Investigation of Olive Accessions using Nuclear Magnetic Resonance

SeongMinKim,MichaelJ.Mccarthy2 전북대학교 농업과학기술연구소 2010 농업생명과학연구 Vol.41 No.1

In this study we used NMR to assess oil content in the 201 olive accessions in the Davis- National Clonal Germplasm Repository(NCGR) collection. Characterization of the olive collection will greatly facilitate stakeholder utilization of this important collection. Since oil content varies widely in olive accessions and oil production is the most important use of olives worldwide, characterization of oil content is critical data for the NCGR olive collection. Oil and moisture content were measured using a proton spectra and integrating this to obtain total signal intensity from the oil and moisture. Oil content is one of the most commercially important attributes of olive genotypes. NMR has been established as an accurate and rapid method for detecting oil content in intact olives. These data were collected at three dates, at monthly intervals, targeting the date of 90% color development for each accession. CPMG pulse sequence was used to acquire signal in time domain and T2 was calculated using a bi-exponential curve fitting method. Inversion recovery pulse sequence was used to acquire spectroscopic data and T1 were calculated for water and oil absorption from proton spectra. The relaxation time constants are useful indexes for examining the state of olive accessions.

National parks, protected areas and biodiversity conservation in North Korea: opportunities for international collaboration

Christopher McCarthy,James Banfill,Buho Hoshino 국립중앙과학관 2021 Journal of Asia-Pacific Biodiversity Vol.14 No.3

National parks and protected areas represent one of the best ways to safeguard nature and preservebiodiversity, especially endemic and endangered species. Currently, more than 110 countries have someform of protected areas within their borders. North Korea’s comprehensive network of national parksand protected areas are rich in biodiversity and ecological value; however, contemporary research on theintegrity of North Korea’s protected lands is incomplete. In this paper, we utilize a remote sensingapproach to explore North Korea’s protected area system and investigate the current state of biodiversityconservation. We find that several key biodiversity areas have experienced severe tree loss and habitatfragmentation since 2000, indicating that the effectiveness of national park governance andmanagement toward guarding against biodiversity loss is inadequate. To address the issue of biodiversityconservation, we recommend pathways for international cooperation aimed at enhancing conservationefforts and comment on the steps North Korea can take to achieve the United Nations Convention onBiological Diversity’s Aichi Targets and Sustainable Development Goals.

Teaching Creativity: A Look Beyond Counseling

John McCarthy 한국상담학회 2017 Journal of Asia Pacific counseling Vol.7 No.1

Interest in creativity within counseling dates to the 1970s. However, attention to the teaching of such courses, particularly those geared toward creativity and creative problem-solving in counselor education, is limited. Counselor educators may benefit by having a broader understanding of the development of these courses in other domains, including those classes taught at an undergraduate level and others offered in institutions in other countries.

THE MANAGEMENT OF ECONOMIC DEVELOPMENT ASSISTANCE IN THE DEMOCRATIC PEOPLE’S REPUBLIC OF KOREA

ThomasF.McCarthy 경남대학교 극동문제연구소 2002 ASIAN PERSPECTIVE Vol.26 No.1

This article suggests how the Democratic People’s Republic of Korea might manage its relationships with the International Monetary Fund and the major multilateral development banks. The DPRK can handle conceptual economic policy formulation and traditional investment planning work better than most outside observers think; but it will need to strengthen institutional competency. Though many observers expect that the DPRK's relationships with international financial institutions will be driven primarily by a process of Korean economic integration, the DPRK’s political priorities may well be to use those institutions’ resources to increase its range of options by building bridges to China, Russia, and the European Union. The international financial institutions will be better able to help the DPRK deal with the political and institutional dimensions of development if they recognize the potentially constructive role of China. The United States needs to relax its restrictions on the financial institutions’ preparatory work in the DPRK if it wants an economic opening to get under way.

Preserving the Gobi: Identifying potential UNESCO world heritage in Mongolia’s Gobi Desert

Christopher McCarthy,Troy Sternberg,Buho Hoshino,James Banfill,Erdenebuyan Enkhjargal,코나가야 유끼,Simon Phillips 국립중앙과학관 2022 Journal of Asia-Pacific Biodiversity Vol.15 No.4

The Gobi Desert, Asia’s largest desert, covers roughly 1,300,000 square kilometers across southernMongolia and northern China. One of the world’s most iconic deserts, the Gobi is a functioning, healthyecosystem home to spectacular landscapes that support an impressive variety of biological diversity,including many rare and endangered species. Human activity in the Gobi has existed for at least5,000 years and several culturally and historically significant archeological sites have been documentedin the region; the Gobi continues to support an ancient and enduring nomadic lifestyle. Prehistoric tracesof ancient life are also widespread, making the Gobi a hotspot for fossil discoveries. Despite a wealth ofnatural and cultural heritage the Gobi Desert in Mongolia lacks any recognition as UNESCO WorldHeritage. This article explores the natural and cultural heritage of the Gobi Desert in Mongolia and usingUNESCO’s framework for “Outstanding Universal Value,” identifies several sites with exceptionalgeological, ecological, and ethnological features that we believe meet the criteria for World Heritagestatus. In the face of looming threats from human interference and climate change, increased recognitionand appreciation of Gobi Desert landscapes is crucial to ensure the long-term protection of these irre placeable sources of life and inspiration.

Dextromethorphan-bupropion (Auvelity) for the Treatment of Major Depressive Disorder

Brian McCarthy,Hannah Bunn,Morgan Santalucia,Charlotte Wilmouth,Andrew Muzyk,Colin M. Smith 대한정신약물학회 2023 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.21 No.4

Depression is a significant cause of morbidity and mortality globally. Although various pharmacologic options exist for depression, treatments are limited by delayed or incomplete therapeutic response, low rates of remission, and adverse effects necessitating effective, fast-acting, and better tolerated alternatives. The purpose of this review is to describe the safety and efficacy of dextromethorphan-bupropion (Auvelity), a Food and Drug Administration approved treatment for major depressive disorder in adults. Dextromethorphan modulates glutamate signaling through uncompetitive antagonism of N-methyl-D-aspartate receptors and sigma-1 agonism, while bupropion increases the bioavailability of dextromethorphan by CYP2D6 inhibition. In a phase 3 trial with dextromethorphan-bupropion 45−105 mg for patients with major depressive disorder saw significant reductions in their Montgomery-Åsberg Depression Rating Scale total scores compared to placebo. A phase 2 trial comparing dextromethorphan-bupropion 45−105 mg to bupropion monotherapy led to significant reduction in Montgomery-Åsberg Depression Rating Scale score. Changes in Montgomery-Åsberg Depression Rating Scale with dextromethorphan-bupropion were seen within two weeks in both clinical trials. Remission and response rates were significantly higher with dextromethorphan-bupropion in both studies. The medication was well-tolerated in both trials, with the most common adverse events being rated as mild-to-moderate. Two long-term, open-label studies with dextromethorphan-bupropion saw large reductions in Montgomery-Åsberg Depression Rating Scale scores that were maintained through 12 and 15 months of treatment. In both long-term studies, remission rates approached 70%, while response rates were greater than 80%. These data suggest that dextromethorphan-bupropion is an effective, fast-acting, and well tolerated option for depression treatment and produced remission in a large percentage of patients.

머신비전과 딥러닝 기반의 양돈생육프로그램 개발 및 양돈생육환경 개선

백대선,임성훈 대한산업공학회 2019 대한산업공학회 춘계학술대회논문집 Vol.2019 No.4

The Importance of Global Studies of the Genetics of Type 2 Diabetes

Mark I. McCarthy 대한당뇨병학회 2011 Diabetes and Metabolism Journal Vol.35 No.2

Genome wide association analyses have revealed large numbers of common variants influencing predisposition to type 2 diabetes and related phenotypes. These studies have predominantly featured European populations, but are now being extended to samples from a wider range of ethnic groups. The transethnic analysis of association data is already providing insights into the genetic, molecular and biological causes of diabetes, and the relevance of such studies will increase as human discovery genetics increasingly moves towards sequencing-based approaches and a focus on low frequency and rare variants.

Need for Logic Instruction in Schools

Sherri N. McCarthy-Tucker 대한사고개발학회 1998 The International Journal of Creativity & Problem Vol.8 No.2

This paper traces the development of teaching logic and critical thinking in Western education since classical times, with particular emphasis on developments in the United States during the twentieth century. It suggests that teaching logic, critical thinking and planning skills are imperative for future generations to function well in a global communicy and summarizes a variety of programs and strategies that have been incorporated into Western educational practices in the areas of language arts, science, math and social studies. These programs critiqued from the perspective of developmental psychology. Strengths and weaknesses are addressed. And how formal and informal logic have (or, more frequently, have not) been appropriately integrated into the U.S. public school curriculum is discussed, with recommendations for future consideration.

Teaching Logic to Adolescents to Improve Thinking Skills

Sherri N. McCarthy-Tucker 대한사고개발학회 1998 The International Journal of Creativity & Problem Vol.8 No.1

Critical thinking and planning skills are vital to a successful global community. Lack of critical thinking skills among adolescents is a major concern. According to developmental theory, lack of exposure to logic during adolescence may account, in part, for poor thinking skills. Lack of training in formal logic is hypothesized to be one reason for poor thinking skills among US youth. To test this, 190 adolescents enrolled in a multicultural urban school were assigned to one of three conditions. All students were pre-tested using the Ravens Progressive Matrices Test (Raven, 1986), the Test of Logical Thinking (Tobin, 1984), a test designed for the study to measure understanding of formal logic and a Likert-type scale to assess self-perception of thinking. One group received instruction in logic. The second group received instruction from a critical thinking curriculum. The third group served as control, receiving standard subject一area instruction only. After over four months of instruction, all tests were re administered. Students instructed in logic performed significantly better on all measures than either of the other groups. This suggests formal logic instruction may improve adolescents thinking skills. This research, and its implications for curriculum and teacher education, are discussed.