluation of optimum moderator thickness for the conversion of fast to thermal neutrons

        Marziyeh Behmadi,Sara Mohammadi,Mohammad Ehsan Ravari,Aghil Mohammadi,Mahdy Ebrahimi Loushab,Mohammad Taghi Bahreyni Toossi,Mitra Ghergherehchi Korean Nuclear Society 2024 Nuclear Engineering and Technology Vol.56 No.2

        Introduction: In this study, TLD 600 and TLD 700 pairs were used to measure the neutron dose of Elekta Precise medical linac. To this end, the optimum moderate thickness for the conversion of fast to thermal neutrons were evaluated. Materials and methods: <sup>241</sup>Am-Be and <sup>252</sup>Cf sources were simulated to calculate the optimum thicknesses of the moderator for the conversion of maximum fast neutrons (FN) into thermal neutrons (TN). Pair TLDs were used to measure F&TN doses for three different field sizes at four depths of the medical linac. Results: The maximum thickness of the moderator was optimized at 6 cm. The measurement results demonstrated that the TN dose increased with the expansion of field size and depth. The FN dose, which was converted TN, exhibits behaviors comparable to the TN due to its nature. Conclusion: This study presents the optimum thickness for the moderator to convert FN into TN and measure F&TN using TLDs.

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