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Eunice Jia-Shiow Yuan,Shiau-Shian Huang,Chia-An Hsu,Jiing-Feng Lirng,Tzu-Hao Li,Chia-Chang Huang,Ying-Ying Yang,Chung-Pin Li,Chen-Huan Chen 한국보건의료인국가시험원 2023 보건의료교육평가 Vol.20 No.-
Purpose Coronavirus disease 2019 (COVID-19) has heavily impacted medical clinical education in Taiwan. Medical curricula have been altered to minimize exposure and limit transmission. This study investigated the effect of COVID-19 on Taiwanese medical students’ clinical performance using online standardized evaluation systems and explored the factors influencing medical education during the pandemic. Methods Medical students were scored from 0 to 100 based on their clinical performance from 1/1/2018 to 6/31/2021. The students were placed into pre-COVID-19 (before 2/1/2020) and midst-COVID-19 (on and after 2/1/2020) groups. Each group was further categorized into COVID-19-affected specialties (pulmonary, infectious, and emergency medicine) and other specialties. Generalized estimating equations (GEEs) were used to compare and examine the effects of relevant variables on student performance. Results In total, 16,944 clinical scores were obtained for COVID-19-affected specialties and other specialties. For the COVID-19-affected specialties, the midst-COVID-19 score (88.51–3.52) was significantly lower than the pre-COVID-19 score (90.14–3.55) (P<0.0001). For the other specialties, the midst-COVID-19 score (88.32–3.68) was also significantly lower than the pre-COVID-19 score (90.06–3.58) (P<0.0001). There were 1,322 students (837 males and 485 females). Male students had significantly lower scores than female students (89.33–3.68 vs. 89.99–3.66, P=0.0017). GEE analysis revealed that the COVID-19 pandemic (unstandardized beta coefficient=-1.99, standard error [SE]=0.13, P<0.0001), COVID-19-affected specialties (B=0.26, SE=0.11, P=0.0184), female students (B=1.10, SE=0.20, P<0.0001), and female attending physicians (B=-0.19, SE=0.08, P=0.0145) were independently associated with students’ scores. Conclusion COVID-19 negatively impacted medical students' clinical performance, regardless of their specialty. Female students outperformed male students, irrespective of the pandemic.
Prince, Martin R.,Lee, Hae Giu,Lee, Chang-Hee,Youn, Sung Won,Lee, In Ho,Yoon, Woong,Yang, Benqiang,Wang, Haiping,Wang, Jin,Shih, Tiffany Ting-fang,Huang, Guo-Shu,Lirng, Jiing-Feng,Palkowitsch, Petra Springer Berlin Heidelberg 2017 EUROPEAN RADIOLOGY Vol.27 No.1
<P><B>Objectives</B></P><P>To investigate the safety and tolerability of gadobutrol at the recommended dose in patients requiring contrast-enhanced magnetic resonance imaging/angiography (MRI/MRA) in the routine setting.</P><P><B>Methods</B></P><P>GARDIAN prospectively enrolled 23,708 patients undergoing routine gadobutrol-enhanced MRI/MRA for approved indications at 272 study centres in Europe, Asia, North America, and Africa and monitored for adverse events.</P><P><B>Results</B></P><P>Median gadobutrol dose was 0.11 mmol/kg body weight. The overall incidence of adverse drug reactions (ADRs) was 0.7 % (<I>n</I> = 170 patients), with similar incidences in patients with renal impairment or cardiac disease, from different geographic regions and in different gadobutrol dose groups. Patients at risk for contrast media reaction had an ADR incidence of 2.5 %. Five patients (0.02 %) experienced serious adverse events, four were drug-related. One patient experienced a fatal anaphylactoid shock, assessed to be related to injection of gadobutrol. The contrast quality of gadobutrol-enhanced images was rated by treating physicians as good or excellent in 97 % cases, with similar ratings in all patient subgroups and indications.</P><P><B>Conclusions</B></P><P>The GARDIAN study shows that gadobutrol at the recommended dose is well tolerated across a large, diverse patient population.</P><P><B>Key points</B></P><P>• <I>Gadobutrol at recommended dose shows low rates of adverse drug reactions</I></P><P>• <I>Gadobutrol demonstrates a uniform safety profile across diverse patient groups</I></P><P>• <I>Gadobutrol provides excellent contrast quality in routine practice</I></P>