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- 저자 : Matthew R. Fusco (검색결과 4 건)
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Preoperative Embolization of Extra-axial Hypervascular Tumors with Onyx
Matthew R. Fusco,Bradley A. Gross,Mohamed M. Salem,Arra S. Reddy,Christopher S. Ogilvy,Ekkehard M. Kasper,Ajith J. Thomas 대한뇌혈관외과학회 2016 Journal of Cerebrovascular and Endovascular Neuros Vol.18 No.1
Objective:Preoperative endovascular embolization of intracranial tumors is performed to mitigate anticipated intraoperative blood loss. Although the usage of a wide array of embolic agents, particularly polyvinyl alcohol (PVA), has been described for a variety of tumors, literature detailing the efficacy, safety and complication rates for the usage of Onyx is relatively sparse. Materials and Methods:We reviewed our single institutional experience with pre-surgical Onyx embolization of extra-axial tumors to evaluate its efficacy and safety and highlight nuances of individualized cases. Results:Five patients underwent pre-surgical Onyx embolization of large or giant extra-axial tumors within 24 hours of surgical resection. Four patients harbored falcine or convexity meningiomas (grade I in 2 patients, grade II in 1 patient and grade III in one patient), and one patient had a grade II hemangiopericytoma. Embolization proceeded uneventfully in all cases and there were no complications. Conclusion:This series augments the expanding literature confirming the safety and efficacy of Onyx in the preoperative embolization of extra-axial tumors, underscoring its advantage of being able to attain extensive devascularization via only one supplying pedicle.
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Middle Meningeal Artery Arising from the Basilar Artery
Mohamed M. Salem,Matthew R. Fusco,Parviz Dolati,Arra S. Reddy,Bradley A. Gross,Christopher S. Ogilvy,Ajith J. Thomas 대한뇌혈관외과학회 2014 Journal of Cerebrovascular and Endovascular Neuros Vol.16 No.4
Various anomalies for the origin of the middle meningeal artery (MMA)have been described in the literature. However, origin of the MMA fromthe basilar trunk is an extremely rare variant. We report on a 54-year-oldfemale who presented with frequent headaches; magnetic resonanceimaging showed a right parietal meningioma. The abnormal origin of themiddle meningeal artery from the basilar artery was diagnosed by angiographyperformed for preoperative embolization of the tumor. We reporton the case with a review of the embryologic basis, possible explanationsfor this aberrant origin, and its clinical implications.
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Michelle H. Chua,Ajith J. Thomas,Matthew R. Fusco,Christopher S. Ogilvy 대한뇌혈관외과학회 2014 Journal of Cerebrovascular and Endovascular Neuros Vol.16 No.4
Variations of the anterior cerebral artery-anterior communicating arterycomplex are commonly identified in aneurysm surgery. An infraopticcourse of the anterior cerebral artery is exceedingly rare. Robison first describedthis anomaly from an anatomic dissection in 1959. A unilateralanomalous infraoptic anterior cerebral artery is more common than anomaliesof bilateral infraoptic anterior cerebral arteries. We present the case of anunruptured aneurysm at the anterior communicating artery in a patientwith bilateral infraoptic anterior cerebral arteries, identified by computedtomography angiography and verified during surgery. Implications foraneurysm formation and surgical treatment are discussed.
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Ahn Seoiyoung,Roth Steven G.,Jo Jacob,Ko Yeji,Mummareddy Nishit,Fusco Matthew R.,Chitale Rohan V.,Froehler Michael T. 대한신경중재치료의학회 2023 Neurointervention Vol.18 No.3
Purpose: Low levels of low-density lipoprotein cholesterol (LDL-C) have been suggested to increase the risk of hemorrhagic transformation (HT) following acute ischemic stroke. However, the literature on the relationship between LDL-C levels and post-thrombectomy HT is sparse. The aim of our study is to investigate the association between LDL-C and delayed parenchymal hematoma (PH) that was not seen on immediate post-thrombectomy dual-energy computed tomography (DECT).Materials and Methods: A retrospective analysis was conducted on all patients with anterior circulation large vessel occlusion who underwent thrombectomy at a comprehensive stroke center from 2018–2021. Per institutional protocol, all patients received DECT immediately post-thrombectomy and magnetic resonance imaging or CT at 24 hours. The presence of immediate hemorrhage was assessed by DECT, while delayed PH was assessed by 24-hour imaging. Multivariable analysis was performed to identify predictors of delayed PH. Patients with hemorrhage on immediate post-thrombectomy DECT were excluded to select only those with delayed PH.Results: Of 159 patients without hemorrhage on immediate post-thrombectomy DECT, 18 (11%) developed delayed PH on 24-hour imaging. In multivariable analysis, LDL-C (odds ratio [OR], 0.76; P=0.038; 95% confidence interval [CI], 0.59–0.99; per 10 mg/dL increase) independently predicted delayed PH. High-density lipoprotein cholesterol, triglyceride, and statin use were not associated. After adjusting for potential confounders, LDL-C ≤50 mg/dL was associated with an increased risk of delayed PH (OR, 5.38; P=0.004; 95% CI, 1.70–17.04), while LDL-C >100 mg/dL was protective (OR, 0.26; P=0.041; 95% CI, 0.07–0.96).Conclusion: LDL-C ≤50 mg/dL independently predicted delayed PH following thrombectomy and LDL-C >100 mg/dL was protective, irrespective of statin. Thus, patients with low LDL-C levels may warrant vigilant monitoring and necessary interventions, such as blood pressure control or anticoagulation management, following thrombectomy even in the absence of hemorrhage on immediate post-thrombectomy DECT.
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