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      • Load Control between PV Power Plants and Diesel Generators

        Mohamed Khalil Abdalla MohamedAli,AISHA HASSAN ABDALLA HASHIM,OTHMAN KHALIFA International Journal of Computer ScienceNetwork S 2024 International journal of computer science and netw Vol.24 No.6

        Introducing renewable energy sources, such as wind and photovoltaic arrays, in microgrids that supply remote regions with electricity represents a significant leap in electricity generation. Combining photovoltaic panels and diesel engines is one of the most common ways to supply electricity to rural communities. Such hybrid systems can reduce the cost of electricity generation in these remote power systems because they use free energy to balance the power generated by diesel engines. However, the combination of renewable energy sources and diesel engines tends to complicate the sizing and control of the entire system due to the intermittent nature of renewable energy sources. This study sought to investigate this issue in depth. It proposes a robust hybrid controller that can be used to facilitate optimum power sharing between a PV power source and diesel generators based on the dynamics of the available PV energy at any given time. The study also describes a hybrid PV-diesel power plant's essential functional parts that produce electricity for a microgrid using a renewable energy source. Power control needs to be adjusted to reduce the cost of power generation.

      • Sensitive Angiogenesis Imaging of Orthotopic Bladder Tumors in Mice Using a Selective Magnetic Resonance Imaging Contrast Agent Containing VEGF121/rGel

        Cho, Eun-Jin,Yang, Jaemoon,Mohamedali, Khalid A.,Lim, Eun-Kyung,Kim, Eun-Jung,Farhangfar, Carol J.,Suh, Jin-Suck,Haam, Seungjoo,Rosenblum, Michael G.,Huh, Yong-Min Lippincott Williams Wilkins, Inc. 2011 Vol. No.

        OBJECTIVES:: To investigate the efficiency of magnetic resonance imaging (MRI) contrast agents employing vascular endothelial growth factor (VEGF121)/rGel conjugated MnFe2O4 nanocrystals for imaging of neovasculature using a bladder tumor model. MATERIALS AND METHODS:: VEGF121/rGel was conjugated to MnFe2O4 nanoparticles (MNPs). The targeting efficiency and detection capability of the VEGF121/rGel-MNPs were investigated in both KDR-deficient (253JB-V) and KDR-overexpressing (PAE/KDR) cells using MRI. The internalization of VEGF121/rGel-MNPs into cells was confirmed by electron microscopy. Their phosphorylation ability and cytotoxicity were compared with unconjugated VEGF121/rGel. The orthotopic tumor mice were established by implanting low KDR-expressing 253JB-V cells into the bladder dome. After tail-vein injection of VEGF121/rGel-MNPs, the MR signal enhancement of intratumoral vessels by VEGF121/rGel-MNPs was observed and inhibition test using VEGF121 was also conducted. Ex vivo MR imaging of tumor tissue, and a fluorescence immunostaining study was also performed. RESULTS:: The water-soluble VEGF121/rGel-MNPs (44.5 ± 1.2 nm) were stably suspended in the biologic media and exhibited a high relaxivity coefficient (423 mMs). They demonstrated sufficient targeting capability against KDR-overexpressing PAE/KDR cells, as confirmed by dose-dependent MR images and VEGF121 inhibition tests. The phosphorylation activity of KDR and cytotoxicity of VEGF121/rGel-MNPs were evaluated. VEGF121/rGel-MNPs successfully targeted the tumor and provided accurate anatomic details through (i) acquisition of clear neoangiogenic vascular distributions and (ii) obvious enhancement of the MR signal in T2*-weighted images. Immunostaining and blocking studies demonstrated the specific targeting ability of VEGF121/rGel-MNPs toward intratumoral angiogenesis. CONCLUSIONS:: Synthesized VEGF121/rGel-MNPs as targeted MR imaging contrast agents can be specifically delivered to tumors and bind to KDR-expressing angiogenic tumor vessels.

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