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      • KCI등재

        Sudden Death in Pediatric Populations

        Mei-Hwan Wu 대한심장학회 2010 Korean Circulation Journal Vol.40 No.6

        Sudden death (SD) in children is rarer than in adults. In the pediatric population, SD accounts for less than one tenth of deaths from all causes. SD in infants is a separate entity commonly termed “sudden infant death syndrome (SIDS)”. Previous studies on SD in pediatric patients primarily focused on infants and showed that the incidence of SIDS was much lower in Asian countries than in Western ones. However, these differences diminished after educational campaigns such as the back to sleep act in the late 1980s to early 1990s. The incidence of SIDS from Western reports has decreased from 2.69 to around 0.5-0.24 per 1,000 live births. Beyond infancy, the annual incidence of SD ranges from 1.3 to 7.5 per 100,000. In 2009, two population-based studies, one from Taiwan and the other from the US, explored the epidemiological profile of SD in children. The child health care indexes of these two countries are similar, but the annual incidence of pediatric SD was 7.5 and 2.7 per 100,000 in the USA and Taiwan,respectively. The implications of ethic-related differences requires further confirmation. Around 40% of pediatric SD could be from cardiac causes, either diagnosed or undiagnosed. Risk stratification for cardiac SD and patient selection for implantable cardioverter-defibrillator (ICD) therapy are recommended. However, the adoption of ICD as primary prevention for SD in children is still a challenging issue. Early detection of undiagnosed cardiac risk may be facilitated by cardiac screening either in newborns or the school-age population to better manage the risk of SD. However, the efficacy of such screening remains still controversial.

      • P型 α-多孔 SiC. 的光致發光光潽硏究

        이기환,김영유,두영뢰,우배매 公州大學校 基礎科學硏究所 1998 自然科學硏究 Vol.7 No.-

        The photoluminescence (PL) spectra from p-type a-porous silicon carbides prepared under UV photo-assisted process and under dark-current condition are investigated in detail. Emission bands with peak energies of 2.35, 2.50, 2.70, and 3.43 are resolved. The PL stability in tune and the PL difference arising from different tuning excitation energies are studied. It is found that the PL spectra of the a-porous silicon carbide depend strongly on the preparation conditions for electrochemical etching. The PL spectrum of the sample prepared under photo-assisted process has an enhancement on the lower-energy side of the emission; on the contray, another one under dark-current condition has an enhancement at the higher energy side, and the former stability is better than the latter one, and the latter PL intensity decreases with the increase of the time in the air. The reasons about these differences are discussed.

      • KCI등재후보

        안구건조증 환자에서 국소 테스토스테론 젤의 치료효과

        허환,강인성,오미화,윤경철.Hwan Heo. M.D.. In Sung Kang. M.D.. Mei Hwa Wu. M.D.. Kyung Chul Yoon. M.D. 대한안과학회 2006 대한안과학회지 Vol.47 No.8

        Purpose: To evaluate the therapeutic effect of topical testosterone gel application to periocular area in dry eye. Methods: Thirty-four eyes of 17 patients with refractory dry eye were included. Five patients had Sjogren`s syndrome and 12 were non-Sjogren`s syndrome patients. Testosterone gel was applied on the periocular area three times a day. Symptom score corneal sensitivity test (CST), tear film break-up time (BUT), basal tear secretion test (BST), fluorescein staining, tear clearance test (TCR), and conjunctival impression cytology were checked and evaluated before, one month after and two months after treatment. Results: The mean symptom score before topical testosterone gel application was 3.44±0.70; it was 2.88±0.84 at 1 month after application and 2.03±1.09 at 2 months after application. The improvement of tear film parameters including BUT, tear clearance rate, fluorescein staining score, conjunctival metaplasia and goblet cell density was statistically significant (P<0.05) at one and two months after treatment but neither BST nor CST was improved with statistically significance. There was no difference in the therapeutic effect of topical testosterone gel between Sjogren`s syndrome and non-Sjogren`s dry eye patients. Conclusions: The function of tear film and the integrity of ocular surface improved after topical application of testosterone gel in dry eye patients. Topical testosterone gel application may be an effective adjuvant therapy for the treatment of dry eye.

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