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Comfort and Infection Control of Chitosan-impregnated Cotton Gauze as Wound Dressing
Jefferson M. Souza,Mariana Henriques,Pilar Teixeira,Margarida M. Fernandes,Raul Fangueiro,Andrea Zille 한국섬유공학회 2019 Fibers and polymers Vol.20 No.5
The aim of this study was to evaluate the thermo-physiological comfort properties of surgical cotton gauze coatedwith chitosan (CH) and its effectiveness for the prevention of bacterial colonization. Gauze was coated with CH at massfractions of 0.50, 0.25, 0.125, 0.10, 0.063 wt% and the friction, flexibility, thermal, moisture management and mechanicalproperties were evaluated. The best performing gauze in terms of comfort (0.125 wt%) was further evaluated for its ability toinhibit the growth of microorganisms such as bacteria and yeast. Results indicate that the functionalized medical gauze couldinduce low friction on the wound bed allowing a good degree of moisture and high absorption capacity of wound exudates. Moreover, it shows antimicrobial properties against medical-relevant pathogens. This biofunctional medical gauzedemonstrates to deliver an efficient antimicrobial coating and promote the best conditions for maintenance of the woundmicroenvironment.