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IVIG Treatment Response and Age are Important for the Prognosis of Pediatric Immune Thrombocytopenia
Min Gi Sakong,Ji Hoon Park,Sang Beom Son,Yu Kyung Kim,Jae Min Lee 대한소아혈액종양학회 2022 Clinical Pediatric Hematology-Oncology Vol.29 No.2
Background: This study aimed to identify chronicity predictors of pediatric primary immune thrombocytopenia (ITP).Methods: This study retrospectively reviewed the medical records of patients with pri-mary pediatric ITP admitted to a tertiary medical center between 2010 and 2021. Forty-five patients with a platelet count <20,000/μL at the time of diagnosis who were treated with intravenous immunoglobulin (IVIG) were enrolled in this study.Results: According to the disease phase, 28, 6, and 11 patients were classified into the newly diagnosed (ND), persistent, and chronic groups, respectively. The number of patients over 6 years of age was significantly higher in the chronic group than in the ND and persistent groups. After 14 days of IVIG treatment, more patients had a complete response in the non-chronic groups than in the chronic group. In uni-variate analysis of risk factor for chronic ITP, age 6 years or older and IVIG dose <2 g/kg were found to be risk factors for chronic ITP, and these two factors were also confirmed as significant risk factors in multivariate analysis.Conclusion: In conclusion, in our study, patients over 6 years of age, and those who received IVIG doses less than 2 g/kg were more likely to progress to chronic ITP.
LCD Backlight 응용을 위한 Charge Pump Half-Bridge Inverter 회로
박규민(Kyu-Min Park),노정욱(Chung-Wook Roh),한상규(Sang-Kyoo Han),홍성수(Sung-Soo Hong),사공석진(Sug-Chin Sakong),권기현(Gi-Hyun Kwon),이효범(Hyo-Bum Lee) 전력전자학회 2007 전력전자학술대회 논문집 Vol.- No.-
본 논문은 LCD Backlight 구동을 위한 새로운 방식의 회로를 제안한다. 제안된 회로는 Charge Pump 캐패시터를 이용한 Half-Bridge 타입의 인버터로 Full Bridge 회로와 동등한 성능을 갖는다. 제안 회로는 넓은 입력 범위와 넓은 부하 범위에서 영전압 스위칭(ZVS) 확보가 가능해서 인버터의 고효율 동작이 확보되고, MOSFET의 surge 및 noise를 저감시킨다. 제안된 회로의 동작 원리를 설명하고, 시뮬레이션 및 40” LCD 패널에 실제 적용 실험하여, 회로의 동작을 입증하였다.